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NASA Spaceline 6 April 2007 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Friday, May 4, 2007

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Macias BR, Cao P, Watenpaugh DE, Hargens AR. LBNP treadmill exercise maintains spine function and muscle strength in identical twins during 28-days simulated microgravity. J Appl Physiol. 2007 Mar 29; [Epub ahead of print] (HSR&T PI: A.R. Hargens)
  2. Hamrick MW, Shi X, Zhang W, Pennington C, Thakore H, Haque M, Kang B, Isales CM, Fulzele S, Wenger KH. Loss of myostatin (GDF8) function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading. Bone. 2007 Feb 23; [Epub ahead of print] (HSR&T PI: C.M. Isales)
  3. Provenzano PP, Alejandro-Osorio AL, Grorud KW, Martinez DA, Grindeland RE, Vailas AC, Vanderby R Jr. Systemic administration of IGF-I enhances healing in collagenous extracellular matrices: Evaluation of loaded and unloaded ligaments. BMC Physiol. 2007 Mar 26;7(1):2 [Epub ahead of print] (HSR&T PI: D.A. Martinez) Note: This paper can be obtained online without charge.
  4. Morey-Holton ER, Hill EL, Souza KA. Animals and spaceflight: From survival to understanding. J Musculoskelet Neuronal Interact. 2007 Jan-Mar;7(1):17-25. Note: This paper and the next paper and the second and third papers in the Other citations of interest section derive from the Second International Conference on Osteoporosis and Bone Research held October 2005 in Chengdu, China. This paper can be obtained online without charge.
  5. Leblanc AD, Spector ER, Evans HJ, Sibonga JD. Skeletal responses to space flight and the bed rest analog: A review. J Musculoskelet Neuronal Interact. 2007 Jan-Mar;7(1):33-47. Note: This paper can be obtained online without charge.
  6. Furochi H, Nikawa T, Hirasaka K, Suzue N, Ishidoh K, Onishi Y, Ogawa T, Yamada C, Suzuki H, Higashibata A, Oarada M, Kishi K, Yasui N. Distinct gene expression profiles in the femora of rats exposed to spaceflight, tail-suspension and denervation. Biol Sci Space. 2006 Dec;20(3):80-91. Note: Includes STS-58 results.
  7. Wu F, Zhang R, Burns FJ. Gene expression and cell cycle arrest in a rat keratinocyte line exposed to (56)Fe ions. J Radiat Res (Tokyo). 2007 Mar;48(2):163-70. (HSR&T PI: F.J. Burns) Note: This paper can be obtained online without charge.
  8. Kennedy AR, Guan J, Ware JH. Countermeasures against space radiation induced oxidative stress in mice. Radiat Environ Biophys. 2007 Mar 27; [Epub ahead of print] (HSR&T PI: A.R. Kennedy)
  9. Sannita WG, Peachey NS, Strettoi E, Ball SL, Belli F, Bidoli V, Carozzo S, Casolino M, Di Fino L, Picozza P, Pignatelli V, Rinaldi A, Saturno M, Schardt D, Vazquez M, Zaconte V, Narici L. Electrophysiological responses of the mouse retina to (12)C ions. Neurosci Lett. 2007 Apr 18;416(3):231-5. Epub 2007 Feb 24.
  10. Shephard JM, Kho S, Chen J, Kosslyn SM. MiniCog: A method for administering psychological tests and experiments on a handheld personal digital assistant. Behav Res Methods. 2006 Nov;38(4):648-55. (HSR&T PI: S.M. Kosslyn)
  11. Tosini G, Aguzzi J, Bullock NM, Liu C, Kasamatsu M. Effect of photoreceptor degeneration on circadian photoreception and free-running period in the Royal College of Surgeons rat. Brain Res. 2007 Mar 1; [Epub ahead of print] (HSR&T PI: G. Tosini)
  12. Chaudhuri A, Bowling K, Funderburk C, Lawal H, Inamdar A, Wang Z, O'Donnell JM. Interaction of genetic and environmental factors in a Drosophila parkinsonism model. J Neurosci. 2007 Mar 7;27(10):2457-67. (HSR&T PI: J.M. O?Donnell) Note: This paper is highlighted in "This Week in the Journal."

