NASA Spaceline Current Awareness List #659 31 July 2015

Status Report From: Spaceline
Posted: Friday, July 31, 2015

Papers deriving from NASA support:

Wotring VE.
Medication use by U.S. crewmembers on the International Space Station.
FASEB J. 2015 Jul 17. [Epub ahead of print]
PI: V.E. Wotring
Note: ISS results.
Journal Impact Factor: 5.043
Funding: "This study was funded by the Human Research Program of the U.S. National Aeronautics and Space Administration (NASA)."

Luna C, Yew AG, Hsieh AH.
Effects of angular frequency during clinorotation on mesenchymal stem cell morphology and migration.
npj Microgravity. 2015 Jul 30;1:15007.
PI: A.H. Hsieh
Note: Clinorotation was used. This article may be obtained online without charge.
Journal Impact Factor: Not available for this journal
Funding: "This work was supported by National Aeronautics and Space Administration Space Biology Program, Grant NNX13AM06G."

Radford NB, DeFina LF, Barlow CE, Kerr A, Chakravorty R, Khera A, Levine BD.
Effect of fitness on incident diabetes from statin use in primary prevention.
Atherosclerosis. 2015 Mar;239(1):43-9. Epub 2014 Dec 23.
PI: B.D. Levine
Journal Impact Factor: 3.994
Funding: "This study was supported by grant CA 02201 from the National Space Biomedical Research Institute (NSBRI)."

Jafri MA, Zaidi SK, Ansari SA, Al-Qahtani MH, Shay JW.
MicroRNAs as potential drug targets for therapeutic intervention in colorectal cancer.
Expert Opin Ther Targets. 2015 Jul 18:1-19. Review. [Epub ahead of print]
PIs: A.J. Fornace/J.W. Shay/NSCOR
Journal Impact Factor: 5.139
Funding: "JW Shay has received funding from a NASA grant (NNX15AI21G)."

Shirazi-Fard Y, Alwood JS, Schreurs AS, Castillo AB, Globus RK.
Mechanical loading causes site-specific anabolic effects on bone following exposure to ionizing radiation.
Bone. 2015 Jul 18. [Epub ahead of print]
PI: R.K. Globus
Journal Impact Factor: 3.973
Funding: "This work is supported by the National Space Biomedical Research Institute through NCC 9-58, grant MA02501."

Roberts DR, Zhu X, Tabesh A, Duffy EW, Ramsey DA, Brown TR.
Structural brain changes following long-term 6º head-down tilt bed rest as an analog for spaceflight.
AJNR Am J Neuroradiol. 2015 Jul 16. [Epub ahead of print]
PI: D.R. Roberts
Note: Bed rest study. This article may be obtained online without charge.
Journal Impact Factor: 3.589
Funding: "This work was funded by NASA, grant number NNJ04HF70G."

Other papers of interest:

Bogomolov VV, Kondratenko SN, Kovachevich IV.
[Testing stability of tableted acetaminophen and furosemide after 6-month storage in space flight].
Aviakosm Ekolog Med. 2015;49(2):12-5. Russian.
Note: ISS results.

Buzmakov A, Chukalina M, Nikolaev D, Gulimova V, Saveliev S, Tereschenko E, Seregin A, Senin R, Zolotov D, Prun V, Shaefer G, Asadchikov V.
Monochromatic computed microtomography using laboratory and synchrotron sources and X-ray fluorescence analysis for comprehensive analysis of structural changes in bones.
J Appl Crystallogr. 2015 May 31;48(Pt 3):693-701.
Note: FOTON results. This article may be obtained online without charge.

Inozemtsev KO, Kushin VV, Tolochek RV, Shurshakov VA.
[Measurement of space radiation doses and linear energy transfer spectra inside biological satellite Bion-M1].
Aviakosm Ekolog Med. 2015;49(2):16-22. Russian. 582
Note: Bion-M1 results.

Soldatov PE, Dadasheva OA, Gurieva TS, Markin AA, Tatarkin SV, Nosovskii AM, Smirnov IA, Tiurin-Kuzmin A, Shulagin YA, Smolenskaia TS, Grishin VI.
[Testing the protective properties of argon during subacute exposure to hypoxic hypoxia].
Aviakosm Ekolog Med. 2015;49(2):23-31. Russian.

Gjorevski N, A SP, Varner VD, Nelson CM.
Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices.
Sci Rep. 2015 Jul;5:11458.
Note: This article may be obtained online without charge.

Marchand N, Collins CH.
Synthetic quorum sensing and cell-cell communication in gram-positive Bacillus megaterium.
ACS Synth Biol. 2015 Jul 23. [Epub ahead of print]

Scimeca M, Bonanno E, Piccirilli E, Baldi J, Mauriello A, Orlandi A, Tancredi V, Gasbarra E, Tarantino U.
Satellite cells CD44 positive drive muscle regeneration in osteoarthritis patients.
Stem Cells Int. 2015;2015:469459. Epub 2015 Jun 1.
Note: This article may be obtained online without charge.

