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NASA Spaceline Current Awareness 9 December 2011 (Recent Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, December 9, 2011

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Papers deriving from NASA support:

1
Androjna C, McCabe NP, Cavanagh PR, Midura RJ.
Effects of spaceflight and skeletal unloading on bone fracture healing.
Clin Rev Bone Miner Metab. 2011 Feb 1. [Epub ahead of print]
http://dx.doi.org/10.1007/s12018-011-9080-z
(PI: R.J. Midura)
NOTE: Review of this topic.

2
Doarn CR.
Medical policy development for human spaceflight at NASA: An evolution.
Aviat Space Environ Med. 2011 Nov;82(11):1073-7.
http://www.ncbi.nlm.nih.gov/pubmed/22097646

3
Khokhlova TD, Canney MS, Khokhlova VA, Sapozhnikov OA, Crum LA, Bailey MR.
Controlled tissue emulsification produced by high intensity focused ultrasound shock waves and millisecond boiling.
J Acoust Soc Am. 2011 Nov;130(5):3498-510.
http://www.ncbi.nlm.nih.gov/pubmed/22088025
(PI: L.A. Crum)

4
Kreider W, Crum LA, Bailey MR, Sapozhnikov OA.
A reduced-order, single-bubble cavitation model with applications to therapeutic ultrasound.
J Acoust Soc Am. 2011 Nov;130(5):3511-30.
http://www.ncbi.nlm.nih.gov/pubmed/22088026
(PI: L.A. Crum)

5
Kreider W, Crum LA, Bailey MR, Sapozhnikov OA.
Observations of the collapses and rebounds of millimeter-sized lithotripsy bubbles.
J Acoust Soc Am. 2011 Nov;130(5):3531-40.
http://www.ncbi.nlm.nih.gov/pubmed/22088027
(PI: L.A. Crum)

6
Carra C, Cucinotta FA.
Accurate prediction of the binding free energy and analysis of the mechanism of the interaction of replication protein A (RPA) with ssDNA.
J Mol Model. 2011 Nov 25. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22116609
(PI: F.A. Cucinotta)

7
Lebel EA, Rusek A, Sivertz MB, Yip K, Thompson KH, Tafrov ST.
Analyses of the secondary particle radiation and the DNA damage it causes to human keratinocytes.
J Radiat Res (Tokyo). 2011;52(6):685-93.
http://www.ncbi.nlm.nih.gov/pubmed/22104266
(PI: S.T. Tafrov)
NOTE: This article may be obtained online without charge.

8
Liu X, Li F, Stubblefield EA, Blanchard B, Richards TL, Larson GA, He Y, Huang Q, Tan AC, Zhang D, Benke TA, Sladek JR, Zahniser NR, Li CY.
Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells.
Cell Res. 2011 Nov 22. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22105488
(PI: C.Y. Li)
NOTE: This article may be obtained online without charge.

9
Soehner AM, Kennedy KS, Monk TH.
Circadian preference and sleep-wake regularity: Associations with self-report sleep parameters in daytime-working adults.
Chronobiol Int. 2011 Nov;28(9):802-9.
http://www.ncbi.nlm.nih.gov/pubmed/22080786
(PI: T.H. Monk)

10
Oczypok EA, Etheridge T, Freeman J, Stodieck L, Johnsen R, Baillie D, Szewczyk NJ.
Remote automated multi-generational growth and observation of an animal in low Earth orbit.
J R Soc Interface. 2011 Nov 30. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22130552
(PI: C. Conley)
NOTE: ISS results. This article may be obtained online without charge.

11
He C, Davies FT Jr.
Ethylene reduces plant gas exchange and growth of lettuce grown from seed to harvest under hypobaric and ambient total pressure.
J Plant Physiol. 2011 Nov 26. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22118875
(PI: F.T. Davies)

Other papers of interest:

1
Hughson RL, Shoemaker JK, Blaber AP, Arbeille P, Greaves DK, Pereira-Junior PP, Xu D.
Cardiovascular regulation during long-duration spaceflights to the International Space Station.
J Appl Physiol. 2011 Dec 1. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22134699
NOTE: ISS results. From abstract: "Overall, these data show no change in markers of cardiovascular stability during long-duration spaceflight and only relatively small changes post-flight in seated rest. The current program routine of countermeasures on ISS provided sufficient stimulus to maintain cardiovascular stability under resting conditions during long-duration spaceflight."

2
Games KE, Sefton JM.
Whole-body vibration influences lower extremity circulatory and neurological function.
Scand J Med Sci Sports. 2011 Nov 23. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22107331

3
Santini L, Capria A, Brusca V, Violo A, Smurra F, Scarfo I, Forleo GB, Papavasileiou LP, Borzi M, Romeo F.
An increased endothelial-independent vasodilation is the hallmark of the neurally mediated syncope.
Clin Cardiol. 2011 Nov 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22125099
NOTE: This article may temporarily be obtained online without charge.

