NASA Spaceline 4 January 2008 Current Space Life Science Awareness

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

1. Trappe SW, Creer A, Minchev K, Slivka D, Louis E, Luden N, Trappe TA. Human soleus single muscle fiber function with exercise or nutrition countermeasures during 60 days of bed rest. Am J Physiol Regul Integr Comp Physiol. 2007 Dec 19; [Epub ahead of print] (PI: S. Trappe) Note: From end of paper: "The fact that MHC I fibers from the vastus lateralis [previously reported research] and soleus muscle atrophy to a similar extent with long duration unloading, but respond differently to the same exercise loading program was an interesting and novel finding. These data suggest that unique and specific exercise regimens for the upper (vastus lateralis) and lower leg (soleus) may be necessary to protect human skeletal muscle during extended unloading periods."
2. Fitts RH. The cross-bridge cycle and skeletal muscle fatigue. J Appl Physiol. 2007 Dec 27; [Epub ahead of print] (PI: R.H. Fitts)
3. Simon JL, Michna S, Lewis JA, Rekow ED, Thompson VP, Smay JE, Yampolsky A, Parsons JR, Ricci JL. In vivo bone response to 3D periodic hydroxyapatite scaffolds assembled by direct ink writing. J Biomed Mater Res A. 2007 Dec 1;83(3):747-58. (PI: J.A. Lewis)
4. Uttayarat P, Chen M, Li M, Allen FD, Composto RJ, Lelkes PI. Microtopography and flow modulate the direction of endothelial cell migration. Am J Physiol Heart Circ Physiol. 2007 Dec 21; [Epub ahead of print] (PIs: P.I. Lelkes, D.M. Eckmann)
5. Soller BR, Ryan KL, Rickards CA, Cooke WH, Yang Y, Soyemi OO, Crookes BA, Heard SO, Convertino VA. Oxygen saturation determined from deep muscle, not thenar tissue, is an early indicator of central hypovolemia in humans. Crit Care Med. 2008 Jan;36(1):176-82. (PI: B.R. Soller)
6. Shuryak I, Sachs RK, Brenner DJ. Biophysical models of radiation bystander effects: 1. Spatial effects in three-dimensional tissues. Radiat Res. 2007 Dec;168(6):741-9. (PI: L. Hlatky/R.K. Sachs/NSCOR)
7. Groesser T, Chun E, Rydberg B. Relative biological effectiveness of high-energy iron ions for micronucleus formation at low doses. Radiat Res. 2007 Dec;168(6):675-82. (PIs: B. Rydberg, M.H. Barcellos-Hoff/B. Rydberg/NSCOR)
8. Zaidi FH, Hull JT, Peirson SN, Wulff K, Aeschbach D, Gooley JJ, Brainard GC, Gregory-Evans K, Rizzo JF 3rd, Czeisler CA, Foster RG, Moseley MJ, Lockley SW. Short-wavelength light sensitivity of circadian, pupillary, and visual awareness in humans lacking an outer retina. Curr Biol. 2007 Dec 18;17(24):2122-8. (PI: G.C. Brainard, C.A. Czeisler, R.G. Foster, S.W. Lockley) Note: This paper can be obtained online without charge.
9. Stevenson TO, Mercer KB, Cox EA, Szewczyk NJ, Conley CA, Hardin JD, Benian GM. unc-94 encodes a tropomodulin in Caenorhabditis elegans. J Mol Biol. 2007 Dec 7;374(4):936-50. Epub 2007 Oct 10.
10. Monshausen GB, Bibikova TN, Messerli MA, Shi C, Gilroy S. Oscillations in extracellular pH and reactive oxygen species modulate tip growth of Arabidopsis root hairs. Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20996-1001. Epub 2007 Dec 13. (PI: S. Gilroy) Note: This paper in listed on the cover of PNAS and is described in an accompanying commentary.
11. Aydogan S, Pekny JF, Orcun S. Effect of different waste recovery systems on the overall waste generation rates for an Advanced Life Support System. Int J Environ Pollut. 2007;29(1/2/3):232-53. (PI: C.A. Mitchell/J.F. Pekny/S. Orcun/NSCORT)
12. Pennell KG, Aronson AI, Blatchley ER 3rd. Phenotypic persistence and external shielding ultraviolet radiation inactivation kinetic model. J Appl Microbiol. 2007 Nov 20; [Epub ahead of print] (PI: C.A. Mitchell/E.R. Blatchley 3rd/NSCORT)

