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NASA Spaceline Current Awareness 29 July 2011 (Recent Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, July 29, 2011

image

Papers deriving from NASA support:

1
Morgan JL, Gordon G, Arrua RC, Skulan JL, Anbar AD.
High precision measurements of variations in calcium isotope rations in urine by multiple collector inductively coupled plasma mass spectrometry (MC-ICP-MS).
Anal Chem. 2011 Jul 8. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21740001
(PI: A.D. Anbar)

2
Serra-Hsu F, Cheng J, Lynch T, Qin YX.
Evaluation of a pulsed phase-locked loop system for noninvasive tracking of bone deformation under loading with finite element and strain analysis.
Physiol Meas. 2011 Aug;32(8):1301-13. Epub 2011 Jul 15.
http://www.ncbi.nlm.nih.gov/pubmed/21765205
(PI: Y.X. Qin)

3
Teresa Ortega M, Xie L, Mora S, Chapes SK.
Evaluation of macrophage plasticity in brown and white adipose tissue.
Cell Immunol. 2011 Jun 23. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21757190
(PI: S.K. Chapes)

4
Sanzari JK, Wilson JM, Wagner EB, Kennedy AR.
The combined effects of reduced weightbearing and ionizing radiation on splenic lymphocyte population and function.
Int J Radiat Biol. 2011 Jul 19. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21770700
(PI: A.R. Kennedy/Center of Acute Radiation Research)

5
Singh SK, Wang M, Staudt C, Iliakis G.
Post-irradiation chemical processing of DNA damage generates double-strand breaks in cells already engaged in repair.
Nucleic Acids Res. 2011 Jul 10. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21745815
NOTE: This article may be obtained online without charge.

6
Delgado O, Kaisani AA, Spinola M, Xie XJ, Batten KG, Minna JD, Wright WE, Shay JW.
Multipotent capacity of immortalized human bronchial epithelial cells.
PLoS One. 2011;6(7):e22023. Epub 2011 Jul 7.
http://www.ncbi.nlm.nih.gov/pubmed/21760947
(PI: J.D. Minna/X.J. Xie/W.E. Wright/J.W.Shay/NSCOR)
NOTE: This article may be obtained online without charge.

7
Acharya MM, Christie LA, Lan ML, Giedzinski E, Fike JR, Rosi S, Limoli CL.
Human neural stem cell transplantation ameliorates radiation-induced cognitive dysfunction.
Cancer Res. 2011 Jul 15;71(14):4834-45. Epub 2011 Jul 14.
http://www.ncbi.nlm.nih.gov/pubmed/21757460
(PI: C.L. Limoli)

8
Chen M, Xie Y, Story M.
An exponential-gamma convolution model for background correction of Illumina BeadArray data.
Commun Stat Theory Methods. 2011 Sep 1;40(17):3055-69.
http://www.ncbi.nlm.nih.gov/pubmed/21769162
(PIs: J.D. Minna/M. Story/NSCOR; R.L. Ullrich/Y. Xie/M. Story/NSCOR)

9
McArthur KL, Zakir M, Haque A, Dickman JD.
Spatial and temporal characteristics of vestibular convergence.
Neuroscience. 2011 Jul 1. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21756981
(PI: J.D. Dickman)

10
McLamore ES, Porterfield DM.
Non-invasive tools for measuring metabolism and biophysical analyte transport: Self-referencing physiological sensing.
Chem Soc Rev. 2011 Jul 15. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21761069
(PI: D.M. Porterfield)

11
Jules K, Istasse E, Stenuit H, Murakami K, Yoshizaki I, Johnson-Green P.
Summary of recent research accomplishment onboard the International Space Station--Within the United States Orbital Segment.
Microgravity Sci Technol. 2011 Jun;23(3):311-43.
http://dx.doi.org/10.1007/s12217-010-9253-2
NOTE: Article describes research conducted during ISS increments 16 and 17 (October 2007 to October 2008).

