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NASA Spaceline 29 September 2006 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Tuesday, October 17, 2006

PubMed's abstract is linked when available and each will open in a new window.

  1. Paddon-Jones D, Sheffield-Moore M, Cree MG, Hewlings SJ, Aarsland A, Wolfe RR, Ferrando AA. Atrophy and impaired muscle protein synthesis during prolonged inactivity and stress. J Clin Endocrinol Metab. 2006 Sep 19; [Epub ahead of print] (HSR&T PIs: R.R. Wolfe, A.A. Ferrando) Note: From paper: "In conclusion, chronic inactivity and stress exacerbates muscle protein catabolism via a chronic reduction in muscle protein synthesis despite an increase in precursor availability and with no concomitant change in muscle protein breakdown. Understanding these key physiologic perturbations is crucial in the development of targeted interventional strategies to promote anabolism and facilitate recovery following inactivity associated with illness or injury." This paper can currently be obtained online without charge.
  2. McClung JM, Davis JM, Carson JA. Ovarian hormone status and skeletal muscle inflammation during recovery from disuse. Exp Physiol. 2006 Sep 21; [Epub ahead of print] (HSR&T PI: J.M. McClung, American College of Sports Medicine/NASA Space Physiology Research Grant)
  3. Yingling VR, Xiang Y, Raphan T, Schaffler MB, Koser K, Malique R. The effect of a short-term delay of puberty on trabecular bone mass and structure in female rats: A texture-based and histomorphometric analysis. Bone. 2006 Sep 14; [Epub ahead of print] (HSR&T PI: M.B. Schaffler)
  4. McNeil AK, Rescher U, Gerke V, McNeil PL. The requirement for annexin A1 in plasma membrane repair. J Biol Chem. 2006 Sep 19; [Epub ahead of print] (HSR&T PI: P.L. McNeil) Note: This paper can currently be obtained online without charge.
  5. Price EM, Prather RS, Foley CM. Multipotent adult progenitor cell lines originating from the peripheral blood of green fluorescent protein transgenic swine. Stem Cells Dev. 2006 Aug;15(4):507-22. (HSR&T PI: C.M. Foley) Note: This research is featured on the cover of this issue of the journal.
  6. Smith SM, Mathews Oliver SA, Zwart SR, Kala G, Kelly PA, Goodwin JS, Dyer CB. Nutritional status is altered in the self-neglecting elderly. J Nutr. 2006 Oct;136(10):2534-41. Note: Most biochemical analyses were performed at Johnson Space Center.
  7. Radisic M, Park H, Chen F, Salazar-Lazzaro JE, Wang Y, Dennis R, Langer R, Freed LE, Vunjak-Novakovic G. Biomimetic approach to cardiac tissue engineering: Oxygen carriers and channeled scaffolds. Tissue Eng. 2006 Aug;12(8):2077-91. (HSR&T PI: L.E. Freed) Note: This research is featured on the cover of this issue of the journal.
  8. Esue O, Carson AA, Tseng Y, Wirtz D. A direct interaction between actin and vimentin filaments mediated by the tail domain of vimentin. J Biol Chem. 2006 Aug 9; [Epub ahead of print] (HSR&T PI: D. Wirtz) Note: This paper can currently be obtained online without charge.
  9. Daniels BR, Masi BC, Wirtz D. Probing single-cell micromechanics in vivo: The microrheology of C. elegans developing embryos. Biophys J. 2006 Jun 15;90(12):4712-9. Epub 2006 Mar 31. (HSR&T PI: D. Wirtz)
  10. Arenas-Mena C, Cameron RA, Davidson EH. Hindgut specification and cell-adhesion functions of Sphox11/13b in the endoderm of the sea urchin embryo. Dev Growth Differ. 2006 Sep;48(7):463-72. (HSR&T PI: E.H. Davidson)

Other papers of interest:

  1. Xu S, Yu J. Beneath the minerals, a layer of round lipid particles was identified to mediate collagen calcification in compact bone formation. Biophys J. 2006 Sep 15; [Epub ahead of print] Note: Paper from the Florida Space Research Institute, Kennedy Space Center. This paper can currently be obtained online without charge.
  2. Chung DJ, Castro CH, Watkins M, Stains JP, Chung MY, Szejnfeld VL, Willecke K, Theis M, Civitelli R. Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43. J Cell Sci. 2006 Sep 19; [Epub ahead of print]
  3. Matsushima Y, Nanri H, Nara S, Okufuji T, Ohta M, Hachisuka K, Ikeda M. Hindlimb unloading decreases thioredoxin-related antioxidant proteins and increases thioredoxin-binding protein-2 in rat skeletal muscle. Free Radic Res. 2006 Jul;40(7):715-22.
  4. Mozaffar T, Haddad F, Zeng M, Zhang LY, Adams GR, Baldwin KM. Molecular and cellular defects of skeletal muscle in an animal model of acute quadriplegic myopathy. Muscle Nerve. 2006 Sep 11; [Epub ahead of print]
  5. Boonyarom O, Inui K. Atrophy and hypertrophy of skeletal muscles: Structural and functional aspects. Acta Physiol (Oxf). 2006 Oct;188(2):77-89.
  6. Uchakin PN, Uchakina ON, Morukov BV, Larina IM, Bogdanova NB, Mezentseva V, Tobin BV, Ershov FI. [The endogenous regulation of the cytokine disbalance in humans subjected to simulated spaceflight environment] Vestn Ross Akad Med Nauk. 2006;(7):15-20. Russian. Note: Results from SFINCSS (Simulation of Flight of International Crew on Space Station) study.
  7. Yakhnitsa V, Barmack NH. Antiphasic Purkinje cell responses in mouse uvula-nodulus are sensitive to static roll-tilt and topographically organized. Neuroscience. 2006 Sep 12; [Epub ahead of print]
  8. Bringoux L, Bourdin C, Nougier V, Raphel C. Effects of external feedback about body tilt: Influence on the Subjective Proprioceptive Horizon. Neurosci Lett. 2006 Sep 16; [Epub ahead of print]
  9. Yang JS, Jing XG, Li WJ, Wang ZZ, Zhou GM, Wang JF, Dang BR, Gao QX, Walsh L. Correlation between initial chromatid damage and survival of various cell lines exposed to heavy charged particles. Radiat Environ Biophys. 2006 Sep 9; [Epub ahead of print]
  10. Facius R. No evidence for the causation by cosmic radiation of nuclear cataracts in pilots. Arch Ophthalmol. 2006 Sep;124(9):1369-70; author reply 1370-1. Note: This letter comments on an earlier paper on this subject.
  11. Zee PC, Turek FW. Sleep and health: Everywhere and in both directions. Arch Intern Med. 2006 Sep 18;166(16):1686-8. Note: This editorial introduces a special issue of this journal on the topic of sleep and health.
  12. Ohyabu Y, Kida N, Kojima H, Taguchi T, Tanaka J, Uemura T. Cartilaginous tissue formation from bone marrow cells using rotating wall vessel (RWV) bioreactor. Biotechnol Bioeng. 2006 Sep 19; [Epub ahead of print] Note: From paper: "an experiment of transplanting the tissue formed by the RWV bioreactor to large osteochondral defects is under progress and will be published elsewhere."
  13. Raven JA, Cockell CS. Influence on photosynthesis of starlight, moonlight, planetlight, and light pollution (reflections on photosynthetically active radiation in the universe). Astrobiology. 2006 Aug;6(4):668-75.

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