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NASA Spaceline Current Awareness 15 April 2011 (Recent Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, April 15, 2011

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Papers deriving from NASA support:

1
Du B, Daniels VR, Vaksman Z, Boyd JL, Crady C, Putcha L.
Evaluation of physical and chemical changes in pharmaceuticals flown on space missions.
AAPS J. 2011 Apr 9. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21479701
(PI: L. Putcha)
NOTE: ISS results. This article may temporarily be obtained online without charge. There was a press release for this paper: http://www.springer.com/about+springer/media/springer+select?SGWID=0-110...

2
Darquenne C, van Ertbruggen C, Prisk GK.
Convective flow dominates aerosol delivery to the lung segments.
J Appl Physiol. 2011 Apr 7. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21474695
(PI: G.K. Prisk)
NOTE: The researchers used previously obtained parabolic flight data in this modelling/simulation study.

3
Buonanno M, de Toledo SM, Pain D, Azzam EI.
Long-term consequences of radiation-induced bystander effects depend on radiation quality and dose and correlate with oxidative stress.
Radiat Res. 2011 Apr;175(4):405-15. Epub 2011 Feb 14.
http://www.ncbi.nlm.nih.gov/pubmed/21319986
(PI: E.I. Azzam)

4
Ni H, Balint K, Zhou Y, Gridley DS, Maks C, Kennedy AR, Weissman D.
Effect of solar particle event radiation on gastrointestinal tract bacterial translocation and immune activation.
Radiat Res. 2011 Apr;175(4):485-92. Epub 2011 Feb 4.
http://www.ncbi.nlm.nih.gov/pubmed/21294608
(PI: A.R. Kennedy)
NOTE: A figure from this paper appears on the cover of the issue.

5
Fabre KM, Ramaiah L, Dregalla RC, Desaintes C, Weil MM, Bailey SM, Ullrich RL.
Murine Prkdc polymorphisms impact DNA-PKcs function.
Radiat Res. 2011 Apr;175(4):493-500. Epub 2011 Jan 25.
http://www.ncbi.nlm.nih.gov/pubmed/21265624
(PIs: S.M. Bailey; R.L. Ullrich/M.M. Weil/NSCOR)

6
Eatock RA, Songer JE.
Vestibular hair cells and afferents: Two channels for head motion signals.
Annu Rev Neurosci. 2011 Apr 4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21469959
(PI: J.E. Songer, NSBRI Postdoctoral Fellowship Program)

7
Scott D, Dikici E, Ensor M, Daunert S.
Bioluminescence and its impact in bioanalysis.
Annu Rev Anal Chem (Palo Alto Calif). 2011 Mar 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21456969
(PI: S. Daunert)

Other papers of interest:

1
Rai B, Kaur J.
Salivary stress markers and psychological stress in simulated microgravity: 21 days in 6* head-down tilt.
J Oral Sci. 2011 Mar;53(1):103-7.
http://www.ncbi.nlm.nih.gov/pubmed/21467821
NOTE: Bed rest study. This article may be obtained online without charge.

2
Dieriks B, De Vos WH, Moreels M, Ghardi M, Hennekam R, Broers JL, Baatout S, van Oostveldt P.
Multiplexed profiling of secreted proteins for the detection of potential space biomarkers.
Mol Med Report. 2011 Jan-Feb;4(1):17-23. Epub 2010 Nov 30.
http://www.ncbi.nlm.nih.gov/pubmed/21461557
NOTE: Foton-M3 results.

3
Boyce B.
To boldly go where no food has gone before.
J Am Diet Assoc. 2011 Jan;111(1):45-9.
http://www.ncbi.nlm.nih.gov/pubmed/21185963
NOTE: This article is an interview with Barbara Rice of JSC about NASA's program of food preparation for astronauts.

4
Ikezoe T, Mori N, Nakamura M, Ichihashi N.
Effects of age and inactivity due to prolonged bed rest on atrophy of trunk muscles.
Eur J Appl Physiol. 2011 Apr 7. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21472438
NOTE: Subjects included chronically bedridden individuals.

5
Macpherson PC, Wang X, Goldman D.
Myogenin regulates denervation-dependent muscle atrophy in mouse soleus muscle.
J Cell Biochem. 2011 Apr 4. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21465538

6
Koriak IuA.
[Neuromuscular responses of the triceps surae muscle to prolonged passive stretch of the foot extensor muscles under conditions of simulated microgravity]
Fiziol Zh. 2010;56(5):62-76. Russian.
http://www.ncbi.nlm.nih.gov/pubmed/21265081
NOTE: Bed rest study.

