NASA Spaceline Current Awareness 10 February 2012 (Recent Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, February 10, 2012


Papers deriving from NASA support:

Zwart SR, Gibson CR, Mader TH, Ericson K, Ploutz-Snyder R, Heer M, Smith SM.
Vision changes after spaceflight are related to alterations in folate- and vitamin B-12-dependent one-carbon metabolism.
J Nutr. 2012 Feb 1. [Epub ahead of print]
(PI: S.M. Smith)
NOTE: ISS results.

Zwart SR, Jessup JM, Ji J, Smith SM.
Saturation diving alters folate status and biomarkers of DNA damage and repair.
PLoS One. 2012;7(2):e31058. Epub 2012 Feb 7.
(PI: S.R. Zwart)
NOTE: NEEMO 14 results. This article may be obtained online without charge.

Wei B, Abobo CV, Ma J, Liang D.
Gender differences in pharmacokinetics of antipyrine in a simulated weightlessness rat model.
Aviat Space Environ Med. 2012 Jan;83(1):8-13.
(PI: T.R. Bates)

Metts JG, Klaus DM.
First-order feasibility analysis of a space suit radiator concept based on estimation of water mass sublimation using Apollo mission data.
Adv Space Res. 2012 Jan 1;49(1):204-12.
(PI: J.G. Metts, NASA Graduate Student Researcher Program)
NOTE: Used Apollo data. This article may be obtained online without charge when obtained via the Table of Contents.

Duda KR, Jarchow T, Young LR.
Squat exercise biomechanics during short-radius centrifugation.
Aviat Space Environ Med. 2012 Feb;83(2):102-10.
(PI: L.R. Young)

Kerstman EL, Scheuring RA, Barnes MG, DeKorse TB, Saile LG.
Space adaptation back pain: A retrospective study.
Aviat Space Environ Med. 2012 Jan;83(1):2-7.
NOTE: Review of astronaut data from multiple flight programs, from Mercury to ISS.

Etheridge T, Oczypok EA, Lehmann S, Fields BD, Shephard F, Jacobson LA, Szewczyk NJ.
Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans.
PLoS Genet. 2012 Jan;8(1):e1002471. Epub 2012 Jan 12.
NOTE: This article may be obtained online without charge.

Wilson JM, Krigsfeld GS, Sanzari JK, Wagner EB, Mick R, Kennedy AR.
Comparison of hindlimb unloading and partial weight suspension models for spaceflight-type condition induced effects on white blood cells.
Adv Space Res. 2012 Jan 15;49(2):237-48.
(PI: A.R. Kennedy/Center of Acute Radiation Research)

Wang M, Hada M, Huff J, Pluth JM, Anderson J, O'Neill P, Cucinotta FA.
Heavy ions can enhance TGF mediated epithelial to mesenchymal transition.
J Radiat Res (Tokyo). 2012;53(1):51-7.
(PIs: J. Huff, J.M. Pluth, F.A. Cucinotta)
NOTE: This article may be obtained online without charge.

Chatterjee A, Diordieva I, Yumoto K, Globus RK, Bhattacharya S.
Protein array profiling of mouse serum, six months post whole body radiation with (56)Fe.
J Toxicol Sci. 2012 Feb;37(1):215-7.
(PI: R.K. Globus)
NOTE: This article may be obtained online without charge.

Bahadori AA, Van Baalen M, Shavers MR, Semones EJ, Bolch WE.
Dosimetric impacts of microgravity: An analysis of 5th, 50th and 95th percentile male and female astronauts.
Phys Med Biol. 2012 Feb 1;57(4):1047-70. [Epub ahead of print]
(PI: A.A. Bahadori, NASA Graduate Student Researcher Program)

Cummings CS, Lucas EM, Marro JA, Kieu TM, DesJardins JD.
The effects of proton radiation on UHMWPE material properties for space flight and medical applications.
Adv Space Res. 2011 Nov 15;48(10):1572-7.

Basner M, Dinges DF.
An adaptive-duration version of the PVT accurately tracks changes in psychomotor vigilance induced by sleep restriction.
Sleep. 2012 Feb 1;35(2):193-202.
(PI: D.F. Dinges)

Massa GD, Mitchell CA.
Sweetpotato vine management for confined food production in a space life-support system.
Adv Space Res. 2012 Jan 15;49(2):262-70.
(PI: C.A. Mitchell)

Doarn CR, Angotti C, Cooper L.
Development of Occupational Health at NASA: Five decades of progress.
J Occup Environ Med. 2012 Jan 26. [Epub ahead of print]

Other papers of interest:

Gillis DB, Hamilton DR.
Estimating outcomes of astronauts with myocardial infarction in exploration class space missions.
Aviat Space Environ Med. 2012 Feb;83(2):79-91.

Wiener TC.
Space obstructive syndrome: Intracranial hypertension, intraocular pressure, and papilledema in space.
Aviat Space Environ Med. 2012 Jan;83(1):64-6.

