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NASA Spaceline Current Awareness February 4, 2011

Status Report From: Spaceline
Posted: Friday, February 4, 2011

The abstract in PubMed or at the publisher's site is linked when available and will open in a new window.

Muir J, Judex S, Qin YX, Rubin C. Postural instability caused by extended bed rest is alleviated by brief daily exposure to low magnitude mechanical signals. Gait Posture. 2011 Jan 26. [Epub ahead of print] (PI: C. Rubin) Note: The bed rest study was conducted at the NASA bed rest facility at the University of Texas Medical Branch, Galveston.

Cheng J, Lin W, Qin YX. Extension of the distributed point source method for ultrasonic field modeling. Ultrasonics. 2010 Dec 30. [Epub ahead of print] (PI: Y-X. Qin)

Khan-Mayberry N, James J, Tyl R, Lam CW. Space toxicology: Protecting human health during space operations. Int J Toxicol. 2011 Jan 25. [Epub ahead of print] (PIs: J. James, C.W. Lam) Note: This article is a summary of a symposium "Space Toxicology: Human Health During Space Operations," held at the American College of Toxicology annual meeting. It covers a range of issues in space toxicology.

Groesser T, Chang H, Fontenay G, Chen J, Costes SV, Barcellos-Hoff MH, Parvin B, Rydberg B. Persistence of gamma-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to gamma-rays or iron ions. Int J Radiat Biol. 2011 Jan 27. [Epub ahead of print] (PI: M.H. Barcellos-Hoff)

Templin T, Amundson SA, Brenner DJ, Smilenov LB. Whole mouse blood microRNA as biomarkers for exposure to gamma-rays and (56)Fe ions. Int J Radiat Biol. 2011 Jan 28. [Epub ahead of print] (PI: L.B. Smilenov)

Kanakaraj I, Jewell DL, Murphy JC, Fox GE, Willson RC. Removal of PCR error products and unincorporated primers by metal-chelate affinity chromatography. PLoS One. 2011 Jan 14;6(1):e14512. (PI: G.E. Fox) Note: This article may be obtained online without charge.

Chang R, Emami K, Wu H, Sun W. Biofabrication of a three-dimensional liver micro-organ as an in vitro drug metabolism model. Biofabrication. 2010 Dec;2(4):045004. Epub 2010 Nov 15. Note: From paper: "The conducted collaborative research herein between NASA-JSC and Drexel University was specifically intended to explore the development and study of a space flight-suitable in vitro three-dimensional microfluidic microanalytical microorgan device (3MD) for the simulation of human response to drug administrations and toxic chemical exposures under microgravity and space environments." See the following citation also.

Chang RC, Emami K, Jeevarajan A, Wu H, Sun W. Microprinting of liver micro-organ for drug metabolism study. Methods Mol Biol. 2011;671:219-38.

de Silva K, Laska B, Brown C, Sederoff HW, Khodakovskaya M. Arabidopsis thaliana calcium-dependent lipid-binding protein (AtCLB): A novel repressor of abiotic stress response. J Exp Bot. 2011 Jan 20. [Epub ahead of print]

Other papers of interest:

Karlsson LL, Rohdin M, Nekludov M, Ax M, Petersson J. No protective role for hypoxic pulmonary vasoconstriction in severe hypergravity-induced arterial hypoxemia. Eur J Appl Physiol. 2011 Jan 15. [Epub ahead of print]

Lightfoot JT. Current understanding of the genetic basis for physical activity. J Nutr. 2011 Jan 26. [Epub ahead of print]

Reed SA, Senf SM, Cornwell EW, Kandarian SC, Judge AR. Inhibition of IkappaB kinase alpha (IKKalpha) or IKKbeta (IKKbeta) plus forkhead box O (Foxo) abolishes skeletal muscle atrophy. Biochem Biophys Res Commun. 2011 Jan 21. [Epub ahead of print]

Murphy KT, Cobani V, Ryall JG, Ibebunjo C, Lynch GS. Acute antibody-directed myostatin inhibition attenuates disuse muscle atrophy and weakness in mice. J Appl Physiol. 2011 Jan 26. [Epub ahead of print]

Reichart DL, Hinkle RT, Lefever FR, Dolan ET, Dietrich JA, Sibley DR, Isfort RJ. Activation of the dopamine 1 and dopamine 5 receptors increase skeletal muscle mass and force production under non-atrophying and atrophying conditions. BMC Musculoskelet Disord. 2011 Jan 26;12:27. [Epub ahead of print] Note: This article may be obtained online without charge.

