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NASA Spaceline Current Awareness April 9, 2010

Status Report From: Spaceline
Posted: Friday, April 9, 2010

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

Priest ND, Hoel DG, Brooks PN. Relative toxicity of (45)Ca beta-particles and (242)Cm alpha-particles following their intravenous injection into mice as radiolabelled FAP. Int J Radiat Biol. 2010 Apr;86(4):300-20. (PI: D.G. Hoel) Note: A figure from this article is shown on the cover of the journal.

Kim MH, Qualls GD, Slaba TC, Cucinotta FA. Comparison of organ dose and dose equivalent for human phantoms of CAM vs. MAX. Adv Space Res. 2010 Apr 1;45(7):850-7. (PI: F.A. Cucinotta) Note: Limited ISS results are presented in this article. This article and 11 other articles in this list comprise a "Life Sciences in Space" issue. One other article from the issue is not included in this list. The Table of Contents can be viewed by clicking on the volume and issue at the upper left of the publisher's abstract.

Slaba TC, Qualls GD, Clowdsley MS, Blattnig SR, Walker SA, Simonsen LC. Utilization of CAM, CAF, MAX, and FAX for space radiation analyses using HZETRN. Adv Space Res. 2010 Apr 1;45(7):866-83.

Mertens CJ, Moyers MF, Walker SA, Tweed J. Proton lateral broadening distribution comparisons between GRNTRN, MCNPX, and laboratory beam measurements. Adv Space Res. 2010 Apr 1;45(7):884-91.

Benice TS, Raber J. Castration and training in a spatial task alter the number of immature neurons in the hippocampus of male mice. Brain Res. 2010 Mar 15. [Epub ahead of print] (PI: J. Raber)

Sellix MT, Yoshikawa T, Menaker M. A circadian egg timer gates ovulation. Curr Biol. 2010 Mar 23;20(6):R266-7. (PI: M. Menaker) Note: This article may be obtained online without charge.

Jones HW, Kliss MH. Exploration life support technology challenges for the Crew Exploration Vehicle and future human missions. Adv Space Res. 2010 Apr 1;45(7):917-28.

Other papers of interest:

Kirkpatrick AW, Keaney MA, Bentz K, Groleau M, Tyssen M, Keyte J, Ball CG, Campbell MR, Grenon SM, McBeth P, Broderick TJ. The use of the National Research Council of Canada's Falcon 20 research aircraft as a terrestrial analogue space environment (TASE) for space surgery research: Challenges and suggested solutions. Planet Space Sci. 2010 Mar;58(4):717-23. Note: Parabolic flight results. This article and the following article and two articles appearing later in this list are from an issue titled: "Exploring other worlds by exploring our own: The role of terrestrial analogue studies in planetary exploration." The issue focused primarily on geology and astrobiology. The Table of Contents can be viewed by clicking on the volume and issue at the upper left of the publisher's abstract.

Ball CG, Keaney MA, Chun R, Groleau M, Tyssen M, Keyte J, Broderick TJ, Kirkpatrick AW. Anesthesia and critical-care delivery in weightlessness: A challenge for research in parabolic flight analogue space surgery studies. Planet Space Sci. 2010 Mar;58(4):732-40. Note: Parabolic flight results. From conclusion of the abstract: "With careful organization of caregivers, equipment and protocols, providing anesthesia and life support in weightlessness is theoretically possible. Unfortunately, human resource costs are extensive and likely overwhelming."

Bringard A, Pogliaghi S, Adami A, De Roia G, Lador F, Lucini D, Pizzinelli P, Capelli C, Ferretti G. Cardiovascular determinants of maximal oxygen consumption in upright and supine posture at the end of prolonged bed rest in humans. Respir Physiol Neurobiol. 2010 Mar 27. [Epub ahead of print] Note: This bed rest study was organized by the Italian Space Agency and a university in Slovenia and it took place in Slovenia.

Kamiya A, Kawada T, Mizuno M, Shimizu S, Sugimachi M. Parallel resetting of arterial baroreflex control of renal and cardiac sympathetic nerve activities during upright tilt in rabbits. Am J Physiol Heart Circ Physiol. 2010 Mar 26. [Epub ahead of print]

Mueller PJ. Physical (in)activity dependent alterations at the rostral ventrolateral medulla: Influence on sympathetic nervous system regulation. Am J Physiol Regul Integr Comp Physiol. 2010 Mar 31. [Epub ahead of print]

Stenekes MW, Coert JH, Nicolai JP, Mulder T, Geertzen JH, Paans AM, de Jong BM. Cerebral consequences of dynamic immobilisation after primary digital flexor tendon repair. J Plast Reconstr Aesthet Surg. 2010 Mar 19. [Epub ahead of print]

Kalogeropoulos M, Varanasi SS, Olstad OK, Sanderson P, Gautvik VT, Reppe S, Francis RM, Gautvik KM, Birch MA, Datta HK. Zic1 transcription factor in bone: Neural developmental protein regulates mechanotransduction in osteocytes. FASEB J. 2010 Apr 6. [Epub ahead of print]

Hu SM, Zhou P, Fu Q, Yang JJ, Gao XM. [Effect of a Chinese herbal prescription on collagen I in rat's femur under simulated weightlessness] Zhongguo Gu Shang. 2010 Feb;23(2):117-9. Chinese.