12
Hammond T, Allen P.
The Bonn criteria: Minimal experimental parameter reporting for clinostat and random positioning machine experiments with cells and tissues.
Microgravity Sci Technol. 2011 Feb;23(2):271-5.
http://dx.doi.org/10.1007/s12217-010-9226-5
(PI: T. Hammond)

Other papers of interest:

1
Charles D.
Science on the shuttle. NASA's busload of science.
Science. 2011 Jul 1;333(6038):28-9.
http://www.ncbi.nlm.nih.gov/pubmed/21719655
NOTE: This article and a companion article on pages 30-33, "The highs and lows of shuttle science," attempt to summarize the scientfic accomplishments resulting from the shuttle.

2
Yamamoto K, Ando J.
New molecular mechanisms for cardiovascular disease: Blood flow sensing mechanism in vascular endothelial cells.
J Pharmacol Sci. 2011 Jul 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21757846
NOTE: This article may be obtained online without charge.

3
Sinusas AJ, Thomas JD, Mills G.
The future of molecular imaging.
JACC Cardiovasc Imaging. 2011 Jul;4(7):799-806.
http://www.ncbi.nlm.nih.gov/pubmed/21757172
NOTE: The authors argue the pros and cons of molecular imaging in cardiovascular medicine. PI J.D. Thomas and G. Mills state: "Despite all its cellular and molecular intricacies, the assessment of cardiovascular health involves few concepts outside the realm of a plumber or auto mechanic: the heart should be anatomically accurate in its construction; it should accept blood at low pressure and pump it out at high pressure through valves that neither leak nor obstruct; and it requires a steady delivery of fuel at rest and, more importantly, with exercise. In all of these arenas, contemporary cardiovascular imaging does an outstanding job."

4
Chen Y, Montcalm-Smith E, Schlaerth C, Auker CR, McCarron RM.
Acclimation to decompression: Stress and cytokine gene expressioin in rat lungs.
J Appl Physiol. 2011 Jul 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21757575

5
Kim JH, Coca A, Williams WJ, Roberge RJ.
Subjective perceptions and ergonomics evaluation of a liquid cooled garment worn under protective ensemble during an intermittent treadmill exercise.
Ergonomics. 2011 Jul;54(7):626-35.
http://www.ncbi.nlm.nih.gov/pubmed/21770750

6
Ringholm S, Bienso RS, Kiilerich K, Guadalupe-Grau A, Aachmann-Andersen NJ, Saltin B, Plomgaard P, Lundby C, Wojtaszewski JF, Calbet JA, Pilegaard H.
Bed rest reduces metabolic protein content and abolishes exercise-induced mRNA responses in human skeletal muscle.
Am J Physiol Endocrinol Metab. 2011 Jul 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21750272
NOTE: Bed rest study.

7
Lueders TN, Zou K, Huntsman HD, Meador B, Mahmassani Z, Abel M, Valero MC, Huey KA, Boppart MD.
The {alpha}7{beta}1 integrin accelerates fiber hypertrophy and myogenesis following a single bout of eccentric exercise.
Am J Physiol Cell Physiol. 2011 Jul 13. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21753185

8
Barnes MJ, Perry BG, Muendel T, Cochrane DJ.
The effects of vibration therapy on muscle force loss following eccentrically induced muscle damage.
Eur J Appl Physiol. 2011 Jul 13. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21750975

9
Sharir A, Zelzer E.
Tendon homeostasis: The right pull.
Curr Biol. 2011 Jun 21;21(12):R472-4.
http://www.ncbi.nlm.nih.gov/pubmed/21683902
NOTE: This is a comment on an article about converting mechanical force into biochemical signals in tendon: http://www.ncbi.nlm.nih.gov/pubmed/21600772

10
Brooks NE, Myburgh KH, Storey KB.
Myostatin levels in skeletal muscle of hibernating ground squirrels.
J Exp Biol. 2011 Aug 1;214(Pt 15):2522-7.
http://www.ncbi.nlm.nih.gov/pubmed/21753045

11
Larrue A, Rattner A, Peter ZA, Olivier C, Laroche N, Vico L, Peyrin F.
Synchrotron radiation micro-CT at the micrometer scale for the analysis of the three-dimensional morphology of microcracks in human trabecular bone.
PLoS One. 2011;6(7):e21297. Epub 2011 Jul 7.
http://www.ncbi.nlm.nih.gov/pubmed/21750707
NOTE: This article may be obtained online without charge.

