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NASA Spaceline Current Awareness 13 April 2012 (Recent Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, April 13, 2012

image

Papers deriving from NASA support:

1
Galpin AJ, Raue U, Jemiolo B, Trappe TA, Harber MP, Minchev K, Trappe S.
Human skeletal muscle fiber type specific protein content.
Anal Biochem. 2012 Mar 30. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22469996
(PI: S. Trappe)

2
Bhadra SJ, Ebner AD, Ritter JA.
On the use of the dual process Langmuir model for predicting unary and binary isosteric heats of adsorption.
Langmuir. 2012 Apr 5. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22480343
(PI: J.A. Ritter)

3
Zhang J, de Toledo SM, Pandey BN, Guo G, Pain D, Li H, Azzam EI.
Role of the translationally controlled tumor protein in DNA damage sensing and repair.
Proc Natl Acad Sci U S A. 2012 Mar 26. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22451927
(PI: E.I. Azzam)

4
Wiese C, Rudolph JH, Jakob B, Fink D, Tobias F, Blattner C, Taucher-Scholz G.
PCNA-dependent accumulation of CDKN1A into nuclear foci after ionizing irradiation.
DNA Repair (Amst). 2012 Mar 26. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22456500
(PI: C. Wiese)

5
Grabham P, Bigelow A, Geard C.
DNA damage foci formation and decline in 2-dimensional monolayers and in 3-dimensional human vessel models: Differential effects according to radiation quality.
Int J Radiat Biol. 2012 Mar 26. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22449005
(PI: C.R. Geard)

6
Mehrotra S, Pecaut MJ, Freeman TL, Crapo JD, Rizvi A, Luo-Owen X, Slater JM, Gridley DS.
Analysis of a metalloporphyrin antioxidant mimetic (MnTE-2-PyP) as a radiomitigator: Prostate tumor and immune status.
Technol Cancer Res Treat. 2012 Mar 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22475066

7
Schoenfeld MP, Ansari RR, Nakao A, Wink D.
A hypothesis on biological protection from space radiation through the use of new therapeutic gases as medical counter measures.
Med Gas Res. 2012 Apr 4;2:8. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22475015
NOTE: This article may be obtained online without charge.

8
Small RL, Oman CM, Jones TD.
Space shuttle flight crew spatial orientation survey results.
Aviat Space Environ Med. 2012 Apr;83(4):383-7.
http://www.ncbi.nlm.nih.gov/pubmed/22462365
(PI: R.L. Small)

9
Morris TR, Cho C, Dilda V, Shine JM, Naismith SL, Lewis SJ, Moore ST.
A comparison of clinical and objective measures of freezing of gait in Parkinson's disease.
Parkinsonism Relat Disord. 2012 Mar 23. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22445248
(PI: S.T. Moore)

10
Kiss JZ, Millar KD, Edelmann RE.
Phototropism of Arabidopsis thaliana in microgravity and fractional gravity on the International Space Station.
Planta. 2012 Apr 6. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22481136
(PI: J.Z. Kiss)
NOTE: ISS results.

Other papers of interest:

1
Zuj KA, Arbeille P, Shoemaker JK, Blaber AP, Greaves DK, Xu D, Hughson RL.
Impaired cerebrovascular autoregulation and reduced CO2 reactivity after long duration spaceflight.
Am J Physiol Heart Circ Physiol. 2012 Apr 6. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22492717
NOTE: ISS results.

2
Moralez G, Romero SA, Rickards CA, Ryan KL, Convertino VA, Cooke WH.
Effects of dehydration on cerebrovascular control during standing after heavy resistance exercise.
J Appl Physiol. 2012 Mar 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22461441

3
Chung SY, Kim SK, Hong CW, Oh KW, Kim KT, Sul JG, Chung JW, Kwon MS.
The time-dependent alteration of anti-diuretic hormone system in hindlimb unloaded rats.
J Physiol Pharmacol. 2012 Feb;63(1):87-94.
http://www.ncbi.nlm.nih.gov/pubmed/22460465
NOTE: This article may be obtained online without charge: http://www.jpp.krakow.pl/journal/archive/02_12/pdf/87_02_12_article.pdf