Canciani B, Ruggiu A, Giuliani A, Panetta D, Marozzi K, Tripodi M, Salvadori PA, Cilli M, Ohira Y, Cancedda R, Tavella S.
Effects of long time exposure to simulated micro- and hypergravity on skeletal architecture.
J Mech Behav Biomed Mater. 2015 Jun 23;51:1-12. [Epub ahead of print]
Note: Hindlimb unloading and centrifugation were used.

Harmata AJ, Ma Y, Sanchez CJ, Zienkiewicz KJ, Elefteriou F, Wenke JC, Guelcher SA.
D-amino acid inhibits biofilm but not new bone formation in an ovine model.
Clin Orthop Relat Res. 2015 Jul 23. [Epub ahead of print]

Katsumura S, Ezura Y, Izu Y, Shirakawa J, Miyawaki A, Harada K, Noda M.
Beta adrenergic receptor stimulation suppresses cell migration in association with cell cycle transition in osteoblasts - Live imaging analyses based on FUCCI system.
J Cell Physiol. 2015 Jul 20. [Epub ahead of print]

Parajuli A, Liu C, Li W, Gu X, Lai X, Pei S, Price C, You L, Lu XL, Wang L.
Bone's responses to mechanical loading are impaired in type 1 diabetes.
Bone. 2015 Jul 13;81:152-60. [Epub ahead of print]
Note: Unilateral axial ulnar loading was used.

Sansalone V, Gagliardi D, Desceliers C, Bousson V, Laredo JD, Peyrin F, Haïat G, Naili S.
Stochastic multiscale modelling of cortical bone elasticity based on high-resolution imaging.
Biomech Model Mechanobiol. 2015 Jul 23. [Epub ahead of print]

Yang X, Sun L-W, Wu X-T, Liang M, Fan Y-B.
Impact of shear stress and simulated microgravity on osteocytes using a new rotation cell culture device.
Acta Astronaut. 2015 Jul 26. [Article in Press]
Note: From the abstract: "To investigate how osteocytes respond to shear stress under weightlessness, a novel custom-made [rotation] device was designed to simulate microgravity and load fluid flow on cells in vitro at the same time."

Tou JC.
Evaluating resveratrol as a therapeutic bone agent: Preclinical evidence from rat models of osteoporosis.
AnnNY Acad Sci. 2015. [Article in Press] Review.
Note: Hindlimb unloading was used.

Yang Z, Zhu S.
[Recent progress of weightlessness impact on the eye].
Zhonghua Yan Ke Za Zhi. 2015 Apr;51(4):310-3. Chinese.
Note: The type of weightlessness is not specified in the abstract.

Kim HS, Paik MJ, Lee YH, Lee YS, Choi HD, Pack JK, Kim N, Ahn YH.
Eight hours of nocturnal 915 MHz radiofrequency identification (RFID) exposure reduces urinary levels of melatonin and its metabolite via pineal arylalkylamine N-acetyltransferase activity in male rats.
Int J Radiat Biol. 2015 Jul 20:1-40. [Epub ahead of print]

Thuraisingham RA.
Dense neuron system interacting with the gravitational potential.
J Theor Biol. 2015 Jul 15. [Epub ahead of print]
Note: From the Introduction: "The study is carried out theoretically by examining the effect of gravitational interaction on a dense neuron system consisting of activated and non-activated neurons."

Salomon R, Kaliuzhna M, Herbelin B, Blanke O.
Balancing awareness: Vestibular signals modulate visual consciousness in the absence of awareness.
Conscious Cogn. 2015 Jul 20;36:289-97. [Epub ahead of print]
Note: A rotating chair was used.

Romero-Carvajal A, Navajas Acedo J, Jiang L, Kozlovskaja-Gumbriene A, Alexander R, Li H, Piotrowski T.
Regeneration of sensory hair cells requires localized interactions between the Notch and Wnt pathways.
Dev Cell. 2015 Jul 14. [Epub ahead of print]

Ireland RG, Simmons CA.
Human pluripotent stem cell mechanobiology: Manipulating the biophysical microenvironment for regenerative medicine and tissue engineering applications.
Stem Cells. 2015 Jul 20. [Epub ahead of print] Review.

Suslak TJ, Watson S, Thompson KJ, Shenton FC, Bewick GS, Armstrong JD, Jarman AP.
Piezo is essential for amiloride-sensitive stretch-activated mechanotransduction in larval Drosophila dorsal bipolar dendritic sensory neurons.
PLoS One. 2015 Jul 17;10(7):e0130969.
Note: This article may be obtained online without charge.

Ushakov IB, Poliakov AV, Usov VM, Boiarintsev VV.
[The prospects for using simulation technologies on manned spacecraft for effective training and refreshing cosmonauts' skills in providing the emergency medical aid].
Aviakosm Ekolog Med. 2015;49(2):50-4. Russian.

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