NASA Spaceline Current Awareness 27 April 2012 (Recent Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, April 27, 2012


Papers deriving from NASA support:

Macias BR, D'Lima DD, Cutuk A, Patil S, Steklov N, Neuschwander TB, Meuche S, Colwell CW Jr., Hargens AR.
Leg intramuscular pressures and in vivo knee forces during lower body positive and negative pressure treadmill exercise.
J Appl Physiol. 2012 Apr 26. [Epub ahead of print]
(PI: A.R. Hargens)

Morris C, Tomimatsu N, Richard DJ, Cluet D, Burma S, Khanna KK, Jalinot P.
INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells.
Cancer Res. 2012 Apr 15;72(8):2006-16.
(PI: S. Burma)

Trani D, Moon BH, Kallakury B, Hartmann DP, Datta K, Fornace AJ Jr.
Sex-dependent differences in intestinal tumorigenesis induced in Apc1638N/+ mice by exposure to rays.
Int J Radiat Oncol Biol Phys. 2012 Apr 12. [Epub ahead of print]
(PIs: A.J. Fornace; A.J. Fornace/K. Datta/NSCOR; D. Trani, NSBRI Postdoctoral Fellowship Program)

He Z, Mangala LS, Theriot CA, Rohde LH, Wu H, Zhang Y.
Cell killing and radiosensitizing effects of atorvastatin in PC3 prostate cancer cells.
J Radiat Res. 2012;53(2):225-33.
NOTE: This article may be obtained online without charge.

Weerts AP, De Meyer G, Pauwels G, Vanspauwen R, Dornhoffer JL, Van de Heyning PH, Wuyts FL.
Pharmaceutical countermeasures have opposite effects on the utricles and semicircular canals in man.
Audiol Neurootol. 2012 Apr 19;17(4):235-42. [Epub ahead of print]
(PI: J.L. Dornhoffer)

Buxton OM, Cain SW, O'Connor SP, Porter JH, Duffy JF, Wang W, Czeisler CA, Shea SA.
Adverse metabolic consequences in humans of prolonged sleep restriction combined with circadian disruption.
Sci Transl Med. 2012 Apr 11;4(129):129ra43.
(PI: C.A. Czeisler)

Klerman H, St. Hilaire MA, Kronauer RE, Gooley JJ, Gronfier C, Hull JT, Lockley SW, Santhi N, Wang W, Klerman EB.
Analysis method and experimental conditions affect computed circadian phase from melatonin data.
PLoS One. 2012;7(4):e33836. Epub 2012 Apr 12.
(PIs: S.W. Lockley, C.A. Czeisler)
NOTE: This article may be obtained online without charge.

Choi WG, Swanson SJ, Gilroy S.
High-resolution imaging of Ca(2+), redox status, ROS and pH using GFP biosensors.
Plant J. 2012 Apr;70(1):118-28.
(PI: S. Gilroy)
NOTE: This article may be obtained online without charge.

Other papers of interest:

Bergouignan A, Habold C, Rudwill F, Gauquelin-Koch G, Normand S, Simon C, Blanc S.
Urinary C-peptide is not an accurate bioindicator of energy balance in humans.
Obesity (Silver Spring). 2012 Mar;20(3):683-8. Epub 2011 May 12.
NOTE: WISE-2005 bed rest study.

Gao F, Cheng JH, Bai YG, Boscolo M, Huang XF, Zhang X, Zhang LF.
Mechanical properties and composition of mesenteric small arteries of simulated microgravity rats with and without daily -G(x) gravitation.
Sheng Li Xue Bao. 2012 Apr 25;64(2):107-20.
NOTE: This article may be obtained online without charge. The translated title of the journal is Acta Physiologica Sinica.

Cote AT, Phillips AA, Bredin SS, Warburton DE.
A questionable association of stroke volume and arterial pulse pressure under gravitational stress.
J Trauma Acute Care Surg. 2012 Mar;72(3):708-12.

Fedorowski A, Franceschini N, Brody J, Liu C, Verwoert GC, Boerwinkle E, Couper D, Rice KM, Rotter JI, Raso FM, Uitterlinden A, Hofman A, Almgren P, Sjoegren M, Hedblad B, Larson MG, Newton-Cheh C, Wang TJ, Rose KM, Psaty BM, Levy D, Witteman J, Melander O.
Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium.
Eur Heart J. 2012 Apr 14. [Epub ahead of print]
NOTE: This article may be obtained online without charge.

Mereu R, De Barbieri G, Perrone T, Mugellini A, Di Toro A, Bernardi L.
Heart rate/blood pressure ratio as predictor of neuromediated syncope.
Int J Cardiol. 2012 Apr 12. [Epub ahead of print]

Malinin NL, Pluskota E, Byzova TV.
Integrin signaling in vascular function.
Curr Opin Hematol. 2012 May;19(3):206-11.

Goel M, Sienkiewicz AE, Picciani R, Wang J, Lee RK, Bhattacharya SK.
Cochlin, intraocular pressure regulation and mechanosensing.
PLoS One. 2012;7(3):e34309. Epub 2012 Apr 4.
NOTE: This article may be obtained online without charge.

