NASA SPACELINE Current Awareness List #656 10 July 2015

Status Report From: Spaceline
Posted: Friday, July 10, 2015

Editor's note: NASA's various life sciences programs have prepared the SPACELINE Current Awareness updates since 1999 covering all aspects of space life science, gravitational biology, space medicine, and human factors. NASA does not maintain a website - nor does it have an  archive of this resource online. However, SpaceRef does have a complete archive of SPACELINE updates all the way back to 1999 that can be accessed here:

Papers deriving from NASA support:



Gridley DS, Mao XW, Tian J, Cao JD, Perez C, Stodieck LS, Ferguson VL, Bateman TA, Pecaut MJ.

Genetic and apoptotic changes in lungs of mice flown on the STS-135 mission in space.

In Vivo. 2015 Jul 8;29(4):423-33.

PI: D.S. Gridley

Note: STS-135 results.

Journal Impact Factor: 0.974

Funding: NASA’s Space Biology Program provided the tissues via the NASA Biospecimen Sharing Program; Amgen funded the flight mission.



Strewe C, Crucian BE, Sams CF, Feuerecker B, Stowe RP, Choukèr A, Feuerecker M.

Hyperbaric hyperoxia alters innate immune functional properties during NASA Extreme Environment Mission Operation (NEEMO).

Brain Behav Immun. 2015 Jun 25. [Epub ahead of print]

PI: C.F. Sams

Journal Impact Factor: 5.889

Funding: "This investigation has been supported by the ESA, NASA, the German National Space Program (DLR, 50WB0719/WB0919) and by the NEEMO crews, surface operators (B. Todd) and organizer who all supported the study with high professionalism and great enthusiasm."



Clément GR, Bukley AP, Paloski WH.

Artificial gravity as a countermeasure for mitigating physiological deconditioning during long-duration space missions.

Front Syst Neurosci. 2015 Jun 17;9:92. Review.

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: W.H. Paloski is at NASA Johnson Space Center.



Basner M, McGuire S, Goel N, Rao H, Dinges DF.

A new likelihood ratio metric for the psychomotor vigilance test and its sensitivity to sleep loss.

J Sleep Res. 2015 Jun 29. [Epub ahead of print]

PI: M. Basner

Journal Impact Factor: 3.347

Funding: "This investigation was sponsored by the Human Factors Program of the Transportation Security Laboratory, Science and Technology Directorate, US Department of Homeland Security (FAA #04-G-010), by NIH grants R01 NR004281, R01 HL102119 and UL1 RR024134, and in part by the National Space Biomedical Research Institute through NASA NCC 9-58, the Office of Naval Research through ONR N00014-11-1-0361 and NASA through NASA NNX14AM81G."



Other papers of interest:



Yijing Z, Xiaoping D, Fang L, Xiaolu J, Bin W.

The effects of guided imagery on heart rate variability in simulated spaceflight emergency tasks performers.

Biomed Res Int. 2015;2015:687020. Epub 2015 Jun 7.

Note: Participants performed nine sedentary spaceflight emergency tasks using either instructor- or self-guided imagery. This article may be obtained online without charge.



van Breukelen F, Martin SL.

The hibernation continuum: Physiological and molecular aspects of metabolic plasticity in mammals.

Physiology (Bethesda). 2015 Jul;30(4):273-81. Review.



Sugita T, Yamazaki T, Yamada S, Takeoka H, Cho O, Tanaka T, Ohno G, Watanabe K, Makimura K, Ohshima H, Ishioka N, Mukai C.

Temporal changes in the skin Malassezia microbiota of members of the Japanese Antarctic Research Expedition (JARE): A case study in Antarctica as a pseudo-space environment.

Med Mycol. 2015 Jun 30. [Epub ahead of print]



Zhou L, Zhou W, Zhang S, Liu B, Liang P, Zhou Y, Zhou T, Zhang K, Leng Y, Kong W.

BDNF signaling in the rat cerebello-vestibular pathway during vestibular compensation: BDNF signaling in vestibular compensation.

FEBS J. 2015 Jun 26. [Epub ahead of print]



Sasso JP, Eves ND, Christensen JF, Koelwyn GJ, Scott J, Jones LW.