Other papers of interest:

  1. Hopkins SR, Henderson AC, Levin DL, Yamada K, Arai T, Buxton RB, Prisk GK. Vertical gradients in regional lung density and perfusion in the supine human lung: The SlinkyŽ effect. J Appl Physiol. 2007 Mar 29; [Epub ahead of print]
  2. Martin RB. The importance of mechanical loading in bone biology and medicine. J Musculoskelet Neuronal Interact. 2007 Jan-Mar;7(1):48-53. Note: This paper can be obtained online without charge.
  3. Recker RR. Skeletal fragility and bone quality. J Musculoskelet Neuronal Interact. 2007 Jan-Mar;7(1):54-5. Note: This paper can be obtained online without charge.
  4. Glass DA 2nd, Karsenty G. In vivo analysis of Wnt signaling in bone. Endocrinology. 2007 Mar 29; [Epub ahead of print] Note: This paper can currently be obtained online without charge.
  5. Othman H, Thonar EJ, Mao JJ. Modulation of neonatal growth plate development by ex vivo intermittent mechanical stress. J Biomech. 2007 Mar 6; [Epub ahead of print]
  6. Zhang P, Chen X, Fan M. Signaling mechanisms involved in disuse muscle atrophy. Med Hypotheses. 2007 Mar 19; [Epub ahead of print]
  7. Kumei Y, Morita S, Katano H, Akiyama H, Hirano M, Oyha K, Shimokawa H. Microgravity signal ensnarls cell adhesion, cytoskeleton, and matrix proteins of rat osteoblasts: Osteopontin, CD44, osteonectin, and alpha-tubulin. Ann N Y Acad Sci. 2006 Dec;1090:311-7. Note: STS-65 results.
  8. Manzoni D. The cerebellum and sensorimotor coupling: Looking at the problem from the perspective of vestibular reflexes. Cerebellum. 2007;6(1):24-37.
  9. Vidal L, Morin LP. Absence of normal photic integration in the circadian visual system: Response to millisecond light flashes. J Neurosci. 2007 Mar 28;27(13):3375-82. Note: This paper is highlighted in "This Week in the Journal."
  10. Nikawa T, Nakao R, Asanoma Y, Hayashi R, Furochi H, Hirasaka K, Kishi K. A skeletal muscle-derived secretory protein, attractin, upregulates UCP-2 expression in mouse 3T3-L1 adipocytes. Biol Sci Space. 2006 Nov;20(2):33-9. Note: Includes STS-90 results.
  11. Shinkai T, Kashiwagi A, Kashiwagi K, Matsuda M, Urano S, Sato H, Kubo H, Furuno N, Itai M, Watanabe M, Yoshitome S, Fujii H, Yamashita M. Effects of hypergravity on pituitary-target organs in the frog, Xenopus laevis. Biol Sci Space. 2006 Nov;20(2):40-3.
  12. Takeda A, Mogami Y, Baba SA. Gravikinesis in Paramecium: Approach from the analysis on the swimming behavior of single cells. Biol Sci Space. 2006 Nov;20(2):44-7.
  13. Katayama N, Yamashita M, Wada H, Mitsuhashi J, Space Agriculture Task Force. [Space diet for habitation on Mars with entomophagy] Biol Sci Space. 2006 Nov;20(2):48-56. Japanese. Note: This article was previously published in English in the Journal of Space Technology and Science 21(2):27-38, 2005.
  14. Seki M, Imamizo-Sata M, Yamazaki T, Ishioka N, Higashibata A. Suppression of Rho activation process due to simulated microgravity induced cytoskeletal disorganization. Biol Sci Space. 2006 Dec;20(3):75-9.
  15. Furuno N, Tazawa I, Kashiwagi K, Kawakami S, Shinkai T, Yamashita M, Kashiwagi A. The effect of hypergravity on bipolar spindle formation of meiosis II in Xenopus oocytes. Biol Sci Space. 2006 Dec;20(3):92-4.

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