7
Kachaeva EV, Turtikova OV, Leinsoo TA, Shenkman BS.
Insulin-like growth factor 1 and the key markers of proteolysis during the acute period of reloading of the muscle atrophied under disuse.
Biophysics. 2010 Dec;55(6):1006-12.
http://dx.doi.org/10.1134/S0006350910060205
NOTE: This paper is a translation in English of the Russian original published in Biofizika. 2010 Nov-Dec;55(6):1108-16: http://www.ncbi.nlm.nih.gov/pubmed/21268357

8
Ogneva IV, Kurushin VA, Glashev MM, Mikhailova EV, Ponomareva EV, Altaeva EG, Krivoi II, Shenkman BS.
Comparative analysis of structural and functional characteristics of soleus muscle in rats and Mongolian gerbils during gravitational unloading of different duration.
Biophysics. 2010 Dec;55(6):1013-18.
http://dx.doi.org/10.1134/S0006350910060217
NOTE: This paper is a translation in English of the Russian original published in Biofizika. 2010 Nov-Dec;55(6):1117-23: http://www.ncbi.nlm.nih.gov/pubmed/21268358

9
Powers S, Smuder AJ, Criswell DS.
Mechanistic links between oxidative stress and disuse muscle atrophy.
Antioxid Redox Signal. 2011 Apr 3. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21457104

10
Won HY, Lee JA, Park ZS, Song JS, Kim HY, Jang SM, Yoo SE, Rhee Y, Hwang ES, Bae MA.
Prominent bone loss mediated by RANKL and IL-17 produced by CD4+ T cells in TallyHo/JngJ mice.
PLoS One. 2011 Mar 25;6(3):e18168.
http://www.ncbi.nlm.nih.gov/pubmed/21464945
NOTE: This article may be obtained online without charge.

11
Thorpe MP, Evans EM.
Dietary protein and bone health: Harmonizing conflicting theories.
Nutr Rev. 2011 Apr;69(4):215-30.
http://www.ncbi.nlm.nih.gov/pubmed/21457266
NOTE: This article may be obtained online without charge.

12
Patsch JM, Deutschmann J, Pietschmann P.
Gender aspects of osteoporosis and bone strength.
Wien Med Wochenschr. 2011 Mar;161(5-6):117-23.
http://www.ncbi.nlm.nih.gov/pubmed/21461801

13
Suzuki K, Yamaji H, Kobashigawa S, Kawauchi R, Shima K, Kodama S, Watanabe M.
Epigenetic gene silencing is a novel mechanism involved in delayed manifestation of radiation-induced genomic instability in mammalian cells.
Radiat Res. 2011 Apr;175(4):416-23. Epub 2011 Feb 9.
http://www.ncbi.nlm.nih.gov/pubmed/21306201

14
Hellweg CE, Baumstark-Khan C, Schmitz C, Lau P, Meier MM, Testard I, Berger T, Reitz G.
Carbon-ion-induced activation of the NF-B pathway.
Radiat Res. 2011 Apr;175(4):424-31. Epub 2011 Jan 11.
http://www.ncbi.nlm.nih.gov/pubmed/21222514

15
Robbins ME, Bourland JD, Cline JM, Wheeler KT, Deadwyler SA.
A model for assessing cognitive impairment after fractionated whole-brain irradiation in nonhuman primates.
Radiat Res. 2011 Apr;175(4):519-25. Epub 2011 Jan 28.
http://www.ncbi.nlm.nih.gov/pubmed/21275607

16
Birschwilks M, Gruenberger M, Adelmann C, Tapio S, Gerber G, Schofield PN, Grosche B.
The European radiobiological archives: Online access to data from radiobiological experiments.
Radiat Res. 2011 Apr;175(4):526-31. Epub 2011 Jan 25.
http://www.ncbi.nlm.nih.gov/pubmed/21265623

17
Miller D, Reynolds GE, Mejia R, Stark JM, Murnane JP.
Subtelomeric regions in mammalian cells are deficient in DNA double-strand break repair.
DNA Repair (Amst). 2011 Apr 3. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21466975

18
Kornilova LN, Naumov IA, Makarova SM.
Effect of real and simulated weightlessness on the characteristics of the static otolith reflex.
Hum Physiol. 2011 Jan;37(1):85-92.
http://dx.doi.org/10.1134/S0362119711010075
NOTE: ISS results. This paper is a translation in English of the Russian original published in Fiziologiya Cheloveka 2011 Jan-Feb;37(1):97-104: http://www.ncbi.nlm.nih.gov/pubmed/21469359

19
Clemens IA, De Vrijer M, Selen LP, Van Gisbergen JA, Medendorp WP.
Multisensory processing in spatial orientation: An inverse probabilistic approach.
J Neurosci. 2011 Apr 6;31(14):5365-77.
http://www.ncbi.nlm.nih.gov/pubmed/21471371

20
Groeger JA, Lo JC, Burns CG, Dijk DJ.
Effects of sleep inertia after daytime naps vary with executive load and time of day.
Behav Neurosci. 2011 Apr;125(2):252-60.
http://www.ncbi.nlm.nih.gov/pubmed/21463024
NOTE: This article may temporarily be obtained online without charge.

21
Rungarunlert S, Klincumhom N, Bock I, Nemes C, Techakumphu M, Pirity MK, Dinnyes A.
Enhanced cardiac differentiation of mouse embryonic stem cells by use of the slow-turning, lateral vessel (STLV) bioreactor.
Biotechnol Lett. 2011 Apr 8. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21476093

22
Romanchuk SM.
Ultrastructure of the statocytes and cells of distal elongation zone of Arabidopsis thaliana under the conditions of clinorotation.
Cytol Genet. 2010 Dec;44(6):329-33.
http://dx.doi.org/10.3103/S0095452710060010
NOTE: This paper is a translation in English of the Ukrainian original published in Tsitologiya i Genetika 2010 Nov-Dec;44(6):3-8: http://www.ncbi.nlm.nih.gov/pubmed/21254615


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