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NASA Spaceline Current Awareness January 15, 2010

Status Report From: Spaceline
Posted: Friday, January 15, 2010

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

Puwanant S, Park M, Popovic ZB, Tang WH, Farha S, George D, Sharp J, Puntawangkoon J, Loyd JE, Erzurum SC, Thomas JD. Ventricular geometry, strain, and rotational mechanics in pulmonary hypertension. Circulation. 2010 Jan 4. [Epub ahead of print] (PI: J.D. Thomas)

Zafar F, Seidler SB, Kronenberg A, Schild D, Wiese C. Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions. Radiat Res. 2010 Jan;173(1):27-39. (PI: C. Wiese)

Lee TY, Muschal S, Pravda EA, Folkman J, Abdollahi A, Javaherian K. Angiostatin regulates the expression of antiangiogenic and proapoptotic pathways via targeted inhibition of mitochondrial proteins. Blood. 2009 Aug 27;114(9):1987-98. Epub 2009 May 22. (PI: L. Hlatky/J. Folkman/A. Abdollahi/NSCOR) Note: A comment on this paper that describes the research can be obtained online without charge.


Li M, Abdollahi A, Groene HJ, Lipson KE, Belka C, Huber PE. Late treatment with imatinib mesylate ameliorates radiation-induced lung fibrosis in a mouse model. Radiat Oncol. 2009 Dec 21;4:66. (PI: L. Hlatky/P.E. Huber/NSCOR) Note: This article may be obtained online without charge.


George NI, Lupton JR, Turner ND, Chapkin RS, Davidson LA, Wang N. Evaluation of fecal mRNA reproducibility via a marginal transformed mixture modeling approach. BMC Bioinformatics. 2010 Jan 7;11:13. [Epub ahead of print] (PI: J.R. Lupton) Note: This article may be obtained online without charge.


Cohen DA, Wang W, Wyatt JK, Kronauer RE, Dijk DJ, Czeisler CA, Klerman EB. Uncovering residual effects of chronic sleep loss on human performance. Sci Transl Med. 2010 Jan 13;2(14):14ra3. (PI: E.B. Klerman) Note: This paper is described in numerous media articles and is featured on the cover of the journal.


Khodakovskaya M, Sword C, Wu Q, Perera IY, Boss WF, Brown CS, Winter Sederoff H. Increasing inositol (1,4,5)-trisphosphate metabolism affects drought tolerance, carbohydrate metabolism and phosphate-sensitive biomass increases in tomato. Plant Biotechnol J. 2010 Feb;8(2):170-83. Epub 2009 Dec 21. (PIs: C.S. Brown, H. Winter Sederoff)


Other papers of interest:

Truijen J, Bundgaard-Nielsen M, van Lieshout JJ. A definition of normovolaemia and consequences for cardiovascular control during orthostatic and environmental stress. Eur J Appl Physiol. 2010 Jan 7. [Epub ahead of print] Note: This article has a section on microgravity and bed rest. It may be obtained online without charge.


Sheriff DD, Nadland IH, Toska K. Role of sympathetic responses on the hemodynamic consequences of rapid changes in posture in humans. J Appl Physiol. 2010 Jan 7. [Epub ahead of print]

Sheriff DD, Nadland IH, Toska K. Retrograde arterial leg blood flow during tilt-back from a head-up posture: Importance of capacitive flows when arterial pressure changes. J Appl Physiol. 2010 Jan 7. [Epub ahead of print]

Lew PS, Wong D, Yamaguchi T, Leckstrom A, Schwartz J, Dodd JG, Mizuno TM. Tail suspension increases energy expenditure independently of the melanocortin system in mice. Can J Physiol Pharmacol. 2009 Oct;87(10):839-49.

Ozcivici E, Luu YK, Adler B, Qin YX, Rubin J, Judex S, Rubin CT. Mechanical signals as anabolic agents in bone. Nat Rev Rheumatol. 2010 Jan;6(1):50-9.

Shivaram GM, Kim CH, Batra NN, Yang W, Harris SE, Jacobs CR. Novel early response genes in osteoblasts exposed to dynamic fluid flow. Philos Transact A Math Phys Eng Sci. 2010 Feb 13;368(1912):605-16. Note: This article may be obtained online without charge.


Manolagas SC. From estrogen-centric to aging and oxidative stress: A revised perspective of the pathogenesis of osteoporosis. Endocr Rev. 2010 Jan 5. [Epub ahead of print]

Weinstein RS, Wan C, Liu Q, Wang Y, Almeida M, O'Brien CA, Thostenson J, Roberson PK, Boskey AL, Clemens TL, Manolagas SC. Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in 21-month-old mice. Aging Cell. 2009 Dec 28. [Epub ahead of print]

Yoshimitsu K, Shiba N, Matsuse H, Takano Y, Matsugaki T, Inada T, Tagawa Y, Nagata K. Development of a training method for weightless environment using both electrical stimulation and voluntary muscle contraction. Tohoku J Exp Med. 2010 Jan;220(1):83-93. Note: Parabolic flight results. This article may be obtained online without charge.