4
Okada Y, Galbreath MM, Shibata S, Jarvis SS, VanGundy TB, Meier RL, Vongpatanasin W, Levine BD, Fu Q.
Relationship between sympathetic baroreflex sensitivity and arterial stiffness in elderly men and women.
Hypertension. 2011 Nov 21. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22106403

5
Larina IM, Baevsky RM, Pastushkova LK, Navasiolava NM, Custaud MA, Eshmanova AK, Luchitskaya ES.
Seven-day dry immersion: Interrelationship between the changes in the water-electrolyte balance and cardiovascular responses.
Hum Physiol. 2011 Sep;37(5):602-9.
http://dx.doi.org/10.1134/S0362119711050124
NOTE: This is a translation in English of the Russian original published in Fiziologiya Cheloveka 2011 Sep-Oct;37(5):100-7: http://www.ncbi.nlm.nih.gov/pubmed/22117464

6
Bojados M, Jamon M.
Exposure to hypergravity during specific developmental periods differentially affects metabolism and vestibular reactions in adult C57BL/6j mice.
Eur J Neurosci. 2011 Nov 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22122506

7
Maruyama S, Kemuriyama T, Manabe T, Takahata T, Shoji I, Nishida Y.
Severe hypotension during the decreasing phase of Gz stress.in anesthetized rats wearing an anti-G suit.
Aviat Space Environ Med. 2011 Nov;82(11):1030-6.
http://www.ncbi.nlm.nih.gov/pubmed/22097637

8
Nusbaum DM.
Two-depth transcranial Doppler: A novel approach for non-invasive absolute intracranial pressure measurement.
Aviat Space Environ Med. 2011 Nov;82(11):1080-1.
http://www.ncbi.nlm.nih.gov/pubmed/22097647
NOTE: This article, in the Science and Technology Watch section of the journal, may be obtained online without charge at: http://www.ingentaconnect.com/content/asma/asem/2011/00000082/00000011/a...

9
Zhang ZJ, Tong YQ, Wang JJ, Yang C, Zhou GH, Li YH, Xie PL, Hu JY, Li GC.
Spaceflight alters the gene expression profile of cervical cancer cells.
Chin J Cancer. 2011 Dec;30(12):842-52. Epub 2011 Nov 18.
http://www.ncbi.nlm.nih.gov/pubmed/22098948
NOTE: Shenzhou 4 results. This article may be obtained online without charge.

10
Dayanandan P.
Gravitational biology and space life sciences: Current status and implications for the Indian space programme.
J Biosci. 2011 Dec;36(5):911-9.
http://www.ncbi.nlm.nih.gov/pubmed/22116289
NOTE: This article may be obtained online without charge.

11
Grenon SM, Saary J.
Challenges in aerospace medicine education.
Aviat Space Environ Med. 2011 Nov;82(11):1071-2.
http://www.ncbi.nlm.nih.gov/pubmed/22097645

12
Gao YF, Wang J, Wang HP, Feng B, Dang K, Wang Q, Hinghofer-Szalkay HG.
Skeletal muscle is protected from disuse in hibernating dauria ground squirrels.
Comp Biochem Physiol A Mol Integr Physiol. 2011 Nov 22. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22133905

13
Coker RH, Wolfe RR.
Bedrest and sarcopenia.
Curr Opin Clin Nutr Metab Care. 2012 Jan;15(1):7-11.
http://www.ncbi.nlm.nih.gov/pubmed/22108096

14
Bhatnagar S, Kumar A.
The TWEAK-Fn14 system: Breaking the silence of cytokine-induced skeletal muscle wasting.
Curr Mol Med. 2012 Jan;12(1):3-13.
http://www.ncbi.nlm.nih.gov/pubmed/22082477

15
Juffer P, Jaspers RT, Lips P, Bakker AD, Klein-Nulend J.
Expression of muscle anabolic and metabolic factors in mechanically loaded MLO-Y4 osteocytes.
Am J Physiol Endocrinol Metab. 2011 Nov 22. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22114022

16
Reed SA, Sandesara PB, Senf SM, Judge AR.
Inhibition of FoxO transcriptional activity prevents muscle fiber atrophy during cachexia and induces hypertrophy.
FASEB J. 2011 Nov 18. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22102632

17
Holy X, Collombet JM, Labarthe F, Granger-Veyron N, Begot L.
Effects of seasonal vitamin D deficiency and respiratory acidosis on bone metabolism markers in submarine crewmembers during prolonged patrols.
J Appl Physiol. 2011 Dec 1. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22134698

18
Burr DB.
Why bones bend but don't break.
J Musculoskelet Neuronal Interact. 2011 Dec;11(4):270-85.
http://www.ncbi.nlm.nih.gov/pubmed/22130136
NOTE: This article may be obtained online without charge.

19
Agholme F, Isaksson H, Li X, Ke HZ, Aspenberg P.
Anti-sclerostin antibody and mechanical loading appear to influence metaphyseal bone independently in rats.
Acta Orthop. 2011 Oct;82(5):628-32.
http://www.ncbi.nlm.nih.gov/pubmed/22103277
NOTE: This article may temporarily be obtained online without charge.

