NASA Spaceline 2 November 2007 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Wednesday, November 21, 2007

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Rubin CT, Capilla E, Luu YK, Busa B, Crawford H, Nolan DJ, Mittal V, Rosen CJ, Pessin JE, Judex S. Adipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signals. Proc Natl Acad Sci U S A. 2007 Oct 24; [Epub ahead of print] (PI: S. Judex) Note: The results reported in this paper were described in various news sources including the New York Times. This paper can be obtained online without charge.
  2. Kondo H, Limoli C, Searby ND, Almeida EA, Loftus DJ, Vercoutere W, Morey-Holton E, Giedzinski E, Mojarrab R, Hilton D, Globus RK. Shared oxidative pathways in response to gravity-dependent loading and gamma-irradiation of bone marrow-derived skeletal cell progenitors. Radiats Biol Radioecol. 2007 May-Jun;47(3):281-5. (PI: R.K. Globus)
  3. Maliev V, Popov D, Casey RC, Jones JA. Mechanisms of action for an anti-radiation vaccine in reducing the biological impact of high dose and dose-rate, low-linear energy transfer radiation exposure. Radiats Biol Radioecol. 2007 May-Jun;47(3):286-91.
  4. Yang H, Anzenberg V, Held KD. Effects of heavy ions and energetic protons on normal human fibroblasts. Radiats Biol Radioecol. 2007 May-Jun;47(3):302-6. (PI: K.D. Held)
  5. Gostimsky SA, Levinskikh MA, Sychev VN, Kokaeva ZG, Dribnokhodova OP, Khartina GA, Bingham G. The study of the genetic effects in generation of pea plants cultivated during the whole cycle of ontogenesis on the board of RS ISS. Russ J Genet 2007 Aug;43(8):869-74. (PI: G. Bingham) Note: ISS results. This is an English translation of the Russian original published in Genetika. 2007 Aug;43(8):1050-7.
  6. Hinman VF, Nguyen A, Davidson EH. Caught in the evolutionary act: Precise cis-regulatory basis of difference in the organization of gene networks of sea stars and sea urchins. Dev Biol. 2007 Sep 16; [Epub ahead of print] (PI: E.H. Davidson)
  7. Blakely EA, Chang PY. A review of ground-based heavy-ion radiobiology relevant to space radiation risk assessment. Part II: Cardiovascular and immunological effects. Adv Space Res. 2007;40(4):461-9. (PI: E.A. Blakely) Note: This paper and the following 8 papers plus 11 papers in the "Other papers of interest" section comprise an issue of this journal devoted to space radiation health and space radiation biology.
  8. George K, Durante M, Cucinotta FA. Chromosome aberrations in astronauts. Adv Space Res. 2007;40(4):483-90. (PI: F.A. Cucinotta)
  9. Rithidech KN, Supanpaiboon W, Honikel L, Whorton EB. Analysis of chromosomal damage after in vivo exposure to 56Fe ions by means of mFISH and micronucleus methods. Adv Space Res. 2007;40(4):491-500. (PI: K.N. Rithidech)
  10. Emami K, Hada M, Lacy S, Clement J, Rusek A, Cucinotta FA, Wu H. Apoptosis and micronuclei induction in human epithelial cells exposed to energetic carbon ions in the Bragg peak region. Adv Space Res. 2007;40(4):501-5. (PIs: F.A. Cucinotta, H. Wu)
  11. Leandro LJ, Szewczyk NJ, Benguría A, Herranz R, Laván D, Medina FJ, Gasset G, van Loon J, Conley CA, Marco R. Comparative analysis of Drosophila melanogaster and Caenorhabditis elegans gene expression experiments in the European Soyuz flights to the International Space Station. Adv Space Res. 2007;40(4):506-12. (PI: C.A. Conley) Note: ISS, Soyuz results.
  12. Chang PY, Bakke J, Puey A. Fractionated exposure of high energy iron ions has a sparing effect in vivo. Adv Space Res. 2007;40(4):568-75. (PI: P.Y. Chang)
  13. Rabin BM, Joseph JA, Shukitt-Hale B, Carey AN. Dietary modulation of the effects of exposure to 56Fe particles. Adv Space Res. 2007;40(4):576-80. (PI: B.M. Rabin)
  14. Mancusi D, Bertucci A, Gialanella G, Grossi G, Manti L, Pugliese M, Rusek A, Scampoli P, Sihver L, Durante M. Comparison of aluminum and lucite for shielding against 1 GeV protons. Adv Space Res. 2007;40(4):581-5.
  15. Maliev V, Popov D, Jones JA, Casey RC. Mechanism of action for anti-radiation vaccine in reducing the biological impact of high-dose gamma irradiation. Adv Space Res. 2007;40(4):586-90.