12
Ban Y, Wu YY, Yu T, Geng N, Wang YY, Liu XG, Gong P.
Response of osteoblasts to low fluid shear stress is time dependent.
Tissue Cell. 2011 Jul 20. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21764096

13
Abdallah BM, Kassem M.
New factors controlling the balance between osteoblastogenesis and adipogenesis.
Bone. 2011 Jul 1. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21745614

14
van der Jagt OP, van der Linden JC, Waarsing JH, Verhaar JA, Weinans H.
Low-magnitude whole body vibration does not affect bone mass but does affect weight in ovariectomized rats.
J Bone Miner Metab. 2011 Jul 20. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21773704

15
Wang Y, Huang P, Tang PF, Chan KM, Li G.
Alendronate (ALN) combined with osteoprotegerin (OPG) significantly improves mechanical properties of long bone than the single use of ALN or OPG in the ovariectomized rats.
J Orthop Surg Res. 2011 Jul 13;6:34. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21752290
NOTE: This article may be obtained online without charge.

16
Xie H, Xie PL, Luo XH, Wu XP, Zhou HD, Tang SY, Liao EY.
Omentin-1 exerts bone-sparing effect in ovariectomized mice.
Osteoporos Int. 2011 Jul 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21755404

17
Xie H, Xie PL, Wu XP, Chen SM, Zhou HD, Yuan LQ, Sheng ZF, Tang SY, Luo XH, Liao EY.
Omentin-1 attenuates arterial calcification and bone loss in osteoprotegerin-deficient mice by inhibition of RANKL expression.
Cardiovasc Res. 2011 Jul 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21750093

18
Yamaguchi M, Weitzmann MN.
Quercetin, a potent suppressor of NF-B and Smad activation in osteoblasts.
Int J Mol Med. 2011 Oct;28(4):521-5. Epub 2011 Jul 14.
http://www.ncbi.nlm.nih.gov/pubmed/21769418

19
Yasuda T, Oda S, Yasuda H, Hibi Y, Anzai K, Mitani H.
Neurocytotoxic effects of iron-ions on the developing brain measured in vivo using medaka (Oryzias latipes), a vertebrate model.
Int J Radiat Biol. 2011 Jul 19. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21770703
NOTE: This article may be obtained online without charge.

20
Wang C, Smith RW, Duhig J, Prestwich WV, Byun SH, McNeill FE, Seymour CB, Mothersill CE.
Neutrons do not produce a bystander effect in zebrafish irradiated in vivo.
Int J Radiat Biol. 2011 Jul 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21756060

21
Liljequist D, Liamsuwan T, Nikjoo H.
Elastic scattering cross section models used for Monte Carlo simulation of electron tracks in media of biological and medical interest.
Int J Radiat Biol. 2011 Jul 15. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21756208

22
Yates ES, Balling P, Petersen JB, Christensen MN, Skyt PS, Bassler N, Kaiser FJ, Muren LP.
Characterization of the optical properties and stability of Presage(TM) following irradiation with photons and carbon ions.
Acta Oncol. 2011 Aug;50(6):829-34.
http://www.ncbi.nlm.nih.gov/pubmed/21767181

23
Abe C, Iwata C, Shiina T, Shimizu Y, Morita H.
Effect of daily linear acceleration training on the hypergravity-induced vomiting response in house musk shrew (Suncus murinus).
Neurosci Lett. 2011 Jun 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21741451

24
Harris LR, Jenkin M, Dyde RT, Jenkin H.
Enhancing visual cues to orientation: Suggestions for space travelers and the elderly.
Prog Brain Res. 2011;191:133-42.
http://www.ncbi.nlm.nih.gov/pubmed/21741549

25
Ichijo H.
Persistent direction-changing geotropic positional nystagmus.
Eur Arch Otorhinolaryngol. 2011 Jul 12. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21748654

26
Smith AT, Wall MB, Thilo KV.
Vestibular inputs to human motion-sensitive visual cortex.
Cereb Cortex. 2011 Jul 9. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21743097

27
Colucci V, Cataldi A.
Human bipedism and microgravity.
Gazz Med Ital. 2011 Apr;170(2):135-9.
http://www.minervamedica.it/en/journals/gazzetta-medica-italiana/article...

