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NASA Spaceline 27 October 2006 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Tuesday, November 14, 2006

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Sandri M, Lin J, Handschin C, Yang W, Arany ZP, Lecker SH, Goldberg AL, Spiegelman BM. PGC-1{alpha} protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription. Proc Natl Acad Sci U S A. 2006 Oct 19; [Epub ahead of print] (HSR&T PI: A.L. Goldberg)
  2. Turner RT, Evans GL, Lotinun S, Lapke PD, Iwaniec UT, Morey-Holton E. Dose response effects of intermittent parathyroid hormone on cancellous bone in hindlimb unloaded rats. J Bone Miner Res. 2006 Oct 16; [Epub ahead of print] (HSR&T PI: R.T. Turner)
  3. Xiang Y, Yingling VR, Malique R, Chao Yang Li, Schaffler MB, Raphan T. Comparative assessment of bone mass and structure using texture-based and histomorphometric analyses. Bone. 2006 Oct 16; [Epub ahead of print] (HSR&T PI: M.B. Schaffler)
  4. Moore ST, Macdougall HG, Gracies JM, Cohen HS, Ondo WG. Long-term monitoring of gait in Parkinson's disease. Gait Posture. 2006 Oct 12; [Epub ahead of print] (HSR&T PI: S.T. Moore)
  5. Limoli CL, Giedzinski E, Baure J, Rola R, Fike JR. Altered growth and radiosensitivity in neural precursor cells subjected to oxidative stress. Int J Radiat Biol. 2006 Sep;82(9):640-7. (HSR&T PI: C.L. Limoli)
  6. Madhusoodanan KS, Murad F. NO-cGMP signaling and regenerative medicine involving stem cells. Neurochem Res. 2006 Oct 18; [Epub ahead of print] (HSR&T PI: F. Murad)
  7. Szewczyk NJ, Udranszky IA, Kozak E, Sunga J, Kim SK, Jacobson LA, Conley CA. Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction. J Exp Biol. 2006 Oct 15;209(Pt 20):4129-39. (HSR&T PI: C.A. Conley)
  8. Panait L, Merrell RC, Rafiq A, Dudrick SJ, Broderick TJ. Virtual reality laparoscopic skill assessment in microgravity. J Surg Res. 2006 Oct 10; [Epub ahead of print] Note: Decreased efficiency and increased injury were observed in laparoscopic skill assessment tests performed during parabolic flight.
  9. Jordan NC, Saleh JH, Newman DJ. The extravehicular mobility unit: A review of environment, requirements, and design changes in the US spacesuit. Acta Astronaut. 2006 Dec;59(12):1135-45. (HSR&T PI: D.J. Newman)
  10. Haque AU, Rokkam M, De Carlo AR, Wereley ST, Roux SJ, Irazoqui PP, Porterfield DM. A MEMS fabricated cell electrophysiology biochip for in silico calcium measurements. Sens Actuators B Chem. 2006 Oct 10; [Epub ahead of print] Note: This device, designed to measure calcium flux around fern spores in microgravity flight experiments, can be adapted to other cell physiology and biomedical applications, according to the authors.
  11. Porterfield DM. Measuring metabolism and biophysical flux in the tissue, cellular and sub-cellular domains: Recent developments in self-referencing amperometry for physiological sensing. Biosens Bioelectron. 2006 Jul 24; [Epub ahead of print]

Other papers of interest:

  1. Richardson RS, Secher NH, Tschakovsky ME, Proctor DN, Wray DW. Metabolic and vascular limb differences affected by exercise, gender, age, and disease. Med Sci Sports Exerc. 2006 Oct;38(10):1792-6. Note: This was one of five papers in this issue of the journal deriving from the symposium, ?Skeletal Muscle Blood Flow and Metabolism: Are There Inherent Limb Differences??
  2. Lindenberger M, Lanne T. Sex-related effects on venous compliance and capillary filtration in the lower limb. Am J Physiol Regul Integr Comp Physiol. 2006 Oct 12; [Epub ahead of print]
  3. Cirovic S, Walsh C, Fraser WD, Gulino A. Venous filling and elastance in the calf positioned above and below heart level. Aviat Space Environ Med. 2006 Oct;77(10):1009-14.
  4. Piantadosi CA. Lunar exploration and the advancement of biomedical research: A physiologist's view. Aviat Space Environ Med. 2006 Oct;77(10):1084-6.
  5. Tidball JG, Wehling-Henricks M. Macrophages promote muscle membrane repair and muscle fiber growth and regeneration during modified muscle loading in vivo. J Physiol. 2006 Oct 12; [Epub ahead of print] Note: This paper can currently be obtained online without charge.
  6. Sanchez RJ, Liu J, Rao S, Shah P, Smith R, Rahman T, Cramer SC, Bobrow JE, Reinkensmeyer DJ. Automating arm movement training following severe stroke: Functional exercises with quantitative feedback in a gravity-reduced environment. IEEE Trans Neural Syst Rehabil Eng. 2006 Sep;14(3):378-89.
  7. Hafed ZM, Krauzlis RJ. Ongoing eye movements constrain visual perception. Nat Neurosci. 2006 Nov;9(11):1449-57. Epub 2006 Oct 8.
  8. Marchetti F, Coleman MA, Jones IM, Wyrobek AJ. Candidate protein biodosimeters of human exposure to ionizing radiation. Int J Radiat Biol. 2006 Sep;82(9):605-39.
  9. Rapp D. Radiation effects and shielding requirements in human missions to the Moon and Mars. Mars. 2006;2:46-71. Note: This paper can be obtained online without charge.
  10. Rapp D. Mars life support systems. Mars. 2006;2:72-82. Note: This paper can be obtained online without charge.
  11. Czeisler CA. Sleep deficit: The performance killer. A conversation with Harvard Medical School Professor Charles A. Czeisler. Harv Bus Rev. 2006 Oct;84(10):53-9, 148.
  12. Chachisvilis M, Zhang YL, Frangos JA. G protein-coupled receptors sense fluid shear stress in endothelial cells. Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15463-8. Epub 2006 Oct 9.
  13. Kuya N, Kato M, Sato Y, Kaneta T, Sato S. Comparative study of cellular structures implicated in gravisensing in statocytes of primary and lateral roots of Vigna angularis. Protoplasma. 2006 Oct 6; [Epub ahead of print]
  14. Eichler P, Seine R, Khanina E, Schon A. Astronaut training for the European ISS contributions Columbus module and ATV. Acta Astronaut. 2006 Dec;59(12):1146-52.
  15. Barer AS. [The ergonomic aspects of space vehicle manual motion control during re-entry] Aviakosm Ekolog Med. 2006 Mar-Apr;40(2):3-8. Review. Russian.
  16. Kotovskaia AR, Koloteva MI, Luk'ianiuk VIu, Vil'-Vil'iams IF, Bazhanova TM. [On medical screening of civilian candidates for cosmonauts by exposure to the head-to-pelvis acceleration profiles] Aviakosm Ekolog Med. 2006 Mar-Apr;40(2):9-13. Russian.
  17. Rykova MP, Gertsik IuG, Antropova EN, Buravkova LB. [Immunoglobulin e and allergen-specific IgE antibodies in cosmonauts before and after long-duration missions on the International Space Station] Aviakosm Ekolog Med. 2006 Mar-Apr;40(2):19-22. Russian. Note: ISS results.
  18. Stepanova SI, Galichii VA. [Dynamics of operator's efficiency under the condition of long continuous vigil] Aviakosm Ekolog Med. 2006 Mar-Apr;40(2):23-8. Russian.
  19. Durnova GN, Kaplanskii AS, Loginov VI. [Dynamics of the structural recovery of the rat's tibia from suspension-produced osteopenia] Aviakosm Ekolog Med. 2006 Mar-Apr;40(2):29-31. Russian.
  20. Modin AIu. [Functional insufficiency of the venous valve apparatus and venous return from the lower extremities in humans during the standing test] Aviakosm Ekolog Med. 2006 Mar-Apr;40(2):31-6. Russian.
  21. Pakhomova AA, Mukhamedieva LN, Mikos KN. [Air quality monitoring on the International Space Station] Aviakosm Ekolog Med. 2006 Mar-Apr;40(2):46-9. Russian.
  22. Krasnov IB, D'iachkova LN. [The acceleration of ultrastructure changes of synapses in somatosensory cortex of the rats at repeated simulation of weightlessness effects] Aviakosm Ekolog Med. 2006 Mar-Apr;40(2):53-4. Russian.
  23. Vorona AA, Zhdan'ko IM. [Improvement of the reliability of air crew spatial orientation with the psycho-educational methods] Aviakosm Ekolog Med. 2006 Mar-Apr;40(2):55-8. Russian.
  24. Shibanov GP. [In-flight maintenance and repair of equipment of long-operating orbital stations] Aviakosm Ekolog Med. 2006 Mar-Apr;40(2):59-63. Russian.

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