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NASA Spaceline 11 July 2008 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Monday, August 11, 2008

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. O'Donnell PM, Orshal JM, Sen D, Sonnenfeld G, Aviles HO. Effects of exposure of mice to hindlimb unloading on leukocyte subsets and sympathetic nervous system activity. Stress. 2008 Jun 18:1. [Epub ahead of print] (PI: G.D. Sonnenfeld)
  2. Sudo H, Garbe J, Stampfer MR, Barcellos-Hoff MH, Kronenberg A. Karyotypic instability and centrosome aberrations in the progeny of finite life-span human mammary epithelial cells exposed to sparsely or densely ionizing radiation. Radiat Res. 2008 Jul;170(1):23-32. (PI: M.H. Barcellos-Hoff/A. Kronenberg/NSCOR)
  3. Cucinotta FA, Kim MH, Willingham V, George KA. Physical and biological organ dosimetry analysis for International Space Station astronauts. Radiat Res. 2008 Jul;170(1):127-38. (PI: F.A. Cucinotta) Note: ISS, Mir, Shuttle results. This paper compiles data from numerous flights.
  4. Burns FJ, Rossman T, Vega K, Uddin A, Vogt S, Lai B, Reeder RJ. Mechanism of selenium-induced inhibition of arsenic-enhanced UVR carcinogenesis in mice. Environ Health Perspect. 2008 Jun;116(6):703-8. (PI: F.J. Burns) Note: This paper can be obtained online without charge via PubMed Central or at the publisher's site.
  5. Clement JQ, Lacy SM, Wilson BL. Gene expression profiling of human epidermal keratinocytes in simulated microgravity and recovery cultures. Genomics Proteomics Bioinformatics. 2008 Feb;6(1):8-28. Note: This paper and the following two papers and two papers in the Other section constitute an issue of this journal on the topic of genomics in the space life sciences. A preface is here. These papers can be obtained online without charge if accessed via the publisher's site Table of Contents. To do this, go to the publisher's site abstract via the PubMed link to Elsevier, then click on the volume and issue on the left side. Some papers are very slow to download.
  6. Liu Y, Wang E. Transcriptional analysis of normal human fibroblast responses to microgravity stress. Genomics Proteomics Bioinformatics. 2008 Feb;6(1):29-41. (PI: E. Wang) Note: STS-93 results. This paper can be obtained online without charge if accessed via the publisher's site Table of Contents.
  7. Altenburg SD, Nielsen-Preiss SM, Hyman LE. Increased filamentous growth of Candida albicans in simulated microgravity. Genomics Proteomics Bioinformatics. 2008 Feb;6(1):42-50. (PI: L.E. Hyman) Note: This paper can be obtained online without charge if accessed via the publisher's site Table of Contents.
  8. Yao J, Chang C, Salmi ML, Hung YS, Loraine A, Roux SJ. Genome-scale cluster analysis of replicated microarrays using shrinkage correlation coefficient. BMC Bioinformatics. 2008 Jun 18;9:288. [Epub ahead of print] (PI: S.J. Roux) Note: This paper can be obtained online without charge.
  9. Kumar NS, Stevens MH, Kiss JZ. Plastid movement in statocytes of the arg1 (altered response to gravity) mutant. Am. J. Bot. 2008 Feb;95(2):177-84. (PI: J.Z. Kiss)

Other papers of interest:

  1. Edgell H, Kaufman S. Effect of hindlimb unloading on salt and water intake and output in male and female rats. Med Sci Sports Exerc. 2008 Jul;40(7):1249-54.
  2. Koyama T, Kimura C, Hayashi M, Watanabe M, Karashima Y, Oike M. Hypergravity induces ATP release and actin reorganization via tyrosine phosphorylation and RhoA activation in bovine endothelial cells. Pflugers Arch. 2008 Jul 2. [Epub ahead of print]
  3. Bogomolov VV, Goncharov IB, Bogatova RI, Kovachevich IV, Alferova IV. [Medical provisions for non-career cosmonauts on short-duration flights to the International Space Station] Aviakosm Ekolog Med. 2008 Jan-Feb;42(1):15-9. Russian. Note: ISS results.
  4. Zaichkina SI, Rozanova OM, Akhmadieva AK, Aptikaeva GF, Smirnova EN, Sorokina SS, Romanchenko SP, Vakhrusheva OA, Peleshko VN. [Peculiar effects of low doses of high LET radiation on mice] Aviakosm Ekolog Med. 2008 Jan-Feb;42(1):22-7. Russian.
  5. Kaplansky AS, Durnova GN, Orlov OI, Ilyin EA. [Histological study of the visceral organs of Mongolian gerbil Meriones unguiculatus as a subject in spaceflight experiments] Aviakosm Ekolog Med. 2008 Jan-Feb;42(1):28-31. Russian.
  6. Egorov AD, Kozlovskaya IB, Shipov AA. [Quantitative evaluation of the effectiveness of physical contermeasures against motor disorders in long-duration space flight] Aviakosm Ekolog Med. 2008 Jan-Feb;42(1):54-6. Russian. Note: Space flight results.
  7. Matyushkin DP. [Inquiry into potential influence of the spaceflight factors on cerebral neurons and neural network (theoretical treatment)] Aviakosm Ekolog Med. 2008 Jan-Feb;42(1):63-6. Russian.
  8. Tong HY, Hu SM, Zhou P, Fu Q, Yang J, Gao XM, Zhang JJ, Zhong GS. [Effects of Chinese compound prescription on bone metabolism of weightlessness rats simulated by suspension] Zhongguo Zhong Yao Za Zhi. 2008 Apr;33(7):797-801. Chinese.
  9. West JB. Special issue: Genomics and high altitude. High Alt Med Biol. 2008 Summer;9(2):103. Note: This editorial introduces a special issue of this journal dealing with genomics and high altitude. The editorial is available online without charge.
  10. Tyburski JB, Patterson AD, Krausz KW, Slavík J, Fornace AJ, Gonzalez FJ, Idle JR. Radiation metabolomics. 1. Identification of minimally invasive urine biomarkers for gamma-radiation exposure in mice. Radiat Res. 2008 Jul;170(1):1-14. Note: This paper can be obtained online without charge via PubMed Central.
  11. Balagurumoorthy P, Chen K, Adelstein SJ, Kassis AI. Auger electron-induced double-strand breaks depend on DNA topology. Radiat Res. 2008 Jul;170(1):70-82.
  12. Hida K, Nomura Y, Igarashi M, Sudoh M, Tada A, Sugiyama Y, Shigihara S, Ikeda M. Optokinetic nystagmus and after-nystagmus during a 6 hour bedrest study. Acta Otolaryngol. 2008 Jul;128(7):761-7.
  13. Mahboobin A, Loughlin PJ, Redfern MS, Anderson SO, Atkeson CG, Hodgins JK. Sensory adaptation in human balance control: Lessons for biomimetic robotic bipeds. Neural Netw. 2008 May;21(4):621-7. Epub 2008 May 14. Note: This paper is part of a special issue: "Robotics and Neuroscience."
  14. Zhang P, Hamamura K, Yokota H. A brief review of bone adaptation to unloading. Genomics Proteomics Bioinformatics. 2008 Feb;6(1):4-7. Note: This paper can be obtained online without charge if accessed via the publisher's site Table of Contents.
  15. Lu WH, Wang XZ, Zheng Q, Guan SH, Xin P, Sun YQ. Diversity and stability study on rice mutants induced in space environment. Genomics Proteomics Bioinformatics. 2008 Feb;6(1):51-60. Note: This paper reports on later generations of rice seeds previously flown on a Chinese recoverable satellite. The paper can be obtained online without charge if accessed via the publisher's site Table of Contents.
  16. Kim SM, Lee SH, Suh KY. Cell research with physically modified microfluidic channels: A review. Lab Chip. 2008 Jul;8(7):1015-23. Epub 2008 May 15.
  17. Farges B, Poughon L, Creuly C, Cornet JF, Dussap CG, Lasseur C. Dynamic aspects and controllability of the MELiSSA Project: A bioregenerative system to provide life support in space. Appl Biochem Biotechnol. 2008 Jul 1. [Epub ahead of print]
  18. Ushakova SA, Zolotukhin IG, Tikhomirov AA, Tikhomirova NA, Kudenko YA, Gribovskaya IV, Balnokin Y, Gros JB. Some methods for human liquid and solid waste utilization in bioregenerative life-support systems. Appl Biochem Biotechnol. 2008 Jun 26. [Epub ahead of print]

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