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NASA Spaceline Current Awareness 8 April 2011 (Recent Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, April 8, 2011

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Papers deriving from NASA support:

1
Das P, Sutherland BM.
Processing of abasic DNA clusters in hApeI-silenced primary fibroblasts exposed to low doses of X-irradiation.
J Biosci. 2011 Mar;36(1):105-16.
http://www.ncbi.nlm.nih.gov/pubmed/21451252
(PI: B.M. Sutherland)
NOTE: This article may be obtained online without charge.

2
Mulavara AP, Fiedler MJ, Kofman IS, Wood SJ, Serrador JM, Peters B, Cohen HS, Reschke MF, Bloomberg JJ.
Improving balance function using vestibular stochastic resonance: Optimizing stimulus characteristics.
Exp Brain Res. 2011 Apr;210(2):303-12. Epub 2011 Mar 26.
http://www.ncbi.nlm.nih.gov/pubmed/21442221
(PI: A.P. Mulavara)

3
Ghosh N, Recker R, Shah A, Bhanu B, Ashwal S, Obenaus A.
Automated ischemic lesion detection in a neonatal model of hypoxic ischemic injury.
J Magn Reson Imaging. 2011 Apr;33(4):772-81.
http://www.ncbi.nlm.nih.gov/pubmed/21448940

4
McGee-Lawrence ME, Stoll DM, Mantila ER, Fahrner BK, Carey HV, Donahue SW.
Thirteen-lined ground squirrels (Ictidomys tridecemlineatus) show microstructural bone loss during hibernation but preserve bone macrostructural geometry and strength.
J Exp Biol. 2011 Apr 15;214(Pt 8):1240-7.
http://www.ncbi.nlm.nih.gov/pubmed/21430199

Other papers of interest:

1
Keller DM, Low DA, Davis SL, Hastings JL, Crandall CG.
Skin surface cooling improves orthostatic tolerance following prolonged head-down bed rest.
J Appl Physiol. 2011 Mar 31. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21454746
NOTE: Bed rest study.

2
Philips JC, Scheen AJ.
Squatting test: A posture to study and counteract cardiovascular abnormalities associated with autonomic dysfunction.
Auton Neurosci. 2011 Mar 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21450535

3
Bigelow C, Stone J.
Bed rest in pregnancy.
Mt Sinai J Med. 2011 Mar/Apr;78(2):291-302.
http://www.ncbi.nlm.nih.gov/pubmed/21425272

4
Arbeille P.
[Deadaptation of the cardiovascular system in microgravity]
Biofutur. 2011 Feb;318:28-30. French.
http://www.biofutur.com/
NOTE: This article is one of 12 short articles, in French, in an issue of this semipopular science magazine. The issue is devoted to topics about travel to Mars, space flight, and the effects of microgravity. To access the Table of Contents, go to the web site link and select volume 318 from the pull-down menu on the left side.

5
Fedorov VB, Goropashnaya AV, Toien O, Stewart NC, Chang C, Wang H, Yan J, Showe LC, Showe MK, Barnes BM.
Modulation of gene expression in heart and liver of hibernating black bears (Ursus americanus).
BMC Genomics. 2011 Mar 31;12:171. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21453527
NOTE: This article may be obtained online without charge.

6
Ferreira JA, Crissey JM, Brown M.
An alternant method to the traditional NASA hindlimb unloading model in mice.
J Vis Exp. 2011 Mar 10;(49). pii: 2467.
http://www.ncbi.nlm.nih.gov/pubmed/21445032
NOTE: This article and video may be obtained online without charge.

