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NASA Spaceline Current Awareness October 1, 2010

Status Report From: Spaceline
Posted: Friday, October 1, 2010

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.Lam H, Hu M, Qin YX. Alteration of contraction-to-rest ratio to optimize trabecular bone adaptation induced by dynamic muscle stimulation. Bone. 2010 Sep 17. [Epub ahead of print] (PI: Y.X. Qin)

Cheng J, Lu JY, Lin W, Qin YX. A new algorithm for spatial impulse response of rectangular planar transducers. Ultrasonics. 2010 Sep 4. [Epub ahead of print] (PI: Y.X. Qin)

Mukherjee B, Choy H, Nirodi C, Burma S. Targeting nonhomologous end-joining through epidermal growth factor receptor inhibition: Rationale and strategies for radiosensitization. Semin Radiat Oncol. 2010 Oct;20(4):250-7. (PI: S. Burma)

Chun MG, Mao JH, Chiu CW, Balmain A, Hanahan D. Polymorphic genetic control of tumor invasion in a mouse model of pancreatic neuroendocrine carcinogenesis. Proc Natl Acad Sci U S A. 2010 Sep 20. [Epub ahead of print] (PI: A. Balmain) Note: This article may be obtained online without charge.

Schoenfeld MP, Ansari RR, Zakrajsek JF, Billiar TR, Toyoda Y, Wink DA, Nakao A. Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight. Med Hypotheses. 2010 Sep 20. [Epub ahead of print]

Zhou G, Smilenov LB, Lieberman HB, Ludwig T, Hall EJ. Radiosensitivity to high energy iron ions is influenced by heterozygosity for Atm, Rad9 and Brca1. Adv Space Res. 2010 Sep 15;46(6):681-6. (PI: E.J. Hall) Note: This article and 13 other articles in this list are part of a "Life Sciences in Space" issue. Three other articles from the issue are not included in this list. The Table of Contents can be viewed by clicking on the volume and issue at the upper left of the publisher's abstract.

Badavi FF, Adams DO, Wilson JW. On the validity of the aluminum equivalent approximation in space radiation shielding applications. Adv Space Res. 2010 Sep 15;46(6):719-27.

Zeitlin C, Guetersloh S, Heilbronn L, Miller J, Fukumura A, Iwata Y, Murakami T, Sihver L. Nuclear fragmentation database for GCR transport code development. Adv Space Res. 2010 Sep 15;46(6):728-34. (PI: C. Zeitlin)

Slaba TC, Blattnig SR, Clowdsley MS, Walker SA, Badavi FF. An improved neutron transport algorithm for HZETRN. Adv Space Res. 2010 Sep 15;46(6):800-10.

Patel OV, Casey T, Dover H, Plaut K. Homeorhetic adaptation to lactation: Comparative transcriptome analysis of mammary, liver, and adipose tissue during the transition from pregnancy to lactation in rats. Funct Integr Genomics. 2010 Sep 18. [Epub ahead of print] (PI: K. Plaut)

Massa GD, Santini JB, Mitchell CA. Minimizing energy utilization for growing strawberries during long-duration space habitation. Adv Space Res. 2010 Sep 15;46(6):735-43. (PI: C.A. Mitchell/NSCORT)

Thomas EA, Weislogel MM, Klaus DM. Design considerations for sustainable spacecraft water management systems. Adv Space Res. 2010 Sep 15;46(6):761-7.

Other papers of interest:

Hinghofer-Szalkay H. Gravity, the hydrostatic indifference concept and the cardiovascular system. Eur J Appl Physiol. 2010 Sep 21. [Epub ahead of print]

Rakobowchuk M, Crozier J, Glover EI, Yasuda N, Phillips SM, Tarnopolsky MA, Macdonald MJ. Short-term unilateral leg immobilization alters peripheral but not central arterial structure and function in healthy young humans. Eur J Appl Physiol. 2010 Sep 18. [Epub ahead of print] Note: Knee brace immobilization was used.

Belavy DL, Armbrecht G, Gast U, Richardson CA, Hides JA, Felsenberg D. Countermeasures against lumbar spine deconditioning in prolonged bed-rest: Resistive exercise with and without whole-body vibration. J Appl Physiol. 2010 Sep 23. [Epub ahead of print] Note: Second Berlin Bed Rest Study.

Tian X, Jee WS, Li X, Paszty C, Ke HZ. Sclerostin antibody increases bone mass by stimulating bone formation and inhibiting bone resorption in a hindlimb-immobilization rat model. Bone. 2010 Sep 17. [Epub ahead of print] Note: Some of the authors work for Amgen, who partly funded the study.

Kapur S, Amoui M, Kesavan C, Wang X, Mohan S, Baylink DJ, Lau KH. Leptin receptor (LEPR) is a negative modulator of bone mechanosensitivity and genetic variations in LEPR may contribute to the differential osteogenic response to mechanical stimulation in the C57BL/6J and C3H/HeJ pair of mouse strains. J Biol Chem. 2010 Sep 17. [Epub ahead of print] Note: This article may temporarily be obtained online without charge.

Wang H, Young SR, Gerard-O'Riley R, Hum JM, Yang Z, Bidwell JP, Pavalko FM. Blockade of TNFR1 signaling: A role of oscillatory fluid shear stress in osteoblasts. J Cell Physiol. 2010 Sep 20. [Epub ahead of print]

Nowlan NC, Jepsen KJ, Morgan EF. Smaller, weaker, and less stiff bones evolve from changes in subsistence strategy. Osteoporos Int. 2010 Sep 21. [Epub ahead of print] Note: A caution for human evolution.