Kawano F, Goto K, Wang XD, Terada M, Ohira T, Nakai N, Yoshioka T, Ohira Y. Role(s) of gravitational loading during developing period on the growth of rat soleus muscle fibers. J Appl Physiol. 2010 Jan 7. [Epub ahead of print]

Kim J, Won KJ, Lee HM, Hwang BY, Bae YM, Choi WS, Song H, Lim KW, Lee CK, Kim B. p38 MAPK participates in muscle-specific RING finger 1-mediated atrophy in cast-immobilized rat gastrocnemius muscle. Korean J Physiol Pharmacol. 2009 Dec;13(6):491-6. Epub 2009 Dec 31. Note: This article may be obtained online without charge.


Ciciliot S, Schiaffino S. Regeneration of mammalian skeletal muscle. Basic mechanisms and clinical implications. Curr Pharm Des. 2009 Dec 24. [Epub ahead of print]

Anderson DE, Nussbaum MA, Madigan ML. A new method for gravity correction of dynamometer data and determining passive elastic moments at the joint. J Biomech. 2010 Jan 4. [Epub ahead of print]

Angelaki DE, Yakusheva TA, Green AM, Dickman JD, Blazquez PM. Computation of egomotion in the macaque cerebellar vermis. Cerebellum. 2009 Dec 11. [Epub ahead of print]

Shefer S, Gordon C, Avraham KB, Mintz M. Progressive vestibular mutation leads to elevated anxiety. Brain Res. 2010 Jan 4. [Epub ahead of print]

Pietsch J, Kussian R, Sickmann A, Bauer J, Weber G, Nissum M, Westphal K, Egli M, Grosse J, Schoenberger J, Wildgruber R, Infanger M, Grimm D. Application of free-flow isoelectric focusing to identify protein candidates changing under microgravity conditions. Proteomics. 2010 Jan 4. [Epub ahead of print]

Gao W, Li K, Yan S, Gao X, Hu L. Effects of space flight on DNA mutation and secondary metabolites of licorice (Glycyrrhiza uralensis Fisch.). Sci China C Life Sci. 2009 Oct;52(10):977-81. Epub 2009 Nov 13. Note: Results from plants grown from seeds flown on a Chinese satellite.


Taniguchi YY, Taniguchi M, Tsuge T, Oka A, Aoyama T. Involvement of Arabidopsis thaliana phospholipase Dzeta2 in root hydrotropism through the suppression of root gravitropism. Planta. 2009 Jan;231(2):491-7. Epub 2009 Nov 14.

Qin W, Gao YF, Xue W, Zhang HX, Wang HP, Hinghofer-Szalkay H. Effects of two Chinese herbs on muscle composition after 14 d of hind-limb unloading in rats. Space Med Med Eng (Beijing). 2009 Aug;22(4):235-9. Note: Bibliographic information, and usually an abstract, for the individual papers in this journal is available at the links given with the individual citations. Journal main site.


Liu YS, Jin Z, Wu B, Zhao DM, Sun HY, Pan ZC, Li K, Wu P, Gu ZM, Zeng YW, Liu G, Geng J, Sun XQ. [Effects of exercise training during 30 d -6* head-down bed rest on lower limb muscle atrophy and function changes] Space Med Med Eng (Beijing). 2009 Aug;22(4):240-6. Chinese.

Meng R, Xu HY, Wang Z, Zhang W, Shang P. [Effects of conditioned medium of osteocytes subjected to simulated weightlessness on activity of osteoblasts] Space Med Med Eng (Beijing). 2009 Aug;22(4):247-51. Chinese.

Zhang WH, Qi P, Yang F, Wang HH, Ling SK, Wang R, Li YH. [Myocardial apoptosis induced by simulated weightlessness in rats] Space Med Med Eng (Beijing). 2009 Aug;22(4):252-4. Chinese.

Mao T, Song BY, Wang ZW. [Analysis for the performance of zeolite 5A molecular sieve to adsorb CO2 in crew module] Space Med Med Eng (Beijing). 2009 Aug;22(4):255-8. Chinese.

Wei L, Sun HR, Yu C, Lai Y, Zeng Y, Liu XH. [Effects of laminar shear stress on the protein expression of IL-8 receptor CXCR2 in endothelial cells] Space Med Med Eng (Beijing). 2009 Aug;22(4):259-62. Chinese.

Jia B, Shang P. [Research progress of biological effects of hypomagnetic fields] Space Med Med Eng (Beijing). 2009 Aug;22(4):308-12. Chinese.

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