Romero-Rodriguez D, Gual G, Tesch PA. Efficacy of an inertial resistance training paradigm in the treatment of patellar tendinopathy in athletes: A case-series study. Phys Ther Sport. 2011 Feb;12(1):43-8. Epub 2010 Dec 10. Note: This article (html may be the only free version) may be obtained online without charge. Find the issue and article.

McCarthy EF. Perspective: Skeletal complications of space flight. Skeletal Radiol. 2011 Jan 26. [Epub ahead of print] Note: This article may temporarily be obtained online without charge.

He JY, Jiang LS, Dai LY. The roles of the sympathetic nervous system in osteoporotic diseases: A review of experimental and clinical studies. Ageing Res Rev. 2011 Jan 22. [Epub ahead of print]

Rieger R, Hambli R, Jennane R. Modeling of biological doses and mechanical effects on bone transduction. J Theor Biol. 2011 Apr 7;274(1):36-42.

Farthing JP, Krentz JR, Magnus CR, Barss TS, Lanovaz JL, Cummine J, Esopenko C, Sarty GE, Borowsky R. Changes in fMRI cortical activation with cross-education to an immobilized limb. Med Sci Sports Exerc. 2011 Jan 21. [Epub ahead of print]

Ohkawara K, Oshima Y, Hikihara Y, Ishikawa-Takata K, Tabata I, Tanaka S. Real-time estimation of daily physical activity intensity by a triaxial accelerometer and a gravity-removal classification algorithm. Br J Nutr. 2011 Jan 25:1-11. [Epub ahead of print]

Bouma HR, Kroese FG, Kok JW, Talaei F, Boerema AS, Herwig A, Draghiciu O, van Buiten A, Epema AH, van Dam A, Strijkstra AM, Henning RH. Low body temperature governs the decline of circulating lymphocytes during hibernation through sphingosine-1-phosphate. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2052-7. Epub 2011 Jan 18.

Stieler JT, Bullmann T, Kohl F, Toien O, Brueckner MK, Haertig W, Barnes BM, Arendt T. The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation. PLoS One. 2011 Jan 18;6(1):e14530. Note: These researchers are investigating the phosphorylation and reversal of phosphorylation of tau protein in certain hibernating species. The research may be relevant to Alzheimer's disease. This article may be obtained online without charge.

Carabe-Fernandez A, Dale RG, Paganetti H. Repair kinetic considerations in particle beam radiotherapy. Br J Radiol. 2011 Jan 25. [Epub ahead of print]

Tomilovskaya ES, Kozlovskaya IB. Effects of long-term space flights on the organization of the horizontal gaze fixation reaction. Hum Physiol. 2010 Nov;36(6):708-15. Note: Mir results. This paper is a translation in English of the Russian original published in Fiziologiya Cheloveka 2010 Nov-Dec;36(6):104-12.

Rolfs M, Jonikaitis D, Deubel H, Cavanagh P. Predictive remapping of attention across eye movements. Nat Neurosci. 2011 Feb;14(2):252-6. Epub 2010 Dec 26. Note: A comment on this paper by Krauzlis and Nummela states: "Our perception of the visual world is stable despite saccade-caused retinal input shifts. A new behavioral study shows that this stability may be achieved by predictively remapping attention before eye movements begin."

Tagliabue M, McIntyre J. Necessity is the mother of invention: Reconstructing missing sensory information in multiple, concurrent reference frames for eye-hand coordination. J Neurosci. 2011 Jan 26;31(4):1397-409. Note: This issue has an attractive cover.

Meng R, Xu HY, Di SM, Shi DY, Qian AR, Wang JF, Shang P. Human mesenchymal stem cells are sensitive to abnormal gravity and exhibit classic apoptotic features. Acta Biochim Biophys Sin (Shanghai). 2011 Feb;43(2):133-42.

Myers KA, Applegate KT, Danuser G, Fischer RS, Waterman CM. Distinct ECM mechanosensing pathways regulate microtubule dynamics to control endothelial cell branching morphogenesis. J Cell Biol. 2011 Jan 24;192(2):321-34.

Brenner MD, Zhou R, Ha T. Forcing a connection: Impacts of single-molecule force spectroscopy on in vivo tension sensing. Biopolymers. 2011 Jan 25. [Epub ahead of print]






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