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NASA Spaceline 24 October 2008 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Wednesday, November 19, 2008

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Conkin J, Wessel JH 3rd. Critique of the equivalent air altitude model. Aviat Space Environ Med. 2008 Oct;79(10):975-82.
  2. Williams R. Space medicine at NASA Headquarters (Office of the Chief Health and Medical Officer). Aviat Space Environ Med. 2008 Oct;79(10):1001. Note: This article, which is the Space Medicine Association News topic for this issue of this journal, can be accessed online without cost.
  3. Solaimanzadeh I, Schlegel TT, Feiveson AH, Greco EC, DePalma JL, Starc V, Marthol H, Tutaj M, Buechner S, Axelrod FB, Hilz MJ. Advanced electrocardiographic predictors of mortality in familial dysautonomia. Auton Neurosci. 2008 Oct 11. [Epub ahead of print] (PIs: I. Solaimanzadeh, NSBRI Student Internship Program; T.T. Schlegel)
  4. Maxwell CA, Fleisch MC, Costes SV, Erickson AC, Boissière A, Gupta R, Ravani SA, Parvin B, Barcellos-Hoff MH. Targeted and nontargeted effects of ionizing radiation that impact genomic instability. Cancer Res. 2008 Oct 15;68(20):8304-11. (PI: M.H. Barcellos-Hoff/S.V. Costes/B. Parvin/NSCOR) Note: From abstract: "Together, these studies show that radiation deregulates centrosome stability, which underlies genomic instability in normal human epithelial cells, and that this can be opposed by radiation-induced TGFbeta signaling."
  5. Dziegielewski J, Baulch JE, Goetz W, Coleman MC, Spitz DR, Murley JS, Grdina DJ, Morgan WF. WR-1065, the active metabolite of amifostine, mitigates radiation-induced delayed genomic instability. Free Radic Biol Med. 2008 Sep 18. [Epub ahead of print] (PI: W.F. Morgan)
  6. Mulavara AP, Cohen HS, Bloomberg JJ. Critical features of training that facilitate adaptive generalization of over ground locomotion. Gait Posture. 2008 Oct 4. [Epub ahead of print] (PI: J.J. Bloomberg)
  7. MacNeilage PR, Ganesan N, Angelaki DE. Computational approaches to spatial orientation: From transfer functions to dynamic Bayesian inference. J Neurophysiol. 2008 Oct 8. [Epub ahead of print] (PI: P.R. MacNeilage, NSBRI Postdoctoral Fellowship Program)
  8. Karmali F, Shelhamer M. Compensating for camera translation in video eye-movement recordings by tracking a representative landmark selected automatically by a genetic algorithm. J Neurosci Methods. 2008 Sep 17. [Epub ahead of print] (PI: M. Shelhamer)
  9. Brainard GC, Sliney D, Hanifin JP, Glickman G, Byrne B, Greeson JM, Jasser S, Gerner E, Rollag MD. Sensitivity of the human circadian system to short-wavelength (420-nm) light. J Biol Rhythms. 2008 Oct;23(5):379-86. (PI: G.C. Brainard)
  10. Qiu D, Damron FH, Mima T, Schweizer HP, Yu HD. A series of PBAD-based shuttle vectors for functional analysis of toxic and highly-regulated genes in Pseudomonas and Burkholderia spp. and other bacteria. Appl Environ Microbiol. 2008 Oct 10. [Epub ahead of print] (PIs: F.H. Damron, NASA Graduate Student Researcher Program; H.D. Yu)

Other papers of interest:

  1. Sorond FA, Serrador JM, Jones RN, Shaffer ML, Lipsitz LA. The sit-to-stand technique for the measurement of dynamic cerebral autoregulation. Ultrasound Med Biol. 2008 Sep 30. [Epub ahead of print]
  2. Levine BD, Zhang R, Visocchi M, Ainslie PN, Ogoh S, Edvinsson L, Yildiz M, Paulson OB, Knudsen GM, Cassaglia PA, Griffiths RI, Walker AM, Immink RV, Passier RH, Prakash ES. Comments on Point:Counterpoint: Sympathetic activity does/does not influence cerebral blood flow. J Appl Physiol. 2008 Oct;105(4):1369-73. Note: These and others' comments are part of a discussion of this topic in this issue of the journal.
  3. Ishihara A, Fujino H, Nagatomo F, Takeda I, Ohira Y. Gene expression levels of heat shock proteins in the soleus and plantaris muscles of rats after hindlimb suspension or spaceflight. J Physiol Sci. 2008 Oct 11. [Epub ahead of print] Note: Shuttle results. This article may be obtained online without charge.
  4. Biolo G, Agostini F, Simunic B, Sturma M, Torelli L, Preiser JC, Deby-Dupont G, Magni P, Strollo F, di Prampero P, Guarnieri G, Mekjavic IB, Pisot R, Narici MV. Positive energy balance is associated with accelerated muscle atrophy and increased erythrocyte glutathione turnover during 5 wk of bed rest. Am J Clin Nutr. 2008 Oct;88(4):950-8.
  5. Ryall JG, Lynch GS. The potential and the pitfalls of beta-adrenoceptor agonists for the management of skeletal muscle wasting. Pharmacol Ther. 2008 Sep 16. [Epub ahead of print]
  6. Cosmi F, Steimberg N, Dreossi D, Mazzoleni G. Structural analysis of rat bone explants kept in vitro in simulated microgravity conditions. J Mech Behav Biomed Mater. 2008 Jul 6. [Epub ahead of print]
  7. McGee-Lawrence ME, Carey HV, Donahue SW. Mammalian hibernation as a model of disuse osteoporosis: The effects of physical inactivity on bone metabolism, structure, and strength. Am J Physiol Regul Integr Comp Physiol. 2008 Oct 8. [Epub ahead of print]
  8. Chen CS. Mechanotransduction - a field pulling together? J Cell Sci. 2008 Oct 15;121(Pt 20):3285-92. Note: This review attempts to pull together information about the various physical forces that affect tissues and cells, including a primer on mechanotransduction terminology and usage, and possible underlying mechanisms.
  9. Buravkova LB, Grigor'eva OV, Rykova MP, Grigor'ev AI. Cytotoxic activity of natural killer cells in vitro under microgravity. Dokl Biol Sci. 2008 Jul-Aug;421:275-7. Note: ISS results. This is an English translation of the Russian original published in Doklady Akademii Nauk 2008;421(1):128-30. The first page of the paper may be viewed without charge. Click to the issue and citation.
  10. Hamada N. Recent insights into the biological action of heavy-ion radiation. J Radiat Res (Tokyo). 2008 Oct 7. [Epub ahead of print] Note: This article may be obtained online without charge.
  11. Rithidech KN, Scott BR. Evidence for radiation hormesis after in vitro exposure of human lymphocytes to low doses of ionizing radiation. Dose Response. 2008;6(3):252-71. Epub 2008 May 21. Note: This article may be obtained online without charge via PubMed Central.
  12. Yakusheva T, Blazquez PM, Angelaki DE. Frequency-selective coding of translation and tilt in macaque cerebellar nodulus and uvula. J Neurosci. 2008 Oct 1;28(40):9997-10009.
  13. Viola AU, James LM, Archer SN, Dijk DJ. PER3 polymorphism and cardiac autonomic control: Effects of sleep debt and circadian phase. Am J Physiol Heart Circ Physiol. 2008 Oct 3. [Epub ahead of print]
  14. Gorgiladze GI. Regenerative capacity of the planarian Girardia tigrina and the snail Helix lucorum exposed to microgravity during an orbital flight on board the International Space Station. Dokl Biol Sci. 2008 Jul-Aug;421:244-7. Note: ISS results. This is an English translation of the Russian original published in Doklady Akademii Nauk 2008;421(1):131-4. The first page of the paper may be viewed without charge. Click to the issue and citation.

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