28
Pilcher JJ, Vander Wood MA, O'Connell KL.
The effects of extended work under sleep deprivation conditions on team-based performance.
Ergonomics. 2011 Jul;54(7):587-96.
http://www.ncbi.nlm.nih.gov/pubmed/21770747

29
Summa KC, Turek FW.
The genetics of sleep: Insight from rodent models.
Sleep Med Clin. 2011 Jun;6(2):141-54.
http://www.ncbi.nlm.nih.gov/pubmed/21765816
NOTE: This article is in an issue on the topic of "Genetics of Sleep and its Disorders." The introductory material may be obtained online without charge. Table of Contents: http://www.sleep.theclinics.com/issues?issue_key=S1556-407X(11)X0003-6

30
Silva CF, Duarte FS, Lima TC, de Oliveira CL.
Effects of social isolation and enriched environment on behavior of adult Swiss mice do not require hippocampal neurogenesis.
Behav Brain Res. 2011 Nov 20;225(1):85-90. Epub 2011 Jul 8.
http://www.ncbi.nlm.nih.gov/pubmed/21767574

31
Wu C, Guo X, Wang F, Li X, Tian XC, Li L, Wu Z, Zhang S.
Simulated microgravity compromises mouse oocyte maturation by disrupting meiotic spindle organization and inducing cytoplasmic blebbing.
PLoS One. 2011;6(7):e22214. Epub 2011 Jul 13.
http://www.ncbi.nlm.nih.gov/pubmed/21765954
NOTE: This article may be obtained online without charge.

32
Eyckmans J, Boudou T, Yu X, Chen CS.
A Hitchhiker's Guide to mechanobiology.
Dev Cell. 2011 Jul 19;21(1):35-47.
http://www.ncbi.nlm.nih.gov/pubmed/21763607
NOTE: This overview of this topic appears in the 10th anniversary issue of this journal. The authors point out that "the development of mechanobiology as a field appears to be closely connected to the advent of enabling technologies." The article may be obtained online without charge.

33
Malcolm HR, Heo YY, Elmore DE, Maurer JA.
Defining the role of the tension sensor in the mechanosensitive channel of small conductance.
Biophys J. 2011 Jul 20;101(2):345-52.
http://www.ncbi.nlm.nih.gov/pubmed/21767486

34
Zebda N, Dubrovskyi O, Birukov KG.
Focal adhesion kinase regulation of mechanotransduction and its impact on endothelial cell functions.
Microvasc Res. 2011 Jun 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21741394

35
Wenger KH, El-Awady AR, Messer RL, Sharawy MM, White G, Lapp CA.
Pneumatic pressure bioreactor for cyclic hydrostatic stress application. Mechanobiology effects on periodontal ligament cells.
J Appl Physiol. 2011 Jul 14. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21757574

36
Mazzolai B, Mondini A, Corradi P, Laschi C, Mattoli V, Sinibaldi E, Dario P.
A miniaturized mechatronic system inspired by plant roots for soil exploration.
IEEE/ASME Trans Mechatron. 2011 Apr;16(2):201-12.
http://dx.doi.org/10.1109/TMECH.2009.2038997

37
Schmidt W.
Gravireception in Phycomyces blakesleeanus and Arabidopsis thaliana: Hysteretic behavior of primary reactions.
Microgravity Sci Technol. 2011 Jun;23(3):355-64.
http://dx.doi.org/10.1007/s12217-010-9255-0
NOTE: Parabolic flight results.

38
Callens C, Ventura-Traveset J, de Lophem TL, Lopez de Echazarreta C, Pletser V, van Loon JJ.
ESA parabolic flights, drop tower and centrifuge opportunities for university students.
Microgravity Sci Technol. 2011 Feb;23(2):181-9.
http://dx.doi.org/10.1007/s12217-010-9181-1
NOTE: This article may be obtained online without charge.