4
Monsuez JJ, Beddok R, Mahiou A, Ngaleu A, Belbachir S.
[Orthostatic hypotension: Epidemiology and mechanisms]
Presse Med. 2012 Mar 21. [Epub ahead of print] French.
http://www.ncbi.nlm.nih.gov/pubmed/22445241

5
Cote AT, Bredin SS, Phillips AA, Warburton DE.
Predictors of orthostatic intolerance in healthy young women.
Clin Invest Med. 2012 Apr 1;35(2):E65.
http://www.ncbi.nlm.nih.gov/pubmed/22469106

6
Mader TH, Gibson CR, Pass AF.
Regarding "Diurnal Pattern of Intraocular Pressure is Affected by Microgravity When Measured in Space With the Pressure Phosphene Tonometer."
J Glaucoma. 2012 Apr 6. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22495070
NOTE: This letter comments on a specific point in an earlier article with the above title (PMID: 21968970). The letter is temporarily available online without charge: http://dx.doi.org/10.1097/IJG.0b013e318252d5af
The response to this letter is below.

7
Woo SJ, Kim TW, Chung KY.
Intraocular Pressure Elevation During Space Flight.
J Glaucoma. 2012 Apr 6. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22495071
NOTE: This letter, a response to the letter above, is temporarily available online without charge: http://dx.doi.org/10.1097/IJG.0b013e318252d5cb

8
Shinojima A, Iwasaki K, Aoki K, Ogawa Y, Yanagida R, Yuzawa M.
Subfoveal choroidal thickness and foveal retinal thickness during head-down tilt.
Aviat Space Environ Med. 2012 Apr;83(4):388-93.
http://www.ncbi.nlm.nih.gov/pubmed/22462366

9
Arbeille P, Zuj K, Shoemaker K, Hughson R.
Temporal artery Doppler spectrum morphology responses to tilt and LBNP as an early indicator of syncope.
Aviat Space Environ Med. 2012 Apr;83(4):394-402.
http://www.ncbi.nlm.nih.gov/pubmed/22462367

10
Poh PY, Armstrong LE, Casa DJ, Pescatello LS, McDermott BP, Emmanuel H, Maresh CM.
Orthostatic hypotension after 10 days of exercise-heat acclimation and 28 hours of sleep loss.
Aviat Space Environ Med. 2012 Apr;83(4):403-11.
http://www.ncbi.nlm.nih.gov/pubmed/22462368

11
Marco RA, Stuckey RM, Holloway SP.
Prolonged bed rest as adjuvant therapy after complex reconstructive spine surgery.
Clin Orthop Relat Res. 2012 Mar 31. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22467418
NOTE: The authors discuss the effects of prolonged bed rest on musculoskeletal deterioratation but they judged it less important than post-surgery complications. This article may temporarily be obtained online without charge.

12
Etheridge T, Nemoto K, Hashizume T, Mori C, Sugimoto T, Suzuki H, Fukui K, Yamazaki T, Higashibata A, Szewczyk NJ, Higashitani A.
The next phase of life-sciences spaceflight research: Harnessing the power of functional genomics.
Commun Integr Biol. 2011 Nov-Dec;4(6):668-9.
http://www.ncbi.nlm.nih.gov/pubmed/22446523
NOTE: This article may be obtained online without charge via PubMed Central and at the publisher's site.

13
Carey HV, Martin SL, Horwitz BA, Yan L, Bailey SM, Podrabsky J, Storz JF, Ortiz RM, Wong RP, Lathrop DA.
Elucidating nature's solutions to heart, lung, and blood diseases and sleep disorders.
Circ Res. 2012 Mar 30;110(7):915-21.
http://www.ncbi.nlm.nih.gov/pubmed/22461362
NOTE: This article may temporarily be obtained online without charge.

