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NASA Spaceline 9 May 2008 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Friday, May 16, 2008

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Sauder CL, Leonard TO, Ray CA. Greater sensitivity of the vestibulosympathetic reflex in the upright posture in humans. J Appl Physiol. 2008 May 1. [Epub ahead of print] (PI: C.A. Ray)
  2. Mazzatti DJ, Smith MA, Oita RC, Lim FL, White AJ, Reid MB. Muscle unloading-induced metabolic remodelling is associated with acute alterations in PPAR{delta} and UCP-3 expression. Physiol Genomics. 2008 Apr 29. [Epub ahead of print] (PI: M.B. Reid)
  3. Durante M, Cucinotta FA. Heavy ion carcinogenesis and human space exploration. Nat Rev Cancer. 2008 May 2. [Epub ahead of print] (PI: F.A. Cucinotta) Note: This Perspective is a clear and readable overview of the space radiation problem.
  4. Vlkolinskı R, Krucker T, Nelson GA, Obenaus A. (56)Fe-particle radiation reduces neuronal output and attenuates lipopolysaccharide-induced inhibition of long-term potentiation in the mouse hippocampus. Radiat Res. 2008 May;169(5):523-30. (PI: G.A. Nelson/T. Krucker/A. Obenaus/NSCOR)
  5. Dingfelder M, Ritchie RH, Turner JE, Friedland W, Paretzke HG, Hamm RN. Comparisons of calculations with PARTRAC and NOREC: Transport of electrons in liquid water. Radiat Res. 2008 May;169(5):584-94. (PI: M. Dingfelder)
  6. Ding LH, Xie Y, Park S, Xiao G, Story MD. Enhanced identification and biological validation of differential gene expression via Illumina whole-genome expression arrays through the use of the model-based background correction methodology. Nucleic Acids Res. 2008 May 1. [Epub ahead of print] (PIs: R.L. Ullrich/M.D. Story/NSCOR; J.D. Minna/M.D. Story/NSCOR) Note: This paper can be obtained online without charge.
  7. Agarwal M, Pandita S, Hunt CR, Gupta A, Yue X, Khan S, Pandita RK, Pratt D, Shay JW, Taylor JS, Pandita TK. Inhibition of telomerase activity enhances hyperthermia-mediated radiosensitization. Cancer Res. 2008 May 1;68(9):3370-8. (PI: J.D. Minna/J.W. Shay/NSCOR)
  8. Vujovic N, Davidson AJ, Menaker M. Sympathetic input modulates, but does not determine, phase of peripheral circadian oscillators. Am J Physiol Regul Integr Comp Physiol. 2008 Apr 23. [Epub ahead of print] (PI: M. Menaker)
  9. Li JJ, Ouellette AL, Giovangrandi L, Cooper DE, Ricco AJ, Kovacs GT. Optical scanner for immunoassays with up-converting phosphorescent labels. IEEE Trans Biomed Eng. 2008 May;55(5):1560-71.

Other papers of interest:

  1. Okumura S, Tsunematsu T, Bai Y, Jiao Q, Ono S, Suzuki S, Kurotani R, Sato M, Minamisawa S, Umemura S, Ishikawa Y. Type 5 adenylyl cyclase plays a major role in stabilizing heart rate in response to microgravity induced by parabolic flight. J Appl Physiol. 2008 May 1. [Epub ahead of print] Note: Parabolic flight results.
  2. Arora P, Husom AD, Ferrington DA, Thompson LV. Age-dependent effects of treadmill exercise during a period of inactivity. Exp Gerontol. 2008 Mar 20. [Epub ahead of print]
  3. Balásházy I, Hofmann W, Farkas A, Madas BG. Three-dimensional model for aerosol transport and deposition in expanding and contracting alveoli. Inhal Toxicol. 2008 Apr;20(6):611-21.
  4. Gundersen K, Bruusgaard JC. Nuclear domains during muscle atrophy: Nuclei lost or paradigm lost? J Physiol. 2008 Apr 25. [Epub ahead of print]
  5. Suetta C, Andersen JL, Dalgas U, Berget J, Koskinen SO, Aagaard P, Magnusson SP, Kjaer M. Resistance training induces qualitative changes in muscle morphology, muscle architecture and muscle function in elderly postoperative patients. J Appl Physiol. 2008 Apr 17. [Epub ahead of print]
  6. Kermani HR, Soroush Z. Effect of long-term axial spinal unloading on vertebral body height in adult thoracolumbar spine. Eur Spine J. 2008 Apr 18. [Epub ahead of print]
  7. Lee SE, Chunsrivirot S, Kamm RD, Mofrad MR. Molecular dynamics study of talin-vinculin binding. Biophys J. 2008 Apr 11. [Epub ahead of print] Note: This paper can currently be obtained online without charge.
  8. Li H, Liu N, Rajendran GK, Gernon TJ, Rockhill JK, Schwartz JL, Gu Y. A role for endogenous and radiation-induced DNA double-strand breaks in p53-dependent apoptosis during cortical neurogenesis. Radiat Res. 2008 May;169(5):513-22.
  9. Bertho JM, Roy L, Souidi M, Benderitter M, Gueguen Y, Lataillade JJ, Prat M, Fagot T, De Revel T, Gourmelon P. New biological indicators to evaluate and monitor radiation-induced damage: An accident case report. Radiat Res. 2008 May;169(5):543-50.
  10. Wilkins RC, Romm H, Kao TC, Awa AA, Yoshida MA, Livingston GK, Jenkins MS, Oestreicher U, Pellmar TC, Prasanna PG. Interlaboratory comparison of the dicentric chromosome assay for radiation biodosimetry in mass casualty events. Radiat Res. 2008 May;169(5):551-60.
  11. Hamada N, Hara T, Omura-Minamisawa M, Funayama T, Sakashita T, Sora S, Nakano T, Kobayashi Y. The survival of heavy ion-irradiated Bcl-2 overexpressing radioresistant tumor cells and their progeny. Cancer Lett. 2008 Apr 29. [Epub ahead of print]
  12. Shojaku H, Watanabe Y, Tsubota M, Katayama N. Evaluation of the vestibular evoked myogenic potential during parabolic flight in humans. Exp Brain Res. 2008 May;187(3):477-81. Epub 2008 Apr 29. Note: Parabolic flight results.
  13. Lawrence JE, Ray CA, Carter JR. Vestibulosympathetic reflex during the early follicular and mid-luteal phases of the menstrual cycle. Am J Physiol Endocrinol Metab. 2008 Apr 8. [Epub ahead of print]
  14. Hahn H, Müller M, Löwenheim H. Whole organ culture of the postnatal sensory inner ear in simulated microgravity. J Neurosci Methods. 2008 Jun 15;171(1):60-71. Epub 2008 Feb 13. Note: In vitro culture of excised whole inner ear organs of mice was achieved with the use of the rotary cell culture bioreactor. According to the authors, "The successful postnatal culture of the intact whole inner ear organ has not been previously achieved."
  15. Emin N, Koç A, Durkut S, Elçin AE, Elçin YM. Engineering of rat articular cartilage on porous sponges: Effects of TGF-beta 1 and microgravity bioreactor culture. Artif Cells Blood Substit Immobil Biotechnol. 2008;36(2):123-37.
  16. Zhou F, Li DL, Li Y, Xing L, Ye SM, Chen H. [Study on a non-invasive wide-range blood oxygen saturation detecting method and its instrument design] Zhongguo Yi Liao Qi Xie Za Zhi. 2008 Jan;32(1):23-5. Chinese.
  17. Qiu D, Wilson IW, Gan S, Washusen R, Moran GF, Southerton SG. Gene expression in Eucalyptus branch wood with marked variation in cellulose microfibril orientation and lacking G-layers. New Phytol. 2008 Apr 14. [Epub ahead of print]

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