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NASA Spaceline 19 May 2006 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Friday, May 19, 2006

PubMed's abstract is linked when available and each will open in a new window.

  1. Hamilton DR, Murray JD, Ball CG. Cardiac health for astronauts: coronary calcification scores and CRP as criteria for selection and retention. Aviat Space Environ Med. 2006 Apr;77(4):377-87.
  2. Shebilske WL, Tubre T, Tubre AH, Oman CM, Richards JT. Three-dimensional spatial skill training in a simulated space station: random vs. blocked designs. Aviat Space Environ Med. 2006 Apr;77(4):404-9. (HSR&T PI: C.M. Oman)
  3. Platts SH, Ziegler MG, Waters WW, Meck JV. Hemodynamic effects of midodrine after spaceflight in astronauts without orthostatic hypotension. Aviat Space Environ Med. 2006 Apr;77(4):429-33. (HSR&T PI: J.V. Meck) Note: Shuttle results.
  4. Platts SH, Shi SJ, Meck JV. Akathisia with combined use of midodrine and promethazine. JAMA. 2006 May 3;295(17):2000-1. (HSR&T PI: J.V. Meck)
  5. Zwart SR, Dekerlegand DE, Davis-Street JE, Smith SM. Assessment of urinary N-telopeptide: Point-of-care testing, sample types, and relationship to urinary helical peptide excretion. Clin Chim Acta. 2006 May 4; [Epub ahead of print] (HSR&T PI: S.M. Smith)
  6. Ishihara A, Yamashiro J, Matsumoto A, Higashibata A, Ishioka N, Shimazu T, Ohira Y. Comparison of cell body size and oxidative enzyme activity in motoneurons between the cervical and lumbar segments in the rat spinal cord after spaceflight and recovery. Neurochem Res. 2006 May 4; [Epub ahead of print] Note: STS-40 (SLS-1) results. Biospecimen Sharing Program.
  7. Bailey SM, Murnane JP. Telomeres, chromosome instability and cancer. Nucleic Acids Res. 2006 May 8;34(8):2408-17. Print 2006. (HSR&T PIs: S.M. Bailey, R. Ullrich) Note: This paper can be obtained online without charge.
  8. Ponomarev AL, Cucinotta FA. Chromatin loops are responsible for higher counts of small DNA fragments induced by high-LET radiation, while chromosomal domains do not affect the fragment sizes. Int J Radiat Biol. 2006 Apr;82(4):293-305. (HSR&T PI: F.A. Cucinotta)
  9. Vaughan MB, Ramirez RD, Wright WE, Minna JD, Shay JW. A three-dimensional model of differentiation of immortalized human bronchial epithelial cells. Differentiation. 2006 Apr;74(4):141-8. (HSR&T PI: J.D. Minna)
  10. Lam CW, James JT, McCluskey R, Arepalli S, Hunter RL. A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks. Crit Rev Toxicol. 2006 Mar;36(3):189-217. Note: The first four authors are at, or are affiliated with, NASA JSC.
  11. Moschou EA, Nicholson AD, Jia G, Zoval JV, Madou MJ, Bachas LG, Daunert S. Integration of microcolumns and microfluidic fractionators on multitasking centrifugal microfluidic platforms for the analysis of biomolecules. Anal Bioanal Chem. 2006 May 9; [Epub ahead of print] (HSR&T PI: S. Daunert)
  12. Fritzsch B, Pauley S, Beisel KW. Cells, molecules and morphogenesis: the making of the vertebrate ear. Brain Res. 2006 Apr 25; [Epub ahead of print] (HSR&T PI: B. Fritzsch)
  13. Castro LF, Rasmussen SL, Holland PW, Holland ND, Holland LZ. A Gbx homeobox gene in amphioxus: Insights into ancestry of the ANTP class and evolution of the midbrain/hindbrain boundary. Dev Biol. 2006 May 8; [Epub ahead of print] (HSR&T PI: M. Bronner-Fraser)

Other papers of interest:

  1. John-Baptiste A, Cook T, Straus S, Naglie G, Gray G, Tomlinson G, Krahn M. Decision analysis in aerospace medicine: costs and benefits of a hyperbaric facility in space. Aviat Space Environ Med. 2006 Apr;77(4):434-42; discussion 442-3. Note: An editorial note accompanying this paper praised the author?s use of decision analysis to address a space medicine issue. ?It might at first seem prudent to delay the use of these tools [evidence-based medicine, risk assessment, decision analysis] in space medicine until we achieve a firm base of evidence and experience. However, early application of these techniques allows us to formally assess what we know and do not know, and identify the holes in our knowledge with potentially serious operational consequences.?
  2. Fuglesang C, Narici L, Picozza P, Sannita WG. Phosphenes in low earth orbit: survey responses from 59 astronauts. Aviat Space Environ Med. 2006 Apr;77(4):449-52.
  3. Zhong S, Lowe DA, Thompson LV. Effects of hindlimb unweighting and aging on rat semimembranosus muscle and myosin. J Appl Physiol. 2006 May 11; [Epub ahead of print]
  4. Pozzo M, Alkner B, Norrbrand L, Farina D, Tesch PA. Muscle-fiber conduction velocity during concentric and eccentric actions on a flywheel exercise device. Muscle Nerve. 2006 May 10; [Epub ahead of print]
  5. Cormie P, Deane RS, Triplett NT, McBride JM. Acute effects of whole-body vibration on muscle activity, strength, and power. J Strength Cond Res. 2006 May;20(2):257-61.
  6. Stevens HY, Meays DR, Frangos JA. Pressure gradients and transport in the murine femur upon hindlimb suspension. Bone. 2006 May 2; [Epub ahead of print]
  7. Wang Y, Sakata T, Elalieh HZ, Munson SJ, Burghardt A, Majumdar S, Halloran BP, Bikle DD. Gender differences in the response of CD-1 mouse bone to parathyroid hormone: potential role of IGF-I. J Endocrinol. 2006 May;189(2):279-87.
  8. Dishman RK, Berthoud HR, Booth FW, Cotman CW, Edgerton VR, Fleshner MR, Gandevia SC, Gomez-Pinilla F, Greenwood BN, Hillman CH, Kramer AF, Levin BE, Moran TH, Russo-Neustadt AA, Salamone JD, Van Hoomissen JD, Wade CE, York DA, Zigmond MJ. Neurobiology of exercise. Obesity (Silver Spring). 2006 Mar;14(3):345-56.
  9. Zhou DX, Qiu SD, Wang ZY, Zhang J. [Effect of tail-suspension on the reproduction of adult male rats] Zhonghua Nan Ke Xue. 2006 Apr;12(4):326-9. Chinese.
  10. Yang F, Stenoien DL, Strittmatter EF, Wang J, Ding L, Lipton MS, Monroe ME, Nicora CD, Gristenko MA, Tang K, Fang R, Adkins JN, Camp DG 2nd, Chen DJ, Smith RD. Phosphoproteome profiling of human skin fibroblast cells in response to low- and high-dose irradiation. J Proteome Res. 2006 May;5(5):1252-60.
  11. Choi EK, Ji IM, Lee SR, Kook YH, Griffin RJ, Lim BU, Kim JS, Lee DS, Song CW, Park HJ. Radiosensitization of tumor cells by modulation of ATM kinase. Int J Radiat Biol. 2006 Apr;82(4):277-83.
  12. Cohen B. Inner ear troubles: the roar in the forest? FASEB J. 2006 May;20(7):806-8. Note: This article explains the cause and treatment of benign paroxysmal positional vertigo. The author speculates that some of the roars from the forest in Jurassic Park were actually cries from dinosaurs experiencing BPPV, since the canal/otolith system of dinosaurs was apparently similar to that of humans.
  13. Hood BM, Wilson A, Dyson S. The effect of divided attention on inhibiting the gravity error. Dev Sci. 2006 May;9(3):303-8.
  14. Dharmasiri S, Swarup R, Mockaitis K, Dharmasiri N, Singh SK, Kowalchyk M, Marchant A, Mills S, Sandberg G, Bennett MJ, Estelle M. AXR4 is required for localization of the auxin influx facilitator AUX1. Science. 2006 May 11; [Epub ahead of print]
  15. Wisniewska J, Xu J, Seifertova D, Brewer PB, Ruzicka K, Blilou I, Rouquie D, Benkova E, Scheres B, Friml J. Polar PIN localization directs auxin flow in plants. Science. 2006 May 12;312(5775):883. Epub 2006 Apr 6.
  16. Petrasek J, Mravec J, Bouchard R, Blakeslee JJ, Abas M, Seifertova D, Wisniewska J, Tadele Z, Kubes M, Covanova M, Dhonukshe P, Skupa P, Benkova E, Perry L, Krecek P, Lee OR, Fink GR, Geisler M, Murphy AS, Luschnig C, Zazimalova E, Friml J. PIN proteins perform a rate-limiting function in cellular auxin efflux. Science. 2006 May 12;312(5775):914-8. Epub 2006 Apr 6. Note: In the May 12 issue of Science, T. Sieberer and O. Leyser comment on the above three papers in an article entitled: ?Plant science. Auxin transport, but in which direction?? (PMID 16690849)
  17. Gutjahr C, Nick P. Acrylamide inhibits gravitropism and affects microtubules in rice coleoptiles. Protoplasma. 2006 May 3; [Epub ahead of print]

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