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NASA Spaceline 2 January 2009 Current Space Life Science Awareness

Status Report From: Spaceline
Posted: Monday, February 9, 2009

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Keyak JH, Koyama AK, Leblanc A, Lu Y, Lang TF. Reduction in proximal femoral strength due to long-duration spaceflight. Bone. 2008 Dec 3. [Epub ahead of print] (PI: T.F. Lang) Note: ISS results. Substantial decreases in bone strength following long-duration space flight were observed, decreases that were notably greater than previously reported reductions in bone mineral density.
  2. Fu Q, Shibata S, Hastings JL, Prasad A, Palmer MD, Levine BD. Evidence for unloading arterial baroreceptors during low levels of lower body negative pressure in humans. Am J Physiol Heart Circ Physiol. 2008 Dec 12. [Epub ahead of print] (PI: B.D. Levine)
  3. Qin YX, Lam H. Intramedullary pressure and matrix strain induced by oscillatory skeletal muscle stimulation and its potential in adaptation. J Biomech. 2008 Dec 8. [Epub ahead of print] (PI: Y.X. Qin)
  4. Wilson JW, Ott CM, Quick L, Davis R, zu Bentrup KH, Crabbé A, Richter E, Sarker S, Barrila J, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Shah M, Nelman-Gonzalez M, Hing S, Parra M, Dumars P, Norwood K, Bober R, Devich J, Ruggles A, CdeBaca A, Narayan S, Benjamin J, Goulart C, Rupert M, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Porter MD, Pierson DL, Smith SM, Mergeay M, Leys N, Stefanyshyn-Piper HM, Gorie D, Nickerson CA. Media ion composition controls regulatory and virulence response of Salmonella in spaceflight. PLoS ONE. 2008;3(12):e3923. Epub 2008 Dec 12. (PI: C.A. Nickerson) Note: STS-115 and STS-123 results. This article may be obtained online without charge.
  5. Foster PP, Butler BD. Decompression to altitude: Assumptions, experimental evidence and future directions. J Appl Physiol. 2008 Dec 12. [Epub ahead of print] (PI: B.D. Butler) Note: A focus of this review is the relevance of decompression illness to microgravity and space flight.
  6. Kurpinski K, Jang DJ, Bhattacharya S, Rydberg B, Chu J, So J, Wyrobek A, Li S, Wang D. Differential effects of X-rays and high-energy (56)Fe ions on human mesenchymal stem cells. Int J Radiat Oncol Biol Phys. 2008 Dec 18. [Epub ahead of print] (PI: D. Wang)
  7. Finnberg N, Wambi C, Ware JH, Kennedy AR, El-Deiry WS. Gamma-radiation (GR) triggers a unique gene expression profile associated with cell death compared to proton radiation (PR) in mice in vivo. Cancer Biol Ther. 2008 Dec;7(12):2023-33. (PI: A.R. Kennedy)
  8. Yajima H, Lee KJ, Zhang S, Kobayashi J, Chen BP. DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases. J Mol Biol. 2008 Nov 27. [Epub ahead of print] (PI: B.P. Chen)
  9. Rogers NL, Dinges DF. Interaction of chronic sleep restriction and circadian system in humans. J Sleep Res. 2008 Dec;17(4):406-11. (PI: D.F. Dinges)
  10. Ingber DE. Tensegrity and mechanotransduction. J Bodyw Mov Ther. 2008 Jul;12(3):198-200. Epub 2008 Jun 16. (PI: D.E. Ingber)
  11. Moretti M, Freed LE, Padera RF, Laganà K, Boschetti F, Raimondi MT. An integrated experimental-computational approach for the study of engineered cartilage constructs subjected to combined regimens of hydrostatic pressure and interstitial perfusion. Biomed Mater Eng. 2008;18(4-5):273-8. (PI: L.E. Freed)

Other papers of interest:

  1. Bergouignan A, Trudel G, Simon C, Chopard A, Schoeller DA, Momken I, Votruba SB, Desage M, Burdge GC, Gauquelin-Koch G, Normand S, Blanc S. Physical inactivity differentially alters dietary oleate and palmitate trafficking. Diabetes. 2008 Nov 18. [Epub ahead of print] Note: WISE-2005 study.
  2. Calura E, Cagnin S, Raffaello A, Laveder P, Lanfranchi G, Romualdi C. Meta-analysis of expression signatures of muscle atrophy: Gene interaction networks in early and late stages. BMC Genomics. 2008 Dec 23;9:630. [Epub ahead of print] Note: This article may be obtained online without charge.
  3. Taaffe DR, Henwood TR, Nalls MA, Walker DG, Lang TF, Harris TB. Alterations in muscle attenuation following detraining and retraining in resistance-trained older adults. Gerontology. 2008 Dec 5. [Epub ahead of print]
  4. Dodd S, Hain B, Judge A. Hsp70 prevents disuse muscle atrophy in senescent rats. Biogerontology. 2008 Dec 13. [Epub ahead of print]
  5. Zhou P, Hu SM, Tong HY, Fu Q, Yang J, Gao XM, Zhang JJ. [Effect of Chinese herb medicine compound on bone loss in rats under 3 weeks simulated weightlessness: Preliminary study] Zhongguo Gu Shang. 2008 Sep;21(9):658-61. Chinese.
  6. Tong HY, Hu SM, Zhou P, Fu Q, Li J, Gao XM, Zhang JJ. [Effects on rats' bone mineral density and bone biomechanics by suspensory simulated weightlessness and removing suspension] Zhongguo Gu Shang. 2008 Apr;21(4):276-9. Chinese.
  7. Huselstein C, Netter P, de Isla N, Wang Y, Gillet P, Decot V, Muller S, Bensoussan D, Stoltz JF. Mechanobiology, chondrocyte and cartilage. Biomed Mater Eng. 2008;18(4-5):213-20.
  8. Sun XQ, Xu ZP, Zhang S, Cao XS, Liu TS. Simulated weightlessness aggravates hypergravity-induced impairment of learning and memory and neuronal apoptosis in rats. Behav Brain Res. 2008 Nov 30. [Epub ahead of print]
  9. Bizzarri M. [Consequences of space exploration for mankind] G Ital Nefrol. 2008 Nov-Dec;25(6):686-9. Italian.
  10. Ghandhi SA, Yaghoubian B, Amundson SA. Global gene expression analyses of bystander and alpha particle irradiated normal human lung fibroblasts: Synchronous and differential responses. BMC Med Genomics. 2008 Dec 24;1:63. [Epub ahead of print] Note: This article may be obtained online without charge.
  11. Mullington JM, Haack M, Toth M, Serrador JM, Meier-Ewert HK. Cardiovascular, inflammatory, and metabolic consequences of sleep deprivation. Prog Cardiovasc Dis. 2009 Jan-Feb;51(4):294-302. Note: The topic of this issue of the journal is sleep and cardiovascular disease. This article and the other articles may currently be obtained online without charge when accessed via the Table of Contents (click on the volume and issue in the publisher's site abstract).
  12. Dahlman J, Sjors A, Ledin T, Falkmer T. Could sound be used as a strategy for reducing symptoms of perceived motion sickness? J Neuroeng Rehabil. 2008 Dec 23;5:35. [Epub ahead of print] Note: Sound, as presented in this study, was not effective in reducing perceived motion sickness. This article may be obtained online without charge.
  13. Chung S, Sudo R, Mack PJ, Wan CR, Vickerman V, Kamm RD. Cell migration into scaffolds under co-culture conditions in a microfluidic platform. Lab Chip. 2009 Feb;9(2):269-75. Epub 2008 Oct 31.
  14. Platt TR, Burnside L, Bush E. The role of light and gravity in the experimental transmission of Echinostoma caproni (Digenea:Echinostomatidae) cercariae to the second intermediate host, Biomphalaria glabrata (Gastropoda:Pulmonata). J Parasitol. 2008 Oct 27:1. [Epub ahead of print]
  15. Chehab EW, Eich E, Braam J. Thigmomorphogenesis: A complex plant response to mechano-stimulation. J Exp Bot. 2008 Dec 18. [Epub ahead of print] Note: Review article by a former PI who conducted research on this topic.

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