14
Sandona D, Desaphy JF, Camerino GM, Bianchini E, Ciciliot S, Danieli-Betto D, Dobrowolny G, Furlan S, Germinario E, Goto K, Gutsmann M, Kawano F, Nakai N, Ohira T, Ohno Y, Picard A, Salanova M, Schiffl G, Blottner D, Musaro A, Ohira Y, Betto R, Conte D, Schiaffino S.
Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission.
PLoS One. 2012;7(3):e33232. Epub 2012 Mar 28.
http://www.ncbi.nlm.nih.gov/pubmed/22470446
NOTE: ISS results. This article may be obtained online without charge.

15
Gast U, John S, Runge M, Rawer R, Felsenberg D, Belavy DL.
Short-duration resistive exercise sustains neuromuscular function after bed rest.
Med Sci Sports Exerc. 2012 Mar 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22460472
NOTE: Second Berlin Bed Rest Study.

16
Veselova OM, Ogneva IV, Larina IM.
Effects of long-term microgravitation exposure on cell respiration of the rat musculus soleus fibers.
Bull Exp Biol Med. 2011 Jul;151(3):318-20. English, Russian.
http://www.ncbi.nlm.nih.gov/pubmed/22451876
NOTE: This paper is an English translation from Byulleten' Eksperimental'noi Biologii i Meditsiny 2011 Mar;151(3):292-4. The term "microgravitation" in the title refers to hindlimb suspension.

17
Lundberg TR, Fernandez-Gonzalo R, Gustafsson T, Tesch PA.
Aerobic exercise alters skeletal muscle molecular responses to resistance exercise.
Med Sci Sports Exerc. 2012 Mar 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22460475

18
Russ DW, Gregg-Cornell K, Conaway MJ, Clark BC.
Evolving concepts on the age-related changes in "muscle quality".
J Cachexia Sarcopenia Muscle. 2012 Feb 3. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22476917
NOTE: This article may be obtained online without charge.

19
Clark BC, Manini TM.
What is dynapenia?
Nutrition. 2012 May;28(5):495-503.
http://www.ncbi.nlm.nih.gov/pubmed/22469110

20
Powers SK, Smuder AJ, Judge AR.
Oxidative stress and disuse muscle atrophy: Cause or consequence?
Curr Opin Clin Nutr Metab Care. 2012 Mar 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22466926

21
Pedersen BK, Febbraio MA.
Muscles, exercise and obesity: Skeletal muscle as a secretory organ.
Nat Rev Endocrinol. 2012 Apr 3. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22473333

22
Park H, Kong SY, Kim HW, Yang IH.
Altered cellular kinetics in growth plate according to alterations in weight bearing.
Yonsei Med J. 2012 May;53(3):618-24.
http://www.ncbi.nlm.nih.gov/pubmed/22477008
NOTE: This article may be obtained online without charge.

23
Stelzeneder D, Kovacs BK, Goed S, Welsch GH, Hirschfeld C, Paternostro-Sluga T, Friedrich KM, Mamisch TC, Trattnig S.
Effect of short-term unloading on T2 relaxation time in the lumbar intervertebral disc--in vivo magnetic resonance imaging study at 3.0 tesla.
Spine J. 2012 Mar;12(3):257-64.
http://www.ncbi.nlm.nih.gov/pubmed/22469305
NOTE: This article may be obtained online without charge.

24
Van Houdt R, Mijnendonckx K, Leys N.
Microbial contamination monitoring and control during human space missions.
Planet Space Sci. 2012 Jan;60(1):115-20.
http://dx.doi.org/10.1016/j.pss.2011.09.001
NOTE: This review article summarizes issues of microbial contamination on ISS, including standards, procedures, and results. The article may be obtained online without charge.

25
Bilski P, Berger T, Hajek M, Reitz G.
Comparison of the response of various TLDs to cosmic radiation and ion beams: Current results of the HAMLET project.
Radiat Meas. 2011 Dec;46(12):1680-5.
http://dx.doi.org/10.1016/j.radmeas.2011.03.023
NOTE: ISS results.

