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NASA Spaceline 22 August 2008 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Friday, September 12, 2008

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Tse KY, Macias BR, Meyer RS, Hargens AR. Heritability of bone density: Regional and gender differences in monozygotic twins. J Orthop Res. 2008 Aug 6. [Epub ahead of print] (PI: A.R. Hargens)
  2. Hagelstrom RT, Askin KF, Williams AJ, Ramaiah L, Desaintes C, Goodwin EH, Ullrich RL, Bailey SM. DNA-PKcs and ATM influence generation of ionizing radiation-induced bystander signals. Oncogene. 2008 Aug 4. [Epub ahead of print] (PI: S.M. Bailey)
  3. Berghella L, De Angelis L, De Buysscher T, Mortazavi A, Biressi S, Forcales SV, Sirabella D, Cossu G, Wold BJ. A highly conserved molecular switch binds MSY-3 to regulate myogenin repression in postnatal muscle. Genes Dev. 2008 Aug 1;22(15):2125-38. (PI: B.J. Wold)
  4. Zhuang F, Horneck G, Gerzer R. The 16th IAA Humans in Space Symposium 2007 in Beijing, China. Acta Astronaut. 2008 Oct-Nov;63(7-10):695-6. Note: The following 18 papers and 24 papers in the Other section derive from the 16th IAA Humans in Space Symposium, held in Beijing, China from May 20-24, 2007. The remaining 17 papers in this issue, on astrobiology and life support topics, are not included in this list and can be seen in the Table of Contents (#40-56) at the publisher's site. The papers were organized in this issue within the following sections: Space Physiology; Space Psychology; Radiation Health Issues; Cell and Animal Physiology; Exploration and Habitation; and Politics, Operations, and Education.
  5. Layne CS, Nguyen K, Forth K. Muscle contractions in response to foot stimulation as an inflight countermeasure. Acta Astronaut. 2008 Oct-Nov;63(7-10):714-21.
  6. Summers R, Coleman T, Steven P [Platts S is correct], Martin D. Systems analysis of the mechanisms of cardiac diastolic function changes after microgravity exposure. Acta Astronaut. 2008 Oct-Nov;63(7-10):722-6. Note: Shuttle results.
  7. Scheuring R, Conkin J, Jones JA, Gernhardt ML. Risk assessment of physiological effects of atmospheric composition and pressure in Constellation vehicles. Acta Astronaut. 2008 Oct-Nov;63(7-10):727-39.
  8. Summers R, Coleman T, Meck J. Development of the Digital Astronaut Project for the analysis of the mechanisms of physiologic adaptation to microgravity: Validation of the cardiovascular system module. Acta Astronaut. 2008 Oct-Nov;63(7-10):758-62.
  9. Jones JA, Hoffman RB, Buckland DA, Harvey CM, Bowen CK, Hudy CE, Strauss S, Novak J, Gernhardt ML. The use of an extended ventilation tube as a countermeasure for EVA-associated upper extremity medical issues. Acta Astronaut. 2008 Oct-Nov;63(7-10):763-8.
  10. McPhee JC, White RJ. Advantages of international cooperation in space life sciences research. Acta Astronaut. 2008 Oct-Nov;63(7-10):776-82.
  11. Hienz RD, Brady JV, Hursh SR, Gasior ED, Spence KR, Emurian HH. Effects of incentives on psychosocial performances in simulated space-dwelling groups. Acta Astronaut. 2008 Oct-Nov;63(7-10):800-10. (PI: J.V. Brady)
  12. Kanas N, Gushin V, Yusupova A. Problems and possibilities of astronauts—Ground communication content analysis validity check. Acta Astronaut. 2008 Oct-Nov;63(7-10):822-7. (PI: N. Kanas) Note: ISS results.
  13. Clément G, Lathan C, Lockerd A. Perception of depth in microgravity during parabolic flight. Acta Astronaut. 2008 Oct-Nov;63(7-10):828-32. (PI: C. Lathan) Note: Parabolic flight results.
  14. Mollicone DJ, Van Dongen HP, Rogers NL, Dinges DF. Response surface mapping of neurobehavioral performance: Testing the feasibility of split sleep schedules for space operations. Acta Astronaut. 2008 Oct-Nov;63(7-10):833-40. (PI: D.F. Dinges)
  15. Aoki H, Oman CM, Buckland DA, Natapoff A. Desktop-VR system for preflight 3D navigation training. Acta Astronaut. 2008 Oct-Nov;63(7-10):841-7. (PIs: H. Aoki, NSBRI Postdoctoral Fellowship Program; C.M. Oman)
  16. Zhou D, O’Sullivan D, Semones E, Zapp N, Johnson S, Weyland M. Radiation dosimetry for high LET particles in low Earth orbit. Acta Astronaut. 2008 Oct-Nov;63(7-10):855-64. Note: ISS and Shuttle results.