Kashif FM, Verghese GC, Novak V, Czosnyka M, Heldt T.
Model-based noninvasive estimation of intracranial pressure from cerebral blood flow velocity and arterial pressure.
Sci Transl Med. 2012 Apr 11;4(129):129ra44.

Wu CW, Storey KB.
Pattern of cellular quiescence over the hibernation cycle in liver of thirteen-lined ground squirrels.
Cell Cycle. 2012 May 1;11(9):1714-26.

Tessier SN, Storey KB.
Myocyte enhancer factor-2 and cardiac muscle gene expression during hibernation in thirteen-lined ground squirrels.
Gene. 2012 Apr 6. [Epub ahead of print]

Matusitz J, McCormick J.
Sedentarism: The effects of internet use on human obesity in the United States.
Soc Work Public Health. 2012 Mar 29;27(3):250-69.

Pottage T, Macken S, Giri K, Walker JT, Bennett AM.
Low temperature decontamination for space applications -- A comparison of hydrogen peroxide and chlorine dioxide.
Appl Environ Microbiol. 2012 Apr 6. [Epub ahead of print]

Kachaeva EV, Shenkman BS.
Various jobs of proteolytic enzymes in skeletal muscle during unloading: Facts and speculations.
J Biomed Biotechnol. 2012;2012:493618. Epub 2012 Feb 8.
NOTE: This article may be obtained online without charge.

Chao YH, Tsuang YH, Sun JS, Magaret, Chen MH.
Centrifugal force induces human ligamentum flavum fibroblasts inflammation through activation of JNK and p38 pathway.
Connect Tissue Res. 2012 Apr 16. [Epub ahead of print]

Amonette WE, Brown LE, De Witt JK, Dupler TL, Tran TT, Tufano JJ, Spiering BA.
Peak vertical jump power estimations in youths and young adults.
J Strength Cond Res. 2012 Apr 10. [Epub ahead of print]

Kemmler W, von Stengel S.
Alternative exercise technologies to fight against sarcopenia at old age: A series of studies and review.
J Aging Res. 2012;2012:109013. Epub 2012 Feb 20.
NOTE: This article may be obtained online without charge.

Swift SN, Baek K, Swift JM, Bloomfield SA.
Restriction of dietary energy intake has a greater impact on bone integrity than does restriction of calcium in exercising female rats.
J Nutr. 2012 Apr 18. [Epub ahead of print]

Silva MJ, Brodt MD, Lynch MA, Stephens AL, Wood DJ, Civitelli R.
Tibial loading increases osteogenic gene expression and cortical bone volume in mature and middle-aged mice.
PLoS One. 2012;7(4):e34980. Epub 2012 Apr 13.
NOTE: This article may be obtained online without charge.

Carew EO.
A semi-empirical cell dynamics model for bone turnover under external stimulus.
J Biomech Eng. 2012 Feb;134(2):024503.

Tsuda S, Sato T, Takahashi F, Satoh D, Sasaki S, Namito Y, Iwase H, Ban S, Takada M.
Systematic measurement of lineal energy distributions for proton, He and Si Ion beams over a wide energy range using a wall-less tissue equivalent proportional counter.
J Radiat Res. 2012;53(2):264-71.
NOTE: This article may be obtained online without charge.

Akudugu JM, Azzam EI, Howell RW.
Induction of lethal bystander effects in human breast cancer cell cultures by DNA-incorporated iodine-125 depends on phenotype.
Int J Radiat Biol. 2012 Apr 10. [Epub ahead of print]

Smith JT, Willey NJ, Hancock JT.
Low dose ionizing radiation produces too few reactive oxygen species to directly affect antioxidant concentrations in cells.
Biol Lett. 2012 Apr 11. [Epub ahead of print]

Laube R, Govender S, Colebatch JG.
Vestibular-dependent spinal reflexes evoked by brief lateral accelerations of the heads of standing subjects.
J Appl Physiol. 2012 Apr 5. [Epub ahead of print]

Wang SJ, Jaw FS, Young YH.
Correlation between acceleration magnitude and ocular vestibular-evoked myogenic potential.
Neurosci Lett. 2012 May 10;516(1):75-8.

Hirashima M, Nozaki D.
Distinct motor plans form and retrieve distinct motor memories for physically identical movements.
Curr Biol. 2012 Mar 6;22(5):432-6. Epub 2012 Feb 8.

Dickin DC, McClain MA, Hubble RP, Doan JB, Sessford D.
Changes in postural sway frequency and complexity in altered sensory environments following whole body vibrations.
Hum Mov Sci. 2012 Apr 17. [Epub ahead of print]

Ichijo H.
Is horizontal semicircular canal ocular reflex influenced by otolith organs input?
Acta Otolaryngol. 2012 Apr 12. [Epub ahead of print]

Rai B, Foing BH, Kaur J.
Working hours, sleep, salivary cortisol, fatigue and neuro-behavior during Mars analog mission: Five crews study.
Neurosci Lett. 2012 Mar 31. [Epub ahead of print]
NOTE: Mars Desert Research Station study.

