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NASA Spaceline Current Awareness List #680 8 January 2016

Status Report From: Spaceline
Posted: Friday, January 8, 2016

Articles deriving from NASA support:

1

Keune JA, Branscum AJ, Iwaniec UT, Turner RT.

Effects of spaceflight on bone microarchitecture in the axial and appendicular skeleton in growing ovariectomized rats.

Sci Rep. 2015 Dec 22;5:18671.

http://www.ncbi.nlm.nih.gov/pubmed/26691062

PI: R.T. Turner

Note: STS-62 results. This article may be obtained online without charge.

Journal Impact Factor: 5.578

Funding: "This work was supported by the National Science Foundation Research Traineeship Program (DGE-0956280) and a grant from the National Aeronautics and Space Administration (NNX12AL24G)."

2

Cannon AE, Salmi ML, Clark G, Roux S.

New insights in plant biology gained from research in space.

Gravit Space Res. 2015 Dec;3(2):3-19. Review.

http://gravitationalandspacebiology.org/index.php/journal/article/view/692/726

PI: S. Roux

Note: ISS results. The article is featured on the cover of Gravitational and Space Research: http://gravitationalandspacebiology.org/index.php/journal. "From the cover: A hypothetical model showing that a gradient of extracellular nucleotides could activate calcium channels, contributing to a calcium differential that is essential for gravity-directed polarization in Ceratopteris richardii spores." This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "Experimental work and support during the preparation of this manuscript was provided by NASA grants NNX13AM54G to SJR and GC, and NNX15AB85A to SJR and MLS."

3

Hammond TG, Allen PL, Birdsall HH.

Validation of assays for reactive oxygen species and glutathione in Saccharomyces cerevisiae during microgravity simulation.

Gravit Space Res. 2015 Dec;3(2):42-53.

http://gravitationalandspacebiology.org/index.php/journal/article/view/701/732

PI: T.G. Hammond

Note: Assay methods were validated for use in future microgravity simulation studies. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "These studies were supported by NASA Grant NNX13AN32G."

4

Parsons-Wingerter P, Hosamani R, Vickerman MB, Bhattacharya S.

Mapping by VESGEN of wing vein phenotype in Drosophila for quantifying adaptations to space environments.

Gravit Space Res. 2015 Dec;3(2):54-64.

http://gravitationalandspacebiology.org/index.php/journal/article/view/693/731

PIs: P. Parsons-Wingerter, S.Bhattacharya

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported by NASA grant NNH09ZTT003N/FSB09PROP-0022 to Sharmila Bhattacharya and NASA Space Life and Physical Sciences Program for Patricia Parsons-Wingerter."

5

Su F, Bhattacharya S, Abdisalaam S, Mukherjee S, Yajima H, Yang Y, Mishra R, Srinivasan K, Ghose S, Chen DJ, Yannone SM, Asaithamby A.

Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway.

Oncotarget. 2015 Dec 18. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26695548

PI: A. Asaithamby, H. Sadek

Note: This article may be obtained online without charge.

Journal Impact Factor: 6.359

Funding: "This work was supported by the National Aeronautics and Space Association grants NNX13AD57G and NNX15AE06G (to A.A.)."

6

Wu Y, Lee SH, Williamson EA, Reinert BL, Cho JH, Xia F, Jaiswal AS, Srinivasan G, Patel B, Brantley A, Zhou D, Shao L, Pathak R, Hauer-Jensen M, Singh S, Kong K, Wu X, Kim HS, Beissbarth T, Gaedcke J, Burma S, Nickoloff JA, Hromas RA.

EEPD1 rescues stressed replication forks and maintains genome stability by promoting end resection and homologous recombination repair.

PLoS Genet. 2015 Dec 18;11(12):e1005675.

http://www.ncbi.nlm.nih.gov/pubmed/26684013

PI: S. Burma

Note: This article may be obtained online without charge.

