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NASA Spaceline Current Awareness List #687 26 February 2016

Status Report From: Spaceline
Posted: Friday, February 26, 2016

Papers deriving from NASA support:

 

1

Globus RK, Morey-Holton E.

Hindlimb unloading: Rodent analog for microgravity.

J Appl Physiol (1985). 2016 Feb 11:jap.00997.2015. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/26869711

PI: R.K. Globus

Note: Hindlimb unloading studies are reviewed.

Journal Impact Factor: 3.056

Funding: "We also are grateful for research support from National Space Biomedical Research Institute (through NCC 9-58) and NASA’s HRP and Space Biology programs."

 

2

Hargens AR, Vico L.

Long-duration bed rest as an analog to microgravity.

J Appl Physiol (1985). 2016 Feb 18:jap.00935.2015. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/26893033

PI: A.R. Hargens

Note: Bed rest studies are reviewed.

Journal Impact Factor: 3.056

Funding: "L Vico is supported in part by CNES (Centre National d’Etudes Spatiales) and the European Space Agency. A Hargens is supported in part by NASA grants NNX14AP25G, NNX13AM89G, NNX13AJ12G, NNX12AL66G, NNX10AM18G, NNX09AP11G, NNJ04HF71G and NAG 9-1425."

 

3

Pongkitwitoon S, Weinheimer-Haus EM, Koh TJ, Judex S.

Low-intensity vibrations accelerate proliferation and alter macrophage phenotype in vitro.

J Biomech. 2016 Feb 8. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26897645

PI: S. Judex

Journal Impact Factor: 2.751

Funding: "We are grateful to the U.S. Department of Defense (W81XWH-14-1-0281) and the National Aeronautics and Space Administration (NNX12AL25G) for supporting this work."

 

4

Romero-Mangado J, Nordlund D, Soberon F, Deane G, Maughan K, Sainio S, Singh G, Daniels S, Saunders IT, Loftus D, Meyyappan M, Koehne J, Gandhiraman RP.

Morphological and chemical changes of aerosolized E. coli treated with a dielectric barrier discharge.

Biointerphases. 2016 Mar 12;11(1):011009.

http://www.ncbi.nlm.nih.gov/pubmed/26872580

Note: This article may be obtained online without charge at http://scitation.aip.org/content/avs/journal/bip/11/1/10.1116/1.4941367

Journal Impact Factor: 2.677

Funding: "J. Romero-Mangado is a Science and Technology Corporation employee subcontracted to work at NASA Ames Research Center. Ian T. Saunders was a student intern from Norfolk State University. Use of the Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, is supported by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences under Contract No. DE-AC02-76SF00515."  D. Loftus, M. Meyyappan, and J. Koehne are at NASA Ames Research Center.

 

5

Taibbi G, Cromwell RL, Zanello SB, Yarbough PO, Ploutz-Snyder RJ, Godley BF, Vizzeri G.

Ocular outcomes comparison between 14- and 70-day head-down-tilt bed rest.

Invest Ophthalmol Vis Sci. 2016 Feb 1;57(2):495-501.

http://www.ncbi.nlm.nih.gov/pubmed/26868753 

PI: R.L. Cromwell, NASA Flight Analogs Project

Note: Bed rest study. This article may be obtained online without charge.

Journal Impact Factor: 3.404

Funding: "Supported by NASA Flight Analogs Project 516724.03.04.01; National Institutes of Health/National Center for Research Resources 1UL1RR029876-01. Supported in part by an unrestricted grant from Research to Prevent Blindness (RPB) to the University of Texas Medical Branch, Galveston, Texas, United States."

 

6

Mader TH, Gibson CR, Hart SF, Lee AG.

Asymmetric papilledema in idiopathic intracranial hypertension: Comment.

J Neuroophthalmol. 2016 Mar;36(1):111-2.

http://www.ncbi.nlm.nih.gov/pubmed/26885711

Note: This paper is a comment on the article by Bidot S, et al., below.

Journal Impact Factor: 1.950

Funding: No funding cited; S.F. Hart is at NASA Johnson Space Center.

 

Bidot S, Bruce BB, Saindane AM, Newman NJ, Biousse V.