  17. Sihver L, Mancusi D, Niita K, Sato T, Townsend L, Farmer C, Pinsky L, Ferrari A, Cerutti F, Gomes I. Benchmarking of calculated projectile fragmentation cross-sections using the 3-D, MC codes PHITS, FLUKA, HETC-HEDS, MCNPX_HI, and NUCFRG2. Acta Astronaut. 2008 Oct-Nov;63(7-10):865-77. (PI: L. Townsend)
  18. Scheuring RA, Jones JA, Novak JD, Polk JD, Gillis DB, Schmid J, Duncan JM, Davis JR. The Apollo Medical Operations Project: Recommendations to improve crew health and performance for future exploration missions and lunar surface operations. Acta Astronaut. 2008 Oct-Nov;63(7-10):980-7. Note: Project included review of results and experiences of Apollo medical operations.
  19. Davis JR, Fogarty JA, Richard EE. Human health and performance risk management—An approach for exploration missions. Acta Astronaut. 2008 Oct-Nov;63(7-10):988-95.
  20. Khan-Mayberry N. The lunar environment: Determining the health effects of exposure to moon dusts. Acta Astronaut. 2008 Oct-Nov;63(7-10):1006-14.
  21. Duncan JM, Bogomolov VV, Castrucci F, Koike Y, Comtois JM, Sargsyan AE. Organization and management of the International Space Station (ISS) multilateral medical operations. Acta Astronaut. 2008 Oct-Nov;63(7-10):1137-47.
  22. MacLeish MY, Thomson WA, Moreno N, Smith RB, Houston CW, Sognier M, Coulter G, Vogt GL. Education for the journey to the Moon, Mars, and beyond. Acta Astronaut. 2008 Oct-Nov;63(7-10):1158-67. (PI: W.A. Thomson/M.Y. MacLeish)

Other papers of interest:

  1. Zhang LF, Cheng JH, Liu X, Wang S, Liu Y, Lu HB, Ma J. Cardiovascular changes of conscious rats after simulated microgravity with and without daily -Gx gravitation. J Appl Physiol. 2008 Aug 14. [Epub ahead of print] Note: Gravity used as a countermeasure.
  2. Frigeri A, Iacobas DA, Iacobas S, Nicchia GP, Desaphy JF, Camerino DC, Svelto M, Spray DC. Effect of microgravity on gene expression in mouse brain. Exp Brain Res. 2008 Aug 14. [Epub ahead of print]
  3. Zhu Y, Fan X, Li X, Wu S, Zhang H, Yu L. Effect of hindlimb unloading on resting intracellular calcium in intrafusal fibers and ramp-and-hold stretches evoked responsiveness of soleus muscle spindles in conscious rats. Neurosci Lett. 2008 Sep 19;442(3):169-73. Epub 2008 Apr 26.
  4. Moriggi M, Cassano P, Vasso M, Capitanio D, Fania C, Musicco C, Pesce V, Gadaleta MN, Gelfi C. A DIGE approach for the assessment of rat soleus muscle changes during unloading: Effect of acetyl-L-carnitine supplementation. Proteomics. 2008 Aug 6. [Epub ahead of print]
  5. Ghosh K, Thodeti CK, Dudley AC, Mammoto A, Klagsbrun M, Ingber DE. Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11305-10. Epub 2008 Aug 6.
  6. Rykova MP, Antropova EN, Larina IM, Morukov BV. Humoral and cellular immunity in cosmonauts after the ISS missions. Acta Astronaut. 2008 Oct-Nov;63(7-10):697-705. Note: ISS results.
  7. Tarakina MV, Turtikova OV, Nemirovskaya TL, Kokontcev AA, Shenkman BS. Muscle progenitor cells proliferation doesn’t sufficiently contribute to maintaining stretched soleus muscle mass during gravitational unloading. Acta Astronaut. 2008 Oct-Nov;63(7-10):706-13.
  8. Schroeder C, Strempel S, Boese A, Hemmersbach R, Tank J, Luft FC, Jordan J. Norepinephrine transporter function and tolerance to hypergravitational stress: A pilot study. Acta Astronaut. 2008 Oct-Nov;63(7-10):740-4.
  9. Souvestre PA, Blaber AP, Landrock CK. Space motion sickness: The sensory motor controls and cardiovascular correlation. Acta Astronaut. 2008 Oct-Nov;63(7-10):745-57.
