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NASA Spaceline 12 December 2008 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Friday, January 9, 2009

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Ortega MT, Pecaut MJ, Gridley DS, Stodieck LS, Ferguson VL, Chapes SK. Shifts in bone marrow cell phenotypes caused by space flight. J Appl Physiol. 2008 Dec 4. [Epub ahead of print] (PI: S.K. Chapes) Note: STS-118 results. The overall flight experiment was sponsored by Amgen.
  2. Zwart SR, Kala G, Smith SM. Body iron stores and oxidative damage in humans increased during and after a 10- to 12-day undersea dive. J Nutr. 2008 Dec 3. [Epub ahead of print] (PI: S.M. Smith) Note: NEEMO XII and XIII results.
  3. Iyengar MS, Carruth TN, Florez-Arango J, Dunn K. Informatics-based medical procedure assistance during space missions. Hippokratia. 2008 Aug;12 Suppl 1:23-7. Note: See citation #11 in the Other section for information about this issue. This article may be obtained online without charge via PubMed Central or at the publisher's site.
  4. Cardoso L, Herman BC, Verborgt O, Laudier D, Majeska RJ, Schaffler MB. Osteocyte apoptosis controls activation of intracortical resorption in response to bone fatigue. J Bone Miner Res. 2008 Dec 2. [Epub ahead of print] (PIs: L. Cardoso, NSBRI Postdoctoral Fellowship Program; M.B. Schaffler)
  5. Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell. 2008 Nov 28;135(5):907-18. (PI: P. Oberdoerffer) Note: This issue also contains a Preview article "Aging: A Sirtuin Shake-Up?" describing this research.
  6. Valtonen M, Nurmi P, Zheng JQ, Cucinotta FA, Wilson JW, Horneck G, Lindegren L, Melosh J, Rickman H, Mileikowsky C. Natural transfer of viable microbes in space from planets in extra-solar systems to a planet in our solar system and vice-versa. Astrophys J. 2009 Jan 1;690(1):210-5. (PIs: : J.W. Wilson, F.A. Cucinotta) Note: This article may be obtained online without charge.
  7. Conklin DJ, Lillywhite HB, Bishop B, Hargens AR, Olson KR. Rhythmic contractility in the hepatic portal "corkscrew" vein of the rat snake. Comp Biochem Physiol A Mol Integr Physiol. 2008 Nov 21. [Epub ahead of print] (PI: A.R. Hargens)

Other papers of interest:

  1. Folino AF, Russo G, Porta A, Buja G, Cerutti S, Iliceto S. Autonomic modulation and cardiac contractility in vasovagal syncope. Int J Cardiol. 2008 Dec 1. [Epub ahead of print]
  2. Arai TJ, Henderson AC, Dubowitz DJ, Levin DL, Friedman PJ, Buxton RB, Prisk GK, Hopkins SR. Hypoxic pulmonary vasoconstriction does not contribute to pulmonary blood flow heterogeneity in normoxia in normal supine humans. J Appl Physiol. 2008 Dec 4. [Epub ahead of print]
  3. Mack PJ, Zhang Y, Chung S, Vickerman V, Kamm RD, Garcia-Cardena G. Biomechanical regulation of endothelial-dependent events critical for adaptive remodeling. J Biol Chem. 2008 Dec 1. [Epub ahead of print] Note: This article may currently be obtained online without charge.
  4. Torcasio A, van Lenthe GH, Van Oosterwyck H. The importance of loading frequency, rate and vibration for enhancing bone adaptation and implant osseointegration. Eur Cell Mater. 2008 Nov 27;16:56-68. Note: This article includes a review and discussion of Clinton Rubin et al.'s research on vibration and bone. This article may be obtained online without charge.
  5. Li X, Ominsky MS, Warmington KS, Morony S, Gong J, Cao J, Gao Y, Shalhoub V, Tipton B, Haldankar R, Chen Q, Winters A, Boone T, Geng Z, Niu QT, Ke HZ, Kostenuik PJ, Simonet WS, Lacey DL, Paszty C. Sclerostin antibody treatment increases bone formation, bone mass and bone strength in a rat model of postmenopausal osteoporosis. J Bone Miner Res. 2008 Dec 2. [Epub ahead of print]
  6. Young SR, Gerard-O'Riley R, Kim JB, Pavalko FM. Focal adhesion kinase is important for fluid shear stress induced mechanotransduction in osteoblasts. J Bone Miner Res. 2008 Nov 18. [Epub ahead of print]
  7. Nagatomo F, Ishihara A, Ohira Y. Effects of hindlimb unloading at early postnatal growth on cell body size in spinal motoneurons innervating soleus muscle of rats. Int J Dev Neurosci. 2008 Nov 8. [Epub ahead of print]
  8. Matsuba Y, Goto K, Morioka S, Naito T, Akema T, Hashimoto N, Sugiura T, Ohira Y, Beppu M, Yoshioka T. Gravitational unloading inhibits the regenerative potential of atrophied soleus muscle in mice. Acta Physiol (Oxf). 2008 Nov 25. [Epub ahead of print]
  9. Rosi S, Andres-Mach M, Fishman KM, Levy W, Ferguson RA, Fike JR. Cranial irradiation alters the behaviorally induced immediate-early gene Arc (activity-regulated cytoskeleton-associated protein). Cancer Res. 2008 Dec 1;68(23):9763-70.
  10. Lai SK, Lai CH, Tse YC, Yung KK, Shum DK, Chan YS. Developmental maturation of ionotropic glutamate receptor subunits in rat vestibular nuclear neurons responsive to vertical linear acceleration. Eur J Neurosci. 2008 Dec;28(11):2157-72.
  11. Bamidis P, Kourtidou-Papadeli C. Guest editorial: Aspects of aerospace medicine. Hippokratia. 2008 Aug;12 Suppl 1:5. Note: This issue contains articles deriving from the 5th International Meeting of Aerospace Medicinie, held in Greece in 2007. Twelve of the 17 articles are listed here (one is in the NASA section). These articles may be obtained online without charge via PubMed Central or at the publisher's site.
  12. Vernikos J. Human exploration of space: Why, where, what for? Hippokratia. 2008 Aug;12 Suppl 1:6-9.
  13. Astaras A, Bamidis PD, Kourtidou-Papadeli C, Maglaveras N. Biomedical real-time monitoring in restricted and safety-critical environments. Hippokratia. 2008 Aug;12 Suppl 1:10-4.
  14. Kourtidou-Papadeli C, Papadelis CL, Vernikos J, Bamidis PD, Hitoglou-Antoniadou M, Perantoni E, Vlachogiannis E. The therapeutic benefits of gravity in space and on Earth. Hippokratia. 2008 Aug;12(Suppl 1):28-31.
  15. Russomano T, Falcao PF, Dalmarco G, Martinelli L, Cardoso R, Santos MA, Sparenberg A. The Brazilian research and teaching center in biomedicine and aerospace biomedical engineering. Hippokratia. 2008 Aug;12 Suppl 1:32-6.
  16. Jost PD. Simulating human space physiology with bed rest. Hippokratia. 2008 Aug;12 Suppl 1:37-40.
  17. Souvestre PA, Landrock CK, Blaber AP. Reducing incapacitating symptoms during space flight: Is Postural Deficiency Syndrome an applicable model? Hippokratia. 2008 Aug;12 Suppl 1:41-8.
  18. Horneck G. Astrobiological aspects of Mars and human presence: Pros and cons. Hippokratia. 2008 Aug;12 Suppl 1:49-52.
  19. Souvestre PA, Landrock CK, Blaber AP. New paradigm for understanding in-flight decision making errors: A neurophysiological model leveraging human factors. Hippokratia. 2008 Aug;12 Suppl 1:78-83.
  20. Kourtidou-Papadeli C, Papadelis C, Koutsonikolas D, Boutzioukas S, Styliadis C, Guiba-Tziampiri O. High altitude cognitive performance and COPD interaction. Hippokratia. 2008 Aug;12 Suppl 1:84-90.
  21. Koch B, Gerzer R. A research facility for habitation questions to be built at the German Aerospace Center in Cologne: Future challenges of space medicine. Hippokratia. 2008 Aug;12 Suppl 1:91-3.

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