NASA Spaceline 21 September 2007 Current Space Life Science Awareness
Posted: Friday, October 19, 2007
The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.
Lublinsky S, Ozcivici E, Judex S.An automated algorithm to detect the trabecular-cortical bone interface in micro-computed tomographic images.Calcif Tissue Int. 2007 Sep 9; [Epub ahead of print](PIs: S. Judex, C. Rubin)
Yang H, Anzenberg V, Held KD.The time dependence of bystander responses induced by iron-ion radiation in normal human skin fibroblasts.Radiat Res. 2007 Sep;168(3):292-8.(PI: K.D. Held)
Sajdel-Sulkowska EM.Brain development, environment and sex: What can we learn from studying graviperception, gravitransduction and the gravireaction of the developing CNS to altered gravity?Cerebellum. 2007 Apr 11;:1-17 [Epub ahead of print](PI: E.M. Sajdel-Sulkowska)Note:
This is a detailed review of this subject by a former PI.
Palmieri M, Schwind MA, Stevens MH, Edelmann RE, Kiss JZ.Effects of the myosin ATPase inhibitor 2,3-butanedione monoxime on amyloplast kinetics and gravitropism of Arabidopsis hypocotyls.Physiol Plant. 2007 Aug;130(4):613–26.(PIs: M. Palmieri, NASA Graduate Student Researcher Program, and J.Z. Kiss)
Dyachkova LN.Ultrastructural changes in somatosensory cortex of albino rats during space flight.Biol Bull Rus Acad Sci. 2007 Jun;34(3):307-9.Note:
STS-58 results. This is an English translation of the Russian original published in: Izv Akad Nauk Ser Biol. 2007 May-Jun;(3):372-5.
Hamilton MT, Hamilton DG, Zderic TW.The role of low energy expenditure and sitting on obesity, metabolic syndrome, type 2 diabetes, and cardiovascular disease.Diabetes. 2007 Sep 18; [Epub ahead of print]Note:
This paper focuses on the concept of "inactivity physiology," as exemplified by prolonged sitting. Of four listed tenets of inactivity physiology, "The third, and the central tenet for the paradigm of inactivity physiology is that some of the specific cellular and molecular processes explaining the responses during inactivity physiology vs. exercise physiology are qualitatively different from each other." (from paper)
Hornberger TA, Sukhija KB, Wang XR, Chien S.mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k).FEBS Lett. 2007 Oct 2;581(24):4562-6.Note:
This paper can be obtained online without charge if accessed via the journal's table of contents.
Vens C, Hofland I, Begg AC.Involvement of DNA polymerase beta in repair of ionizing radiation damage as measured by in vitro plasmid assays.Radiat Res. 2007 Sep;168(3):281-91.
Bhattacharjee Y.Is internal timing key to mental health?Science. 2007 Sep 14;317(5844):1488-90.Note:
This "News Focus" reviews evidence that circadian disturbances may play a role not only in seasonal depression, but also possibly in other mental ailments such as bipolar disorder.
Webb MA, Platton SL, Dennison AR, James RF.Immunohistochemical evidence that culture in the high aspect rotating vessel can up-regulate hormone expression in growth dedifferentiated PHHI-derived islet cells.In Vitro Cell Dev Biol Anim. 2007 Sep 11; [Epub ahead of print]Note:
From abstract: "through HARV technology, we have demonstrated that it is possible to reactivate insulin, glucagon, somatostatin, and GAD expression in PHHI-derived cells that had previously stopped expressing these markers."
Hu L, Cui D, Neill S, Cai W.OsEXPA4 and OsRWC3 are involved in asymmetric growth during gravitropic bending of rice leaf sheath bases.Physiol Plant. 2007 Aug;130(4):560–71.