Other papers of interest:

1. Eckberg DL. Arterial baroreflexes and cardiovascular modeling. Cardiovasc Eng. 2007 Dec 15; [Epub ahead of print]
2. Mosso M, Schmid-Priscoveanu A, Straumann D, Baumgartner RW. Absence of gravity-dependent modulation of straight sinus flow velocity in healthy humans. Ultrasound Med Biol. 2007 Dec 19; [Epub ahead of print]
3. Hachiya T, Blaber AP, Saito M. Near-infrared spectroscopy provides an index of blood flow and vasoconstriction in calf skeletal muscle during LBNP. Acta Physiol (Oxf). 2007 Dec 19; [Epub ahead of print]
4. Gao F, Zhang LF, Huang WQ, Sun L. [Chronic blockade of angiotensin II type 1 receptor cannot completely prevent structural adaptation in vessels of simulated weightless rats] Sheng Li Xue Bao. 2007 Dec 25;59(6):821-30. Chinese. Note: This paper can be obtained online without charge.
5. Zhang L, Wang YY, Yu ZB. [Depressed responsiveness of cardiomyocytes to isoproterenol in simulated weightlessness rats] Sheng Li Xue Bao. 2007 Dec 25;59(6):845-50. Chinese. Note: This paper can be obtained online without charge.
6. Johnson WL, Jindrich DL, Roy RR, Edgerton VR. A three-dimensional model of the rat hindlimb: Musculoskeletal geometry and muscle moment arms. J Biomech. 2007 Nov 30; [Epub ahead of print]
7. Robling AG, Niziolek PJ, Baldridge LA, Condon KW, Allen MJ, Alam I, Mantila SM, Gluhak-Heinrich J, Bellido TM, Harris SE, Turner CH. Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin. J Biol Chem. 2007 Dec 17; [Epub ahead of print] Note: This paper can currently be obtained online without charge
8. Fachin AL, Mello SS, Sandrin-Garcia P, Junta CM, Donadi EA, Passos GA, Sakamoto-Hojo ET. Gene expression profiles in human lymphocytes irradiated in vitro with low doses of gamma rays. Radiat Res. 2007 Dec;168(6):650-65.
9. Tawn EJ, Whitehouse CA, De Ruyck K, Hodgson L, Vandenbulcke K, Thierens H. The characterization and transmissibility of chromosome aberrations induced in peripheral blood lymphocytes by in vitro alpha-particle radiation. Radiat Res. 2007 Dec;168(6):666-74.
10. Hamada N, Ni M, Funayama T, Sakashita T, Kobayashi Y. Temporally distinct response of irradiated normal human fibroblasts and their bystander cells to energetic heavy ions. Mutat Res. 2007 Nov 12; [Epub ahead of print]
11. Moeller R, Setlow P, Horneck G, Berger T, Reitz G, Rettberg P, Doherty AJ, Okayasu R, Nicholson WL. Role of the major small, acid-soluble spore proteins, spore specific and universal DNA repair mechanisms in the resistance of Bacillus subtilis spores to ionizing radiation from X-rays and high energy charged (HZE) particle bombardment. J Bacteriol. 2007 Nov 30; [Epub ahead of print]
12. Fukuhara C, Tosini G. Analysis of daily and circadian gene expression in the rat pineal gland. Neurosci Res. 2007 Nov 6; [Epub ahead of print]
13. Ishay JS, Barkay Z, Eliaz N, Plotkin M, Volynchik S, Bergman DJ. Gravity orientation in social wasp comb cells (Vespinae) and the possible role of embedded minerals. Naturwissenschaften. 2007 Dec 18; [Epub ahead of print]
14. Boettcher M, Jaeger M, Kirschbaum M, Mueller T, Schnelle T, Duschl C. Gravitation-driven stress-reduced cell handling. Anal Bioanal Chem. 2007 Dec 9; [Epub ahead of print]
15. Sun F, Zhang W, Hu H, Li B, Wang Y, Zhao Y, Li K, Liu M, Li X. Salt modulates gravity signaling pathway to regulate growth direction of primary roots in Arabidopsis thaliana. Plant Physiol. 2007 Nov 16; [Epub ahead of print]