  10. Cohen LY, Vernon M, Bergeron MG. New molecular technologies against infectious diseases during space flight. Acta Astronaut. 2008 Oct-Nov;63(7-10):769-75.
  11. Clément G, Bukley A. Research recommendations of the ESA Topical Team on Artificial Gravity. Acta Astronaut. 2008 Oct-Nov;63(7-10):783-90.
  12. Johannes B, Salnitski V, Soll H, Rauch M, Hoermann HJ. De-individualized psychophysiological strain assessment during a flight simulation test—Validation of a space methodology. Acta Astronaut. 2008 Oct-Nov;63(7-10):791-9.
  13. Hu HM, Ding L, Chen SP, Yang CX, Yuan XG. Study on functional relationships between ergonomics indexes of manual performance. Acta Astronaut. 2008 Oct-Nov;63(7-10):811-21.
  14. Hoermann HJ, Johannes B, Salnitski VP. The “Digital Friend”: A knowledge-based decision support system for space crews. Acta Astronaut. 2008 Oct-Nov;63(7-10):848-54.
  15. Hirn A, Apáthy I, Bodnár L, Csoke A, Deme S, Pázmándi T. Development of a complex instrument measuring dose in the Van Allen belts. Acta Astronaut. 2008 Oct-Nov;63(7-10):878-85.
  16. Sihver L. Physics and biophysics experiments needed for improved risk assessment in space. Acta Astronaut. 2008 Oct-Nov;63(7-10):886-98.
  17. Masini MA, Strollo F, Ricci F, Prato P, Uva BM. Low gravity and integrins in cultured glial cells. Acta Astronaut. 2008 Oct-Nov;63(7-10):899-905.
  18. Hellweg CE, Baumstark-Khan C, Spitta L, Thelen M, Arenz A, Franz M, Schulze-Varnholt D, Berger T, Reitz G. The space experiment CERASP: Definition of a space-suited radiation source and growth conditions for human cells. Acta Astronaut. 2008 Oct-Nov;63(7-10):906-14.
  19. He J, Zhang X, Gao Y, Li S, Sun Y. Effects of altered gravity on the cell cycle, actin cytoskeleton and proteome in Physarum polycephalum. Acta Astronaut. 2008 Oct-Nov;63(7-10):915-22.
  20. Yang C, Wei D, Zhuang FY. The force induced by organelles’ weight in the microfilament is in the range of 0.1–1 pN. Acta Astronaut. 2008 Oct-Nov;63(7-10):923-8.
  21. Qian A, Zhang W, Weng Y, Tian Z, Di S, Yang P, Yin D, Hu L, Wang Z, Xu H, Shang P. Gravitational environment produced by a superconducting magnet affects osteoblast morphology and functions. Acta Astronaut. 2008 Oct-Nov;63(7-10):929-46.
  22. Qian A, Zhang W, Xie L, Weng Y, Yang P, Wang Z, Hu L, Xu H, Tian Z, Shang P. Simulated weightlessness alters biological characteristics of human breast cancer cell line MCF-7. Acta Astronaut. 2008 Oct-Nov;63(7-10):947-58.
  23. Yao YJ, Sun HP, Yue Y, Sun XQ, Wu XY. Changes of loading tensile force–stretch relationships of rabbit mesenteric vein after 21 days of head-down rest. Acta Astronaut. 2008 Oct-Nov;63(7-10):959-67.
  24. Sun L, Gan B, Fan Y, Xie T, Hu Q, Zhuang F. Simulated microgravity alters multipotential differentiation of rat mesenchymal stem cells in association with reduced telomerase activity. Acta Astronaut. 2008 Oct-Nov;63(7-10):968-73.
  25. Zhou Y, Tan X, Zhu BA, Qi MD, Ding SL. Abnormal pituitary-gonadal axis may be responsible for rat decreased testicular function under simulated microgravity. Acta Astronaut. 2008 Oct-Nov;63(7-10):974-9.
  26. Haidegger T, Benyo Z. Surgical robotic support for long duration space missions. Acta Astronaut. 2008 Oct-Nov;63(7-10):996-1005.
  27. Oei I, Mirra C. Europe's human research experiments integration on the International Space Station. Acta Astronaut. 2008 Oct-Nov;63(7-10):1126-36.
  28. Buckley N, Johnson-Green P, Lefebvre L. Worms to astronauts: Canadian Space Agency approach to life sciences in support of exploration. Acta Astronaut. 2008 Oct-Nov;63(7-10):1148-51.
  29. Podhajsky S, de Negueruela C. From dreams to reality: 20 years of ISU Team Projects. Acta Astronaut. 2008 Oct-Nov;63(7-10):1152-7.

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