NASA Spaceline Current Awareness List #653 - 19 June 2015

Status Report From: Spaceline
Posted: Friday, June 19, 2015

Editor's note: NASA's various life sciences programs have prepared the SPACELINE Current Awareness updates since 1999 covering all aspects of space life science, gravitational biology, space medicine, and human factors since 1999. NASA does not maintain a website - nor does it have an  archive of this resource online. However, SpaceRef does have a complete archive of SPACELINE updates all the way back to 1999 that can be accessed here:


Papers deriving from NASA support:



Kim JH, Lee Y, Kwak HB, Lawler JM.

Lifelong wheel running exercise and mild caloric restriction attenuate nuclear EndoG in the aging plantaris muscle.

Exp Gerontol. 2015 Jun 6. [Epub ahead of print]

PI: J.M. Lawler

Journal Impact Factor: 3.529

Funding: "This work has been supported by grants from NIH (AR054084) (J.M.L.), NASA (NNX12AR62G) (J.M.L.), the Sydney and J.L. Huffines Institute (J.H.K., J.M.L.) at Texas A&M University, and Hanyang University (HY-2015, J.H.K.)."



Hu M, Tian GW, Gibbons DE, Jiao J, Qin YX.

Dynamic fluid flow induced mechanobiological modulation of in situ osteocyte calcium oscillations.

Arch Biochem Biophys. 2015 Jun 1;579:55-61. [Epub ahead of print]

PI: Y.X. Qin

Journal Impact Factor: 3.043

Funding: "This research is kindly supported by the National Institute of Health (R01 AR52379 and AR61821, YXQ), the US Army Medical Research and Materiel Command, and the National Space Biomedical Research Institute through NASA Cooperative Agreement NCC 9-58 (YXQ)."



Chen H, Goodus MT, de Toledo SM, Azzam EI, Levison SW, Souayah N.

Ionizing radiation perturbs cell cycle progression of neural precursors in the subventricular zone without affecting their long-term self-renewal.

ASN Neuro. 2015 Jun;7(3).

PI: E. Azzam

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.436

Funding: "This work was supported in part by RAM Capital II, startup fund from the Department of Neurology and Neurosciences at NJMS to NS, grant HD052064 from the National Institute of Child Health, and a grant from the Leducq Foundation to SWL. EIA is supported by grant CA049062 from the National Institutes of Health and grant NNX15AD62G from NASA."



Kim M-HY, Plante I.

An assessment of how radiation incurred during a Mars mission could affect food and pharmaceuticals.

PI: S. Blattnig

Note: This article may be obtained online without charge.

Journal Impact Factor: Not applicable

Funding: "This work was supported by NASA risk assessment project NAS9-02078."



Straume T.

Medical concerns with space radiation and radiobiological effects.

In: Handbook of Cosmic Hazards and Planetary Defense. Cham, Switzerland: Springer International Publishing, 2015. p. 259-93.

Journal Impact Factor: Not applicable

Funding: T. Straume is at NASA Ames Research Center.



Slaba TC, Blattnig SR, Norbury JW, Rusek A, La Tessa C, Walker SA.

GCR simulator reference field and a spectral approach for laboratory simulation.

Hampton, VA: NASA Langley Research Center, Mar 2015. 31 p. NASA/TP-2015-218698.

Journal Impact Factor: Not applicable

Funding: T.C. Slaba, S.R. Blattnig, and J.W. Norbury are at NASA Langley Research Center.



Chartrand T, McCollum G, Hanes DA, Boyle RD.

Symmetries of a generic utricular projection: Neural connectivity and the distribution of utricular information.

J Math Biol. 2015 Jun 10. [Epub ahead of print]

PI: R.D. Boyle

Journal Impact Factor: 2.386

Funding: "RDB gratefully acknowledges the support of NASA 03-OBPR-04 grant and NASA Human Research Program."



Kozlowski SWJ, Chao GT, Chang C-H, Fernandez R.

Team dynamics: Using "big data" to advance the science of team effectiveness.

In: Big data at work: The data science revolution and organizational psychology. SIOP Organizational Frontiers Series. New York, NY: Routledge Academic, 2015. [In Press]. 

