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NASA Spaceline Current Awareness 17 July 2009

Status Report From: Spaceline
Posted: Sunday, September 6, 2009

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Phillips KP, Popovic ZB, Lim P, Meulet JE, Barrett CD, Di Biase L, Agler D, Thomas JD, Grimm RA. Opposing wall mechanics are significantly influenced by longitudinal cardiac rotation in the assessment of ventricular dyssynchrony. JACC Cardiovasc Imaging. 2009 Apr;2(4):379-86. (PI: J.D. Thomas)


  2. Chylack LT Jr, Peterson LE, Feiveson AH, Wear ML, Manuel FK, Tung WH, Hardy DS, Marak LJ, Cucinotta FA. NASA Study of Cataract in Astronauts (NASCA). Report 1: Cross-sectional study of the relationship of exposure to space radiation and risk of lens opacity. Radiat Res. 2009 Jul;172(1):10-20. (PI: L.T. Chylack)


  3. Bandstra ER, Thompson RW, Nelson GA, Willey JS, Judex S, Cairns MA, Benton ER, Vazquez ME, Carson JA, Bateman TA. Musculoskeletal changes in mice from 20-50 cGy of simulated galactic cosmic rays. Radiat Res. 2009 Jul;172(1):21-9. (PIs: G.A. Nelson, T.A. Bateman)


  4. Tian J, Pecaut MJ, Coutrakon GB, Slater JM, Gridley DS. Response of extracellular matrix regulators in mouse lung after exposure to photons, protons and simulated solar particle event protons. Radiat Res. 2009 Jul;172(1):30-41. (PI: D.S. Gridley)


  5. Henderson MA, Valluri S, DesRosiers C, Lopez JT, Batuello CN, Caperell-Grant A, Mendonca MS, Powers EM, Bigsby RM, Dynlacht JR. Effect of gender on radiation-induced cataractogenesis. Radiat Res. 2009 Jul;172(1):129-33. (PI: J.R. Dynlacht)


  6. Lin YF, Nagasawa H, Peng Y, Chuang EY, Bedford JS. Comparison of several radiation effects in human MCF10A mammary epithelial cells cultured as 2D monolayers or 3D acinar stuctures in matrigel. Radiat Res. 2009 Jun;171(6):708-15. (PI: J.S. Bedford)


  7. George KA, Hada M, Jackson LJ, Elliott T, Kawata T, Pluth JM, Cucinotta FA. Dose response of gamma rays and iron nuclei for induction of chromosomal aberrations in normal and repair-deficient cell lines. Radiat Res. 2009 Jun;171(6):752-63. (PIs: J.M. Pluth, F.A. Cucinotta)


  8. Elmore E, Lao XY, Kapadia R, Redpath JL. Threshold-type dose response for induction of neoplastic transformation by 1 GeV/nucleon iron ions. Radiat Res. 2009 Jun;171(6):764-70. (PI: J.L. Redpath)


  9. Yan B, Wang H, Xie D, Wakamatsu N, Anscher MS, Dewhirst MW, Mitchel RE, Chen BJ, Li CY. Increased skin carcinogenesis in caspase-activated DNase knockout mice. Carcinogenesis. 2009 Jun 18. [Epub ahead of print] (PI: C.Y. Li)


  10. Boyle RD, Rabbitt RD, Highstein SM. Efferent control of hair cell and afferent responses in the semicircular canals. J Neurophysiol. 2009 Jul 1. [Epub ahead of print] (PI: R.D. Boyle)


  11. Yoshikawa T, Sellix M, Pezuk P, Menaker M. Timing of the ovarian circadian clock is regulated by gonadotrophins. Endocrinology. 2009 Jun 11. [Epub ahead of print] (PI: M. Menaker)


  12. Wang Y, Xie Y, Wygle D, Shen HH, Puscheck EE, Rappolee DA. A major effect of simulated microgravity on several stages of preimplantation mouse development is lethality associated with elevated phosphorylated SAPK/JNK. Reprod Sci. 2009 Jun 22. [Epub ahead of print] (PI: D.A. Rappolee)


Other papers of interest:

  1. Christiansen BA, Kotiya AA, Silva MJ. Constrained tibial vibration does not produce an anabolic bone response in adult mice. Bone. 2009 Jun 30. [Epub ahead of print]


  2. Naderi J, Bernreuther C, Grabinski N, Putman CT, Henkel B, Bell G, Glatzel M, Sultan KR. Plasminogen activator inhibitor type 1 up-regulation is associated with skeletal muscle atrophy and associated fibrosis. Am J Pathol. 2009 Jul 2. [Epub ahead of print] Note: STS-58 (SLS-2, tissue-sharing program) results.


  3. Frey JW, Farley EE, O'Neil TK, Burkholder TJ, Hornberger TA. Evidence that mechanosensors with distinct biomechanical properties allow for specificity in mechanotransduction. Biophys J. 2009 Jul 8;97(1):347-56. Note: From abstract: "Based on these results, we propose that skeletal myoblasts contain multiple mechanosensory elements with distinct biomechanical properties and that these distinct biomechanical properties provide a mechanism for specificity in mechanotransduction."