39
Hofmeister PG, Blum J.
Parabolic flights @ home: An unmanned air vehicle for short-duration low-gravity experiments.
Microgravity Sci Technol. 2011 Feb;23(2):191-7.
http://dx.doi.org/10.1007/s12217-010-9249-y

40
Pletser V, Foing B.
European contribution to human aspect investigations for future planetary habitat definition studies: Field tests at MDRS on crew time utilisation and habitat interfaces.
Microgravity Sci Technol. 2011 Feb;23(2):199-214.
http://dx.doi.org/10.1007/s12217-010-9251-4

41
Brykov V.
Clinorotation affects the ultrastructure of pea root mitochondria.
Microgravity Sci Technol. 2011 Feb;23(2):215-9.
http://dx.doi.org/10.1007/s12217-010-9201-1

42
Kondrachuk AV, Starkov VN.
Modeling the kinetics of root gravireaction.
Microgravity Sci Technol. 2011 Feb;23(2):221-5.
http://dx.doi.org/10.1007/s12217-010-9207-8

43
Rakleviien D, Losinska R, vegdien D.
Clinorotation effect on response of cress leaves to red and far-red light.
Microgravity Sci Technol. 2011 Feb;23(2):227-33.
http://dx.doi.org/10.1007/s12217-010-9208-7

44
vegdien D, Koryznien D, Rakleviien D.
Comparison study of gravity-dependent displacement of amyloplasts in statocytes of cress roots and hypocotyls.
Microgravity Sci Technol. 2011 Feb;23(2):235-41.
http://dx.doi.org/10.1007/s12217-010-9190-0

45
Horn ER, Boeser S, Franz M, Gabriel M, Hiesgen N, Kuebler U, Porciani M, Schwarzwaelder A, Zolesi V.
Development of the flight hardware for the experiment XENOPUS on the Kubik BIO4-Mission.
Microgravity Sci Technol. 2011 Feb;23(2):243-8.
http://dx.doi.org/10.1007/s12217-010-9182-0

46
Moes MJ, Gielen JC, Bleichrodt RJ, van Loon JJ, Christianen PC, Boonstra J.
Simulation of microgravity by magnetic levitation and random positioning: Effect on human A431 cell morphology.
Microgravity Sci Technol. 2011 Feb;23(2):249-61.
http://dx.doi.org/10.1007/s12217-010-9185-x
NOTE: This article may be obtained online without charge.

47
Li X, Anken RH, Wang G, Hilbig R, Liu Y.
Effects of wall vessel rotation on the growth of larval zebrafish inner ear otoliths.
Microgravity Sci Technol. 2011 Jan;23(1):13-8.
http://dx.doi.org/10.1007/s12217-010-9215-8
NOTE: This article may be obtained online without charge.

48
Dai Z, Tan Y, Yang F, Qu L, Zhang H, Wan Y, Li Y.
Altered actin dynamics and functions of osteoblast-Like cells in parabolic flight may involve ERK1/2.
Microgravity Sci Technol. 2011 Jan;23(1):19-27.
http://dx.doi.org/10.1007/s12217-010-9216-7
NOTE: Parabolic flight results. This article may be obtained online without charge.

49
Jagtap SS, Awhad RB, Santosh B, Vidyasagar PB.
Effects of clinorotation on growth and chlorophyll content of rice seeds.
Microgravity Sci Technol. 2011 Jan;23(1):41-8.
http://dx.doi.org/10.1007/s12217-010-9222-9
NOTE: This article may be obtained online without charge.

50
Horn A, Ullrich O, Huber K, Hemmersbach R.
PMT (photomultiplier) clinostat.
Microgravity Sci Technol. 2011 Jan;23(1):67-71.
http://dx.doi.org/10.1007/s12217-010-9234-5
NOTE: This article may be obtained online without charge.

51
Dreyer M.
The Drop Tower Bremen.
Microgravity Sci Technol. 2010 Oct;22(4):461.
http://dx.doi.org/10.1007/s12217-010-9242-5
NOTE: This editorial introduces a topical issue on drop tower related research, marking the 20th anniversary of the drop tower Bremen. The articles in the issue report physical sciences research.

// end //

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