7
Eddins MJ, Marblestone JG, Suresh Kumar KG, Leach CA, Sterner DE, Mattern MR, Nicholson B.
Targeting the ubiquitin E3 ligase MuRF1 to inhibit muscle atrophy.
Cell Biochem Biophys. 2011 Mar 30. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21448668

8
Jackson JR, Ryan MJ, Alway SE.
Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice.
J Gerontol A Biol Sci Med Sci. 2011 Mar 31. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21454355

9
Manini TM, Clark BC.
Dynapenia and aging: An update.
J Gerontol A Biol Sci Med Sci. 2011 Mar 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21444359
NOTE: This article may be obtained online without charge.

10
Smith LR, Gerace-Fowler L, Lieber RL.
Muscle extracellular matrix applies a transverse stress on fibers with axial strain.
J Biomech. 2011 Mar 29. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21450292

11
Lu TL, Hu HJ, Zhao W, Chen T.
Synthesis and in vivo bioactivity of lipophilic alendronate derivatives against osteoporosis.
Drug Dev Ind Pharm. 2011 Mar 30. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21449707

12
Bullo M, Estruch R, Salas-Salvado J.
Dietary vitamin K intake is associated with bone quantitative ultrasound measurements but not with bone peripheral biochemical markers in elderly men and women.
Bone. 2011 Mar 27. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21447413

13
Chun KJ.
Bone densitometry.
Semin Nucl Med. 2011 May;41(3):220-8.
http://www.ncbi.nlm.nih.gov/pubmed/21440697

14
Kajimura D, Hinoi E, Ferron M, Kode A, Riley KJ, Zhou B, Guo XE, Karsenty G.
Genetic determination of the cellular basis of the sympathetic regulation of bone mass accrual.
J Exp Med. 2011 Mar 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21444660

15
Vetter A, Witt F, Sander O, Duda GN, Weinkamer R.
The spatio-temporal arrangement of different tissues during bone healing as a result of simple mechanobiological rules.
Biomech Model Mechanobiol. 2011 Mar 24. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21431883

16
Ivanov VN, Ghandhi SA, Zhou H, Huang SX, Chai Y, Amundson SA, Hei TK.
Radiation response and regulation of apoptosis induced by a combination of TRAIL and CHX in cells lacking mitochondrial DNA: A role for NF-B-STAT3-directed gene expression.
Exp Cell Res. 2011 Mar 25. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21440540

17
Moeller R, Setlow P, Pedraza-Reyes M, Okayasu R, Reitz G, Nicholson WL.
Role of the Nfo and ExoA apurinic/apyrimidinic (AP) endonucleases in the radiation resistance and radiation-induced mutagenesis of Bacillus subtilis spores.
J Bacteriol. 2011 Mar 25. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21441501

18
Iwata C, Abe C, Tanaka K, Morita H.
Role of the vestibular system in the arterial pressure response to parabolic-flight-induced gravitational changes in human subjects.
Neurosci Lett. 2011 Mar 25. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21440600
NOTE: Parabolic flight results.

19
Pollock RD, Provan S, Martin FC, Newham DJ.
The effects of whole body vibration on balance, joint position sense and cutaneous sensation.
Eur J Appl Physiol. 2011 Apr 1. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21455611

20
Gao KL, Hui-Chan CW, Tsang WW.
Golfers have better balance control and confidence than healthy controls.
Eur J Appl Physiol. 2011 Mar 17. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21416145

21
Dunn JW, Root DD.
Demonstrating the uses of the novel gravitational force spectrometer to stretch and measure fibrous proteins.
J Vis Exp. 2011 Mar 19;(49). pii: 2624.
http://www.ncbi.nlm.nih.gov/pubmed/21445050

22
Maruthamuthu V, Sabass B, Schwarz US, Gardel ML.
Cell-ECM traction force modulates endogenous tension at cell-cell contacts.
Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4708-13. Epub 2011 Mar 7.
http://www.ncbi.nlm.nih.gov/pubmed/21383129

23
Yang MT, Reich DH, Chen CS.
Measurement and analysis of traction force dynamics in response to vasoactive agonists.
Integr Biol (Camb). 2011 Mar 28. [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/21445393

// end //

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