Posted: Friday, December 4, 2015
Papers deriving from NASA support:
Hackney KJ, Scott JM, Hanson AM, English KL, Downs ME, Ploutz-Snyder LL.
The astronaut-athlete: Optimizing human performance in space.
J Strength Cond Res. 2015 Dec;29(12):3531-45. Review.
PI: L.L. Ploutz-Snyder
Note: ISS and Shuttle results. This article may be obtained online without charge.
Journal Impact Factor: 2.075
Funding: "This work was partially funded by North Dakota NASA Experimental Program to Stimulate Competitive Research (EPSCoR) to K. J. Hackney." The PI also acknowledges both NSBRI and NASA for funding that contributed to ideas expressed in the paper.
Zhang C, Brown MQ, van de Ven W, Zhang ZM, Wu B, Young MC, Synek L, Borchardt D, Harrison R, Pan S, Luo N, Huang YM, Ghang YJ, Ung N, Li R, Isley J, Morikis D, Song J, Guo W, Hooley RJ, Chang CA, Yang Z, Zarsky V, Muday GK, Hicks GR, Raikhel NV.
Endosidin2 targets conserved exocyst complex subunit EXO70 to inhibit exocytosis.
Proc Natl Acad Sci U S A. 2015 Nov 25. [Epub ahead of print]
PI: G.K. Muday
Note: This article may be obtained online without charge.
Journal Impact Factor: 9.674
Funding: "US Department of Energy Grant DE-FG02-02ER15295 provided financial support (to N.V.R. and G.R.H.). The National Aeronautics and Space Administration provided financial support with Grant NNX09AK82G (to G.K.M.). Grantová Agentura České Republiky/Czech Science Foundation Project 15-14886S and Ministerstvo Školství, Mládeže a Tělovýchovy České Republiky Project NPUI LO1417 provided support (to V.Z.)."
Boothby TC, Tenlen JR, Smith FW, Wang JR, Patanella KA, Osborne Nishimura E, Tintori SC, Li Q, Jones CD, Yandell M, Messina DN, Glasscock J, Goldstein B.
Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade.
Proc Natl Acad Sci U S A. 2015 Nov 23. [Epub ahead of print]
PI: T.C. Boothby
Journal Impact Factor: 9.674
Funding: "This work was funded by National Science Foundation Grant IOS 1257320 (to B.G.), National Aeronautics and Space Administration Grant 14-14SF_Step2-0019 [NNX15AB44G] (to T.C.B.), National Institute of General Medical Science Grant K12GM000678 (to J.R.T.), and North Carolina Biotechnology Center Grant 2013-MRG-1110 (to C.D.J.), and by contributions from the University of North Carolina at Chapel Hill’s Integrative Program for Biological and Genome Sciences, Carolina Center for Genome Sciences, and Office of the Vice Chancellor for Research."
Govey PM, Kawasawa YI, Donahue HJ.
Mapping the osteocytic cell response to fluid flow using RNA-Seq.
J Biomech. 2015 Nov 5. [Epub ahead of print]
PI: H.J. Donahue
Journal Impact Factor: 2.751
Funding: "This work was supported by 9R01AR068132-15 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health." The PI reports funding by NSBRI.
Hurst VW, Peterson S, Garcia K, Ebert D, Ham D, Amponsah D, Dulchavsky S.
Concept of operations evaluation for using remote-guidance ultrasound for exploration spaceflight.
Aerosp Med Hum Perform. 2015 Dec;86(12):1034-8.
Journal Impact Factor: 0.875
Funding: "The work for this study was performed in the Space Medicine Division at NASA JSC under National Space Biomedical Research Institute contract # L69030 with Wyle."
Aerospace Medicine and Human Performance has published a supplement – "Exercise Countermeasures: The First Decade on ISS," a collaborative effort of the International Counter-measures Working Group. Judith Hayes notes in her introductory article that the principal objective of the supplement is "to document the operational ISS exercise countermeasures system and the associated health outcomes of astronauts and cosmonauts during Expeditions 1-25. . .[the] supplement describes events, records lessons learned, and assesses biomedical results obtained during the first decade of ISS." The articles are available free of charge at http://www.ingentaconnect.com/content/asma/amhp/2015/00000086/a00112s1;jsessionid=81ft2l0bf48q.alice.
The first decade of ISS exercise: Lessons learned on Expeditions 1-25.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A1-A6.
Exercise countermeasure hardware evolution on ISS: The first decade.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A7-A13.
Loehr JA, Guilliams ME, Petersen N, Hirsch N, Kawashima S, Ohshima H.
Physical training for long-duration spaceflight.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A14-A23.
Kozlovskaya IB, Yarmanova EN, Yegorov AD, Stepantsov VI, Fomina EV, Tomilovaskaya ES.
Russian countermeasure systems for adverse effects of microgravity on long-duration ISS flights.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A24-A31.
Yarmanova EN, Kozlovskaya IB, Khimoroda NN, Fomina EV.
Evolution of Russian microgravity countermeasures.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A32-A37.
Sibonga JD, Spector ER, Johnston SL, Tarver WJ.
Evaluating bone loss in ISS astronauts.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A38-A44.
Wood SJ, Paloski WH, Clark JB.
Assessing sensorimotor function following ISS with computerized dynamic posturography.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A45-A53.
Lee SMC, Feiveson AH, Stein S, Stenger MB, Platts SH.
Orthostatic intolerance after ISS and Space Shuttle Missions.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A54-A67.
English KL, Lee SMC, Loehr JA, Ploutz-Snyder RJ, Ploutz-Snyder LL.
Isokinetic strength changes following long-duration spaceflight on the ISS.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A68-A77.
Moore AD Jr, Lynn PA, Feiveson AH.
