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NASA Spaceline 5 January 2007 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Friday, January 26, 2007

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Iwasaki KI, Levine BD, Zhang R, Zuckerman JH, Pawelczyk JA, Diedrich A, Ertl AC, Cox JF, Giller CA, Ray CA, Lane LD, Buckey JC, Baisch F, Eckberg DL, Robertson D, Biaggioni I, Blomqvist CG. Human cerebral autoregulation before, during, and after spaceflight. J Physiol. 2006 Dec 21; [Epub ahead of print] (HSR&T PIs: F. Baisch, D.L. Eckberg, D. Robertson, C.G. Blomqvist) Note: STS-90 (Neurolab) results. This paper can currently be obtained online without charge.
  2. Lang TF. What do we know about fracture risk in long-duration spaceflight? J Musculoskelet Neuronal Interact. 2006 Oct-Dec;6(4):319-21. (HSR&T PI: T.F. Lang) Note: This paper and the following four short papers and one paper in the ?Other papers of interest? section derive from a session on bone in microgravity environments held at the 36th International Sun Valley Workshop on Skeletal Tissue Biology, Sun Valley, Idaho, July 30-August 2, 2006. The papers can be obtained online without charge via the publisher?s site.
  3. Shapiro JR. Microgravity and drug effects on bone. J Musculoskelet Neuronal Interact. 2006 Oct-Dec;6(4):322-3. (HSR&T PI: J.R. Shapiro)
  4. Bloomfield SA. Does altered blood flow to bone in microgravity impact on mechanotransduction? J Musculoskelet Neuronal Interact. 2006 Oct-Dec;6(4):324-6. (HSR&T PI: S.A. Bloomfield)
  5. Midura RJ, Su X, Androjna C. A simulated weightlessness state diminishes cortical bone healing responses. J Musculoskelet Neuronal Interact. 2006 Oct-Dec;6(4):327-8. (HSR&T PI: R.J. Midura)
  6. Bloomfield SA. (Session Chair) Summary - Bone in Microgravity Environments: 'Houston, we have a problem'. J Musculoskelet Neuronal Interact. 2006 Oct-Dec;6(4):329-30. (HSR&T PI: S.A. Bloomfield)
  7. Kataoka A, Tanner BCW, Macpherson JM, Xu X, Wang Q, Regnier M, Daniel TL, Chase PB. Spatially explicit, nano-mechanical models of the muscle half-sarcomere: Implications for biomechanical tuning in atrophy and fatigue. Acta Astronaut. 2007 Jan;60(2):111-8. (HSR&T PI: P.B. Chase)
  8. Shuryak I, Sachs RK, Hlatky L, Little MP, Hahnfeldt P, Brenner DJ. Radiation-induced leukemia at doses relevant to radiation therapy: Modeling mechanisms and estimating risks. J Natl Cancer Inst. 2006 Dec 20;98(24):1794-806. (HSR&T PI: L. Hlatky) Note: This paper can be obtained online without charge.
  9. Yan B, Wang H, Rabbani ZN, Zhao Y, Li W, Yuan Y, Li F, Dewhirst MW, Li CY. Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation. Cancer Res. 2006 Dec 15;66(24):11565-70. (HSR&T PI: C.Y. Li)
  10. Kim MH, Cucinotta FA, Wilson JW. A temporal forecast of radiation environments for future space exploration missions. Radiat Environ Biophys. 2006 Dec 13; [Epub ahead of print] (HSR&T PIs: F.A. Cucinotta, J.W. Wilson)
  11. Van Dongen HP. Shift work and inter-individual differences in sleep and sleepiness. Chronobiol Int. 2006;23(6):1139-47. (HSR&T PI: H.P. Van Dongen)

Other papers of interest:

