NASA Spaceline Current Awareness 14 September 2012 (Recent Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, September 14, 2012


Papers deriving from NASA support:

Stabley JN, Dominguez II JM, Dominguez CE, Mora Solis FR, Ahlgren J, Behnke BJ, Muller-Delp JM, Delp MD.
Spaceflight reduces vasoconstrictor responsiveness of skeletal muscle resistance arteries in mice.
J Appl Physiol. 2012 Sep 13. [Epub ahead of print]
(PI: M.D. Delp)
NOTE: STS-131 results.

Park Y, Prisby RD, Behnke BJ, Dominguez JM 2nd, Lesniewski LA, Donato AJ, Muller-Delp JM, Delp MD.
Effects of aging, TNF- and exercise training on angiotensin II-induced vasoconstriction of rat skeletal muscle arterioles.
J Appl Physiol. 2012 Aug 23. [Epub ahead of print]
(PI: M.D. Delp)

Li Y, Lai N, Kirwan JP, Saidel GM.
Computational model of cellular metabolic dynamics in skeletal muscle fibers during moderate intensity exercise.
Cell Mol Bioeng. 2012 Mar;5(1):92-112.
(PI: G.M. Saidel/M. Cabrera)

Datta K, Suman S, Kallakury BV, Fornace AJ Jr.
Exposure to heavy ion radiation induces persistent oxidative stress in mouse intestine.
PLoS One. 2012;7(8):e42224. Epub 2012 Aug 24.
(PIs: A.J. Fornace; A.J. Fornace/K. Datta/NSCOR)
NOTE: This article may be obtained online without charge.

Mehrotra S, Pecaut MJ, Gridley DS.
Analysis of minocycline as a countermeasure against acute radiation syndrome.
In Vivo. 2012 Sep-Oct;26(5):743-58.

Hsu FM, Zhang S, Chen BP.
Role of DNA-dependent protein kinase catalytic subunit in cancer development and treatment.
Transl Cancer Res. 2012 Jun 1;1(1):22-34. Epub 2012 May 22.
(PI: B.P. Chen)
NOTE: This article may be obtained online without charge via PubMed Central and at the publisher's site:
PI C.Y. Li comments on this article; the comment may also be obtained online without charge:

Almog N, Ma L, Schwager C, Brinkmann BG, Beheshti A, Vajkoczy P, Folkman J, Hlatky L, Abdollahi A.
Consensus micro RNAs governing the switch of dormant tumors to the fast-growing angiogenic phenotype.
PLoS One. 2012;7(8):e44001. Epub 2012 Aug 31.
(PI: L. Hlatky/J. Folkman/A. Abdollahi/NSCOR)
NOTE: This article may be obtained online without charge.

Clement G, Skinner A, Richard G, Lathan C.
Geometric illusions in astronauts during long-duration spaceflight.
Neuroreport. 2012 Oct 24;23(15):894-9.
(PI: C. Lathan)
NOTE: ISS results.

Contento AL, Bassham DC.
Structure and function of endosomes in plant cells.
J Cell Sci. 2012 Aug 30. [Epub ahead of print]
(PI: D.C. Bassham)

Moreno AA, Mukhtar MS, Blanco F, Boatwright JL, Moreno I, Jordan MR, Chen Y, Brandizzi F, Dong X, Orellana A, Pajerowska-Mukhtar KM.
IRE1/bZIP60-mediated unfolded protein response plays distinct roles in plant immunity and abiotic stress responses.
PLoS One. 2012;7(2):e31944. Epub 2012 Feb 16.
(PI: F. Brandizzi)
NOTE: This article may be obtained online without charge.

Teasley Hamorsky K, Ensor CM, Dikici E, Pasini P, Bachas L, Daunert S.
Bioluminescence inhibition assay for the detection of hydroxylated polychlorinated biphenyls.
Anal Chem. 2012 Aug 21. [Epub ahead of print]

Other papers of interest:

Schneider S, Abeln V, Popova J, Fomina E, Jacubowski A, Meeusen R, Strueder HK.
The influence of exercise on prefrontal cortex activity and cognitive performance during a simulated space flight to Mars (MARS500).
Behav Brain Res. 2012 Aug 24. [Epub ahead of print]
NOTE: MARS500 isolation study.

Arinell K, Froebert O, Blanc S, Larsson A, Christensen K.
Downregulation of platelet activation markers during long-term immobilization.
Platelets. 2012 Aug 29. [Epub ahead of print]
NOTE: WISE-2005 bed rest study.

Law J, Vanderploeg J.
An emergency medical planning guide for commercial spaceflight events.
Aviat Space Environ Med. 2012 Sep;83(9):890-5.