Asymmetric papilledema in idiopathic intracranial hypertension.

J Neuroophthalmol. 2015 Mar;35(1):31-6.

http://www.ncbi.nlm.nih.gov/pubmed/25494197

Note: This article may be obtained online without charge.

 

7

Holt JA, Macias BR, Schneider SM, Watenpaugh DE, Lee SM, Chang DG, Hargens AR.

WISE 2005: Aerobic and resistive countermeasures prevent paraspinal muscle deconditioning during 60-days bed rest in women.

J Appl Physiol (1985). 2016 Feb 18:jap.00532.2015. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26893030

PI: A.R. Hargens

Note: Bed rest study.

Journal Impact Factor: 3.056

Funding: "The WISE-2005 study was sponsored by the European Space Agency, the US National Aeronautics and Space Administration (NASA), the Canadian Space Agency, and the French "Centre National d’Etudes Spatiales," which was the "Promoteur" of the study according to French law. The study was conducted at Medes Institute for Space Physiology and Medicine in Toulouse, France. This work was supported by NASA Grant NNJ04HF71G to A. R. Hargens."

 

8

Tahimic CG, Long RK, Kubota T, Sun MY, Elalieh H, Fong C, Menendez AT, Wang Y, Vilardaga JP, Bikle DD.

Regulation of ligand and shear stress-induced insulin-like growth factor 1 (IGF1) signaling by the integrin pathway.

J Biol Chem. 2016 Feb 10. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26865633

PIs: R.K. Long and T. Kubota, NSBRI Postdoctoral Fellowship Program

Note: This article may be obtained online without charge.

Journal Impact Factor: 4.573

Funding: "This work was supported by the National Institutes of Health (NIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) (RO1 AR055924 to DDB) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDKK) (R01 DK087688 and R01DK102495 to J-PV). RKL and TK were supported by postdoctoral fellowship awards from the National Space Biomedical Research Institute (NSBRI, NASA NCC 9-58)."

 

9

Norbury JW, Schimmerling W, Slaba TC, Azzam E, Badavi FF, Baiocco G, Benton E, Bindi V, Blakely EA, Blattnig SR, Boothman DA, Borak TB, Britten RA, Curtis S, Dingfelder M, Durante M, Dynan W, Eisch AJ, Robin Elgart S, Goodhead DT, Guida PM, Heilbronn LH, Hellweg CE, Huff JL, Kronenberg A, La Tessa C, Lowenstein D, Miller J, Morita T, Narici L, Nelson GA, Norman RB, Ottolenghi A, Patel ZS, Reitz G, Rusek A, Schreurs A-S, Scott-Carnell LA, Semones E, Shay JW, Shurshakov VA, Sihver L, Simonsen LC, Story M, Turker MS, Uchihori Y, Williams J, Zeitlin CJ.

Galactic cosmic ray simulation at the NASA Space Radiation Laboratory.

Life Sci Space Res. 2016 Feb 17. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552416300013

PI: J.W. Norbury

Note: Opinion/Position paper.

Journal Impact Factor: 1.183

Funding: "Funding for this study was provided by the NASA Human Research Program Space Radiation Element."

 

10

Hadley MM, Davis LK, Jewell JS, Miller VD, Britten RA.

Exposure to mission-relevant doses of 1 GeV/n (48)Ti particles impairs attentional set-shifting performance in retired breeder rats.

Radiat Res. 2016 Jan;185(1):13-9. Epub 2015 Dec 31.

http://www.ncbi.nlm.nih.gov/pubmed/26720801

PI: R.A. Britten

Journal Impact Factor: 2.911

Funding: "This work was funded by NASA grant nos. NNX11AC56G and NNX14AE73G."

 

 

Note: The following two articles comment on Shelhamer M. A call for research to assess and promote functional resilience in astronaut crews. J Appl Physiol (1985). 2016 Feb 15:120(4):471-2. http://www.ncbi.nlm.nih.gov/pubmed/26472875. The original article was cited in Current Awareness List #670 on 23 October 2015.

 

11

Etheridge T, Szewczyk NJ, Zuo L, Chuang CC, Liu Z, Ward AT, Dier NL, Rotarius TR, Lalande S, Zhang X, Zhang M, Li G, Dong L, Gao F.