A framework for prescription in exercise-oncology research.

J Cachexia Sarcopenia Muscle. 2015 Jun;6(2):115-24. Epub 2015 May 11.

Note: This article may be obtained online without charge.



Dupré-Aucouturier S, Castells J, Freyssenet DG, Desplanches D.

Trichostatin A, a histone deacetylase inhibitor, modulates unloaded-induced skeletal muscle atrophy.

J Appl Physiol (1985). 2015 Jun 25:jap.01031.2014. [Epub ahead of print]

Note: Hindlimb unloading was used.



Siebert T, Leichsenring K, Rode C, Wick C, Stutzig N, Schubert H, Blickhan R, Böl M.

Three-dimensional muscle architecture and comprehensive dynamic properties of rabbit gastrocnemius, plantaris and soleus: Input for simulation studies.

PLoS One. 2015 Jun 26;10(6):e0130985.

Note: This article may be obtained online without charge.



Siamwala JH, Rajendran S, Chatterjee S.

Strategies of manipulating BMP signaling in microgravity to prevent bone loss.

Vitam Horm. 2015 Jun 25. [Article in Press] Review.

Note: The authors discuss the basic bone morphobgenetic protein (BMP) structure, its significance in bone repair, and stem cell differentiation during spaceflight, hindlimb unloading, and clinorotation.



Rosa N, Simoes R, Magalhães FD, Marques AT.

From mechanical stimulus to bone formation: A review.

Med Eng Phys. 2015 Jun 24. [Epub ahead of print] Review.



Ren L, Yang P, Wang Z, Zhang J, Ding C, Shang P.

Biomechanical and biophysical environment of bone from the macroscopic to the pericellular and molecular level.

J Mech Behav Biomed Mater. 2015 Apr 24;50:104-22. [Epub ahead of print] Review.



Cheng JH, Wang CJ.

Biological mechanism of shockwave in bone.

Int J Surg. 2015 Jun 25. [Epub ahead of print]



Kim MH, Rusek A, Cucinotta FA.

Issues for simulation of galactic cosmic ray exposures for radiobiological research at ground-based accelerators.

Front Oncol. 2015 Jun 4;5:122.

Note: This article may be obtained online without charge.



Gustafsson AS, Hartman T, Stenerlöw B.

Formation and repair of clustered damaged DNA sites in high LET irradiated cells.

Int J Radiat Biol. 2015 Jul 1:1-26. [Epub ahead of print]



Song KH, Kim MH, Kang SM, Jung SY, Ahn J, Woo HJ, Nam SY, Hwang SG, Ryu SY, Song JY.

Analysis of immune cell populations and cytokine profiles in murine splenocytes exposed to whole-body low-dose irradiation.

Int J Radiat Biol. 2015 Jul 1:1-27. [Epub ahead of print]



Liu Q, Zhou R, Liu L, Zhao X.

Effects of 72 hours total sleep deprivation on male astronauts' executive functions and emotion.

Compr Psychiatry. 2015 Jun 3. [Epub ahead of print]



Estes S.

The workload curve: Subjective mental workload.

Hum Factors. 2015 Jun 30. [Epub ahead of print]



Wang M, Fu Y, Liu H.

Nutritional quality and ions uptake to PTNDS in soybeans.

Food Chem. 2015 Jul 3. [Article in Press]



Kovalev VS, Manukovsky NS, Tikhomirov AA, Kolmakova AA.

Modeling snail breeding in a bioregenerative life support system.

Life Sci Space Res. 2015 Jun 30. [Article in Press]

Note: Snails are suggested as a means of reducing biomass and for protein consumption during spaceflight.



Rasmussen T, Rasmussen A, Singh S, Galbiati H, Edwards MD, Miller S, Booth IR.

Properties of the mechanosensitive channel MscS pore revealed by tryptophan scanning mutagenesis.



Duck G, Kovacevic A, Robertson DL, Stevens R, Nenadic G.

Ambiguity and variability of database and software names in bioinformatics.

J Biomed Semantics. 2015 Jun 29;6:29.

Note: This article may be obtained online without charge.


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