Ichinose M, Nishiyasu T.
Arterial baroreflex control of muscle sympathetic nerve activity under orthostatic stress in humans.
Front Physiol. 2012;3:314. Epub 2012 Aug 7.
NOTE: This article may be obtained online without charge.

Liu Y, Zhang LF, Zhang KL, Lu HB.
Role of carotid baroreflex and sympathetic responses in the push-pull effect: A simulation study.
Aviat Space Environ Med. 2012 Sep;83(9):841-9.

Elbey MA, Atilgan Z, Cil H, Kaya H, Ertas F, Aydin M, Ozaydogdu N.
Carotid artery stiffness in patients with neurally mediated syncope.
J Ultrasound Med. 2012 Sep 1;31(9):1431-5.

Saei AA, Barzegari A.
The microbiome: The forgotten organ of the astronaut's body - probiotics beyond terrestrial limits.
Future Microbiol. 2012 Sep;7(9):1037-46.
NOTE: Authors' affiliation: Research Center for Pharmaceutical Nanotechnology, Astrobiology & Space Medicine Laboratory, Tabriz University of Medical Sciences, Tabriz, Iran.

Chang D, Guo YH, Liu CT..
[Research advance in effects of weightlessness or simulated weightlessness on tumor cells]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Aug;34(4):422-5. Chinese.
NOTE: Tranlated title of journal is Acta Academiae Medicinae Sinicae. This article may be obtained online without charge.

Pei SJ, Zhu ML, Yi Y, Zhou JL, Xu BX, Wang P.
[Changes of anti-Streptococcus pneumoniae status in rats with simulated weightlessness]
Zhonghua Jie He He Hu Xi Za Zhi. 2012 Jul;35(7):515-9. Chinese.
NOTE: Tranlated title of journal is Chinese Journal of Tuberculosis and Respiratory Diseases.

Mallinson JE, Murton AJ.
Mechanisms responsible for disuse muscle atrophy: Potential role of protein provision and exercise as countermeasures.
Nutrition. 2012 Aug 27. [Epub ahead of print]

Rudolf R, Bogomolovas J, Strack S, Choi KR, Khan MM, Wagner A, Brohm K, Hanashima A, Gasch A, Labeit D, Labeit S.
Regulation of nicotinic acetylcholine receptor turnover by MuRF1 connects muscle activity to endo/lysosomal and atrophy pathways.
Age (Dordr). 2012 Sep 6. [Epub ahead of print]
NOTE: This article may be obtained online without charge.

Elmantaser M, McMillan M, Smith K, Khanna S, Chantler D, Panarelli M, Ahmed SF.
A comparison of the effect of two types of vibration exercise on the endocrine and musculoskeletal system.
J Musculoskelet Neuronal Interact. 2012 Sep;12(3):144-54.
NOTE: This article may be obtained online without charge.

Andersson T, Eliasson P, Hammerman M, Sandberg O, Aspenberg P.
Low level mechanical stimulation is sufficient to improve tendon healing in rats.
J Appl Physiol. 2012 Aug 30. [Epub ahead of print]

Deng B, Wehling-Henricks M, Villalta SA, Wang Y, Tidball JG.
IL-10 triggers changes in macrophage phenotype that promote muscle growth and regeneration.
J Immunol. 2012 Aug 29. [Epub ahead of print]

O'Brien CA, Nakashima T, Takayanagi H.
Osteocyte control of osteoclastogenesis.
Bone. 2012 Aug 23. [Epub ahead of print]

Prodanov L, van Loon JJ, te Riet J, Jansen JA, Walboomers XF.
Nanostructured substrate conformation can decrease osteoblast-like cell dysfunction in simulated microgravity conditions.
J Tissue Eng Regen Med. 2012 Sep 3. [Epub ahead of print]

Evans RK, Negus CH, Centi AJ, Spiering BA, Kraemer WJ, Nindl BC.
Peripheral QCT sector analysis reveals early exercise-induced increases in tibial bone mineral density.
J Musculoskelet Neuronal Interact. 2012 Sep;12(3):155-64.
NOTE: This article may be obtained online without charge.

Whitney NP, Lamb AC, Louw TM, Subramanian A.
Integrin-mediated mechanotransduction pathway of low-intensity continuous ultrasound in human chondrocytes.
Ultrasound Med Biol. 2012 Oct;38(10):1734-43. Epub 2012 Aug 21.

Schardt D, Kavatsyuk O, Kraemer M, Durante M.
Light flashes in cancer patients treated with heavy ions.
Brain Stimul. 2012 Aug 27. [Epub ahead of print]

Genet SC, Maeda J, Fujisawa H, Yurkon CR, Fujii Y, Romero AM, Genik PC, Fujimori A, Kitamura H, Kato TA.
Comparison of cellular lethality in DNA repair-proficient or -deficient cell lines resulting from exposure to 70 MeV/n protons or 290 MeV/n carbon ions.
Oncol Rep. 2012 Nov;28(5):1591-6. Epub 2012 Aug 22.

