SpaceRef

SpaceRef


NASA Spaceline Current Awareness December 5, 2003

Status Report From: NASA Office of Biological and Physical Research (OBPR)
Posted: Monday, December 8, 2003

1

Note (#1)

This paper is a comprehensive review of published results of ground-based models of muscle unweighting and comparison with space flight effects.

For a sample of journal articles reporting results of space flight experiments with muscle published in the last ten years, click here.


Adams GR, Caiozzo VJ, Baldwin KM.
Skeletal muscle unweighting: spaceflight and ground-based models.
J Appl Physiol. 2003 Dec;95(6):2185-201. Invited review.
(PI: K.M. Baldwin/Biomedical Research and Countermeasures)

2
Venkatesh AK, Zhang AX, Mansour J, Kubatina L, Oh CH, Blasche G, Selim Unlu M, Balamore D, Jolesz FA, Goldberg BB, Albert MS.
MRI of the lung gas-space at very low-field using hyperpolarized noble gases.
Magn Reson Imaging. 2003 Sep;21(7):773-6.
(PI: M.S. Albert/Biomedical Research and Countermeasures)

3
Ling PD, Vilchez RA, Keitel WA, Poston DG, Peng RS, White ZS, Visnegarwala
F, Lewis DE, Butel JS.

Epstein-Barr virus DNA loads in adult human immunodeficiency virus type
1-infected patients receiving highly active antiretroviral therapy.
Clin Infect Dis. 2003 Nov 1;37(9):1244-9. Epub 2003 Sep 23.
(PI: J.S. Butel/Biomedical Research and Countermeasures)

4
Berkowitz DE, White R, Li D, Minhas KM, Cernetich A, Kim S, Burke S, Shoukas
AA, Nyhan D, Champion HC, Hare JM.

Arginase reciprocally regulates nitric oxide synthase activity and contributes
to endothelial dysfunction in aging blood vessels.
Circulation. 2003 Oct 21;108(16):2000-6. Epub 2003 Sep 29.
(PI: A.A. Shoukas/Biomedical Research and Countermeasures)

5
Kourentzi KD, Fox GE, Willson RC.
Hybridization-responsive fluorescent DNA probes containing the adenine analog
2-aminopurine.
Anal Biochem. 2003 Nov 1;322(1):124-6.
(PI: G.E. Fox/Biomedical Research and Countermeasures)

6
Saidel GM, DeBella JA 2nd, Cabrera ME.
Metabolic system dynamics: lumped and distributed models.
In: Simulations in biomedicine V. 5th International Conference on Computer
Simulations in Biomedicine, April 2003, Ljubljana, Slovenia.
Ashurst, Southampton, UK: WIT Press ; Billerica, MA: Computational Mechanics,
c2003. p. 101-110 : ill.
(PI: M.E. Cabrera/Biomedical Research and Countermeasures)
LOCATORplus ID: 101199064

7

Note (#7)

Hypergravity results were compared with previous space flight results, leading to the conclusion that gravity acts as a continuum in this system.

Plaut K, Maple RL, Wade CE, Baer LA, Ronca AE.
Effects of hypergravity on mammary metabolic function: gravity acts as a continuum.
J Appl Physiol. 2003 Dec;95(6):2350-4. Epub 2003 Aug 15.
(PIs: C.E. Wade and A.E. Ronca/Fundamental Space Biology)

8
Hwang J, Saha A, Boo YC, Sorescu GP, McNally JS, Holland SM, Dikalov S,
Giddens DP, Griendling KK, Harrison DG, Jo H.

Oscillatory shear stress stimulates endothelial production of O2- from
p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.
J Biol Chem. 2003 Nov 21;278(47):47291-8. Epub 2003 Sep 04.
(PI: H. Jo/Fundamental Space Biology)

9
Wang R, Scharenbroich L, Hart C, Wold B, Mjolsness E.
Clustering analysis of microarray gene expression data by splitting algorithm.
J Parallel Distrib Comput. 2003 Jul-Aug;63(7-8):692-706.
(PI: B. Wold/Fundamental Space Biology)

10
Ligler FS, Taitt CR, Shriver-Lake LC, Sapsford KE, Shubin Y, Golden JP.
Array biosensor for detection of toxins.
Anal Bioanal Chem. 2003 Oct;377(3):469-77. Epub 2003 Jun 13. Review.
(PI: F.S. Ligler/Advanced Human Support Technology)