26
Pinsky L, Stoffle N, Empl A, Jakubek J, Pospisil S, Leroy C, Kitamura H, Yasuda N, Uchihori Y.
Application of the Medipix2 technology to space radiation dosimetry and hadron therapy beam monitoring.
Radiat Meas. 2011 Dec;46(12):1610-4.
http://dx.doi.org/10.1016/j.radmeas.2011.08.026

27
Pukkala E, Helminen M, Haldorsen T, Hammar N, Kojo K, Linnersjoe A, Rafnsson V, Tulinius H, Tveten U, Auvinen A.
Cancer incidence among Nordic airline cabin crew.
Int J Cancer. 2012 Mar 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22447246

28
Napadow V, Sheehan JD, Kim J, LaCount LT, Park K, Kaptchuk TJ, Rosen BR, Kuo B.
The brain circuitry underlying the temporal evolution of nausea in humans.
Cereb Cortex. 2012 Apr 2. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22473843

29
Boulanger M, Galiana HL, Guitton D.
Human eye-head gaze shifts preserve accuracy and spatiotemporal trajectory profiles despite long-duration torque perturbations that assist or oppose head motion.
J Neurophysiol. 2012 Mar 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22457469

30
Chang NY, Uchanski RM, Hullar TE.
Temporal integration of auditory and vestibular stimuli.
Laryngoscope. 2012 Apr 3. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22473616

31
Ferre ER, Bottini G, Haggard P.
Vestibular inputs modulate somatosensory cortical processing.
Brain Struct Funct. 2012 Apr 1. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22466455

32
Stooke-Vaughan GA, Huang P, Hammond KL, Schier AF, Whitfield TT.
The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle.
Development. 2012 Mar 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22461562

33
Ricci MA, Brumsted JR.
Crew resource management: Using aviation techniques to improve operating room safety.
Aviat Space Environ Med. 2012 Apr;83(4):441-4.
http://www.ncbi.nlm.nih.gov/pubmed/22462374

34
Farges B, Poughon L, Roriz D, Creuly C, Dussap CG, Lasseur C.
Axenic cultures of Nitrosomonas europaea and Nitrobacter winogradskyi in autotrophic conditions: A new protocol for kinetic studies.
Appl Biochem Biotechnol. 2012 Mar 27. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22451350
NOTE: This study is part of ESA's MELiSSA project.

35
Tinkerhess MJ, Ginzberg S, Piazza N, Wessells RJ.
Endurance training protocol and longitudinal performance assays for Drosophila melanogaster.
J Vis Exp. 2012 Mar 26;(61). pii: 3786.
http://www.ncbi.nlm.nih.gov/pubmed/22472601
NOTE: Fruit fly workouts. The article and video may be obtained online without charge.

36
Consolo F, Bariani C, Mantalaris A, Montevecchi F, Redaelli A, Morbiducci U.
Computational modeling for the optimization of a cardiogenic 3D bioprocess of encapsulated embryonic stem cells.
Biomech Model Mechanobiol. 2012 Jan;11(1-2):261-77. Epub 2011 Apr 23.
http://www.ncbi.nlm.nih.gov/pubmed/21516431

37
Downs ME, Nguyen AM, Herzog FA, Hoey DA, Jacobs CR.
An experimental and computational analysis of primary cilia deflection under fluid flow.
Comput Methods Biomech Biomed Engin. 2012 Mar 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22452422

38
Noguera R, Nieto OA, Tadeo I, Farinas F, Alvaro T.
Extracellular matrix, biotensegrity and tumor microenvironment. An update and overview.
Histol Histopathol. 2012 Jun;27(6):693-705.
http://www.ncbi.nlm.nih.gov/pubmed/22473691

39
Jones TJ, Nauli SM.
Mechanosensory calcium signaling.
Adv Exp Med Biol. 2012;740:1001-15.
http://www.ncbi.nlm.nih.gov/pubmed/22453981

40
Hara M, Tabata K, Suzuki T, Do MK, Mizunoya W, Nakamura M, Nishimura S, Tabata S, Ikeuchi Y, Sunagawa K, Anderson JE, Allen RE, Tatsumi R.
Calcium influx through a possible coupling of cation channels impacts skeletal muscle satellite cell activation in response to mechanical stretch.
Am J Physiol Cell Physiol. 2012 Mar 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22460715


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