PI: S.W.J. Kozlowski

Journal Impact Factor: Not applicable

Funding: "We gratefully acknowledge the Agency for Health Research and Quality (AHRQ; 1R18HS020295-01, R. Fernandez, Principal Investigator, S. W. J. Kozlowski, Co-Investigator and HS022458-01A1, R. Fernandez, Principal Investigator, G. T. Chao, Co-Investigator ), the Army Research Institute (ARI; W911NF-14-1-0026, S.W.J. Kozlowski and G. T. Chao, Principal Investigators), the National Aeronautics and Space Administration (NASA; NNX09AK47G, NNX12AR15G & NNX13AM77G, S.W.J. Kozlowski, Principal Investigator, S. Biswas and C.-H. Chang, Co-Investigators), and the Office of Naval Research (ONR), Command Decision Making (CDM) Program (N00014-09-1-0519, S.W.J. Kozlowski and G. T. Chao, Principal Investigators) for support that, in part, assisted the composition of this chapter."



Kozlowski SWJ, Grand JA, Baard SK, Pearce M.

Teams teamwork, and team effectiveness: Implications for human systems integration.

In: The Handbook of Human Systems Integration. APA Handbooks in Psychology Series; APA Reference Books Series. Washington, DC: American Psychological Association, 2015.

PI: S.W.J. Koslowski

Journal Impact Factor: Not applicable

Funding: "Steve W. J. Kozlowski gratefully acknowledges the National Aeronautics and Space Administration (NASA, NNX12AR15G, NNX13AM77G, S.W.J. Kozlowski, Principal Investigator) and the Office of Naval Research (ONR), Command Decision Making (CDM) Program (N00014-09-1-0519, S.W.J. Kozlowski and G. T. Chao, Principal Investigators ) for support that, in part, assisted the composition of this chapter."



Schuerger AC, Lee P.

Microbial ecology of a crewed rover traverse in the Arctic: Low microbial dispersal and implications for planetary protection on human Mars missions.

Journal Impact Factor: 2.512

Funding: "The research was supported by two research grants (NNX12AJ84G and NNX08AQ81A) from NASA’s Planetary Protection Office and through a Cooperative Agreement (NNX08AO59A) by NASA’s Human Exploration and Operations Mission Directorate (HEOMD). The NASA Haughton Mars Project and the Northwest Passage Drive Expedition (NWPDX) were sponsored by the Mars Institute, the SETI Institute, and the National Aeronautics and Space Administration (NASA)."



Other papers of interest:



Barabanov V, Gulimova V, Berdiev R, Saveliev S.

Object play in thick-toed geckos during a space experiment.

J Ethol. 2015 May;33(2):109-15. Epub 2015 Mar 26.

Note: Bion-M1 results.



Brandt A, de Vera J-P, Onofri S, Ott S.

Viability of the lichen Xanthoria elegans and its symbionts after 18 months of space exposure and simulated Mars conditions on the ISS.

Int J Astrobiology. 2015 Jul;14(03):411-25.

Note: ISS results.



Li T, Chang D, Xu H, Chen J, Su L, Guo Y, Chen Z, Wang Y, Wang L, Wang J, Fang X, Liu C.

Impact of a short-term exposure to spaceflight on the phenotype, genome, transcriptome and proteome of Escherichia coli.

Int J Astrobiology. 2015 Jul;14(3):435-44.

Note: The spaceflight is not identified.



Martynova MG, Shabelnikov SV, Bystrova OA.

Long-term consequences of a short-term hypergravity load in a snail model.

Int J Astrobiology. 2015 Jul;14(03):489-95.

Note: Centrifugation was used.



Styner M, Pagnotti GM, Galior K, Wu X, Thompson WR, Uzer G, Sen B, Xie Z, Horowitz MC, Styner MA, Rubin C, Rubin J.

Exercise regulation of marrow fat in the setting of PPARgamma agonist treatment in female C57BL/6 mice.

Note: This article may be obtained online without charge.



Zhou S, Zu Y, Sun Z, Zhuang F, Yang C.

Effects of hypergravity on osteopontin expression in osteoblasts.

PLoS One. 2015 Jun 5;10(6):e0128846.

Note: Centrifugation was used.This article may be obtained online without charge.



Prakash M, Fried R, Götze O, May F, Frings-Meuthen P, Mulder E, Valentini J, Fox M, Fried M, Schwizer W, Misselwitz B.

Microgravity simulated by the 6° head-down tilt bed rest test increases intestinal motility but fails to induce gastrointestinal symptoms of space motion sickness.