11
McGilloway RL, Weaver RW, Ming DW, Gruener JE.
Nitrification in a zeoponic substrate.
Plant Soil. 2003 Oct;256(2):371-8.
(PIs: R.L. McGilloway, Graduate Student Researchers Program and D.W. Ming/Advanced Human Support Technology)

12
De Graaff JC, Ubbink DT, Lagarde SM, Jacobs MJ.
Postural changes in capillary pressure in the hallux of healthy volunteers.
J Appl Physiol. 2003 Dec;95(6):2223-8. Epub 2003 Jul 18.

13
Stelzer JE, Widrick JJ.
Effect of hindlimb suspension on the functional properties of slow and fast
soleus fibers from three strains of mice.
J Appl Physiol. 2003 Dec;95(6):2425-33. Epub 2003 Aug 29.

14

Note (#14)

STS-108 results

Harrison BC, Allen DL, Girten B, Stodieck LS, Kostenuik PJ, Bateman TA,
Morony S, Lacey D, Leinwand LA.

Skeletal muscle adaptations to microgravity exposure in the mouse.
J Appl Physiol. 2003 Dec;95(6):2462-70. Epub 2003 Jul 25.

15

Note (#15)

STS-95 results

Hoson T, Soga K, Wakabayashi K, Kamisaka S, Tanimoto E.
Growth and cell wall changes in rice roots during spaceflight.
Plant Soil. 2003 Aug;255(1):19-26.

16
Driss-Ecole D, Lefranc A, Perbal G.
A polarized cell: the root statocyte.
Physiol Plant. 2003 Jul;118(3):305-12.

17
Nakamura Y, Wakabayashi K, Hoson T.
Temperature modulates the cell wall mechanical properties of rice coleoptiles
by altering the molecular mass of hemicellulosic polysaccharides.
Physiol Plant. 2003 Aug;118(4):597-604.

18
Kamada M, Yamasaki S, Fujii N, Higashitani A, Takahashi H.
Gravity-induced modification of auxin transport and distribution for peg
formation in cucumber seedlings: possible roles for CS-AUX1 and CS-PIN1.
Planta. 2003 Nov;218(1):15-26. Epub 2003 Aug 07.

19
Skrobanek P, Hrancova M.
Adaptability of Japanese quail chicks to conditions of simulated
weightlessness.
Acta Vet Brno. 2003 Sep;72(3):347-51.

20

Note (#20)

Researchers predict, based on theoretical considerations, that the transducer in fracture-induced bone remodelling is not osteocytes or their processes per se but rather it is osteocyte processes spanning the crack being cut by shearing motions between the crack faces.

Taylor D, Hazenberg JG, Lee TC.
The cellular transducer in damage-stimulated bone remodelling: a theoretical investigation using fracture mechanics.
J Theor Biol. 2003 Nov 7;225(1):65-75.

21
Kaciuba-Uscilko H, Smorawinski J, Nazar K, Adrian J, Greenleaf JE.
Catecholamine responses to environmental stressors in trained and untrained men after 3-day bed rest.
Aviat Space Environ Med. 2003 Sep;74(9):928-36.

22
Nicholas JS, Butler GC, Davis S, Bryant E, Hoel DG, Mohr LC Jr.
Stable chromosome aberrations and ionizing radiation in airline pilots.
Aviat Space Environ Med. 2003 Sep;74(9):953-6.

23
Yen Pik Sang FD, Golding JF, Gresty MA.
Suppression of sickness by controlled breathing during mildly nauseogenic
motion.
Aviat Space Environ Med. 2003 Sep;74(9):998-1002.

24

Note (#24)

NASA LEDs used.

Sommer AP, Oron U, Pretorius AM, McKay DS, Ciftcioglu N, Mester AR,
Kajander EO, Whelan HT.

A preliminary investigation into light-modulated replication of nanobacteria
and heart disease.
J Clin Laser Med Surg. 2003 Aug;21(4):231-5.

25
Husse B, Sopart A, Isenberg G.
Cyclical mechanical stretch-induced apoptosis in myocytes from young rats but
necrosis in myocytes from old rats.
Am J Physiol Heart Circ Physiol. 2003 Oct;285(4):H1521-7. Epub 2003 Jun 12.

