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NASA Spaceline Current Awareness August 26, 2010

Status Report From: Spaceline
Posted: Thursday, August 26, 2010

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

Deegan BM, Devine ER, Geraghty MC, Jones E, OLaighin G, Serrador JM. The relationship between cardiac output and dynamic cerebral autoregulation in humans. J Appl Physiol. 2010 Aug 5. [Epub ahead of print] (PI: J.M. Serrador)

Gregg CJ, Steppan J, Gonzalez DR, Champion HC, Phan AC, Nyhan D, Shoukas AA, Hare JM, Barouch LA, Berkowitz DE. {beta}2-Adrenergic receptor-coupled phosphoinositide 3-kinase constrains cAMP-dependent increases in cardiac inotropy through phosphodiesterase 4 activation. Anesth Analg. 2010 Aug 12. [Epub ahead of print] (PI: A.A. Shoukas)

Yuvaraj S, Blanchard JJ, Daughtridge G, Kolb RJ, Shanmugarajan S, Bateman TA, Reddy SV. Microarray profile of gene expression during osteoclast differentiation in modeled microgravity. J Cell Biochem. 2010 Aug 17. [Epub ahead of print]

Cengel KA, Diffenderfer ES, Avery S, Kennedy AR, McDonough J. Using electron beam radiation to simulate the dose distribution for whole body solar particle event proton exposure. Radiat Environ Biophys. 2010 Aug 20. [Epub ahead of print] (PI: A.R. Kennedy/K.A. Cengel/Center for Acute Radiation Research)

Das AK, Bell MH, Nirodi CS, Story MD, Minna JD. Radiogenomics predicting tumor responses to radiotherapy in lung cancer. Semin Radiat Oncol. 2010 Jul;20(3):149-55. (PI: J.D. Minna/M.D. Story/NSCOR)

Stoelen MF, Akin DL. Assessment of Fitts' law for quantifying combined rotational and translational movements. Hum Factors. 2010 Feb;52(1):63-77.

Simpson NS, Banks S, Arroyo S, Dinges DF. Effects of sleep restriction on adiponectin levels in healthy men and women. Physiol Behav. 2010 Aug 17. [Epub ahead of print] (PI: D.F. Dinges)

Skardal A, Sarker SF, Crabbe A, Nickerson CA, Prestwich GD. The generation of 3-D tissue models based on hyaluronan hydrogel-coated microcarriers within a rotating wall vessel bioreactor. Biomaterials. 2010 Aug 7. [Epub ahead of print] (PI: C.A. Nickerson)

Other papers of interest:

Broderick BJ, Corley GJ, Quondamatteo F, Breen PP, Serrador JM, OLaighin G. Venous emptying from the foot. Influences of weight-bearing, toe-curls, electrical stimulation, passive compression and posture. J Appl Physiol. 2010 Aug 12. [Epub ahead of print]

Zhou X, Wang JL, Lu J, Song Y, Kwak KS, Jiao Q, Rosenfeld R, Chen Q, Boone T, Simonet WS, Lacey DL, Goldberg AL, Han HQ. Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival. Cell. 2010 Aug 20;142(4):531-43. Note: This potentially significant research is featured on the cover of the journal. Use the magnifying glass under the image to look at this cute cover. Author Alfred Goldberg is a former PI.

Altaeva EG, Lysenko LA, Kantserova NP, Nemova NN, Shenkman BS. The basal calcium level in fibers of the rat soleus muscle under gravitational unloading: The mechanisms of its increase and the role in calpain activation. Dokl Biol Sci. 2010 Jul-Aug;433:241-3. Epub 2010 Aug 17. Note: Hindlimb suspension was used. This paper is a translation in English of the Russian original published in Doklady Akademii Nauk 2010;433(1):138-41.

Gorgiladze GI. Morphological features of the inertial mass in statocysts of the terrestrial gastropods Helix lucorum and Pomatias rivulare exposed to microgravity. Dokl Biol Sci. 2010 Jul-Aug;433:271-4. Epub 2010 Aug 17. Note: ISS results. This paper is a translation in English of the Russian original published in Doklady Akademii Nauk 2010;433(4):566-9.

Varenik EN, Lipina TV, Shornikova MV, Krasnov IB, Chentzov YS. The structure of the rat left ventricular myocardium in models of microgravity and artificial gravitation. Dokl Biol Sci. 2010 Jul-Aug;433:286-8. Epub 2010 Aug 17. Note: Hindlimb suspension and centrifugation were used. This paper is a translation in English of the Russian original published in Doklady Akademii Nauk 2010;433(3):423-5.

Price C, Zhou X, Li W, Wang L. Real-time measurement of solute transport within the lacunar-canalicular system of mechanically loaded bone: Direct evidence for load-induced fluid flow. J Bone Miner Res. 2010 Aug 16. [Epub ahead of print]

Kamel MA, Picconi JL, Lara-Castillo N, Johnson ML. Activation of beta-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE(2): Implications for the study of mechanosensation in bone. Bone. 2010 Aug 14. [Epub ahead of print]

Kulkarni RN, Bakker AD, Everts V, Klein-Nulend J. Inhibition of osteoclastogenesis by mechanically loaded osteocytes: Involvement of MEPE. Calcif Tissue Int. 2010 Aug 20. [Epub ahead of print] Note: This article may be obtained online without charge.

Hind K, Oldroyd B, Truscott JG. In vivo precision of the GE Lunar iDXA Densitometer for the measurement of total-body, lumbar spine, and femoral bone mineral density in adults. J Clin Densitom. 2010 Aug 12. [Epub ahead of print]

Gorbunova AV. [Effects of space-flight factors on cytochemical characteristics of the motor analyzer neurons] Vestn Ross Akad Med Nauk. 2010;(5):15-21. Russian. Note: Cosmos 605, Cosmos 782, Cosmos 936 results.

Afonso N, Amponsah D, Yang J, Mendez J, Bridge P, Hays G, Baliga S, Crist K, Brennan S, Jackson M, Dulchavsky S. Adding new tools to the black bag--Introduction of ultrasound into the physical diagnosis course. J Gen Intern Med. 2010 Aug 10. [Epub ahead of print]

Cassola VF, Kramer R, Brayner C, Khoury HJ. Posture-specific phantoms representing female and male adults in Monte Carlo-based simulations for radiological protection. Phys Med Biol. 2010 Aug 7;55(15):4399-430. Epub 2010 Jul 20.

Hubbard TL, Courtney JR. Cross-modal influences on representational momentum and representational gravity. Perception. 2010;39(6):851-62.

Gao H, Liu M, Zhuo Y, Zhou X, Liu J, Chen D, Zhang W, Gou Z, Shang P, Zhang L. Assessing the potential of an induced-mutation strategy for avermectin overproducers. Appl Environ Microbiol. 2010 Jul;76(13):4583-6. Epub 2010 May 7. Note: A ground simulation of microgravity was done with a high-magnetogravitational experimental platform using a large gradient superconducting magnet.

Moore SW, Roca-Cusachs P, Sheetz MP. Stretchy proteins on stretchy substrates: The important elements of integrin-mediated rigidity sensing. Dev Cell. 2010 Aug 17;19(2):194-206.

Matthews BD, Thodeti CK, Tytell JD, Mammoto A, Overby DR, Ingber DE. Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins. Integr Biol (Camb). 2010 Aug 20. [Epub ahead of print]


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