Journal Impact Factor: 7.528

Funding: "This work was supported by the National Cancer Institute (http://www.cancer.gov/) R01 CA139429 to RAH, R01 CA152367 to SHL, R01 CA163838 to FX, R01 CA188500 to FX, R01 CA140972 to XW, R01 CA102361 to XW, R01 CA122023 to DZ, R01 CA149461 to SB; the National Institute for General Medical Sciences (http://www. nigms.nih.gov/) R01 GM084020 to JAN, R01 GM109645 to RAH, P20 GM109005 to DZ and MHJ; National Aeronautics and Space Administration (http://www.nasa.gov/) NNX13AI13G (SB); the Edward P. Evans Foundation (http://epefoundation.org/) to DZ and MHJ; and the Leukemia and Lymphoma Society (http://www.lls.org/) 6253-13 and 8995-14 to RAH."

7

English KL, Mettler JA, Ellison JB, Mamerow MM, Arentson-Lantz E, Pattarini JM, Ploutz-Snyder R, Sheffield-Moore M, Paddon-Jones D.

Leucine partially protects muscle mass and function during bed rest in middle-aged adults.

Am J Clin Nutr. 2015 Dec 30. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26718415

PI: D. Paddon-Jones

Note: Bed rest study.

Journal Impact Factor: 6.770

Funding: "Supported by National Space Biomedical Research Institute grant NNJ08ZSA002N, NIH R01NR012973 (DP-J), a Texas Space Grant Consortium fellowship (KLE), NIH grant T32HD007539, and in part by the University of Texas Medical Branch (UTMB) Claude D Pepper Older Americans Independence Center, NIH/National Institute on Aging grant P30 AG024832 and grant 1UL1RR029876-01 from the National Center for Research Resources. The study was conducted with the support of UTMB's Institute for Translational Sciences, supported in part by a Clinical and Translational Science Award (UL1TR000071) from the National Center for Advancing Translational Sciences (NIH)."

8

Gadomski BC, Lerner ZF, Browning RC, Easley JT, Palmer RH, Puttlitz CM.

Computational characterization of fracture healing under reduced gravity loading conditions.

J Orthop Res. 2015 Dec 24. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26704186

PI: C.M. Puttlitz

Note: Hindlimb unloading study in sheep using orthopedic fixation plates.

Journal Impact Factor: 2.986

Funding: "This work was supported by the National Aeronautics and Space Administration (NNX11AQ81G)."

9

Grover K, Lin L, Hu M, Muir J, Qin YX.

Spatial distribution and remodeling of elastic modulus of bone in micro-regime as prediction of early stage osteoporosis.

J Biomech. 2015 Dec 3. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26705110

PI: Y.X. Qin

Note: Hindlimb unloading study.

Journal Impact Factor: 2.751

Funding: "This work is kindly supported by the National Institute of Health (R01 AR52379 and R01 AR61821), the US Army Medical Research and Materiel Command (W81 XWH-07-1-0337), and the National Space Biomedical Research Institute through NASA contract NCC 9-58."

10

Lee ML, Howard ME, Horrey WJ, Liang Y, Anderson C, Shreeve MS, O'Brien CS, Czeisler CA.

High risk of near-crash driving events following night-shift work.

Proc Natl Acad Sci U S A. 2015 Dec 22. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26699470

PI: M.L. Lee, NSBRI Postdoctoral Fellowship Program

Note: This article may be obtained online without charge.

Journal Impact Factor: 9.674

Funding: "This study was supported by a grant from the Institute of Breathing and Sleep Research (to M.E.H.); by Liberty Mutual Insurance; National Institutes of Health Award 5T32HL7901-14 (to M.L.L.); National Space Biomedical Research Institute Award PF03002 (to M.L.L.); Department of Homeland Security Federal Emergency Management Agency Assistance to Firefighter Grant EMW-2010-FP-00521 (to C.A.C.); National Heart, Lung and Blood Institute Cooperative Agreement U01-HL111478 (to C.A.C.); National Institute of Occupational Safety and Health Grant R01-OH0103001 (to C.A.C.); National Institute on Aging Grant R01-AG044416 (to C.A.C.); and an endowed professorship provided to Harvard Medical School by Cephalon, Inc. (to C.A.C.)."