Hachiya T, Hashimoto I, Saito M, Blaber AP.
Peripheral vascular responses of men and women to LBNP.
Aviat Space Environ Med. 2012 Feb;83(2):118-24.

Gennser M, Jurd KM, Blogg SL.
Pre-dive exercise and post-dive evolution of venous gas emboli.
Aviat Space Environ Med. 2012 Jan;83(1):30-4.

Mukundakrishnan K, Ayyaswamy PS, Eckmann DM.
Computational simulation of hematocrit effects on arterial gas embolism dynamics.
Aviat Space Environ Med. 2012 Feb;83(2):92-101.

Kneller W, Higham P, Hobbs M.
Measuring manual dexterity and anxiety in divers using a novel task at 35-41 m.
Aviat Space Environ Med. 2012 Jan;83(1):54-7.

Thiel CS, Paulsen K, Bradacs G, Lust K, Tauber S, Dumrese C, Hilliger A, Schoppmann K, Biskup J, Goelz N, Sang C, Ziegler U, Grote KH, Zipp F, Zhuang F, Engelmann F, Hemmersbach R, Cogoli A, Ullrich O.
Rapid alterations of cell cycle control proteins in human T lymphocytes in microgravity.
Cell Commun Signal. 2012 Jan 24;10:1.
NOTE: Parabolic flight results. This article may be obtained online without charge.

Saqib KM, Rahman ZU, Nagra SA.
Effect of weightlessness on neutrophils and lymphocytes of rats.
Pakistan Vet J. 2012 Jan-Mar;32(1):25-30.
NOTE: This article may be obtained online without charge.

Guo F, Li Y, Liu Y, Huang J, Zhang Z, Wang J, Li Y, Hu J, Li G.
Identification of genes associated with tumor development in CaSki cells in the cosmic space.
Mol Biol Rep. 2012 Feb 4. [Epub ahead of print]
NOTE: Shenzhou 4 results.

Groemer GE, Hauth S, Luger U, Bickert K, Sattler B, Hauth E, Foeger D, Schildhammer D, Agerer C, Ragonig C, Sams S, Kaineder F, Knoflach M.
The Aouda.X space suit simulator and its applications to astrobiology.
Astrobiology. 2012 Feb 2. [Epub ahead of print]

Rantalainen T, Ruotsalainen I, Virmavirta M.
Effect of weighted vest suit worn during daily activities on running speed, jumping power and agility in young men.
J Strength Cond Res. 2012 Jan 20. [Epub ahead of print]
NOTE: Wearing a weighted vest is termed "hypergravity" in this abstract.

Raue U, Trappe TA, Estrem ST, Qian HR, Helvering LM, Smith RC, Trappe SW.
Transcriptome signature of resistance exercise adaptations: Mixed muscle and fiber type specific profiles in young and old adults.
J Appl Physiol. 2012 Feb 2. [Epub ahead of print]

Caruso JF, Borgsmiller JA, Riner RD, Mason ML, Lutz BR, Nelson CC.
Net energy expenditure of gravity-independent high-speed resistive exercise done by women.
Aviat Space Environ Med. 2012 Feb;83(2):111-7.

Crane JD, Ogborn DI, Cupido C, Melov S, Hubbard A, Bourgeois JM, Tarnopolsky MA.
Massage therapy attenuates inflammatory signaling after exercise-induced muscle damage.
Sci Transl Med. 2012 Feb 1;4(119):119ra13.

Atkins GJ, Findlay DM.
Osteocyte regulation of bone mineral: A little give and take.
Osteoporos Int. 2012 Feb 3. [Epub ahead of print]

Liotier PJ, Rossi JM, Wendling-Mansuy S, Chabrand P.
Trabecular bone remodelling under pathological conditions based on biochemical and mechanical processes involved in BMU activity.
Comput Methods Biomech Biomed Engin. 2012 Jan 30. [Epub ahead of print]

Wu ZH, Zhang H, Wang XY, Yang R, Liu B, Liu Y, Zhao WP, Feng HY, Xue LG, Hao JF, Niu BT, Wang ZH.
Protective effects of melatonin against 12C6+ beam irradiation-induced oxidative stress and DNA injury in the mouse brain.
Adv Space Res. 2012 Jan 1;49(1):196-203.
NOTE: This article may be obtained online without charge when obtained via the Table of Contents.

Koliskova (Mrazova) Z, Sihver L, Ambroova I, Sato T, Spurn F, Shurshakov VA.
Simulations of absorbed dose on the phantom surface of MATROSHKA-R experiment at the ISS.
Adv Space Res. 2012 Jan 15;49(2):230-6.
NOTE: ISS results.

Shi L, Oberdoerffer P.
Chromatin dynamics in DNA double-strand break repair.
Biochim Biophys Acta. 2012 Jan 16. [Epub ahead of print]

Bringoux L, Blouin J, Coyle T, Ruget H, Mouchnino L.
Effect of gravity-like torque on goal-directed arm movements in microgravity.
J Neurophysiol. 2012 Feb 1. [Epub ahead of print]
NOTE: Parabolic flight results.