  4. Choi H, Selpides P, Nowell M, Rourke BC. Functional overload in ground squirrel plantaris muscle fails to induce myosin isoform shifts. Am J Physiol Regul Integr Comp Physiol. 2009 Jun 24. [Epub ahead of print]


  5. Andersson T, Eliasson P, Aspenberg P. Tissue memory in healing tendons: Short loading episodes stimulate healing. J Appl Physiol. 2009 Jun 18. [Epub ahead of print]


  6. Eliasson P, Andersson T, Aspenberg P. Rat Achilles tendon healing: Mechanical loading and gene expression. J Appl Physiol. 2009 Jun 18. [Epub ahead of print]


  7. Tawhai MH, Nash MP, Lin CL, Hoffman EA. Supine and prone differences in regional lung density and pleural pressure gradients in the human lung with constant shape. J Appl Physiol. 2009 Jul 9. [Epub ahead of print]


  8. Chen HL, Qu LN, Li QD, Bi L, Huang ZM, Li YH. [Simulated microgravity-induced oxidative stress in different areas of rat brain] Sheng Li Xue Bao. 2009 Apr 25;61(2):108-14. Chinese.


  9. Sajdel-Sulkowska EM, Xu M, Koibuchi N. Cerebellar brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 expression in male and female rats is differentially affected by hypergravity exposure during discrete developmental periods. Cerebellum. 2009 Jul 3. [Epub ahead of print]


  10. Ainsbury EA, Bouffler SD, Dörr W, Graw J, Muirhead CR, Edwards AA, Cooper J. Radiation cataractogenesis: A review of recent studies. Radiat Res. 2009 Jul;172(1):1-9.


  11. Hall EJ, Metting N, Puskin J, Ron E. Low dose radiation epidemiology: What can it tell us? Radiat Res. 2009 Jul;172(1):134-8. Note: This is a meeting report.


  12. Chouin N, Bernardeau K, Davodeau F, Chérel M, Faivre-Chauvet A, Bourgeois M, Apostolidis C, Morgenstern A, Lisbona A, Bardiès M. Evidence of extranuclear cell sensitivity to alpha-particle radiation using a microdosimetric model. I. Presentation and validation of a microdosimetric model. Radiat Res. 2009 Jun;171(6):657-63.


  13. Chouin N, Bernardeau K, Bardiès M, Faivre-Chauvet A, Bourgeois M, Apostolidis C, Morgenstern A, Lisbona A, Chérel M, Davodeau F. Evidence of extranuclear cell sensitivity to alpha-particle radiation using a microdosimetric model. II. Application of the microdosimetric model to experimental results. Radiat Res. 2009 Jun;171(6):664-73.


  14. Yoon AJ, Shen J, Wu HC, Angelopoulos C, Singer SR, Chen R, Santella RM. Expression of activated checkpoint kinase 2 and histone 2AX in exfoliative oral cells after exposure to ionizing radiation. Radiat Res. 2009 Jun;171(6):771-5.


  15. Fournier C, Barberet P, Pouthier T, Ritter S, Fischer B, Voss KO, Funayama T, Hamada N, Kobayashi Y, Taucher-Scholz G. No evidence for DNA and early cytogenetic damage in bystander cells after heavy-ion microirradiation at two facilities. Radiat Res. 2009 May;171(5):530-40.


  16. Ivey RG, Subramanian O, Lorentzen TD, Paulovich AG. Antibody-based screen for ionizing radiation-dependent changes in the mammalian proteome for use in biodosimetry. Radiat Res. 2009 May;171(5):549-61.


  17. Singh S, Cowen RL, Chinje EC, Stratford IJ. The impact of intracellular generation of nitric oxide on the radiation response of human tumor cells. Radiat Res. 2009 May;171(5):572-80.


  18. Luu QT, DuChateau P. The relative biologic effectiveness versus linear energy transfer curve as an output-input relation for linear cellular systems. Math Biosci Eng. 2009 Jul;6(3):591-602. Note: This article may be obtained online without charge.


  19. Xue L, Yu D, Furusawa Y, Cao J, Okayasu R, Fan S. Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation. Mutat Res. 2009 Jul 4. [Epub ahead of print]


  20. Tarnutzer AA, Bockisch CJ, Straumann D, Olasagasti I. Gravity-dependence of subjective visual vertical variability. J Neurophysiol. 2009 Jul 1. [Epub ahead of print]


  21. Mastroleo F, Van Houdt R, Leroy B, Benotmane MA, Janssen A, Mergeay M, Vanhavere F, Hendrickx L, Wattiez R, Leys N. Experimental design and environmental parameters affect Rhodospirillum rubrum S1H response to space flight. ISME J. 2009 Jul 2. [Epub ahead of print] Note: ISS results.


  22. Leys N, Baatout S, Rosier C, Dams A, s'Heeren C, Wattiez R, Mergeay M. The response of Cupriavidus metallidurans CH34 to spaceflight in the International Space Station. Antonie Van Leeuwenhoek. 2009 Jul 2. [Epub ahead of print] Note: ISS results.


  23. Cárdenas L. New findings in the mechanisms regulating polar growth in root hair cells. Plant Signal Behav. 2009 Jan;4(1):4-8. Note: This article may be obtained online without charge via PubMed Central.


  24. Desikan P. Microbes, the moon, and H1N1. Indian J Med Microbiol. 2009 Jul-Sep;27(3):182-4. Note: The author draws parallels between evolutionary aspects of space exploration and the evolution of viruses, specifically the H1N1 virus. This article may be obtained online without charge.






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