Redline S, Lewis EF. Gravitational influences and shifting propensity for sleep apnea. Another source of heterogeneity or a new intervention target? Circulation. 2010 Mar 29. [Epub ahead of print] Note: This article comments on a research article by Yumino et al.: "Nocturnal rostral fluid shift. A unifying concept for the pathogenesis of obstructive and central sleep apnea in men with heart failure." It is suggested that headward fluid shifts occurring during sleep are a cause of sleep apnea in men with heart failure. Space/bed rest studies on fluid shifts and sleep (e.g., PubMed 11500354) are not mentioned in the two articles.

Lazzer S, Plaino L, Antonutto G. The energetics of cycling on Earth, Moon and Mars. Eur J Appl Physiol. 2010 Mar 27. [Epub ahead of print]

Booth FW, Laye MJ. The future: Genes, physical activity, and health. Acta Physiol (Oxf). 2010 Mar 24. [Epub ahead of print]

Chen Y, Li Y, Zhang H, Xie Y, Chen X, Ren J, Zhang X, Zhu Z, Liu H, Zhang Y. Early effects of low dose 12C6+ ion or X-ray irradiation on human peripheral blood lymphocytes. Adv Space Res. 2010 Apr 1;45(7):832-8.

Wang G, Hao Z, Anken RH, Lu J, Liu Y. Effects of UV-B radiation on photosynthesis activity of Wolffia arrhiza as probed by chlorophyll fluorescence transients. Adv Space Res. 2010 Apr 1;45(7):839-45.

Khan E, Marechal F, Dendale R, Mabit C, Calugaru V, Desjardin L, Narici L. Anomalous phosphenes in ocular proton therapy. Adv Space Res. 2010 Apr 1;45(7):846-9.

Semkova J, Koleva R, Maltchev S, Kanchev N, Benghin V, Chernykh I, Shurshakov V, Petrov V, Yarmanova E, Bankov N, Lyagushin V, Goranova M. Radiation measurements inside a human phantom aboard the International Space Station using Liulin-5 charged particle telescope. Adv Space Res. 2010 Apr 1;45(7):858-65. Note: ISS results.

Sihver L, Sato T, Gustafsson K, Mancusi D, Iwase H, Niita K, Nakashima H, Sakamoto Y, Iwamoto Y, Matsuda N. An update about recent developments of the PHITS code. Adv Space Res. 2010 Apr 1;45(7):892-9.

Spillantini P. Active shielding for long duration interplanetary manned missions. Adv Space Res. 2010 Apr 1;45(7):900-16.

Kadhim MA, Lee R, Moore SR, Macdonald DA, Chapman KL, Patel G, Prise KM. Genomic instability after targeted irradiation of human lymphocytes: Evidence for inter-individual differences under bystander conditions. Mutat Res. 2010 Mar 27. [Epub ahead of print]

Partridge MA, Chai Y, Zhou H, Hei TK. High-throughput antibody-based assays to identify and quantify radiation-responsive protein biomarkers. Int J Radiat Biol. 2010 Apr;86(4):321-8.

Percie du Sert N, Chu KM, Wai MK, Rudd JA, Andrews PL. Telemetry in a motion-sickness model implicates the abdominal vagus in motion-induced gastric dysrhythmia. Exp Physiol. 2010 Apr 1. [Epub ahead of print]

Schneider S, Bruemmer V, Carnahan H, Kleinert J, Piacentini MF, Meeusen R, Strueder HK. Exercise as a countermeasure to psycho-physiological deconditioning during long-term confinement. Behav Brain Res. 2010 Mar 25. [Epub ahead of print] Note: Results are presented for a 105-day isolation study, a precursor to the MARS500 isolation study.

Suedfeld P. Historical space psychology: Early terrestrial explorations as Mars analogues. Planet Space Sci. 2010 Mar;58(4):639-45.

Forrest AL, Laval BE, Lim DS, Williams DR, Trembanis AC, Marinova MM, Shepard R, Brady AL, Slater GF, Gernhardt ML, McKay CP. Performance evaluation of underwater platforms in the context of space exploration. Planet Space Sci. 2010 Mar;58(4):706-16.

Liu L, Yuan W, Wang J. Mechanisms for osteogenic differentiation of human mesenchymal stem cells induced by fluid shear stress. Biomech Model Mechanobiol. 2010 Mar 23. [Epub ahead of print]

Gomez EW, Chen QK, Gjorevski N, Nelson CM. Tissue geometry patterns epithelial-mesenchymal transition via intercellular mechanotransduction. J Cell Biochem. 2010 Mar 24. [Epub ahead of print]

Ochsner M, Textor M, Vogel V, Smith ML. Dimensionality controls cytoskeleton assembly and metabolism of fibroblast cells in response to rigidity and shape. PLoS One. 2010 Mar 23;5(3):e9445. Note: This article may be obtained online without charge.

Gohil HL, Bucklin RA, Correll MJ. The effects of CO2 on growth and transpiration of radish (Raphanus sativus) in hypobaria. Adv Space Res. 2010 Apr 1;45(7):823-31.

Hu E, Bartsev SI, Liu H. Conceptual design of a bioregenerative life support system containing crops and silkworms. Adv Space Res. 2010 Apr 1;45(7):929-39.



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