  1. Berg HE, Eiken O, Miklavcic L, Mekjavic IB. Hip, thigh and calf muscle atrophy and bone loss after 5-week bedrest inactivity. Eur J Appl Physiol. 2006 Dec 22; [Epub ahead of print]
  2. van der Velden J, Langen R, Kelders M, Willems J, Wouters E, Janssen-Heininger Y, Schols A. Myogenic differentiation during regrowth of atrophied skeletal muscle is associated with inactivation of GSK-3{beta}. Am J Physiol Cell Physiol. 2006 Dec 13; [Epub ahead of print]
  3. Vico L. What do we know about alteration in the osteoblast phenotype with microgravity? J Musculoskelet Neuronal Interact. 2006 Oct-Dec;6(4):317-8.
  4. Perrien DS, Akel NS, Edwards PK, Carver AA, Bendre MS, Swain FL, Skinner RA, Hogue WR, Nicks KM, Pierson TM, Suva LJ, Gaddy D. Inhibin A is an endocrine stimulator of bone mass and strength. Endocrinology. 2006 Dec 28; [Epub ahead of print] Note: This paper can currently be obtained online without charge.
  5. Risso A, Turello M, Biffoni F, Antonutto G. Red blood cell senescence and neocytolysis in humans after high altitude acclimatization. Blood Cells Mol Dis. 2006 Dec 22; [Epub ahead of print] Note: Discovery of neocytolysis derived from space flight observations.
  6. Clement G, Arnesen TN, Olsen MH, Sylvestre B. Perception of longitudinal body axis in microgravity during parabolic flight. Neurosci Lett. 2006 Dec 13; [Epub ahead of print] Note: Parabolic flight results.
  7. Ceyte H, Cian C, Nougier V, Olivier I, Trousselard M. Role of gravity-based information on the orientation and localization of the perceived body midline. Exp Brain Res. 2007 Jan;176(3):504-9. Epub 2006 Nov 25.
  8. Chen BP, Uematsu N, Kobayashi J, Lerenthal Y, Krempler A, Yajima H, Lobrich M, Shiloh Y, Chen DJ. ATM is essential for DNA-PKcs phosphorylations at T2609 cluster upon DNA double strand break. J Biol Chem. 2006 Dec 21; [Epub ahead of print] Note: This paper can currently be obtained online without charge.
  9. Hochleitner B, Hengster P, Bucher H, Ladurner R, Schneeberger S, Krismer A, Kleinsasser A, Barnas U, Klima G, Margreiter R. Significant survival prolongation in pigs with fulminant hepatic failure treated with a novel microgravity-based bioartificial liver. Artif Organs. 2006 Dec;30(12):906-14. Note: Microgravity simulated by rotating bioreactor.
  10. Paul AL, Ferl RJ, Meisel MW. High magnetic field induced changes of gene expression in Arabidopsis. Biomagn Res Technol. 2006 Dec 22;4(1):7 [Epub ahead of print] Note: From introduction: ?This research was initially driven by an interest in using magnetic levitation as a ground-based model for the effects of a reduced gravity environment on plant gene expression.? This paper can be obtained online without charge.
  11. Baranov VM, Polikarpov NA, Novikova ND, Deshevaya EA, Poddubko SV, Svistunova YuV, Tsetlin VV. [Main results of the Biorisk experiment on the International Space Station] Aviakosm Ekolog Med. 2006 May-Jun;40(3):3-9. Russian. Note: ISS results.
  12. Ivanova SM, Morukov BV, Labetskaya OI, Yarlykova YuV, Levina AA, Kozinets GI. [Morphobiochemical assay of the red blood system in members of the prime crews of the International Space Station] Aviakosm Ekolog Med. 2006 May-Jun;40(3):9-15. Russian. Note: ISS results.
  13. Yusupova AK, Guschin VI, Popova II. [Communication within the mission control-space crew loop: The socio-psychological aspects] Aviakosm Ekolog Med. 2006 May-Jun;40(3):16-9. Russian.
  14. Grigoriev AI, Durnova GN, Kaplansky AS. [Action of estradiol, calcitonin and weight-loading on the development of osteopenia in tail-suspended female rats] Aviakosm Ekolog Med. 2006 May-Jun;40(3):20-4. Russian.
  15. Lobachik VI, Gordeev YuV, Nosovsky AM, Pischulina GN, Chupushtanov SA, Korolkov VI, Krotov VP. [Body liquids ratio and postural stability of head-down tilted apes in the periods of transition into the active vertical position] Aviakosm Ekolog Med. 2006 May-Jun;40(3):24-8. Russian.
  16. Krasnov IB, Alekseev EI, Loginov VI. [Role of the endocrine glands in divergence of plastic processes and energy metabolism in rats after extended exposure to hypergravity: Cytologic investigation] Aviakosm Ekolog Med. 2006 May-Jun;40(3):29-34. Russian.
  17. Vorozhtsova SV, Shafirkin AV, Fedorenko BS. [Relative biological effectiveness of accelerated heavy ions and fast neutrons estimated from frequency of aberration mytoses in the retinal epithelium] Aviakosm Ekolog Med. 2006 May-Jun;40(3):42-9. Russian.
  18. Barantseva MYu, Ivanova SM, Pakhomova AA, Nikitin EI, Vorozhtsova SV. [Cytogenetic and biochemical assay of an unidirectional effect of chronic combined exposure of laboratory animals to isoeffective concentrations of chemical substances] Aviakosm Ekolog Med. 2006 May-Jun;40(3):50-4. Russian.
  19. Fedorenko BS, Petrov VM, Smirnova OA, Vorozhtsova SV, Abrosimova AN. [Experimental studies of the relative biological effectiveness of accelerated charged particles varying in energy] Aviakosm Ekolog Med. 2006 May-Jun;40(3):55-63. Russian.

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