Schmid TE, Greubel C, Hable V, Zlobinskaya O, Michalski D, Girst S, Siebenwirth C, Schmid E, Molls M, Multhoff G, Dollinger G.
Low LET protons focused to submicrometer shows enhanced radiobiological effectiveness.
Phys Med Biol. 2012 Sep 7;57(19):5889-907. [Epub ahead of print]
NOTE: This article may be obtained online without charge.

Javvadi P, Makino H, Das AK, Lin YF, Chen DJ, Chen BP, Nirodi CS.
Threonine 2609 phosphorylation of the DNA-dependent Protein Kinase is a critical prerequisite for epidermal growth factor receptor mediated radiation resistance.
Mol Cancer Res. 2012 Aug 23. [Epub ahead of print]

Wang B, Tanaka K, Ninomiya Y, Maruyama K, Vares G, Eguchi-Kasai K, Nenoi M.
Relieved residual damage in the hematopoietic system of mice rescued by radiation-induced adaptive response (Yonezawa Effect).
J Radiat Res. 2012 Aug 24. [Epub ahead of print]

Iliakis G, Mladenov E, Wang Y, Wang HY.
Analysis of inhibition of DNA replication in irradiated cells using the SV40 based in vitro assay of DNA replication.
Methods Mol Biol. 2012;920:591-602.

Iliakis G, Mladenov E, Cheong N.
In vitro rejoining of double strand breaks in genomic DNA.
Methods Mol Biol. 2012;920:471-84.

Lim K, Merfeld DM.
Signal detection theory and vestibular perception: II. Fitting perceptual thresholds as a function of frequency.
Exp Brain Res. 2012 Aug 26. [Epub ahead of print]

Crane BT.
Roll aftereffects: Influence of tilt and inter-stimulus interval.
Exp Brain Res. 2012 Sep 4. [Epub ahead of print]

Gascuel JD, Payno H, Schmerber S, Martin O.
Immersive virtual environment for visuo-vestibular therapy: Preliminary results.
Stud Health Technol Inform. 2012;181:187-91.

Moy JD, Miller DJ, Catanzaro MF, Boyle BM, Ogburn SW, Cotter LA, Yates BJ, McCall AA.
Responses of neurons in the caudal medullary lateral tegmental field to visceral inputs and vestibular stimulation in vertical planes.
Am J Physiol Regul Integr Comp Physiol. 2012 Sep 5. [Epub ahead of print]

Adamson MM, Bayley PJ, Scanlon BK, Farrell ME, Hernandez B, Weiner MW, Yesavage JA, Taylor JL.
Pilot expertise and hippocampal size: Associations with longitudinal flight simulator performance.
Aviat Space Environ Med. 2012 Sep;83(9):850-7.

Liu L, Lv JP, Gao YH.
Selection of high organic chromium yielding yeast strain after space piggyback experiment and its characteristic.
Afr J Microbiol Res. 2012 Jan 9;6(1):127-36.
NOTE: Results of samples carried on a Chinese satellite. This article may be obtained online without charge.

Martinac B.
Mechanosensitive ion channels: An evolutionary and scientific tour de force in mechanobiology.
Channels (Austin). 2012 Jul 1;6(4). [Epub ahead of print]
NOTE: This article introduces a special issue on mechanosensitive ion channels (several of the articles were in previous lists):
This article may be obtained online without charge.

Zhang H, Labouesse M.
Signalling through mechanical inputs - a coordinated process.
J Cell Sci. 2012 Jul 1;125(Pt 13):3039-49.
NOTE: This paper is one of six papers in a Minifocus on Mechanostransduction in this issue:
Two of the other papers appeared in previous lists.

Shekhar S, Cambi A, Figdor CG, Subramaniam V, Kanger JS.
A method for spatially resolved local intracellular mechanochemical sensing and organelle manipulation.
Biophys J. 2012 Aug 8;103(3):395-404.

Gauthier NC, Masters TA, Sheetz MP.
Mechanical feedback between membrane tension and dynamics.
Trends Cell Biol. 2012 Aug 23. [Epub ahead of print]

Young YN, Downs M, Jacobs CR.
Dynamics of the primary cilium in shear flow.
Biophys J. 2012 Aug 22;103(4):629-39.

Dassot M, Fournier M, Ningre F, Constant T.
Effect of tree size and competition on tension wood production over time in beech plantations and assessing relative gravitropic response with a biomechanical model.
Am J Bot. 2012 Sep;99(9):1427-35. Epub 2012 Aug 24.

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