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NASA Spaceline 9 December 2005 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Friday, December 9, 2005

PubMed's abstract is linked when available and each will open in a new window.

  1. Xiao X, Grenon SM, Kim C, Sheynberg N, Hurwitz S, Williams GH, Cohen RJ. Bed rest effects on human calf hemodynamics and orthostatic intolerance: a model-based analysis. Aviat Space Environ Med. 2005 Nov;76(11):1037-45. (HSR&T PIs: G.H. Williams, R.J. Cohen))
  2. Hinghofer-Szalkay HG, Rossler A, Evans JM, Stenger MB, Moore FB, Knapp CF. Circulatory galanin levels increase several fold with intense orthostatic challenge in healthy humans. J Appl Physiol. 2005 Dec 1; [Epub ahead of print] Note: ARC's Human Powered Centrifuge was used in the study.
  3. Brown M, Foley A, Ferreria JA. Ovariectomy, hindlimb unweighting, and recovery effects on skeletal muscle in adult rats. Aviat Space Environ Med. 2005 Nov;76(11):1012-8.
  4. Kandarian SC, Jackman RW. Intracellular signaling during skeletal muscle atrophy. Muscle Nerve. 2005 Oct 14; [Epub ahead of print] (HSR&T PI: S.C. Kandarian)
  5. Behnke BJ, Padilla D, Ferreira LF, Delp MD, Musch TI, Poole DC. Effects of arterial hypotension on microvascular oxygen exchange in contracting skeletal muscle. J Appl Physiol. 2005 Nov 10; [Epub ahead of print] (HSR&T PI: M.D. Delp)
  6. Zayzafoon M, Meyers VE, McDonald JM. Microgravity: the immune response and bone. Immunol Rev. 2005 Dec;208:267-80. (HSR&T PI: J.M.McDonald)
  7. Riddle RC, Taylor AF, Genetos DC, Donahue HJ. MAP kinase and calcium signaling mediate fluid flow-induced human mesenchymal stem cell proliferation. Am J Physiol Cell Physiol. 2005 Nov 2; [Epub ahead of print] (HSR&T PI: D.C. Genetos, NASA Graduate Student Researcher Program)
  8. Heiser LM, Colby CL. Spatial updating in area LIP is independent of saccade direction. J Neurophysiol. 2005 Nov 16; [Epub ahead of print] (HSR&T PI: L. Heiser, NASA Graduate Student Researcher Program)
  9. Lele TP, Pendse J, Kumar S, Salanga M, Karavitis J, Ingber DE. Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells. J Cell Physiol. 2005 Nov 15; [Epub ahead of print] (HSR&T PI: D.E. Ingber) Note: From abstract: "These findings demonstrate that the molecular binding kinetics of some, but not all, focal adhesion proteins are sensitive to mechanical force?" Zyxin was found to be sensitive; vinculin was not.

Other papers of interest:

  1. Voustianiouk A, Kaufmann H, Diedrich A, Raphan T, Biaggioni I, Macdougall H, Ogorodnikov D, Cohen B. Electrical activation of the human vestibulo-sympathetic reflex. Exp Brain Res. 2005 Nov 25;:1-11 [Epub ahead of print]
  2. Popovic ZB, Prasad A, Garcia MJ, Arbab-Zadeh A, Borowski A, Dijk E, Greenberg NL, Levine BD, Thomas JD. Relationship between diastolic intraventricular pressure gradients, relaxation, and preload: impact of age and fitness. Am J Physiol Heart Circ Physiol. 2005 Nov 11; [Epub ahead of print]
  3. Usov AI, Vasiagina TI, Stel'nikova IG. [Complex morpho-functional characteristic of adrenal medulla and cardiac sino-auricular area in dogs after 30 day hypokinesia] Morfologiia. 2005;127(2):47-51. Russian.
  4. Aguila HL, Rowe DW. Skeletal development, bone remodeling, and hematopoiesis. Immunol Rev. 2005 Dec;208:7-18.
  5. Mi LY, Fritton SP, Basu M, Cowin SC. Analysis of avian bone response to mechanical loading-Part One: Distribution of bone fluid shear stress induced by bending and axial loading. Biomech Model Mechanobiol. 2005 Oct 25; [Epub ahead of print]
  6. Xie D, Cheng H, Hamrick M, Zhong Q, Ding KH, Correa D, Williams S, Mulloy A, Bollag W, Bollag RJ, Runner RR, McPherson JC, Insogna K, Isales CM. Glucose-dependent insulinotropic polypeptide receptor knockout mice have altered bone turnover. Bone. 2005 Oct 7; [Epub ahead of print]
  7. Caruso JF, Herron JC, Hernandez DA, Porter A, Schweickert T, Manning TF. Metabolic responses to the seated calf press exercise performed against inertial resistance. Aviat Space Environ Med. 2005 Nov;76(11):1019-23. Note: The paper describes applicability of this research to the flywheel exercise device said to be scheduled for use on ISS.
  8. Klosterhalfen S, Kellermann S, Pan F, Stockhorst U, Hall G, Enck P. Effects of ethnicity and gender on motion sickness susceptibility. Aviat Space Environ Med. 2005 Nov;76(11):1051-7.
  9. Bryce LM, Butler WP, Pilmanis AA, King H. Headache and altitude decompression sickness: joint pain or neurological pain? Aviat Space Environ Med. 2005 Nov;76(11):1074-8.
  10. Tafforin C. Ethological indicators of isolated and confined teams in the perspective of missions to Mars. Aviat Space Environ Med. 2005 Nov;76(11):1083-7.
  11. Gandia P, Saivin S, Houin G. The influence of weightlessness on pharmacokinetics. Fundam Clin Pharmacol. 2005 Dec;19(6):625-36.
  12. Maurer C, Mergner T, Peterka RJ. Multisensory control of human upright stance. Exp Brain Res. 2005 Nov 24;:1-20 [Epub ahead of print]
  13. Kasahara S, Akao T, Fukushima J, Kurkin S, Fukushima K. Further evidence for selective difficulty of upward eye pursuit in juvenile monkeys: effects of optokinetic stimulation, static roll tilt, and active head movements. Exp Brain Res. 2005 Nov 30;:1-16 [Epub ahead of print]
  14. Luebke AE, Maroni PD, Guth SM, Lysakowski A. Alpha-9 nicotinic acetylcholine receptor immunoreactivity in the rodent vestibular labyrinth. J Comp Neurol. 2005 Nov 21;492(3):323-33.
  15. Cotrupi S, Ranzani D, Maier JA. Impact of modeled microgravity on microvascular endothelial cells. Biochim Biophys Acta. 2005 Nov 2; [Epub ahead of print] Note: Used rotating wall vessel bioreactor.
  16. Carvalho HM, Teel LD, Goping G, O'brien AD. A three-dimensional tissue culture model for the study of attach and efface lesion formation by enteropathogenic and enterohaemorrhagic Escherichia coli. Cell Microbiol. 2005 Dec;7(12):1771-81. Note: Used rotary cell culture system. This paper can be obtained online without charge.

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