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NASA Spaceline 20 April 2007 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Thursday, May 10, 2007

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Kalb R, Solomon D. Space exploration, Mars, and the nervous system. Arch Neurol. 2007 Apr;64(4):485-90. Note: This paper briefly reviews the effects of space flight on the nervous system. Roberta Bondar comments on the paper in an article entitled: "Mars on balance: Twitching and dreaming."
  2. Miller LM, Little W, Schirmer A, Sheik F, Busa B, Judex S. Accretion of bone quantity and quality in the developing mouse skeleton. J Bone Miner Res. 2007 Apr 2; [Epub ahead of print] (HSR&T PI: S. Judex)
  3. Ponomarev AL, Belli M, Hahnfeldt PJ, Hlatky L, Sachs RK, Cucinotta FA. Subtraction of background damage in PFGE experiments on DNA fragment-size distributions. Radiat Environ Biophys. 2007 Apr 4; [Epub ahead of print] (HSR&T PIs: L. Hlatky/R.K. Sachs, F.A. Cucinotta)
  4. Rithidech KN, Honikel L, Simon SR. Radiation leukemogenesis: A proteomic approach. Exp Hematol. 2007 Apr;35(4 Suppl 1):117-24. (HSR&T PI: K.N. Rithidech)
  5. Sato M, Shames DS, Gazdar AF, Minna JD. A translational view of the molecular pathogenesis of lung cancer. J Thorac Oncol. 2007 Apr;2(4):327-43. (HSR&T PI: J.D. Minna) Note: This paper can be obtained online without charge via the publisher's site.
  6. Watson AB. The Spatial Standard Observer: A new tool for display metrology. Information Display. 2007 Jan;23(1):12-5. Note: A copy of this paper can be obtained via a NASA website. The paper is featured on the cover of the magazine (scroll to the right).
  7. Dunlap KL, Reynolds AJ, Tosini G, Kerr WW, Duffy LK. Seasonal and diurnal melatonin production in exercising sled dogs. Comp Biochem Physiol A Mol Integr Physiol. 2007 Feb 21; [Epub ahead of print] (HSR&T PI: G. Tosini)
  8. Li L, Wang X, Sasidharan R, Stolc V, Deng W, He H, Korbel J, Chen X, Tongprasit W, Ronald P, Chen R, Gerstein M, Wang Deng X. Global identification and characterization of transcriptionally active regions in the rice genome. PLoS ONE. 2007 Mar 14;2:e294. Note: This paper can be obtained online without charge.
  9. Mazza ME, Pang K, Martindale MQ, Finnerty JR. Genomic organization, gene structure, and developmental expression of three clustered otx genes in the sea anemone Nematostella vectensis. J Exp Zoolog B Mol Dev Evol. 2007 Mar 21; [Epub ahead of print] (HSR&T PI: M.Q. Martindale)

Other papers of interest:

  1. Eash J, Olsen A, Breur G, Gerrard D, Hannon K. FGFR1 inhibits skeletal muscle atrophy associated with hindlimb suspension. BMC Musculoskelet Disord. 2007 Apr 10;8(1):32 [Epub ahead of print] Note: This paper can be obtained online without charge.
  2. Enns DL, Raastad T, Ugelstad I, Belcastro AN. Calpain/calpastatin activities and substrate depletion patterns during hindlimb unweighting and reweighting in skeletal muscle. Eur J Appl Physiol. 2007 Apr 12; [Epub ahead of print]
  3. Kim SJ, Roy RR, Zhong H, Suzuki H, Ambartsumyan L, Haddad F, Baldwin KM, Edgerton VR. Electromechanical stimulation ameliorates inactivity-induced adaptations in the medial gastrocnemius of adult rats. J Appl Physiol. 2007 Apr 12; [Epub ahead of print]
  4. Kumei Y, Shimokawa H, Ohya K, Katano H, Akiyama H, Hirano M, Morita S. Small GTPase Ras and Rho expression in rat osteoblasts during spaceflight. Ann N Y Acad Sci. 2007 Jan;1095:292-9. Note: STS-65 results.
  5. Yamada S, Ganno T, Ohara N, Hayashi Y. Chitosan monomer accelerates alkaline phosphatase activity on human osteoblastic cells under hypofunctional conditions. J Biomed Mater Res A. 2007 Apr 5; [Epub ahead of print] Note: Microgravity was simulated with a clinostat.
  6. Deligianni DD, Apostolopoulos CA. Multilevel finite element modeling for the prediction of local cellular deformation in bone. Biomech Model Mechanobiol. 2007 Apr 13; [Epub ahead of print]
  7. Payne MW, Uhthoff HK, Trudel G. Anemia of immobility: Caused by adipocyte accumulation in bone marrow. Med Hypotheses. 2007 Apr 2; [Epub ahead of print] Note: This paper utilizes space flight, bed rest, and RWV results to support its hypothesis.
  8. Mazina NK, Larina IM, Khazanov VA, Shenkman BS, Tsapok PI, Zaitsev VB, Khorobrykh VG, Veselova OM, Tret'yakov VS. Protective effect of energy metabolism regulators in alteration of gravitation load under experimental conditions. Bull Exp Biol Med. 2006 Oct;142(4):441-6. English, Russian. Note: This is an English translation of a paper that appeared in Byulleten' Eksperimental'noi Biologii i Meditsiny 142(10):423-9, Oct 2006.
  9. Arshian M, Holtje RJ, Cotter LA, Rice CD, Cass SP, Yates BJ. Consequences of postural changes and removal of vestibular inputs on the movement of air in and out of the lungs of conscious felines. J Appl Physiol. 2007 Apr 12; [Epub ahead of print] Note: From abstract: "These results suggest that the role of the vestibular system in the control of breathing is to modify baseline respiratory parameters in proportion to the general intensity of ongoing movements, and not to rapidly alter ventilation in accordance with body position."
  10. Ifediba MA, Rajguru SM, Hullar TE, Rabbitt RD. The role of 3-canal biomechanics in angular motion transduction by the human vestibular labyrinth. Ann Biomed Eng. 2007 Mar 22; [Epub ahead of print]
  11. Deans MR, Antic D, Suyama K, Scott MP, Axelrod JD, Goodrich LV. Asymmetric distribution of Prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner ear. J Neurosci. 2007 Mar 21;27(12):3139-47. Note: This paper is featured on the cover of the journal.
  12. Vandewalle G, Gais S, Schabus M, Balteau E, Carrier J, Darsaud A, Sterpenich V, Albouy G, Dijk DJ, Maquet P. Wavelength-dependent modulation of brain responses to a working memory task by daytime light exposure. Cereb Cortex. 2007 Apr 2; [Epub ahead of print]
  13. Taramino G, Sauer M, Stauffer JL Jr, Multani D, Niu X, Sakai H, Hochholdinger F. The maize (Zea mays L.) RTCS gene encodes a LOB domain protein that is a key regulator of embryonic seminal and post-embryonic shoot-borne root initiation. Plant J. 2007 Apr 8; [Epub ahead of print]

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