Jackson JR, Ryan MJ, Hao Y, Alway SE. Mediation of endogenous antioxidant enzymes and apoptotic signaling by resveratrol following muscle disuse in the gastrocnemius muscles of young and old rats. Am J Physiol Regul Integr Comp Physiol. 2010 Sep 22. [Epub ahead of print]

Mukai R, Nakao R, Yamamoto H, Nikawa T, Takeda E, Terao J. Quercetin prevents unloading-derived disused muscle atrophy by attenuating the induction of ubiquitin ligases in tail-suspension mice. J Nat Prod. 2010 Sep 20. [Epub ahead of print]

Hvid LG, Aagaard P, Justesen L, Bayer ML, Andersen JL, Ortenblad N, Kjaer M, Suetta C. Effects of aging on muscle mechanical function and muscle fiber morphology during short-term immobilization and subsequent retraining. J Appl Physiol. 2010 Sep 23. [Epub ahead of print] Note: Cast immobilization was used.

Nielsen J, Suetta C, Hvid LG, Schroder HD, Aagaard P, Ortenblad N. Subcellular localization dependent decrements in skeletal muscle glycogen and mitochondria content following short-term disuse in young and old men. Am J Physiol Endocrinol Metab. 2010 Sep 21. [Epub ahead of print]

Leskinen T, Rinnankoski-Tuikka R, Rintala M, Seppaenen-Laakso T, Poellaenen E, Alen M, Sipilae S, Kaprio J, Kovanen V, Rahkila P, Oresic M, Kainulainen H, Kujala UM. Differences in muscle and adipose tissue gene expression and cardio-metabolic risk factors in the members of physical activity discordant twin pairs. PLoS One. 2010 Sep 16;5(9). pii: e12609. Note: This article may be obtained online without charge.

Nugent S, Mothersill CE, Seymour C, McClean B, Lyng FM, Murphy JE. Altered mitochondrial function and genome frequency post exposure to gamma-radiation and bystander factors. Int J Radiat Biol. 2010 Oct;86(10):829-41.

Klammer H, Kadhim M, Iliakis G. Evidence of an adaptive response targeting DNA non-homologous end joining and its transmission to bystander cells. Cancer Res. 2010 Sep 22. [Epub ahead of print]

Zaconte V, Casolino M, De Santis C, Di Fino L, La Tessa C, Larosa M, Narici L, Picozza P. The radiation environment in the ISS-USLab measured by ALTEA: Spectra and relative nuclear abundances in the polar, equatorial and SAA regions. Adv Space Res. 2010 Sep 15;46(6):797-9. Note: ISS results.

Yang A, Yang C, Ke P. Modeling and verification of an astronaut handling large-mass payload. Ch J Mech Eng. 2010 Aug;23(4):517-23.

Qian AR, Yang PF, Hu LF, Zhang W, Di SM, Wang Z, Han J, Gao X, Shang P. High magnetic gradient environment causes alterations of cytoskeleton and cytoskeleton-associated genes in human osteoblasts cultured in vitro. Adv Space Res. 2010 Sep 15;46(6):687-700.

Zhao C, Sun Y, Yi ZC, Rong L, Zhuang FY, Fan YB. Simulated microgravity inhibits cell wall regeneration of Penicillium decumbens protoplasts. Adv Space Res. 2010 Sep 15;46(6):701-6.

dos Santos MA, Bosquillon C, Russomano T, Sundaresan A, Falcao F, Marriott C, Forbes B. Modelling the effects of microgravity on the permeability of air interface respiratory epithelial cell layers. Adv Space Res. 2010 Sep 15;46(6):712-8.

Thompson MS, Abercrombie SR, Ott CE, Bieler FH, Duda GN, Ventikos Y. Quantification and significance of fluid shear stress field in biaxial cell stretching device. Biomech Model Mechanobiol. 2010 Sep 18. [Epub ahead of print]

Song MJ, Dean D, Knothe Tate ML. In situ spatiotemporal mapping of flow fields around seeded stem cells at the subcellular length scale. PLoS One. 2010 Sep 17;5(9). pii: e12796. Note: This article may be obtained online without charge.

Toyota M, Morita MT. [Re-examination of starch-statolith hypothesis, a model for gravity sensing mechanism in plants] Seikagaku. 2010 Aug;82(8):730-4. Japanese.

Johnson IR, Thornley JH, Frantz JM, Bugbee B. A model of canopy photosynthesis incorporating protein distribution through the canopy and its acclimation to light, temperature and CO2. Ann Bot. 2010 Sep 22. [Epub ahead of print]

Tikhomirov AA, Kudenko YA, Ushakova SA, Tirranen LS, Gribovskaya IA, Gros J-B, Lasseur C. Use of human wastes oxidized to different degrees in cultivation of higher plants on the soil-like substrate intended for closed ecosystems. Adv Space Res. 2010 Sep 15;46(6):744-50.

Tang Y, Guo S, Dong W, Qin L, Ai W, Lin S. Effects of long-term low atmospheric pressure on gas exchange and growth of lettuce. Adv Space Res. 2010 Sep 15;46(6):751-60.

Balnokin Y, Myasoedov N, Popova L, Tikhomirov A, Ushakova S, Lasseur C, Gros J-B. Use of halophytic plants for recycling NaCl in human liquid waste in a bioregenerative life support system. Adv Space Res. 2010 Sep 15;46(6):768-74.

Polyakov YS, Musaev I, Polyakov SV. Closed bioregenerative life support systems: Applicability to hot deserts. Adv Space Res. 2010 Sep 15;46(6):775-86.

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