NASA Spaceline 9 June 2006 Current Space Life Science Awareness
Posted: Tuesday, June 27, 2006
PubMed's abstract is linked when available and each will open in a new window.
Liu C, Hadjiargyrou M.Identification and characterization of the Mustang promoter: Regulation by AP-1 during myogenic differentiation.Bone. 2006 May 26; [Epub ahead of print](HSR&T PI: M. Hadjiargyrou)
Sinha S, Sinha U, Edgerton VR.In vivo diffusion tensor imaging of the human calf muscle.J Magn Reson Imaging. 2006 May 25; [Epub ahead of print](HSR&T PI: S. Sinha)
Hamilton SA, Pecaut MJ, Gridley DS, Travis ND, Bandstra ER, Willey JS, Nelson G, Bateman TA.A murine model for bone loss from therapeutic and space-relevant sources of radiation.J Appl Physiol. 2006 Jun 1; [Epub ahead of print](HSR&T PIs: G. Nelson, T.A. Bateman)Note:
This paper reports the development of an animal model, which had not previously existed, to study the cause of radiation-induced bone loss. Effects of therapeutic-level and space flight-level radiation on bone loss are reported.
Fuller PM, Fuller CA.Genetic evidence for a neurovestibular influence on the mammalian circadian pacemaker.J Biol Rhythms. 2006 Jun;21(3):177-84.(HSR&T PI: C.A. Fuller)Note:
From paper: "In summary, the results of the present study (1) provide the first neurobehavioral evidence for a vestibular-CTS interrelationship, (2) contribute to our understanding of the regulation of the intrinsic circadian period, (3) suggest a novel afferent role for the macular gravity receptors in transducing activitybased nonphotic stimuli, (4) may have important implications for space-bound individuals, and, perhaps most important, (5) have practical implications for understanding the pathophysiology of, and developing treatments for, circadian and circadian sleep-wake disorders with vestibular etiologies."
Indic P, Gurdziel K, Kronauer RE, Klerman EB.Development of a two-dimension manifold to represent high dimension mathematical models of the intracellular mammalian circadian clock.J Biol Rhythms. 2006 Jun;21(3):222-32.(HSR&T PI: E.B. Klerman)
Levine ME, Stern RM, Koch KL.The effects of manipulating expectations through placebo and nocebo administration on gastric tachyarrhythmia and motion-induced nausea.Psychosom Med. 2006 May-Jun;68(3):478-86.
Moore SR, Papworth D, Grosovsky AJ.Non-random distribution of instability-associated chromosomal rearrangement breakpoints in human lymphoblastoid cells.Mutat Res. 2006 May 20; [Epub ahead of print]
Biggiogera M, Fabene P, Zancanaro C.
DADLE: A cue to human "hibernation"?J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):115-8.Note:
This and the following five papers were presented at the Fourth IAA Symposium on "Realistic Near-Term Advanced Scientific Space Missions" in Aosta, Italy on July 4-6, 2005. The papers focus on hibernation and space flight.
Good and bad in the hibernating brain.J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):119-23.
Freitas I, Bertone V, Guarnaschelli C, Boncompagni E, Vairetti M, Ferrigno A, Rizzo V, Reiter RJ.
Rationale for the use of melatonin as a protective agent against cosmic radiation and ischemia-reperfusion damage in long term spaceflight.J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):124-9.
The cell nucleus in physiological and experimentally induced hypometabolism.J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):130-3.
Palchykova S, Tobler I.
Sleep, torpor and memory impairment.J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):134-8.
Human hibernation for space flight: Utopistic vision or realistic possibility?J Br Interplanet Soc. 2006 Mar-Apr;59(3-4):139-43.