The first 10 years of aerobic exercise responses to long-duration ISS flights.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A78-A86.
Laughlin MS, Guilliams ME, Nieschwitz BA, Hoellen D.
Functional fitness testing results following long-duration ISS missions.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A87-A91.
Exercise countermeasures on ISS: Summary and future directions.
Aerosp Med Hum Perform. 2015 Dec;86(12, Suppl):A92-A94.
Other papers of interest:
Career perspective: Victor A. Convertino.
Extrem Physiol Med. 2015 Nov 19;4:21.
Note: The author reviews his work with NASA in exercise and physiology research and in acute and chronic physiological responses to varying gravitational environments. This article may be obtained online without charge.
Sathishkumar Y, Krishnaraj C, Rajagopal K, Sen D, Lee YS.
High throughput de novo RNA sequencing elucidates novel responses in Penicillium chrysogenum under microgravity.
Bioprocess Biosyst Eng. 2015 Nov 24. [Epub ahead of print]
Note: ISS results.
Otsuka K, Cornelissen G, Kubo Y, Hyashi M, Yamamoto N, Shibata K, Aiba T, Furukawa S, Ohshima H, Mukai C.
Intrinsic cardiovascular autonomic regulatory system of astronauts exposed long-term to microgravity in space: Observational study.
npj Microgravity. 2015 Nov 30;1:15018.
Note: ISS results. This article may be obtained online without charge.
[Early development under microgravity conditions].
Biofizika. 2015 Sep-Oct;60(5):1024-35. Russian.
Note: Specific space flights or simulation techniques are not mentioned in the English abstract.
Redox interventions to increase exercise performance.
J Physiol. 2015 Nov 20. [Epub ahead of print] Review.
Comments on body mass changes during long-duration spaceflight.
Aerosp Med Hum Perform. 2015 Dec;86(12):1070-1. Comment.
Note: This is a Comment on the article: Zwart SR, Laumius RD, Coen GK, Morgan JLL, Charles JB, Smith SM. Body mass changes during long-duration spaceflight. Aviat Space Environ Med. 2014;85:897-904, which appeared in Current Awareness List #614, 5 Sep 2014.
Parmar P, Perry R, Martin J, Vickers S, Baptista R, Edwards R, McArtor J, Mitchell L, Caruso J.
Net energy costs from resistive exercise done on flywheel-based hardware.
Isokinet Exerc Sci. 2015;23(4):221-7.
Loveman GAM, Seddon FM, Jurd KM, Thacker JC, Fisher AS.
First aid oxygen treatment for decompression illness in the goat after simulated submarine escape.
Aerosp Med Hum Perform. 2015 Dec;86(12):1020-7.
Sarabon N, Rosker J.
Effects of fourteen-day bed rest on trunk stabilizing functions in aging adults.
Biomed Res Int. 2015;2015:309386. Epub 2015 Oct 25.
Note: Bed rest study. This article may be obtained online without charge.
Salanova M, Gambara G, Moriggi M, Vasso M, Ungethuem U, Belavý DL, Felsenberg D, Cerretelli P, Gelfi C, Blottner D.
Vibration mechanosignals superimposed to resistive exercise result in baseline skeletal muscle transcriptome profiles following chronic disuse in bed rest.
Sci Rep. 2015 Nov 25;5:17027.
Note: Bed rest study. This article may be obtained online without charge.
Lomonosova YN, Turtikova OV, Shenkman BS.
Reduced expression of MyHC slow isoform in rat soleus during unloading is accompanied by alterations of endogenous inhibitors of calcineurin/NFAT signaling pathway.
J Muscle Res Cell Motil. 2015 Nov 20. [Epub ahead of print]
Note: Hindlimb unloading study.
Liu SZ, Jemiolo B, Lavin KM, Lester BE, Trappe SW, Trappe TA.
Prostaglandin E2/cyclooxygenase pathway in human skeletal muscle: Influence of muscle fiber type and age.
J Appl Physiol (1985). 2015 Nov 25:jap.00396.2015. [Epub ahead of print]
Zhao Y, Ma X, Wang J, Chen S, Yuan H, Xu A, Hang H, Wu L.
The Roles of p21 and Hus1 in generation and transmission of damage signals stimulated by low-dose alpha-particle irradiation.
Radiat Res. 2015 Nov 24. [Epub ahead of print]
Baulch JE, Geidzinski E, Tran KK, Yu L, Zhou YH, Limoli CL.
Irradiation of primary human gliomas triggers dynamic and aggressive survival responses involving microvesicle signaling.
Environ Mol Mutagen. 2015 Nov 25. [Epub ahead of print]
Barnett-Cowan M, Snow JC, Culham JC.
Contribution of bodily and gravitational orientation cues to face and letter recognition.
Multisens Res. 2015;28(5-6):427-42.
Lacquaniti F, Bosco G, Gravano S, Indovina I, La Scaleia B, Maffei V, Zago M.
Gravity in the brain as a reference for space and time perception.
Multisens Res. 2015;28(5-6):397-426.
Akutsu M, Sugita-Kitajima A, Mikami K, Koizuka I.
Plasticity of the human vestibulo-ocular reflex during off-vertical axis rotation.
Auris Nasus Larynx. 2015 Nov 17. [Epub ahead of print]
Note: A rotating chair was used.
Stoller J, Joseph J, Parodi N, Gardner A.
Are there detrimental effects from proficiency-based training in fundamentals of laparoscopic surgery among novices? An exploration of goal theory.
J Surg Educ. 2015 Nov 16. [Epub ahead of print]
Note: The NASA Task Load Index was used.
Mechanisms of mechanosensing-mechanosensitive channels, function and re-engineering.
Curr Opin Chem Biol. 2015 Nov 20;29:120-7. [Epub ahead of print] Review.
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