NASA Spaceline Current Awareness List #644 - 17 April 2015

Status Report From: Spaceline
Posted: Saturday, April 18, 2015


Papers deriving from NASA support:



Diaz A, Trigg C, Young LR.

Combining ergometer exercise and artificial gravity in a compact-radius centrifuge.

Acta Astronaut. 2015 Apr 7. [Article in Press]

PI: L.R. Young

Note: Presented at the 65th International Astronomical Congress, Toronto, Canada, IAC-14-A1.2.10.

Journal Impact Factor: 0.816

Funding: "This project was funded by the MIT/Skolkovo development project." The PI also reports funding through NSBRI NCC 9-58-SA03401.



von Neubeck C, Geniza MJ, Kauer PM, Robinson RJ, Chrisler WB, Sowa MB.

The effect of low dose ionizing radiation on homeostasis and functional integrity in an organotypic human skin model.

Mutat Res. 2015 Mar 16;775:10-8. [Epub ahead of print]

PI: M.B. Sowa

Journal Impact Factor: 4.44

Funding: "This work was supported by the National Aeronautics and Space Administration [NNX10AB06G]; and the Biological and Environmental Research Program (BER), U. S. Department of Energy [DE-AC06-76RLO]."



Johnston JC, Ruthruff E, Lien MC.

Visual information processing from multiple displays.

Hum Factors. 2015 Mar;57(2):276-97. Epub 2014 Aug 4.

Journal Impact Factor: 1.290

Funding: "This research was supported by the NASA Aviation Safety program."  J.C. Johnston is at NASA Ames Research Center.



Wickens CD, Hutchins SD, Laux L, Sebok A.

The impact of sleep disruption on complex cognitive tasks: A meta-analysis.

Hum Factors. 2015 Feb 20. [Epub ahead of print]

PI: A. Sebok

Journal Impact Factor: 1.290

Funding: "This work was funded under NASA Grant NNX12AE69G."



Wickens CD, Sebok A, Li H, Sarter N, Gacy AM.

Using modeling and simulation to predict operator performance and automation-induced complacency with robotic automation: A case study and empirical validation.

Hum Factors. 2015 Jan 12. [Epub ahead of print]

PI: A. Sebok

Journal Impact Factor: 1.290

Funding: "This work was funded under NASA Grant NNX09AM81G."



Scott JM, Haykowsky MJ.

Cardiovascular function and exercise capacity in patients with colorectal cancer: Does anticancer therapy matter?

J Am Coll Cardiol. 2015 Apr 7;65(13):1380-1.

PI: J.M. Scott

Journal Impact Factor: 15.343

Funding: "Support received from the Human Research Program of the National Aeronautics and Space Administration (NASA)."


Cramer L, Hildebrandt B, Springer J, Riess H, Anker SD, von Haehling S.

Reply: Cardiovascular function and exercise capacity in patients with colorectal cancer: Does anticancer therapy matter?

J Am Coll Cardiol. 2015 Apr 7;65(13):1381-2.

Note: These letters comment on the article: Cramer L, Hildebrandt B, Kung T, Wichmann K, Springer J, Doehner W, Sandek A, Valentova M, Stojakovic T, Scharnagl H, Riess H, Anker SD, von Haehling S. Cardiovascular function and predictors of exercise capacity in patients with colorectal cancer. J Am Coll Cardiol. 2014 Sep 30;64(13):1310-9. 




Other papers of interest:



Zhang X, Fang X, Liu C.

Genomic and proteomic analysis of Escherichia coli after spaceflight reveals changes involving metabolic pathways.

Arch Med Res. 2015 Apr 3. [Epub ahead of print]

Note: Shenzhou 8 results.



Kansagra AP, Shute TS.

Space: The final frontier for IR.

J Vasc Interv Radiol. 2015 Mar 31. [Epub ahead of print]

Note: The authors suggest that an interventional radiologist is best suited to provide medical care on a long-duration interplanetary spaceflight.



Suva D, Poizat G.

[Shuttle Challenger disaster: What lessons can be learned for management of patients in the operating room?]

Rev Med Suisse. 2015 Feb 4;11(460):367-70. French.

Note: From the abstract: “For many years hospitals have been implementing crew resource management (CRM) programs, inspired by the aviation industry, in order to improve patient safety…By analyzing the space shuttle Challenger accident, the objective of this article is to show the potential impact of the professional culture in decision-making processes.”



Papadopoulou V, Evgenidis S, Eckersley RJ, Mesimeris T, Balestra C, Kostoglou M, Tang MX, Karapantsios TD.

Decompression induced bubble dynamics on ex vivo fat and muscle tissue surfaces with a new experimental set up.

Colloids Surf B Biointerfaces. 2015 Mar 24;129:121-9. [Epub ahead of print]



Pollonini L, Padhye NS, Re R, Torricelli A, Simpson RJ, Dacso CC.

