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NASA Spaceline 6 January 2006 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Friday, January 6, 2006

PubMed's abstract is linked when available and each will open in a new window.

  1. Szewczyk NJ, Mancinelli RL, McLamb W, Reed D, Blumberg BS, Conley CA. Caenorhabditis elegans survives atmospheric breakup of STS-107, Space Shuttle Columbia. Astrobiology. 2005 Dec;5(6):690-705. (HSR&T PI: C.A. Conley) Note: STS-107 results. An image from this paper, which can be obtained online without charge, appears on the cover of this issue of the journal (http://www.liebertonline.com/ast)
  2. Haddad F, Adams GR. Aging sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophy. J Appl Physiol. 2005 Dec 22; [Epub ahead of print] (HSR&T PI: K.M. Baldwin)
  3. Rubin J, Rubin C, Jacobs CR. Molecular pathways mediating mechanical signaling in bone. Gene. 2005 Dec 14; [Epub ahead of print] (HSR&T PIs: C. Rubin, C.R. Jacobs)
  4. Stains JP, Civitelli R. Gap junctions in skeletal development and function. Biochim Biophys Acta. 2005 Dec 20;1719(1-2):69-81. Epub 2005 Nov 14. (HSR&T PI: R. Civitelli)
  5. Bayorh MA, Ganafa AA, Eatman D, Walton M, Feuerstein GZ. Simvastatin and losartan enhance nitric oxide and reduce oxidative stress in salt-induced hypertension. Am J Hypertens. 2005 Nov;18(11):1496-502.
  6. Townsend LW. Implications of the space radiation environment for human exploration in deep space. Radiat Prot Dosimetry. 2005;115(1-4):44-50. (HSR&T PI: L.W. Townsend) Note: This paper and four papers in the ?Other? section are from an issue of this journal containing numerous papers deriving from the Tenth International Conference on Radiation Shielding (ICRS-10) and the Topical Meeting on Radiation Protection and Shielding (RPS 2004) of the American Nuclear Society, held in Portugual in May 2004.
  7. Laud PR, Multani AS, Bailey SM, Wu L, Ma J, Kingsley C, Lebel M, Pathak S, DePinho RA, Chang S. Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway. Genes Dev. 2005 Nov 1;19(21):2560-70. (HSR&T PI: S.M. Bailey)
  8. Sakamoto K, Liu C, Kasamatsu M, Pozdeyev NV, Iuvone PM, Tosini G. Dopamine regulates melanopsin mRNA expression in intrinsically photosensitive retinal ganglion cells. Eur J Neurosci. 2005 Dec;22(12):3129-36. (HSR&T PI: G. Tosini)
  9. Itle LJ, Pishko MV. Multiphenotypic whole-cell sensor for viability screening. Anal Chem. 2005 Dec 15;77(24):7887-93. (HSR&T PI: M.V. Pishko)
  10. Ritz BW, Lelkes PI, Gardner EM. Functional recovery of peripheral blood mononuclear cells in modeled microgravity. FASEB J. 2005 Dec 21; [Epub ahead of print] (HSR&T PI: P.I. Lelkes) Note: Used high aspect ratio vessel (HARV) bioreactor.
  11. Krumenacker JS, Murad F. NO-cGMP signaling in development and stem cells. Mol Genet Metab. 2005 Dec 12; [Epub ahead of print] (HSR&T PI: F. Murad)
  12. Ma Z, Hasenstein KH. The onset of gravisensitivity in the embryonic root of flax. Plant Physiol. 2005 Dec 23; [Epub ahead of print] (HSR&T PI: K.H. Hasenstein) Note: This paper can be obtained online without charge.

