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NASA Spaceline Current Awareness May 21, 2010

Status Report From: Spaceline
Posted: Friday, May 21, 2010

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

Summers RL, Martin DS, Platts SH, Mercado-Young R, Coleman TG, Kassemi M. Ventricular chamber sphericity during spaceflight and parabolic flight intervals of less than 1 G. Aviat Space Environ Med. 2010 May;81(5):506-10. (PIs: S. Wood, S.H. Platts) Note: STS and parabolic flight results.

Cavanagh PR, Genc KO, Gopalakrishnan R, Kuklis MM, Maender CC, Rice AJ. Foot forces during typical days on the International Space Station. J Biomech. 2010 May 11. [Epub ahead of print] (PI: P.R. Cavanagh) Note: ISS results. From Discussion of paper: "Only ~30% of the time assigned for exercise on the ISS resulted in measureable loading. The remainder of the time period was presumably spent in setup, device adjustment, rest, attending to non-exercise related tasks, or tear down. While flight surgeons and the Astronaut Strength Conditioning and Rehabilitation (ASCR) staff realize that loaded time is likely to be a fraction of assigned ''exercise time'', this yield of loading is surprisingly low. Set-up and tear down represents a significant loss of time during a daily schedule in which there is high demand for station maintenance and science activities. Also, the ~43 minutes of loaded exercise is less than the ''2 hours of exercise''often quoted in the media, which is a misleading attribution that could result in an incorrect view of the effects of exercise countermeasures."

Alwood JS, Yumoto K, Mojarrab R, Limoli CL, Almeida EA, Searby ND, Globus RK. Heavy ion irradiation and unloading effects on mouse lumbar vertebral microarchitecture, mechanical properties and tissue stresses. Bone. 2010 May 11. [Epub ahead of print] (PIs: R.K. Globus; J.S. Alwood, NASA Graduate Student Researcher Program)

Villasana L, Pfankuch T, Raber J. Isoform-dependent effects of apoE on doublecortin-positive cells and microtubule-associated protein 2 immunoreactivity following (137)Cs irradiation. Radiat Environ Biophys. 2010 May 11. [Epub ahead of print] (PI: J. Raber)

Townsend LW, Charara YM, Delauder N, PourArsalan M, Anderson JA, Fisher CM, Spence HE, Schwadron NA, Golightly MJ, Cucinotta FA. Parameterizations of the linear energy transfer spectrum for the CRaTER instrument during the LRO mission. Space Weather. 2010 Mar;8:S00E03.

Schwadron NA, Townsend L, Kozarev K, Dayeh MA, Cucinotta F, Desai M, Golightly M, Hassler D, Hatcher R, Kim MY, Posner A, PourArsalan M, Spence HE, Squier RK. Earth-Moon-Mars Radiation Environment Module framework. Space Weather. 2010 Jan;8:S00E02.

Gooley JJ, Rajaratnam SM, Brainard GC, Kronauer RE, Czeisler CA, Lockley SW. Spectral responses of the human circadian system depend on the irradiance and duration of exposure to light. Sci Transl Med. 2010 May 12;2(31):31ra33. (PIs: G.C. Brainard, C.A. Czeisler, S.W. Lockley) Note: This article suggests that responses of the circadian system to light are more complicated than had been thought: a sensitivity to green light, as well as blue light, was demonstrated. The sensitivities depended on the timing, duration, and intensity of exposure. Two photoreceptor systems are involved. The article, which has received some media coverage, is featured on the cover of the journal.

Kass R, Kass J, Binder H, Kraft N. Conflict-handling mode scores of three crews before and after a 264-day spaceflight simulation. Aviat Space Environ Med. 2010 May;81(5):502-5.

Olson VA. The ecobiopolitics of space biomedicine. Med Anthropol. 2010 Apr;29(2):170-93.

Other papers of interest:

Chhabra S, Prasad AK. Flow and particle dispersion in a pulmonary alveolus--Part II: Effect of gravity on particle transport. J Biomech Eng. 2010 May;132(5):051010.

van Barneveld S, van der Palen J, van Putten MJ. Evaluation of the finger wrinkling test: A pilot study. Clin Auton Res. 2010 May 12. [Epub ahead of print] Note: This article may be obtained online without charge.

Habold C, Momken I, Ouadi A, Bekaert V, Brasse D. Effect of prior treatment with resveratrol on density and structure of rat long bones under tail-suspension. J Bone Miner Metab. 2010 May 11. [Epub ahead of print] Note: From abstract: "Resveratrol had a preventive effect against bone loss induced by hindlimb immobilization. In particular, trabecular bone in the proximal tibial metaphysis was totally preserved in rats treated with resveratrol before tail-suspension."

