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NASA Spaceline 9 June 2006 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Tuesday, June 27, 2006

PubMed's abstract is linked when available and each will open in a new window.

  1. Liu C, Hadjiargyrou M. Identification and characterization of the Mustang promoter: Regulation by AP-1 during myogenic differentiation. Bone. 2006 May 26; [Epub ahead of print] (HSR&T PI: M. Hadjiargyrou)
  2. Sinha S, Sinha U, Edgerton VR. In vivo diffusion tensor imaging of the human calf muscle. J Magn Reson Imaging. 2006 May 25; [Epub ahead of print] (HSR&T PI: S. Sinha)
  3. Hamilton SA, Pecaut MJ, Gridley DS, Travis ND, Bandstra ER, Willey JS, Nelson G, Bateman TA. A murine model for bone loss from therapeutic and space-relevant sources of radiation. J Appl Physiol. 2006 Jun 1; [Epub ahead of print] (HSR&T PIs: G. Nelson, T.A. Bateman) Note: This paper reports the development of an animal model, which had not previously existed, to study the cause of radiation-induced bone loss. Effects of therapeutic-level and space flight-level radiation on bone loss are reported.
  4. Fuller PM, Fuller CA. Genetic evidence for a neurovestibular influence on the mammalian circadian pacemaker. J Biol Rhythms. 2006 Jun;21(3):177-84. (HSR&T PI: C.A. Fuller) Note: From paper: "In summary, the results of the present study (1) provide the first neurobehavioral evidence for a vestibular-CTS interrelationship, (2) contribute to our understanding of the regulation of the intrinsic circadian period, (3) suggest a novel afferent role for the macular gravity receptors in transducing activitybased nonphotic stimuli, (4) may have important implications for space-bound individuals, and, perhaps most important, (5) have practical implications for understanding the pathophysiology of, and developing treatments for, circadian and circadian sleep-wake disorders with vestibular etiologies."
  5. Tataroglu O, Davidson AJ, Benvenuto LJ, Menaker M. The methamphetamine-sensitive circadian oscillator (MASCO) in mice. J Biol Rhythms. 2006 Jun;21(3):185-94. (HSR&T PI: M. Menaker)
  6. Indic P, Gurdziel K, Kronauer RE, Klerman EB. Development of a two-dimension manifold to represent high dimension mathematical models of the intracellular mammalian circadian clock. J Biol Rhythms. 2006 Jun;21(3):222-32. (HSR&T PI: E.B. Klerman)
  7. Ruthruff E, Van Selst M, Johnston JC, Remington R. How does practice reduce dual-task interference: Integration, automatization, or just stage-shortening? Psychol Res. 2006 Mar;70(2):125-42. Epub 2004 Nov 17.
  8. Johnston JC, McCann RS. On the locus of dual-task interference: Is there a bottleneck at the stimulus classification stage? Q J Exp Psychol (Colchester). 2006 Apr;59(4):694-719.
  9. Honer Zu Bentrup K, Ramamurthy R, Ott CM, Emami K, Nelman-Gonzalez M, Wilson JW, Richter EG, Goodwin TJ, Alexander JS, Pierson DL, Pellis N, Buchanan KL, Nickerson CA. Three-dimensional organotypic models of human colonic epithelium to study the early stages of enteric salmonellosis. Microbes Infect. 2006 Apr 27; [Epub ahead of print] (HSR&T PI: C.A. Nickerson) Note: Used rotating wall vessel bioreactor.
  10. Snell EH, van der Woerd MJ, Damon M, Judge RA, Myles DA, Meilleur F. Optimizing crystal volume for neutron diffraction: D-xylose isomerase. Eur Biophys J. 2006 May 25; [Epub ahead of print] (HSR&T PI: E.H. Snell)

Other papers of interest:

  1. Cermack M. Monitoring and telemedicine support in remote environments and in human space flight. Br J Anaesth. 2006 May 26; [Epub ahead of print]
  2. McInnis NH, Journeay WS, Jay O, Leclair EE, Kenny GP. 15 degrees Head-down tilt attenuates the postexercise reduction in cutaneous vascular conductance and sweating and decreases esophageal temperature recovery time. J Appl Physiol. 2006 Jun 1; [Epub ahead of print]
  3. Suzue N, Nikawa T, Onishi Y, Yamada C, Hirasaka K, Ogawa T, Furochi H, Kosaka H, Ishidoh K, Gu H, Takeda S, Ishimaru N, Hayashi Y, Yamamoto H, Kishi K, Yasui N. Ubiquitin ligase Cbl-b downregulates bone formation through suppression of IGF-I signaling in osteoblasts during denervation. J Bone Miner Res. 2006 May;21(5):722-34.
  4. Winslow MM, Pan M, Starbuck M, Gallo EM, Deng L, Karsenty G, Crabtree GR. Calcineurin/NFAT signaling in osteoblasts regulates bone mass. Dev Cell. 2006 Jun;10(6):771-82. Note: This research is featured on the cover of this issue of the journal. Go to: http://www.developmentalcell.com/
  5. Muller FL, Song W, Liu Y, Chaudhuri A, Pieke-Dahl S, Strong R, Huang TT, Epstein CJ, Roberts LJ 2nd, Csete M, Faulkner JA, Van Remmen H. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy. Free Radic Biol Med. 2006 Jun 1;40(11):1993-2004. Epub 2006 Feb 17.
  6. Levine ME, Stern RM, Koch KL. The effects of manipulating expectations through placebo and nocebo administration on gastric tachyarrhythmia and motion-induced nausea. Psychosom Med. 2006 May-Jun;68(3):478-86.
  7. Moore SR, Papworth D, Grosovsky AJ. Non-random distribution of instability-associated chromosomal rearrangement breakpoints in human lymphoblastoid cells. Mutat Res. 2006 May 20; [Epub ahead of print]
  8. Lai F, Macmillan J, Daudelin DH, Kent DM. The potential of training to increase acceptance and use of computerized decision support systems for medical diagnosis. Hum Factors. 2006 Spring;48(1):95-108.
  9. Sutter JU, Campanoni P, Blatt MR, Paneque M. Setting SNAREs in a different wood. Traffic. 2006 Jun;7(6):627-38.
  10. Biggiogera M, Fabene P, Zancanaro C. DADLE: A cue to human "hibernation"? J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):115-8. Note: This and the following five papers were presented at the Fourth IAA Symposium on "Realistic Near-Term Advanced Scientific Space Missions" in Aosta, Italy on July 4-6, 2005. The papers focus on hibernation and space flight.
  11. Strijkstra AM. Good and bad in the hibernating brain. J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):119-23.
  12. Freitas I, Bertone V, Guarnaschelli C, Boncompagni E, Vairetti M, Ferrigno A, Rizzo V, Reiter RJ. Rationale for the use of melatonin as a protective agent against cosmic radiation and ischemia-reperfusion damage in long term spaceflight. J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):124-9.
  13. Malatesta M. The cell nucleus in physiological and experimentally induced hypometabolism. J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):130-3.
  14. Palchykova S, Tobler I. Sleep, torpor and memory impairment. J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):134-8.
  15. Singer D. Human hibernation for space flight: Utopistic vision or realistic possibility? J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):139-43.

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