Other papers of interest:

  1. Novikova N, De Boever P, Poddubko S, Deshevaya E, Polikarpov N, Rakova N, Coninx I, Mergeay M. Survey of environmental biocontamination on board the International Space Station. Res Microbiol. 2005 Dec 1; [Epub ahead of print] Note: ISS results.
  2. Cieniewski-Bernard C, Mounier Y, Michalski JC, Bastide B. O-GlcNAc level variations are associated with the development of skeletal muscle atrophy. J Appl Physiol. 2005 Dec 15; [Epub ahead of print] Note: Hindlimb unloading was used.
  3. Deschenes MR, Tenny KA, Wilson MH. Increased and decreased activity elicits specific morphological adaptations of the neuromuscular junction. Neuroscience. 2005 Dec 13; [Epub ahead of print] Note: Hindlimb unloading was used.
  4. Nanke Y, Kotake S, Ninomiya T, Furuya T, Ozawa H, Kamatani N. Geranylgeranylacetone inhibits formation and function of human osteoclasts and prevents bone loss in tail-suspended rats and ovariectomized rats. Calcif Tissue Int. 2005 Dec;77(6):376-385. Epub 2005 Dec 8.
  5. Monici M, Fusi F, Paglierani M, Marziliano N, Cogoli A, Pratesi R, Bernabei PA. Modeled gravitational unloading triggers differentiation and apoptosis in preosteoclastic cells. J Cell Biochem. 2005 Dec 19; [Epub ahead of print] Note: Used random positioning machine to simulate gravitational unloading.
  6. No authors listed. [The dynamic of breathing biomechanics and intrathoracic hemodynamics parameters during microgravity modeling] Ross Fiziol Zh Im I M Sechenova. 2005 Sep;91(9):1091-6. Russian. Note: Used supine and head-down tilt positions in cats to model microgravity.
  7. Robertson D, Garland EM, Raj SR, Demartinis N. Case report: Marathon runner with severe autonomic failure. Lancet. 2005 Dec;366 Suppl 1:S13. No abstract available. Note: A woman with a history of orthostatic and exercise intolerance (unable to stand more than two minutes) and treated for dopamine beta-hydroxylase deficiency was able to successfully complete a marathon.
  8. Reid GM. Sudden infant death syndrome (SIDS): microgravity and inadequate sensory stimulation. Med Hypotheses. 2005 Dec 22; [Epub ahead of print]
  9. Miyoshi T, Hotta K, Yamamoto SI, Nakazawa K, Akai M. Somatosensory graviception inhibits soleus H-reflex gain in humans during walking. Exp Brain Res. 2005 Dec 20;:1-4 [Epub ahead of print] Note: This paper can currently be obtained online without charge.
  10. Tanaka K, Gotoh TM, Awazu C, Morita H. Roles of the vestibular system in controlling arterial pressure in conscious rats during a short period of microgravity. Neurosci Lett. 2005 Dec 26; [Epub ahead of print] Note: Microgravity was induced by free drop, performed at the Microgravity Laboratory of Japan.
  11. Leonard BE. The radon inverse dose rate effect and high-LET galactic hazards. Radiat Prot Dosimetry. 2005;115(1-4):310-5.
  12. Leonard A, Rueff J, Gerber GB, Leonard ED. Usefulness and limits of biological dosimetry based on cytogenetic methods. Radiat Prot Dosimetry. 2005;115(1-4):448-54.
  13. Rodrigues AS, Oliveira NG, Gil OM, Leonard A, Rueff J. Use of cytogenetic indicators in radiobiology. Radiat Prot Dosimetry. 2005;115(1-4):455-60.
  14. Montoro A, Almonacid M, Serrano J, Saiz M, Barquinero JF, Barrios L, Verdu G, Perez J, Villaescusa JI. Assessment by cytogenetic analysis of the radioprotection properties of propolis extract. Radiat Prot Dosimetry. 2005;115(1-4):461-4.
  15. Alon R, Feigelson SW, Manevich E, Rose DM, Schmitz J, Overby DR, Winter E, Grabovsky V, Shinder V, Matthews BD, Sokolovsky-Eisenberg M, Ingber DE, Benoit M, Ginsberg MH. {alpha}4{beta}1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the {alpha}4-cytoplasmic domain. J Cell Biol. 2005 Dec 19;171(6):1073-84.
  16. Esmon CA, Tinsley AG, Ljung K, Sandberg G, Hearne LB, Liscum E. A gradient of auxin and auxin-dependent transcription precedes tropic growth responses. Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):236-41. Epub 2005 Dec 21.
  17. Dai Y, Wang H, Li B, Huang J, Liu X, Zhou Y, Mou Z, Li J. Increased expression of MAP KINASE KINASE7 causes deficiency in polar auxin transport and leads to plant architectural abnormality in Arabidopsis. Plant Cell. 2005 Dec 23; [Epub ahead of print]

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