Pacifici R. T cells: Critical bone regulators in health and disease. Bone. 2010 May 7. [Epub ahead of print]

Crockett JC, Mellis DJ, Scott DI, Helfrich MH. New knowledge on critical osteoclast formation and activation pathways from study of rare genetic diseases of osteoclasts: Focus on the RANK/RANKL axis. Osteoporos Int. 2010 May 11. [Epub ahead of print]

Adachi T, Kameo Y, Hojo M. Trabecular bone remodelling simulation considering osteocytic response to fluid-induced shear stress. Philos Transact A Math Phys Eng Sci. 2010 Jun 13;368(1920):2669-82.

Knapp KM, Rowlands AV, Welsman JR, MacLeod KM. Prolonged unilateral disuse osteopenia 14 years post external fixator removal: A case history and critical review. Case Report Med. 2010;2010:629020. Epub 2010 Apr 21. Note: This article may be obtained online without charge in PubMed Central.

Cowin SC, Cardoso L. Fabric dependence of wave propagation in anisotropic porous media. Biomech Model Mechanobiol. 2010 May 12. [Epub ahead of print] Note: This article may be obtained online without charge.

Souza RB, Draper CE, Fredericson M, Powers CM. Femur rotation and patellofemoral joint kinematics: A weight-bearing magnetic resonance imaging analysis. J Orthop Sports Phys Ther. 2010 May;40(5):277-85.

Xie MJ, Ma YG, Gao F, Bai YG, Cheng JH, Chang YM, Yu ZB, Ma J. Activation of BKCa channel is associated with increased apoptosis of cerebrovascular smooth muscle cells in simulated microgravity rats. Am J Physiol Cell Physiol. 2010 Mar 24. [Epub ahead of print]

Fricke O, Beccard R, Semler O, Schoenau E. Analyses of muscular mass and function: The impact on bone mineral density and peak muscle mass. Pediatr Nephrol. 2010 May 11. [Epub ahead of print]

Krog J, Tonnesen EK, Jepsen CF, Parner E, Segadal K, Hope A, Ulvik RJ, Hokland ME. Natural killer cells as biomarkers of hyperbaric stress during a dry heliox saturation dive. Aviat Space Environ Med. 2010 May;81(5):467-74.

Dalecki M, Bock O, Guardiera S. Simulated flight path control of fighter pilots and novice subjects at +3 Gz in a human centrifuge. Aviat Space Environ Med. 2010 May;81(5):484-8.

Kennedy Q, Taylor JL, Reade G, Yesavage JA. Age and expertise effects in aviation decision making and flight control in a flight simulator. Aviat Space Environ Med. 2010 May;81(5):489-97.

Liu Y, Hu W, Wang H, Lu M, Shao C, Menzel C, Yan Z, Li Y, Zhao S, Khaitovich P, Liu M, Chen W, Barnes BM, Yan J. Genomic analysis of miRNAs in an extreme mammalian hibernator, the Arctic ground squirrel. Physiol Genomics. 2010 May 4. [Epub ahead of print]

Feng S, Wang Q, Wang H, Peng Y, Wang L, Lu Y, Shi T, Xiong L. Electroacupuncture pretreatment ameliorates hypergravity-induced impairment of learning and memory and apoptosis of hippocampal neurons in rats. Neurosci Lett. 2010 May 10. [Epub ahead of print]

Rodrigues EC, Lemos T, Gouvea B, Volchan E, Imbiriba LA, Vargas CD. Kinesthetic motor imagery modulates body sway. Neuroscience. 2010 May 10. [Epub ahead of print]

Simpson NS, Banks S, Dinges DF. Sleep restriction is associated with increased morning plasma leptin concentrations, especially in women. Biol Res Nurs. 2010 May 7. [Epub ahead of print]

Wang J, Katz E. Digital biosensors with built-in logic for biomedical applications--biosensors based on a biocomputing concept. Anal Bioanal Chem. 2010 May 13. [Epub ahead of print]

Pache C, Kuehn J, Westphal K, Toy MF, Parent JM, Buechi O, Franco-Obregon A, Depeursinge C, Egli M. Digital holographic microscopy real-time monitoring of cytoarchitectural alterations during simulated microgravity. J Biomed Opt. 2010 Mar-Apr;15(2):026021.

Hua SZ, Gottlieb PA, Heo J, Sachs F. A mechanosensitive ion channel regulating cell volume. Am J Physiol Cell Physiol. 2010 Jun;298(6):C1424-30. Epub 2010 Mar 24.

Popova AF, Ivanenko GF. Structural and cytochemical aspects of Brassica rapa L. embryogenesis under clinorotation. Cytol Genet. 2010 Apr;44(2):88-94. Note: This paper is a translation in English of the Russian original published in Tsitologiya i Genetika 2010;44(2):22-8.


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