11

Cook CA, Tucker A, Shen K, Wyatt SE.

Microarray identifies transcription factors potentially involved in gravitropic signal transduction in Arabidopsis.

Gravit Space Res. 2015 Dec;3(2):20-9.

http://gravitationalandspacebiology.org/index.php/journal/article/view/694/727

PI: S.E. Wyatt

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: No funding cited. PI reports funding under NASA #NNX13AM48G.

______________________________________________________

Other papers of interest:

1

Larina IM, Nichiporuk IA, Veselova OM, Vasilieva GY, Popova IA.

Shifts in metabolism and its regulation under the effect of spaceflight factors.

Human Physiol. 2015 Dec;41(7):689-98. Review.

http://link.springer.com/article/10.1134%2FS0362119715070105

Note: Cosmos biosatellite (782, 936, 1129, 1667, and 2044) results. Original Russian text: I.M. Larina, I.A. Nichiporuk, O.M. Veselova, G.Yu. Vasilieva, I.A. Popova, Aviakosmicheskaya i Ekologicheskaya Meditsina. 2013;47(1):2130. The Russian article was cited in Current Awareness List #590, 8 Aug 2013.

2

Onofri S, de Vera JP, Zucconi L, Selbmann L, Scalzi G, Venkateswaran KJ, Rabbow E, de la Torre R, Horneck G.

Survival of Antarctic cryptoendolithic fungi in simulated Martian conditions on board the International Space Station.

Astrobiology. 2015 Dec;15(12):1052-9.

http://www.ncbi.nlm.nih.gov/pubmed/26684504

Note: ISS results.

3

Narici L, Berger T, Matthi D, Reitz G.

Radiation measurements performed with active detectors relevant for human space exploration.

Front Oncol. 2015 Dec 8;5:273.

http://www.ncbi.nlm.nih.gov/pubmed/26697408

Note: ISS results. This article may be obtained online without charge.

4

Mao RJ, Qi ZH, Han RL, Liu FH, Liu Y, Liang ZS.

Spaceflight-induced variation on biological traits and effective components of Cassia obtusifolia.

Zhongguo Zhong Yao Za Zhi. 2015 Jul;40(13):2571-5.

http://www.ncbi.nlm.nih.gov/pubmed/26697680

Note: Shenzhou 8 results.

5

Schler O, Hemmersbach R, Bhmer M.

A bird's-eye view of molecular changes in plant gravitropism using omics techniques.

Front Plant Sci. 2015 Dec 24;6:1176. Review.

http://www.frontiersin.org/Journal/Abstract.aspx?s=907&name=plant_physiology&ART_DOI=10.3389/fpls.2015.01176

Note: The review focuses on spaceflight and simulated microgravity studies. This article may be obtained online without charge.

6

Shahim P, Arnell P, Kvarnstrm A, Rosn A, Bremell D, Hagberg L, Blennow K, Zetterberg H.

Cerebrospinal fluid markers of central nervous system injury in decompression illness - A case-controlled pilot study.

Diving Hyperb Med. 2015 Dec;45(4):240-3.

http://www.ncbi.nlm.nih.gov/pubmed/26687311

7

Kang H, Fan Y, Zhao P, Ren C, Wang Z, Deng X.

Regional specific modulation of the glycocalyx and smooth muscle cell contractile apparatus in conduit arteries of tail-suspended rats.

J Appl Physiol (1985). 2015 Dec 17:jap.00245.2015. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26679611

Note: Hindlimb unloading study.

8

Peng L, Ran HH, Zhang Y, Zhao Y, Fan YY, Peng L, Zhang R, Cao F.