Ding XF, Liu MY, Guo XH, Zhu YY, Wu PL, Guan Y.
[Analysis of Atractylodes macrocephala koidz of spaceflight breeding with XRF and PXRD]
Guang Pu Xue Yu Guang Pu Fen Xi. 2012 Feb;32(2):545-7. Chinese.
NOTE: Chinese satellite results. The translated title of the journal is Spectroscopy and Spectral Analysis.

Rosado H, O'Neill AJ, Blake KL, Walther M, Long PF, Hinds J, Taylor PW.
Rotating wall vessel exposure alters protein secretion and global gene expression in Staphylococcus aureus.
Int J Astrobiol. 2012 Apr;11(2):71-81.

Radtke AL, Herbst-Kralovetz MM.
Culturing and applications of rotating wall vessel bioreactor derived 3D epithelial cell models.
J Vis Exp. 2012 Apr 3;(62). pii: 3868.
NOTE: The article may be obtained online without charge but the video is not free.

Mohan K, Iglesias PA, Robinson DN.
Separation anxiety: Stress, tension and cytokinesis.
Exp Cell Res. 2012 Mar 31. [Epub ahead of print]

Trichet L, Le Digabel J, Hawkins RJ, Vedula SR, Gupta M, Ribrault C, Hersen P, Voituriez R, Ladoux B.
Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness.
Proc Natl Acad Sci U S A. 2012 Apr 16. [Epub ahead of print]

Chehab EW, Yao C, Henderson Z, Kim S, Braam J.
Arabidopsis touch-induced morphogenesis is jasmonate mediated and protects against pests.
Curr Biol. 2012 Apr 24;22(8):701-6.

Grimard M.
Will the US remain the real leader of human space exploration? A comparative assessment of space exploration policies.
Acta Astronaut. 2012 Jun-Jul;75:1-14.
NOTE: "Highlights" (from the publisher's site abstract or the TOC):
Analysis of human space exploration dynamics in USA, Russia, China, Europe, Japan and India.
USA has the largest civil space budget, but is no longer trusted as a leader due to its evasiveness.
Europe and Japan are in a wait and see mode, human space exploration is not a real priority. Russia is wealthy, but the priorities are more on space for the benefit of the nation's development.
China has high ambitions in space and human space exploration, and the resources to realise.

Tomilovskaya ES.
[Experiment with 5-day dry immersion: Objectives, content and structure of the investigations, methods]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):3-7. Russian.
NOTE: The 13 articles in this issue report results of a 5-day dry immersion experiment.

Kornilova LN, Naumov IA, Glukhikh DO.
[Visual-manual tracking during 5-day dry immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):8-12. Russian.

Pastuchkova LK, Pakharukova NA, Trifonova OP, Dobrokhotov IV, Valeeva OA, Larina IM.
[Direct proteome profiling of human blood serum in the experiment with 5-day dry immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):13-8. Russian.

Vorontsov AL, Nesterovskaya AY, Morukov BV, Markin AA, Zhuravleva OA, Zabolotskaya IV, Vostrikova LV.
[Dynamics of the protein content of human urine during 5-day immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):18-21. Russian.

Noskov VB, Larina IM, Pastushkova LK, Dobrokhotov IV, Valeeva OA, Coupe M, Custaud MA, Novoselova AM.
[Renal functioning and human body liquids during 5-day dry immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):22-6. Russian.

Popova YA, Suvorov AV, Diachenko AI, Kolesnikov VI.
[Biomechanics and regulation of the external respiration in the conditions of 5-day dry immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):26-31. Russian.

Mikhailovskaya AN, Osipova AA, Diachenko AI.
[Acoustic and spirometric indices of forced expiration noise in the conditions of 5-day dry immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):32-6. Russian.

Semenov YS, Popova YA, Diachenko AI, Reushkina GD, Kolesnikov VI, Suvorov AV.
[Characteristics of negative pressure inspiration effect on the cardiorespiratory system of humans in the conditions of 5-day dry immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):37-40. Russian.

Mardanov RG, Orlov OI, Tsarkov DS, Mukhamedieva LN.
[Volatile metabolites in expired air of humans during 5-day dry immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):41-3. Russian.

Ivanov GG, Baevsky RM, Bersenev EY, Rusanov VB, Larina IM, Pastushkova LK.
[Indices of electrocardiogram dispersion mapping during 5-day exposure in dry immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):44-8. Russian.

Ivanova SM, Morukov BV, Labetskaya OI, Yarlykova YV.
[Examination of the morphofunctional properties of red blood cells of humans in 5-day dry immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):49-51. Russian.

Afonin BV, Sedova EA, Goncharova NP, Solovieva AA.
[Investigation of the evacuatory function of the gastrointestinal tract in 5-day dry immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):52-7. Russian.

Nichiporuk IA, Vasilieva GY, Rykova MP, Antropova EN, Berendeeva TA, Ponomarev SA, Morukov BV.
[Analysis of the relationships between the psychophysiological status and system of adaptive immunity in the conditions of 5-day dry immersion]
Aviakosm Ekolog Med. 2011 Nov-Dec;45(6):57-63. Russian.

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