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NASA Spaceline 22 July 2005 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Friday, July 22, 2005

PubMed's abstract is linked when available and each will open in a new window.

  1. Koh TJ, Bryer SC, Pucci AM, Sisson TH. Mice deficient in plasminogen activator inhibitor-1 have improved skeletal muscle regeneration. Am J Physiol Cell Physiol. 2005 Jul;289(1):C217-23. Epub 2005 Feb 16. (HSR&T PI: S.C. Bryer, NASA Graduate Student Researcher Program) Note (#1) From abstract: "Taken together, these results indicate that PAI-1 deficiency promotes muscle regeneration, and this protease inhibitor represents a therapeutic target for enhancing muscle regeneration."
  2. Stein TP, Wade CE. Metabolic consequences of muscle disuse atrophy. J Nutr. 2005 Jul;135(7):1824S-8S. (HSR&T PIs: T.P. Stein, C.E. Wade)
  3. Krauzlis RJ. The control of voluntary eye movements: new perspectives. Neuroscientist. 2005 Apr;11(2):124-37. Review. (HSR&T PI: R.J. Krauzlis)
  4. Ingber DE. Tissue adaptation to mechanical forces in healthy, injured and aging tissues. Scand J Med Sci Sports. 2005 Aug;15(4):199-201. (HSR&T PI: D.E. Ingber)
  5. Cui C, Yang X, Chuai M, Glazier JA, Weijer CJ. Analysis of tissue flow patterns during primitive streak formation in the chick embryo. Dev Biol. 2005 Jun 8; [Epub ahead of print] (HSR&T PI: J.A. Glazier)
  6. Venken KJ, Bellen HJ. Emerging technologies for gene manipulation in Drosophila melanogaster. Nat Rev Genet. 2005 Mar;6(3):167-78. Review. Erratum in: Nat Rev Genet. 2005 Apr;6(4):340. (HSR&T PI: H.J. Bellen)
  7. Baker PW, Leff LG. Attachment to stainless steel by Mir Space Station bacteria growing under modeled reduced gravity at varying nutrient concentrations. Biofilms. 2005 Jan;2(1):1-7. (HSR&T PI: L.G. Leff) Note (#7) Bacteria recovered from Mir grown on bioreactors.
  8. Yoon Y, Lueptow RM. Reverse osmosis membrane rejection for ersatz space mission wastewaters. Water Res. 2005 Jul 5; [Epub ahead of print] (HSR&T PI: R.M. Lueptow)
  9. Petculescu AG, Lueptow RM. Fine-tuning molecular acoustic models: sensitivity of the predicted attenuation to the Lennard-Jones parameters. J Acoust Soc Am. 2005 Jan;117(1):175-84. (HSR&T PI: R.M. Lueptow)
  10. Kitmacher GH, Gerstenmaier WH, Bartoe JD, Mustachio N. The International Space Station: a pathway to the future. Acta Astronaut. 2005 Jul-Oct;57(2-8):594-603.
  11. Ritsher JB, Ihle EC, Kanas N. Positive psychological effects of space missions. Acta Astronaut. 2005 Jul-Oct;57(2-8):630-3. (HSR&T PI: N. Kanas)
  12. Sandal GM, Musson D, Helmreich RL, Gravdal L. Social desirability bias in personality testing: implications for astronaut selection. Acta Astronaut. 2005 Jul-Oct;57(2-8):634-41. (HSR&T PI: R.L. Helmreich)
  13. Hubbard GS. Humans and robots: hand in grip. Acta Astronaut. 2005 Jul-Oct;57(2-8):649-60.
  14. Mendell WW. Meditations on the new space vision: the Moon as a stepping stone to Mars. Acta Astronaut. 2005 Jul-Oct;57(2-8):676-83.

Other papers of interest:

  1. Morbidelli L, Monici M, Marziliano N, Cogoli A, Fusi F, Waltenberger J, Ziche M. Simulated hypogravity impairs the angiogenic response of endothelium by up-regulating apoptotic signals. Biochem Biophys Res Commun. 2005 Jul 7; [Epub ahead of print] Note A Hypogravity simulated by rotating random positioning machine.
  2. Gulli G, Cooper VL, Claydon VE, Hainsworth R. Prolonged latency in the baroreflex mediated vascular resistance response in subjects with postural related syncope. Clin Auton Res. 2005 Jun;15(3):207-12.
  3. Cavagna GA, Heglund NC, Willems PA. Effect of an increase in gravity on the power output and the rebound of the body in human running. J Exp Biol. 2005 Jun;208(Pt 12):2333-46. Note C Parabolic flights were used to assess the effect of an increase in gravity.
  4. Basso N, Jia Y, Bellows CG, Heersche JN. The effect of reloading on bone volume, osteoblast number, and osteoprogenitor characteristics: studies in hind limb unloaded rats. Bone. 2005 Jul 7; [Epub ahead of print]
  5. Kondo H, Nifuji A, Takeda S, Ezura Y, Rittling S, Denhardt DT, Nakashima K, Karsenty G, Noda M. Unloading induces osteoblastic cell suppression and osteoclastic cell activation to lead to bone loss via sympathetic nervous system. J Biol Chem. 2005 Jun 16; [Epub ahead of print] Note E Unloading was induced by a variant of the hindlimb unloading technique: tape was applied to the surface of the mouse hind limb to set a metal clip that was fixed to an overhead bar. This paper currently can be obtained online at no charge.
  6. Konhilas JP, Widegren U, Allen DL, Paul AC, Cleary A, Leinwand LA. Loaded wheel running and muscle adaptation in the mouse. Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H455-65. Epub 2005 Feb 25.
  7. Israel I, Crockett M, Zupan L, Merfeld D. Reproduction of ON-center and OFF-center self-rotations. Exp Brain Res. 2005 Jun;163(4):540-6. Epub 2005 Jun 4.
  8. Buravkova L, Romanov Yu, Rykova M, Grigorieva O, Merzlikina N. Cell-to-cell interactions in changed gravity: ground-based and flight experiments. Acta Astronaut. 2005 Jul-Oct;57(2-8):67-74. Note H Includes ISS results.
  9. Iwase S. Effectiveness of centrifuge-induced artificial gravity with ergometric exercise as a countermeasure during simulated microgravity exposure in humans. Acta Astronaut. 2005 Jul-Oct;57(2-8):75-80.
  10. Fjallman T, Hall JC. Antibody engineering--a valuable asset in preventing closed environment epidemics. Acta Astronaut. 2005 Jul-Oct;57(2-8):81-8.

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