NADPH oxidase accounts for changes in cerebrovascular redox status in hindlimb unweighting rats.

Biomed Environ Sci. 2015 Nov;28(11):799-807.

http://www.ncbi.nlm.nih.gov/pubmed/26695358

Note: Hindlimb unloading study. This article may be obtained online without charge.

9

Dakin CJ, Heroux ME, Luu BL, Inglis JT, Blouin JS.

Vestibular contribution to balance control in the medial gastrocnemius and soleus.

J Neurophysiol. 2015 Dec 16:jn.00512.2015. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26683068

10

Fu A, Wang C, Qi H, Li F, Wang Z, He F, Zhou P, Chen S, Ming D.

Electromyography-based analysis of human upper limbs during 45-day head-down bed-rest.

Acta Astronaut. 2016 Mar-Apr;120:260-9.

http://www.sciencedirect.com/science/article/pii/S0094576515004415

Note: Bed rest study.

11

Germinario E, Bondi M, Cencetti F, Donati C, Nocella M, Colombini B, Betto R, Bruni P, Bagni MA, Danieli-Betto D.

S1P3 receptor influences key physiological properties of fast-twitch extensor digitorum longus muscle.

J Appl Physiol (1985). 2015 Dec 30. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26718782

12

Nagano K.

Alteration of cathepsin-D expression in atrophied muscles and apoptotic myofibers by hindlimb unloading in a low-temperature environment.

J Phys Ther Sci. 2015 Nov;27(11):3585-91. Epub 2015 Nov 30.

http://www.ncbi.nlm.nih.gov/pubmed/26696743

Note: Hindlimb unloading study. This article may be obtained online without charge.

13

Saxena S, Shukla D, Bansal A.

Expression of monocarboxylate transporter isoforms in rat skeletal muscle under hypoxic preconditioning and endurance training.

High Alt Med Biol. 2015 Dec 30. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26716978

14

Tanaka S, Obatake T, Hoshino K, Nakagawa T.

Influence of exercise intensity on atrophied quadriceps muscle in the rat.

J Phys Ther Sci. 2015 Nov;27(11):3445-50. Epub 2015 Nov 30.

http://www.ncbi.nlm.nih.gov/pubmed/26696716

Note: Hindlimb unloading study. This article may be obtained online without charge.

15

Gmez-Bruton A, Gonzlez-Agero A, Gmez-Cabello A, Matute-Llorente A, Casajs JA, Vicente-Rodriguez G.

Swimming and bone: Is low bone mass due to hypogravity alone or does other physical activity influence it?

Osteoporos Int. 2015 Dec 22. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26694592

Note: Swimming is presented as an analog for hypogravity.

16

Hu Z, Wang Y, Sun Z, Wang H, Zhou H, Zhang L, Zhang S, Cao X.

miRNA-132-3p inhibits osteoblast differentiation by targeting Ep300 in simulated microgravity.

Sci Rep. 2015 Dec 21;5:18655.

http://www.ncbi.nlm.nih.gov/pubmed/26686902

Note: Hindlimb unloading study. This article may be obtained online without charge.

17

Kakuris KK, Yaroshenko YN, Charapakhin KP, Neofitov NH.

Chronic head-down-tilt sleeping as physiological regulator of bone remodelling during diminished muscular activity in humans.

Clin Physiol Funct Imaging. 2015 Dec 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26711194

Note: Head-down tilt sleeping position was used.

18

Wu XT, Sun LW, Qi HY, Shi H, Fan YB.

The bio-response of osteocytes and its regulation on osteoblasts under vibration.

Cell Biol Int. 2015 Dec 30. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26715381

19

Held KD, Woloschak GE.

NCRP Program Area Committee 1: Basic criteria, epidemiology, radiobiology and risk.

