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NASA Spaceline 11 March 2005 Current Awareness

Status Report From: Spaceline
Posted: Friday, March 11, 2005

PubMed's abstract is linked when available and each will open in a new window.

  1. Riley DA, Bain JL, Romatowski JG, Fitts RH. Skeletal muscle fiber atrophy: altered thin filament density changes slow fiber force and shortening velocity. Am J Physiol Cell Physiol. 2005 Feb;288(2):C360-5. Epub 2004 Oct 06. (PI: R.H. Fitts)
  2. Wade CE, Stanford KI, Stein TP, Greenleaf JE. Intensive exercise training suppresses testosterone during bed rest. J Appl Physiol. 2005 Feb 10; [Epub ahead of print] (PIs: C.E. Wade, T.P. Stein, and J.E. Greenleaf)
  3. Wan XS, Zhou Z, Ware JH, Kennedy AR. Standardization of a fluorometric assay for measuring oxidative stress in irradiated cells. Radiat Res. 2005 Feb;163(2):232-40. (PI: A.R. Kennedy)
  4. Kondrashov V, Rothenberg SJ, Chettle D, Zerwekh J. Evaluation of potentially significant increase of lead in the blood during long-term bed rest and space flight. Physiol Meas. 2005 Feb;26(1):1-12. (PI: J. Zerwekh)
  5. Pardo SJ, Patel MJ, Sykes MC, Platt MO, Boyd NL, Sorescu GP, Xu M, van Loon JJ, Wang MD, Jo H. Simulated microgravity using the Random Positioning Machine inhibits differentiation and alters gene expression profiles of 2T3 pre-osteoblasts. Am J Physiol Cell Physiol. 2005 Feb 2; [Epub ahead of print] (PI: H. Jo)
  6. Wang N, Suo Z. Long-distance propagation of forces in a cell. Biochem Biophys Res Commun. 2005 Mar 25;328(4):1133-8. (PI: N. Wang)
  7. Alenghat FJ, Nauli SM, Kolb R, Zhou J, Ingber DE. Global cytoskeletal control of mechanotransduction in kidney epithelial cells. Exp Cell Res. 2004 Nov 15;301(1):23-30. (PI: D.E. Ingber)
  8. Stolc V, Samanta MP, Tongprasit W, Marshall WF. Genome-wide transcriptional analysis of flagellar regeneration in Chlamydomonas reinhardtii identifies orthologs of ciliary disease genes. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3703-7. Epub 2005 Feb 28. (PI: V. Stolc)
  9. Xie Y, Wang Y, Sun T, Wang F, Trostinskaia A, Puscheck E, Rappolee DA. Six post-implantation lethal knockouts of genes for lipophilic MAPK pathway proteins are expressed in preimplantation mouse embryos and trophoblast stem cells. Mol Reprod Dev. 2005 May;71(1):1-11. (PI: D.A. Rappolee)
  10. Correll MJ, Kiss JZ. The roles of phytochromes in elongation and gravitropism of roots. Plant Cell Physiol. 2005 Feb 2; [Epub ahead of print] (PI: J.Z. Kiss) Cover imageNote #10 This image was selected for the cover of Plant & Cell Physiology when the paper was published in print format.
  11. Jiao S, Hilaire E, Guikema JA. Identification and differential accumulation of two isoforms of the CF1-beta subunit under high light stress in Brassica rapa. Plant Physiol Biochem. 2004 Dec;42(11):883-90. Epub 2004 Dec 16. (PI: J.A. Guikema)
  12. Cameron DF, Hushen JJ, Colina L, Mallery J, Willing A, Sanberg PR, Saporta S. Formation and structure of transplantable tissue constructs generated in simulated microgravity from sertoli cells and neuron precursors. Cell Transplant. 2004;13(7-8):755-63. (PIs: D.F. Cameron and S. Saporta) Note #12 Microgravity simulated by bioreactor.

Other papers of interest:

  1. Ciftcioglu N, Haddad RS, Golden DC, Morrison DR, McKay DS. A potential cause for kidney stone formation during space flights: enhanced growth of nanobacteria in microgravity. Kidney Int. 2005 Feb;67(2):483-91. Note A Microgravity simulated by bioreactor.
  2. Groppo ER, Eastlack RK, Mahar A, Hargens AR, Pedowitz RA. Simulated hypergravity running increases skeletal and cardiovascular loads. Med Sci Sports Exerc. 2005 Feb;37(2):262-6.
  3. Sage C, Huang M, Karimi K, Gutierrez G, Vollrath MA, Zhang DS, Garcia-Anoveros J, Hinds PW, Corwin JT, Corey DP, Chen ZY. Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. Science. 2005 Feb 18;307(5712):1114-8. Epub 2005 Jan 13. Note C From abstract: "Manipulation of the pRb pathway may ultimately lead to mammalian hair cell regeneration."
  4. Desaphy JF, Pierno S, Liantonio A, De Luca A, Didonna MP, Frigeri A, Nicchia GP, Svelto M, Camerino C, Zallone A, Camerino DC. Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile. Neurobiol Dis. 2005 Mar;18(2):356-65.
  5. Fu ZJ, Zhang LF, Ma J, Cheng HW. [Changes in voltage-dependent calcium channel currents of vascular smooth muscle cells isolated from small mesenteric arteries of simulated weightless rats.] Sheng Li Xue Bao. 2005 Feb 25;57(1):27-32. Chinese.
  6. Sekulic SR, Lukac DD, Naumovic NM. The fetus cannot exercise like an astronaut: gravity loading is necessary for the physiological development during second half of pregnancy. Med Hypotheses. 2005;64(2):221-8.
  7. Babich A. Tumor necrosis by controlled ebullism. Med Hypotheses. 2005;64(2):318-9. Note G Drawing upon experiments conducted during the early days of manned space flight in which animals were exposed to a near vacuum, the author proposes destroying tumors by boiling of localized body fluids under reduced pressure.

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