20
Li J, Rose E, Frances D, Sun Y, You L.
Effect of oscillating fluid flow stimulation on osteocyte mRNA expression.
J Biomech. 2011 Nov 25. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22119108

21
Anderson JL, Waters MA, Hein MJ, Schubauer-Berigan MK, Pinkerton LE.
Assessment of occupational cosmic radiation exposure of flight attendants using questionnaire data.
Aviat Space Environ Med. 2011 Nov;82(11):1049-54.
http://www.ncbi.nlm.nih.gov/pubmed/22097640

22
Sayenko DG, Artamonov AA, Kozlovskaya IB.
Characteristics of postural corrective responses before and after long-term spaceflights.
Hum Physiol. 2011 Sep;37(5):594-601.
http://dx.doi.org/10.1134/S0362119711050197
NOTE: ISS results. This is a translation in English of the Russian original published in Fiziologiya Cheloveka 2011 Sep-Oct;37(5):91-9: http://www.ncbi.nlm.nih.gov/pubmed/22117463

23
Laurens J, Valko Y, Straumann D.
Experimental parameter estimation of a visuo-vestibular interaction model in humans.
J Vestib Res. 2011 Jan 1;21(5):251-66
http://www.ncbi.nlm.nih.gov/pubmed/22101296

24
Hanes DA.
Mathematical requirements of visual-vestibular integration.
J Math Biol. 2011 Dec 2. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22134859
NOTE: This article may temporarily be obtained online without charge.

25
Fetsch CR, Pouget A, DeAngelis GC, Angelaki DE.
Neural correlates of reliability-based cue weighting during multisensory integration.
Nat Neurosci. 2011 Nov 20. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22101645

26
Johnson MB, Van Emmerik R EA.
Effect of head orientation on postural control during upright stance and forward lean.
Motor Control. 2011 Nov 16. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22104661

27
Keshavarz B, Hecht H.
Axis rotation and visually induced motion sickness: The role of combined roll, pitch, and yaw motion.
Aviat Space Environ Med. 2011 Nov;82(11):1023-9.
http://www.ncbi.nlm.nih.gov/pubmed/22097636

28
Kawashima Y, Geleoc GS, Kurima K, Labay V, Lelli A, Asai Y, Makishima T, Wu DK, Della Santina CC, Holt JR, Griffith AJ.
Mechanotransduction in mouse inner ear hair cells requires transmembrane channel-like genes.
J Clin Invest. 2011 Dec 1;121(12):4796-809. Epub 2011 Nov 21.
http://www.ncbi.nlm.nih.gov/pubmed/22105175
NOTE: This article may be obtained online without charge. There is a comment on the article at: http://www.ncbi.nlm.nih.gov/pubmed/22105165

29
Gorgiladze GI.
Regenerative capacity of the eye of Helix lucorum in a 163-day orbital flight aboard the International Space Station.
Dokl Biol Sci. 2011 Oct;440(1):316-9. Epub 2011 Dec 2.
http://www.ncbi.nlm.nih.gov/pubmed/22134821
NOTE: ISS results. This paper is a translation in English of the Russian original published in Doklady Akademii Nauk 2011;440(4):553-6.

30
Borau C, Kamm RD, Garcia-Aznar JM.
Mechano-sensing and cell migration: A 3D model approach.
Phys Biol. 2011 Dec;8(6):066008. Epub 2011 Nov 25.
http://www.ncbi.nlm.nih.gov/pubmed/22120116

31
Driquez B, Bouclet A, Farge E.
Mechanotransduction in mechanically coupled pulsating cells: Transition to collective constriction and mesoderm invagination simulation.
Phys Biol. 2011 Dec;8(6):066007. Epub 2011 Nov 25.
http://www.ncbi.nlm.nih.gov/pubmed/22120059

32
Shoham N, Gefen A.
Mechanotransduction in adipocytes.
J Biomech. 2011 Nov 21. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22112919

33
Vernerey FJ, Farsad M.
A constrained mixture approach to mechano-sensing and force generation in contractile cells.
J Mech Behav Biomed Mater. 2011 Nov;4(8):1683-99. Epub 2011 May 17.
http://www.ncbi.nlm.nih.gov/pubmed/22098869

34
Zhang JZ, Gao WY, Gao Y, Liu DL, Huang LQ.
Analysis of influences of spaceflight on chemical constituents in licorice by HPLC-ESI-MS/MS.
Acta Physiol Plantarum. 2011 Nov;33(6):2511-20.
http://dx.doi.org/10.1007/s11738-011-0796-7
NOTE: Results from plants grown from seeds flown on a Chinese space flight.

35
Sakai T, Mochizuki S, Haga K, Uehara Y, Suzuki A, Harada A, Wada T, Ishiguro S, Okada K.
The WAVY GROWTH 3 E3 ligase family controls the gravitropic response in Arabidopsis roots.
Plant J. 2011 Nov 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22122664

// end //

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