Health Phys. 2016 Feb;110(2):98-100.

http://www.ncbi.nlm.nih.gov/pubmed/26717156

20

Dauer LT, Ainsbury EA, Dynlacht J, Hoel D, Klein BE, Mayer D, Prescott CR, Thornton RH, Vano E, Woloschak GE, Flannery CM, Goldstein LE, Hamada N, Tran PK, Grissom MP, Blakely EA.

Status of NCRP Scientific Committee 1-23 commentary on guidance on radiation dose limits for the lens of the eye.

Health Phys. 2016 Feb;110(2):182-4.

http://www.ncbi.nlm.nih.gov/pubmed/26717175

21

Velalopoulou A, Tyagi S, Pietrofesa RA, Arguiri E, Christofidou-Solomidou M.

The flaxseed-derived lignan phenolic secoisolariciresinol diglucoside (SDG) protects non-malignant lung cells from radiation damage.

Int J Mol Sci. 2015 Dec 22;17(1).

http://www.ncbi.nlm.nih.gov/pubmed/26703588

Note: This article may be obtained online without charge.

22

Bury N, Bock O.

Role of gravitational versus egocentric cues for human spatial orientation.

Exp Brain Res. 2015 Dec 26. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26706040

23

Fraser LE, Makooie B, Harris LR.

The subjective visual vertical and the subjective haptic vertical access different gravity estimates.

PLoS One. 2015 Dec 30;10(12):e0145528.

http://www.ncbi.nlm.nih.gov/pubmed/26716835

Note: This article may be obtained online without charge.

24

Lim J, Kwok K.

The effects of varying break length on attention and time on task.

Hum Factors. 2015 Dec 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26715686

25

Fadaee SB, Migliaccio AA.

The effect of retinal image error update rate on human vestibulo-ocular reflex gain adaptation.

Exp Brain Res. 2015 Dec 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26715411

26

Kaski D, Quadir S, Nigmatullina Y, Malhotra PA, Bronstein AM, Seemungal BM.

Temporoparietal encoding of space and time during vestibular-guided orientation.

Brain. 2015 Dec 30. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26719385

Note: This article may be obtained online without charge.

27

Arnaldi KM, Smith G, Thropp JE.

Human behavior during spaceflight - Evidence from an analog environment.

J Aviat/Aerospace Educ Res. 2015 Fall;25(1):26-71.

http://commons.erau.edu/jaaer/vol25/iss1/2/

Note: A small recreational vehicle (RV) was configured to replicate an artificial orbital 2-person habitat (AOH). This article may be obtained online without charge.

28

Berkovich YA, Krivobok NM, Krivobok AS, Smolyanina SO.

Advanced nutrient root feeding system for conveyer-type cylindrical plant growth facilities for microgravity.

Life Sci Space Res. 2015 Dec 21. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552415001005

29

Kircher S, Schopfer P.

Priming and positioning of lateral roots in Arabidopsis. An approach for an integrating concept.

J Exp Bot. 2015 Dec 27. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26712828

Note: This article may be obtained online without charge.

30

Wei Z, Li J.

Brassinosteroids regulate root growth, development, and symbiosis.

Mol Plant. 2015 Dec 15. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26700030

31

Zhang L, Wang T, Zheng F, Ma L, Li J.

Effects of the ionic liquid 1-hexyl-3-methylimidazolium bromide on root gravitropism in arabidopsis seedlings.

Ecotoxicol Environ Saf. 2015 Dec 10;125:107-15. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26685782

32

Fager SK, Burnfield JM.

Speech recognition for environmental control: Effect of microphone type, dysarthria, and severity on recognition results.

Assist Technol. 2015 Winter;27(4):199-207.

http://www.ncbi.nlm.nih.gov/pubmed/26691559

Note: The NASA Task Load Index was used.

33

Schulman AR, Thompson CC, Ryou M.

EUS-guided portal pressure measurement using a digital pressure wire with real-time remote display: A novel, minimally invasive technique for direct measurement in an animal model.

Gastrointest Endosc. 2015 Dec 9. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26684600

Note: The NASA Task Load Index was used.

// end //

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