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NASA Spaceline Current Awareness 2 October 2009

Status Report From: Spaceline
Posted: Monday, October 26, 2009

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

  1. Whitson PA, Pietrzyk RA, Jones JA, Nelman-Gonzalez M, Hudson EK, Sams CF. Effect of potassium citrate therapy on the risk of renal stone formation during spaceflight. J Urol. 2009 Sep 17. [Epub ahead of print] (PI: P.A. Whitson) Note: Mir and ISS results.
  2. Sa RC, Prisk GK, Paiva M. Microgravity alters respiratory abdominal and rib cage motion during sleep. J Appl Physiol. 2009 Sep 24. [Epub ahead of print] (PI: J.B. West/G.K. Prisk) Note: STS-90 (Neurolab) and STS-95 results.
  3. Serrador JM, Schlegel TT, Black FO, Wood SJ. Vestibular effects on cerebral blood flow. BMC Neurosci. 2009 Sep 23;10:119. [Epub ahead of print] (PI: J.M. Serrador) Note: This article may be obtained online without charge.
  4. Baecker N, Frings-Meuthen P, Smith SM, Heer M. Short-term high dietary calcium intake during bedrest has no effect on markers of bone turnover in healthy men. Nutrition. 2009 Sep 17. [Epub ahead of print]
  5. Clark BC. In vivo alterations in skeletal muscle form and function after disuse atrophy. Med Sci Sports Exerc. 2009 Oct;41(10):1869-75. (PI: B.C. Clark, NASA Graduate Student Researcher Program)
  6. Ren G, Su J, Zhang L, Zhao X, Ling W, L'huillie A, Zhang J, Lu Y, Roberts AI, Ji W, Zhang H, Rabson AB, Shi Y. Species variation in the mechanisms of mesenchymal stem cell-mediated immunosuppression. Stem Cells. 2009 Aug;27(8):1954-62. (PI: Y. Shi)
  7. Sanzari JK, Nuth M, Kennedy AR. Induction of cytokine gene expression in human thyroid epithelial cells irradiated with HZE particles (iron ions). Radiat Res. 2009 Oct;172(4):437-43. (PI: A.R. Kennedy)
  8. Kuhne WW, Gersey BB, Wilkins R, Wu H, Wender SA, George V, Dynan WS. Biological effects of high-energy neutrons measured in vivo using a vertebrate model. Radiat Res. 2009 Oct;172(4):473-80. Note: This article may be obtained online without charge.
  9. Xie H, Holmes AL, Young JL, Qin Q, Joyce K, Pelsue SC, Peng C, Wise SS, Jeevarajan AS, Wallace WT, Hammond D, Wise JP Sr. Zinc chromate induces chromosome instability and DNA double strand breaks in human lung cells. Toxicol Appl Pharmacol. 2009 Feb 1;234(3):293-9. Epub 2008 Nov 5.
  10. Czeisler CA. Medical and genetic differences in the adverse impact of sleep loss on performance: Ethical considerations for the medical profession. Trans Am Clin Climatol Assoc. 2009;120:249-85. (PI: C.A. Czeisler) Note: This article may be obtained online without charge via PubMed Central.

Other papers of interest:

  1. Yogev D, Eiken O, Pisot R, Biolo G, di Prampero P, Narici M, Mekjavic IB. Effect of 21 days of horizontal bed rest on behavioural thermoregulation. Eur J Appl Physiol. 2009 Sep 25. [Epub ahead of print]
  2. Burrowes KS, Hoffman EA, Tawhai MH. Species-specific pulmonary arterial asymmetry determines species differences in regional pulmonary perfusion. Ann Biomed Eng. 2009 Sep 19. [Epub ahead of print]
  3. Deogenov VA, Zorbas YG, Kakuris KK, Federenko YF. The impact of physical exercise on calcium balance in healthy subjects during prolonged hypokinesia. Nutrition. 2009 Oct;25(10):1029-34.
  4. Lang T, Streeper T, Cawthon P, Baldwin K, Taaffe DR, Harris TB. Sarcopenia: Etiology, clinical consequences, intervention, and assessment. Osteoporos Int. 2009 Sep 25. [Epub ahead of print] Note: This article may be obtained online without charge.
  5. Urso ML. Regulation of muscle atrophy: Wasting away from the outside in: An introduction. Med Sci Sports Exerc. 2009 Oct;41(10):1856-9. Note: This paper and the next two papers and paper #5 in the NASA section derive from a symposium on muscle atrophy. Table of Contents of this issue.
  6. Urso ML. Disuse atrophy of human skeletal muscle: Cell signaling and potential interventions. Med Sci Sports Exerc. 2009 Oct;41(10):1860-8.
  7. Siu PM. Muscle apoptotic response to denervation, disuse, and aging. Med Sci Sports Exerc. 2009 Oct;41(10):1876-86.
  8. Prakash D, Behari J. Synergistic role of hydroxyapatite nanoparticles and pulsed electromagnetic field therapy to prevent bone loss in rats following exposure to simulated microgravity. Int J Nanomedicine. 2009;4:133-44. Epub 2009 Sep 10. Note: This article may be obtained online without charge.
  9. Huang Y, Dai ZQ, Ling SK, Zhang HY, Wan YM, Li YH. Gravity, a regulation factor in the differentiation of rat bone marrow mesenchymal stem cells. J Biomed Sci. 2009 Sep 21;16:87. Note: This article may be obtained online without charge.
  10. Courtine G, Gerasimenko Y, van den Brand R, Yew A, Musienko P, Zhong H, Song B, Ao Y, Ichiyama RM, Lavrov I, Roy RR, Sofroniew MV, Edgerton VR. Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nat Neurosci. 2009 Oct;12(10):1333-42. Epub 2009 Sep 20. Note: This article reports significant progress in this research area.
  11. Martin L, Marples B, Coffey M, Lawler M, Hollywood D, Marignol L. Recognition of O6MeG lesions by MGMT and mismatch repair proficiency may be a prerequisite for low-dose radiation hypersensitivity. Radiat Res. 2009 Oct;172(4):405-13.
  12. Jiang J, McDonald PR, Dixon TM, Franicola D, Zhang X, Nie S, Epperly LD, Huang Z, Kagan VE, Lazo JS, Epperly MW, Greenberger JS. Synthetic protection short interfering RNA screen reveals glyburide as a novel radioprotector. Radiat Res. 2009 Oct;172(4):414-22.
  13. Dieriks B, De Vos W, Meesen G, Van Oostveldt K, De Meyer T, Ghardi M, Baatout S, Van Oostveldt P. High content analysis of human fibroblast cell cultures after exposure to space radiation. Radiat Res. 2009 Oct;172(4):423-36. Note: Foton-M3 results.
  14. MacLaren A, Slavin D, McGowan CH. Chk2 protects against radiation-induced genomic instability. Radiat Res. 2009 Oct;172(4):463-72.
  15. Apostolov EO, Soultanova I, Savenka A, Bagandov OO, Yin X, Stewart AG, Walker RB, Basnakian AG. Deoxyribonuclease I is essential for DNA fragmentation induced by gamma radiation in mice. Radiat Res. 2009 Oct;172(4):481-92.
  16. Lejeune L, Thouvarecq R, Anderson DJ, Caston J, Jouen F. Kinaesthetic and visual perceptions of orientations. Perception. 2009;38(7):988-1001.
  17. Chowdhury SA, Takahashi K, DeAngelis GC, Angelaki DE. Does the middle temporal area carry vestibular signals related to self-motion? J Neurosci. 2009 Sep 23;29(38):12020-30.
  18. Mammoto A, Ingber DE. Cytoskeletal control of growth and cell fate switching. Curr Opin Cell Biol. 2009 Sep 8. [Epub ahead of print]
  19. Rieffel JA, Valero-Cuevas FJ, Lipson H. Morphological communication: Exploiting coupled dynamics in a complex mechanical structure to achieve locomotion. J R Soc Interface. 2009 Sep 23. [Epub ahead of print] Note: This article may be obtained online without charge.
  20. Exley C. Darwin, natural selection and the biological essentiality of aluminium and silicon. Trends Biochem Sci. 2009 Sep 20. [Epub ahead of print] Note: As discussed in the abstract, the question was raised: which was more important to life on Earth, gravity or natural selection? The author chose natural selection.


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