Klein TJ, Jeka J, Kiemel T, Lewis MA.
Navigating sensory conflict in dynamic environments using adaptive state estimation.
Biol Cybern. 2011 Dec;105(5-6):291-304. Epub 2012 Jan 31.

Xie SJ, Chen W, Jia HB, Wang ZJ, Yao Q, Jiang YY.
Ocular vestibular evoked myogenic potentials and motion sickness susceptibility.
Aviat Space Environ Med. 2012 Jan;83(1):14-8.

Dubey VN, Agrawal SK.
Study of an upper arm exoskeleton for gravity balancing and minimization of transmitted forces.
Proc Inst Mech Eng H. 2011 Nov;225(11):1025-35.

Simons-Morton BG, Zhang Z, Jackson JC, Albert PS.
Do elevated gravitational-force events while driving predict crashes and near crashes?
Am J Epidemiol. 2012 Jan 23. [Epub ahead of print]

Biernacki MP, Jankowski KS, Kowalczuk K, Lewkowicz R, Dere M.
+Gz centrifugation and mood.
Aviat Space Environ Med. 2012 Feb;83(2):136-9.

Vigo DE, Ogrinz B, Wan L, Bersenev E, Tuerlinckx F, Van Den Bergh O, Aubert AE.
Sleep-wake differences in heart rate variability during a 105-day simulated mission to Mars.
Aviat Space Environ Med. 2012 Feb;83(2):125-30.

Dodd MD, Balzer A, Jacobs CM, Gruszczynski MW, Smith KB, Hibbing JR.
The political left rolls with the good and the political right confronts the bad: Connecting physiology and cognition to preferences.
Philos Trans R Soc Lond B Biol Sci. 2012 Mar 5;367(1589):640-9.
NOTE: Can science help understand the differences? This article is part of an interesting issue on the topic: "The biology of cultural conflict," with a free introduction:

Herranz R, Larkin OJ, Dijkstra CE, Hill RJ, Anthony P, Davey MR, Eaves L, van Loon JJ, Medina FJ, Marco R.
Microgravity simulation by diamagnetic levitation: Effects of a strong gradient magnetic field on the transcriptional profile of Drosophila melanogaster.
BMC Genomics. 2012 Feb 1;13:52. [Epub ahead of print]
NOTE: This article may be obtained online without charge.

Li P, Ma YC, Sheng XY, Dong HT, Han H, Wang J, Xia YY.
Cyclic fluid shear stress promotes osteoblastic cells proliferation through ERK5 signaling pathway.
Mol Cell Biochem. 2012 Jan 28. [Epub ahead of print]

Salameh A, Dhein S.
Effects of mechanical forces and stretch on intercellular gap junction coupling.
Biochim Biophys Acta. 2012 Jan 4. [Epub ahead of print]
NOTE: Many articles are currently being published on mechanobiology and mechanosensing, due to new technologies and the growing relevance to such topics as cancer and development, as well as gravitational biology. A few sample articles are included in each list. Similarly, there are more articles on whole-body vibration, often tested as a possible treatment for a disease state as well as physiological improvement; these articles are generally not included in these lists. Additional articles can be viewed in PubMed or other databases by using such search terms as "mechano*" and "whole-body vibration".

Mou B.
Mutations in lettuce improvement.
Int J Plant Genomics. 2011;2011:723518. Epub 2012 Jan 11.
NOTE: This article contains a paragraph about obtaining lettuce mutants from space flight. The article may be obtained online without charge via PubMed Central.

Saltykov MY, Bartsev SI, Lankin YP.
Stability of Closed Ecology Life Support Systems (CELSS) models as dependent upon the properties of metabolism of the described species.
Adv Space Res. 2012 Jan 15;49(2):223-9.

Tikhomirov A, Kudenko Y, Trifonov S, Ushakova S.
Assessing the feasibility of involving gaseous products resulting from physicochemical oxidation of human liquid and solid wastes in the cycling of a bio-technical life support system.
Adv Space Res. 2012 Jan 15;49(2):249-53.

Farges B, Duchez D, Dussap CG, Cornet JF.
Preliminary characterization of carbon dioxide transfer in a hollow fiber membrane module as a possible solution for gas-liquid transfer in microgravity conditions.
Adv Space Res. 2012 Jan 15;49(2):254-61.

Hao Z, Li D, Li Y, Wang Z, Xiao Y, Wang G, Liu Y, Hu C, Liu Q.
Nostoc sphaeroides Kuetzing, an excellent candidate producer for CELSS.
Adv Space Res. 2011 Nov 15;48(10):1565-71.

Ehrenfreund P, McKay C, Rummel JD, Foing BH, Neal CR, Masson-Zwaan T, Ansdell M, Peter N, Zarnecki J, Mackwell S, Perino MA, Billings L, Mankins J, Race M.
Toward a global space exploration program: A stepping stone approach.
Adv Space Res. 2012 Jan 1;49(1):2-48.
NOTE: This article may be obtained online without charge when obtained via the Table of Contents.

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