Pulse transit time measured by photoplethysmography improves the accuracy of heart rate as a surrogate measure of cardiac output, stroke volume and oxygen uptake in response to graded exercise.

Physiol Meas. 2015 Apr 9;36(5):911-24. [Epub ahead of print]



Amorim ED, Peras VR, de Andrade O, Martins-Pinge MC.

Functional evidence of paraventricular nucleus involvement in cardiovascular and autonomic modulation in response to acute microgravity (head-down tilt) in unanesthetized rats.

J Neurosci Res. 2015 Mar 28. [Epub ahead of print]

Note: In the head-down tilt (HDT) protocol, the animals were placed in a cylindrical housing of approximately 30 cm, fixed on a movable platform in a horizontal position, then subjected to HDT by raising the platform on the side where the animal's tail was to -75° tilt position and maintained in that position for 15 min. 



Ohira T, Kawano F, Ohira T, Goto K, Ohira Y.

Responses of skeletal muscles to gravitational unloading and/or reloading.

J Physiol Sci. 2015 Apr 8. [Epub ahead of print] Review.

Note: The authors review human and animal studies, including spaceflight, bed rest, and hindlimb unloading results.



McKeon-Fischer KD, Browe DP, Olabisi RM, Freeman JW.

Poly(3,4-ethylenedioxythiophene) nanoparticle and poly(ε-caprolactone) electrospun scaffold characterization for skeletal muscle regeneration.

J Biomed Mater Res A. 2015 Apr 9. [Epub ahead of print]



Sato EJ, Killian ML, Choi AJ, Lin E, Choo AD, Rodriguez-Soto AE, Lim CT, Thomopoulos S, Galatz LM, Ward SR.

Architectural and biochemical adaptations in skeletal muscle and bone following rotator cuff injury in a rat model.

J Bone Joint Surg Am. 2015 Apr 1;97(7):565-73.



Seref-Ferlengez Z, Kennedy OD, Schaffler MB.

Bone microdamage, remodeling and bone fragility: How much damage is too much damage?

Bonekey Rep. 2015 Mar 18;4:644. Review.

Note: This article may be obtained online without charge.



de Rooij KE, van der Velde M, de Wilt E, Deckers MM, Bezemer M, Waarsing JH, Que I, Chan AB, Kaijzel EL, Lowik CW.

Identification of receptor-type protein tyrosine phosphatase µ as a new marker for osteocytes.

Histochem Cell Biol. 2015 Apr 8. [Epub ahead of print]

Note: This article may be obtained online without charge.



Deng M, Liu P, Xiao H, Zhang Y, Wang Y, Zhao J, Xu J.

Improving the osteogenic efficacy of BMP2 with mechano growth factor by regulating the signaling events in BMP pathway.

Cell Tissue Res. 2015 Apr 7. [Epub ahead of print]



Erdemir A, Bennetts C, Davis S, Reddy A, Sibole S.

Multiscale cartilage biomechanics: Technical challenges in realizing a high-throughput modelling and simulation workflow.

Interface Focus. 2015 Apr 6;5(2):20140081.



McGarvie LA, Martinez-Lopez M, Burgess AM, MacDougall HG, Curthoys IS.

Horizontal eye position affects measured vertical VOR gain on the video head impulse test.

Front Neurol. 2015 Mar 17;6:58.

Note: This article may be obtained online without charge.



Shinde V, Yegnanarayan R, Shah P, Gupta A, Pophale P.

Antidepressant-like activity of flunarizine in modified tail suspension test in rats.

N Am J Med Sci. 2015 Mar;7(3):100-3.

Note: Hindlimb unloading study. This article may be obtained online without charge.



Wu R, Wang Y.

Psychosocial interaction during a 105-day isolated mission in Lunar Palace 1.

Acta Astronaut.  Apr 6. [Article in Press]

Note: Data are from the Chinese Lunar Palace 1 isolation study.



Slobodian RE.

Selling space colonization and immortality: A psychosocial, anthropological critique of the rush to colonize Mars.

Acta Astronaut. 2015 Apr 6. [Article in Press]

Note: From the Introduction: "I will examine and critique the stories and motivations behind the postulated need for humanity to survive through colonization, the importance of fear and marketing, and ultimately how humans should proceed to colonize space."



Tsuchiya N, Kodama D, Goto S, Togari A.

Shear stress-induced Ca(2+) elevation is mediated by autocrine-acting glutamate in osteoblastic MC3T3-E1 cells.

J Pharmacol Sci. 2015 Mar;127(3):311-8. Epub 2015 Feb 7.

Note: This article may be obtained online without charge.



Isaacson J, Brotto M.

Physiology of mechanotransduction: How do muscle and bone "talk" to one another?

Clin Rev Bone Miner Metab. 2014 Jun;12(2):77-85.

Note: This article may be obtained online without charge.


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