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NASA Spaceline 5 May 2008 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Thursday, May 8, 2008

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Cohrs RJ, Mehta SK, Schmid DS, Gilden DH, Pierson DL. Asymptomatic reactivation and shed of infectious varicella zoster virus in astronauts. J Med Virol. 2008 Jun;80(6):1116-22. (PI: D.L. Pierson) Note: Space flight results.
  2. Fritton JC, Myers ER, Wright TM, van der Meulen MC. Bone mass is preserved and cancellous architecture altered due to cyclic loading of the mouse tibia after orchidectomy. J Bone Miner Res. 2008 May;23(5):663-71. (PI: J.C. Fritton, NASA Graduate Student Researcher Program)
  3. Higaki K, Choe SY, Löbenberg R, Welage LS, Amidon GL. Mechanistic understanding of time-dependent oral absorption based on gastric motor activity in humans. Eur J Pharm Biopharm. 2008 Mar 7. [Epub ahead of print] (PI: G.L. Amidon)
  4. Moyers MF. EDR-2(R) film response to charged particles. Phys Med Biol. 2008 May 21;53(10):N165-73. Epub 2008 Apr 18. (PI: M.F. Moyers) Note: Carbon and iron ion irradiations were performed at the NASA Space Radiation Laboratory at Brookhaven.
  5. Firestein R, Blander G, Michan S, Oberdoerffer P, Ogino S, Campbell J, Bhimavarapu A, Luikenhuis S, de Cabo R, Fuchs C, Hahn WC, Guarente LP, Sinclair DA. The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. PLoS ONE. 2008 Apr 16;3(4):e2020. (PI: P. Oberdoerffer, NSBRI Postdoctoral Fellowship Program) Note: This paper can be obtained online without charge.
  6. Gilroy S. Plant tropisms. Curr Biol. 2008 Apr 8;18(7):R275-7. (PI: S. Gilroy)
  7. Robinson JA, Thumm TL, Thomas DA. NASA utilization of the International Space Station and the Vision for Space Exploration. Acta Astronaut. 2007 Jun-Aug;61(1-6):176-84. Note: Limited ISS results presented.
  8. Carr CE, Newman DJ. Characterization of a lower-body exoskeleton for simulation of space-suited locomotion. Acta Astronaut. 2008 Feb-Mar;62(4-5):308-23.
  9. Grugel RN, Luz P, Smith G, Spivey R, Jeter L, Gillies D, Hua F, Anilkumar AV. Materials research conducted aboard the International Space Station: Facilities overview, operational procedures, and experimental outcomes. Acta Astronaut. 2008 Apr-May;62(8-9):491-8. Note: Limited ISS results presented.

Other papers of interest:

  1. Rinaldi C, Haddad F, Bodell PW, Qin AX, Jiang W, Baldwin KM. Intergenic bidirectional promoter and cooperative regulation of the IIx and IIb MHC genes in fast skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2008 Apr 23. [Epub ahead of print]
  2. Majewski M, Betz O, Ochsner PE, Liu F, Porter RM, Evans CH. Ex vivo adenoviral transfer of bone morphogenetic protein 12 (BMP-12) cDNA improves Achilles tendon healing in a rat model. Gene Ther. 2008 Apr 24. [Epub ahead of print]
  3. Christensen B, Dyrberg E, Aagaard P, Enehjelm S, Krogsgaard M, Kjaer M, Langberg H. Effects of long-term immobilization and recovery on human triceps surae and collagen turnover in the Achilles tendon in patients with healing ankle fracture. J Appl Physiol. 2008 Apr 10. [Epub ahead of print]
  4. Fink H, Helming M, Unterbuchner C, Lenz A, Neff F, Martyn JA, Blobner M. Systemic inflammatory response syndrome increases immobility-induced neuromuscular weakness. Crit Care Med. 2008 Mar;36(3):910-6.
  5. Skerry TM. The response of bone to mechanical loading and disuse: Fundamental principles and influences on osteoblast/osteocyte homeostasis. Arch Biochem Biophys. 2008 May 15;473(2):117-23. Epub 2008 Mar 4. Note: From abstract: "Fundamentally, if we accept that hypertrophy of bone in response to increased loading is a desirable occurrence, then disuse is not a pathological process, but simply the corollary of adaptation to increased loads." This paper and the following paper are from a special issue on bone remodeling.
  6. Civitelli R. Cell-cell communication in the osteoblast/osteocyte lineage. Arch Biochem Biophys. 2008 May 15;473(2):188-92. Epub 2008 Apr 11.
  7. Jonas M, Huang H, Kamm RD, So PT. Fast fluorescence laser tracking microrheometry II: Quantitative studies of cytoskeletal mechanotransduction. Biophys J. 2008 Apr 18. [Epub ahead of print] Note: This paper can currently be obtained online without charge.
  8. Jonas M, Huang H, Kamm RD, So PT. Fast fluorescence laser tracking microrheometry. I: Instrument development. Biophys J. 2008 Feb 15;94(4):1459-69. Epub 2007 Oct 26.
  9. Niemelä TH, Kiviniemi AM, Hautala AJ, Salmi JA, Linnamo V, Tulppo MP. Recovery pattern of baroreflex sensitivity after exercise. Med Sci Sports Exerc. 2008 May;40(5):864-70.
  10. Robertson D. The pathophysiology and diagnosis of orthostatic hypotension. Clin Auton Res. 2008 Mar;18 Suppl 1:2-7. Epub 2008 Mar 27.
  11. Yamakawa N, Takahashi A, Mori E, Imai Y, Furusawa Y, Ohnishi K, Kirita T, Ohnishi T. High LET radiation enhances apoptosis in mutated p53 cancer cells through caspase-9 activation. Cancer Sci. 2008 Apr 16. [Epub ahead of print]
  12. Lewis RF, Haburcakova C, Merfeld DM. Roll tilt psychophysics in rhesus monkeys during vestibular and visual stimulation. J Neurophysiol. 2008 Apr 16. [Epub ahead of print]
  13. Goddard M, Zheng Y, Darlington CL, Smith PF. Locomotor and exploratory behavior in the rat following bilateral vestibular deafferentation. Behav Neurosci. 2008 Apr;122(2):448-59.
  14. Driss-Ecole D, Legué V, Carnero-Diaz E, Perbal G. Gravisensitivity and automorphogenesis of lentil seedling roots grown on board the International Space Station. Physiol Plant. 2008 Apr 18. [Epub ahead of print] Note: ISS results.
  15. Wang C, Zhuang F. [(Possible) molecular mechanism of cells in gravisensing] Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2008 Feb;25(1):227-30. Chinese.
  16. Simone L, Bartolomucci A, Palanza P, Parmigiani S. On-ground housing in “Mice Drawer System” (MDS) cage affects locomotor behaviour but not anxiety in male mice. Acta Astronaut. 2008 Mar-Apr;62(6-7):453-61. Note: This is a ground test of housing for mice that is planned for use on ISS.
  17. De Micco V, Aronne G. Biometric anatomy of seedlings developed onboard of Foton-M2 in an automatic system supporting growth. Acta Astronaut. 2008 Apr-May;62(8-9):505-13. Note: Foton-M2 results.

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