26
Rizzo V, Morton C, DePaola N, Schnitzer JE, Davies PF.
Recruitment of endothelial caveolae into mechanotransduction pathways by flow
conditioning in vitro.
Am J Physiol Heart Circ Physiol. 2003 Oct;285(4):H1720-9. Epub 2003 Jun 19.

27
Reisz-Porszasz S, Bhasin S, Artaza JN, Shen R, Sinha-Hikim I, Hogue A,
Fielder TJ, Gonzalez-Cadavid NF.

Lower skeletal muscle mass in male transgenic mice with muscle-specific
overexpression of myostatin.
Am J Physiol Endocrinol Metab. 2003 Oct;285(4):E876-88. Epub 2003 Jun 24.

28
Hinkle RT, Donnelly E, Cody DB, Samuelsson S, Lange JS, Bauer MB,
Tarnopolsky M, Sheldon RJ, Coste SC, Tobar E, Stenzel-Poore MP, Isfort RJ.

Activation of the CRF 2 receptor modulates skeletal muscle mass under
physiological and pathological conditions.
Am J Physiol Endocrinol Metab. 2003 Oct;285(4):E889-98.

29
The New Face of Space: selected proceedings of the 53rd International
Astronautical Federation Congress, Houston, Texas, USA, 10 October-19 October
2002.
Acta Astronaut. 2003 Aug-Nov;53(4-10):237-846.
View PubMed page

30
McPhee JC, White RJ.
Physiology, medicine, long-duration space flight and the NSBRI.
Acta Astronaut. 2003 Aug-Nov;53(4-10):239-48.

31
Tikhomirov AA, Ushakova SA, Manukovsky NS, Lisovsky GM, Kudenko YA, Koyalev
VS, Gribovskaya IV, Tirrannen LS, Zolotukhin IG, Gros JB, Lasseur C.

Synthesis of biomass and utilization of plants wastes in a physical model of
biological life-support system.
Acta Astronaut. 2003 Aug-Nov;53(4-10):249-57.

32
Leon GR, Sandal GM.
Women and couples in isolated extreme environments: applications for
long-duration missions.
Acta Astronaut. 2003 Aug-Nov;53(4-10):259-67.

33
Kozlovskaya IB, Egorov AD.
Some approaches to medical support for Martian expedition.
Acta Astronaut. 2003 Aug-Nov;53(4-10):269-75.

34
Bushnell GS, Fialho IJ, McDavid T, Allen JL, Quraishi N.
Ground and on-orbit command and data handling architectures for the Active Rack
Isolation System microgravity flight experiment.
Acta Astronaut. 2003 Aug-Nov;53(4-10):309-16.

35
Trinh EH.
Physical sciences research plans for the International Space Station.
Acta Astronaut. 2003 Aug-Nov;53(4-10):317-27.

36
Cooke DR, Joosten BJ, Lo MW, Ford KM, Hansen RJ.
Innovations in mission architectures for exploration beyond low Earth orbit.
Acta Astronaut. 2003 Aug-Nov;53(4-10):387-97.

37
Hofmann P, von Richter A.
Automation and Robotics for Human Mars Exploration (AROMA).
Acta Astronaut. 2003 Aug-Nov;53(4-10):399-404.

38
Belingheri M, Mirra C.
The challenges and opportunities of a commercial human spaceflight mission to
the ISS.
Acta Astronaut. 2003 Aug-Nov;53(4-10):651-7.

39
Kicza M, Erickson K, Trinh E.
Research priorities and plans for the International Space Station--results of
the 'REMAP' Task Force.
Acta Astronaut. 2003 Aug-Nov;53(4-10):659-63.

40

Note (#40)

Overview of ISS research activities through Expedition 5, including a list of investigations.

Roe LB, Uri JJ.
Research progress and accomplishments on International Space Station.
Acta Astronaut. 2003 Aug-Nov;53(4-10):665-80.

41
Launius RD.
Evolving public perceptions of spaceflight in American culture.
Acta Astronaut. 2003 Aug-Nov;53(4-10):823-31.

// end //

More status reports and news releases or top stories.

Please follow SpaceRef on Twitter and Like us on Facebook.

SpaceRef Newsletter