Dig Dis Sci. 2015 Jun 9. [Epub ahead of print]

Note: Bed rest study.



Belavý DL, Baecker N, Armbrecht G, Beller G, Buehlmeier J, Frings-Meuthen P, Rittweger J, Roth HJ, Heer M, Felsenberg D.

Serum sclerostin and DKK1 in relation to exercise against bone loss in experimental bed rest.

J Bone Miner Metab. 2015 Jun 9. [Epub ahead of print]

Note: Bed rest study.



Aceto J, Nourizadeh-Lillabadi R, Marée R, Dardenne N, Jeanray N, Wehenkel L, Aleström P, van Loon JJ, Muller M.

Zebrafish bone and general physiology are differently affected by hormones or changes in gravity.

PLoS One. 2015;10(6):e0126928. Epub Jun 10.

Note: A Large Diameter Centrifuge was used; the fish also were treated with parathyroid hormone and Vitamin D3. This article may be obtained online without charge.



Erben RG.

Hypothesis: Coupling between resorption and formation in cancellous bone remodeling is a mechanically controlled event.

Front Endocrinol (Lausanne). 2015 May 20;6:82.

Note: This article may be obtained online without charge.



Luan H-Q, Sun L-W, Huang Y-F, Wu X-t, Haijun N, Liu H, Fan Y-B.

Use μCT to evaluate exercise effects on preventing degeneration of articular cartilage in tail-suspended rats.

Life Sci Space Res. 2015 Jun 9. [Article in Press]

Note: Hindlimb suspension was used.



Sarma S, Levine BD.

Soothing the sleeping giant: Improving skeletal muscle oxygen kinetics and exercise intolerance in HFpEF.

J Appl Physiol (1985). 2015 Jun 5:jap.01127.2014. [Epub ahead of print]



Yoshikawa Y, Yamasaki A, Takatori K, Suzuki M, Kobayashi J, Takao M, Zhang-Akiyama QM.

Excess processing of oxidative damaged bases hypersensitivity to oxidative stress and low dose rate irradiation.

Free Radic Res. 2015 Jun 10:1-36. [Epub ahead of print]



Pinsky L.

Monte Carlo transport codes for use in the space radiation environment.

Note: This article may be obtained online without charge.



Herman JP, Bogadhi AR, Krauzlis RJ.

Effects of spatial cues on color-change detection in humans.

J Vis. 2015 May 1;15(6):3.

Note: This article may be obtained online without charge.



Zhang Y, Fang B, Emmett MJ, Damle M, Sun Z, Feng D, Armour SM, Remsberg JR, Jager J, Soccio RE, Steger DJ, Lazar MA.

Discrete functions of nuclear receptor Rev-erbalpha couple metabolism to the clock.



Zhao X, Wang J, Yuan J, Wang X-l, Zhao Q-p, Kong P-t, Zhang X.

NITRIC OXIDE-ASSOCIATED PROTEIN1 (AtNOA1) is essential for salicylic acid-induced root waving in Arabidopsis thaliana.

New Phytol. 2015 Jul;207(1):211-24.



Vinterhalter D, Vinterhalter B, Miljuš-Djukić J, Jovanović Z, Orbović V.

Erratum to: Daily changes in the competence for photo- and gravitropic response by potato plantlets (vol 33, pg 539, 2014).

J Plant Growth Regul. 2015 Jun;34(2):440-50.

Note: From the publisher: "Due to the inadvertent publication of the article in its uncorrected form, the article is now republished. This erratum contains the corrected version and is the version of record." The original version was published in Volume 33, p. 539, 2014.



Soh H, Srikanth K, Whang SS, Lee S.

Morphological and gene expression pattern changes in wrky46 mutant Arabidopsis thaliana under altered gravity conditions.

Note: 3D clinorotation was used.



Lee HW, Cho C, Kim J.

LBD16 and LBD18 act downstream of the AUX1 and LAX3 auxin influx carriers to control lateral root development in Arabidopsis thaliana.

Plant Physiol. 2015 Jun 9. [Epub ahead of print]



Ivanovska IL, Shin JW, Swift J, Discher DE.

Stem cell mechanobiology: Diverse lessons from bone marrow.

Trends Cell Biol. 2015 Jun 1. [Epub ahead of print] Review.

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