Other papers of interest:

  1. Aleksandrova NP, Donina ZhA, Tikhonov MA, Baranov VM. [The role of lung afferent system in respiratory control during head-down tilt] Ross Fiziol Zh Im I M Sechenova. 2007 Jun;93(6):670-7. Russian.
  2. Shibasaki M, Durand S, Davis SL, Cui J, Low DA, Keller DM, Crandall CG. Endogenous nitric oxide attenuates neutrally-mediated cutaneous vasoconstriction. J Physiol. 2007 Oct 18; [Epub ahead of print]
  3. Midura RJ, Vasanji A, Su X, Wang A, Midura SB, Gorski JP. Calcospherulites isolated from the mineralization front of bone induce the mineralization of type I collagen. Bone. 2007 Sep 6; [Epub ahead of print]
  4. Little JB. [Nontargeted effects of ionizing radiation: Implications for low-dose exposures] Radiats Biol Radioecol. 2007 May-Jun;47(3):262-72. Russian.
  5. Salnikov IV, Eidelman YA, Andreev SG. Biophysical modelling of DNA DSB repair following high LET irradiation. Radiats Biol Radioecol. 2007 May-Jun;47(3):292-6.
  6. Clarke AH, Haslwanter T. The orientation of Listing's Plane in microgravity. Vision Res. 2007 Oct 19; [Epub ahead of print] Note: Parabolic flight results.
  7. Romanov N, Fletcher G. Runners do not push off the ground but fall forwards via a gravitational torque. Sports Biomech. 2007 Sep;6(3):434-52.
  8. Li XG, Chen AD, Wang LF, Zheng HQ. [Analysis of tobacco regeneration plants from the protoplasts produced by electofusion in space] Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao. 2007 Oct;33(5):361-8. Chinese. Note: Chinese Shenzhou-4 results.
  9. Horneck G, Rabbow E. Mutagenesis by outer space parameters other than cosmic rays. Adv Space Res. 2007;40(4):445-54.
  10. Li Q. Biomedical research with heavy ions at the IMP accelerators. Adv Space Res. 2007;40(4):455-60.
  11. Yatagai F, Umebayashi Y, Suzuki M, Abe T, Suzuki H, Shimazu T, Ishioka N, Iwaki M, Honma M. Influence of low-dose and low-dose-rate ionizing radiation on mutation induction in human cells. Adv Space Res. 2007;40(4):470-3.
  12. Baumstark-Khan C, Rosendahl IM, Rink H. On the quality of mutations in mammalian cells induced by high LET radiations. Adv Space Res. 2007;40(4):474-82.
  13. Ruan W, Eastman PS, Cooke PA, Park JS, Chu JS, Gray JW, Li S, Chen FF. Nanobarcode gene expression monitoring system for potential miniaturized space applications. Adv Space Res. 2007;40(4):513-22.
  14. Li Y, Liu M, Cheng Z, Sun Y. Space environment induced mutations prefer to occur at polymorphic sites of rice genomes. Adv Space Res. 2007;40(4):523-7. Note: Chinese satellite JB-1 results.
  15. Yu X, Wu H, Wei LJ, Cheng ZL, Xin P, Huang CL, Zhang KP, Sun YQ. Characteristics of phenotype and genetic mutations in rice after spaceflight. Adv Space Res. 2007;40(4):528-34. Note: Chinese Shenzhou-3 results.
  16. Ma Y, Cheng Z, Wang W, Sun Y. Proteomic analysis of high yield rice variety mutated from spaceflight. Adv Space Res. 2007;40(4):535-9. Note: Chinese satellite JB-1 results.
  17. Cheng Z, Liu M, Zhang M, Hang X, Lei C, Sun Y. Transcriptomic analyses of space-induced rice mutants with enhanced susceptibility to rice blast. Adv Space Res. 2007;40(4):540-9. Note: Chinese satellite JB-1 results.
  18. Wang B, Murakami M, Eguchi-Kasai K, Nojima K, Shang Y, Tanaka K, Watanabe K, Fujita K, Moreno SG, Coffigny H, Hayata I. Effects of prenatal irradiation with accelerated heavy-ion beams on postnatal development in rats: III. Testicular development and breeding activity. Adv Space Res. 2007;40(4):550-62.
  19. Xie Y, Zhang H, Dang B, Bing T, Hao J, Guo H, Wang X. Early effects of carbon-ion irradiation on murine lymphocytes and thymocytes. Adv Space Res. 2007;40(4):563-7.

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