Commentaries on Viewpoint: A call for research to assess and promote functional resilience in astronaut crews.

J Appl Physiol (1985). 2016 Feb 15;120(4):473-4.

http://www.ncbi.nlm.nih.gov/pubmed/26879659

Note: Non-NASA authors.

 

12

Shelhamer M.

Last word on Viewpoint: A call for research to assess and promote functional resilience in astronaut crews.

J Appl Physiol (1985). 2016 Feb 15;120(4):475.

http://www.ncbi.nlm.nih.gov/pubmed/26879660

Journal Impact Factor: 3.056

Funding: No funding cited. M. Shelhamer is at NASA Johnson Space Center.

______________________________________________________

 

Other papers of interest:

 

1

Islamov RR, Gusev ОА, Tanabe A, Terada M, Tyapkina OV, Petrov KA, Rizvanov АА, Kozlovskaya IB, Nikolskiy EE, Grigorjev AI.

Full-genome study of gene expression in lumbar spinal cord of mice after 30-day space flight on Bion-M1 biosatellite.

Acta Astronaut. 2016 May;122:231-6.

http://www.sciencedirect.com/science/article/pii/S0094576515301508

Note: Bion-M1 results.

 

2

Watenpaugh DE.

Analogs of microgravity: Head-down tilt and water immersion.

J Appl Physiol (1985). 2016 Feb 11:jap.00986.2015. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/26869710

Note: Bed rest and water immersion studies are discussed.

 

3

Wrigley A.

Recent changes in hypoxia training at the Royal Air Force Centre of Aviation Medicine.

J R Nav Med Serv. 2015;101(2):186-7.

http://www.ncbi.nlm.nih.gov/pubmed/26867422

Note: From the abstract: "This article describes the new system for hypoxia training known as Scenario-Based Hypoxia Training (SBHT), which involves the subject sitting in an aircraft simulator and wearing a mask linked by hose to a Reduced Oxygen Breathing Device (ROBD)."

 

4

Zhao T, Tang X, Umeshappa CS, Ma H, Gao H, Deng Y, Freywald A, Xiang J.

Simulated microgravity promotes cell apoptosis through suppressing Uev1A/TICAM/TRAF/NF-kappaB-regulated anti-apoptosis and p53/PCNA- and ATM/ATR-Chk1/2-Controlled DNA-damage response pathways.

J Cell Biochem. 2016 Feb 16. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26887372

Note: A random positioning machine was used.

 

5

Carter R 3rd, Hinojosa-Laborde C, Convertino VA.

Variability in integration of mechanisms associated with high tolerance to progressive reductions in central blood volume: The compensatory reserve.

Physiol Rep. 2016 Feb;4(4).

http://www.ncbi.nlm.nih.gov/pubmed/26884477

Note: This article may be obtained online without charge.

 

6

Sibony PA, Kupersmith MJ, Feldon SE, Wang JK, Garvin M.

Retinal and choroidal folds in papilledema.

Invest Ophthalmol Vis Sci. 2015 Sep;56(10):5670-80.

http://www.ncbi.nlm.nih.gov/pubmed/26335066

Note: See citations #7 and #8 for Comments. This article may be obtained online without charge.

 

7

Mader TH, Gibson CR, Lee AG.

Choroidal folds in astronauts.

Invest Ophthalmol Vis Sci. 2016 Feb 1;57(2):592.

http://www.ncbi.nlm.nih.gov/pubmed/26886892

Note: Comment on citation #6. This article may be obtained online without charge.

 

8

Sibony PA, Kupersmith MJ, Feldon SE, Kardon R.

Author response: choroidal folds in astronauts.

Invest Ophthalmol Vis Sci. 2016 Feb 1;57(2):593.

http://www.ncbi.nlm.nih.gov/pubmed/26886893

Note: Comment on citation #7. This article may be obtained online without charge.

 

9

Baker JM, Parise G.

Skeletal muscle erythropoietin expression is responsive to hypoxia and exercise.

Med Sci Sports Exerc. 2016 Feb 16. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26885637

 

10

Kuswanto W, Burzyn D, Panduro M, Wang KK, Jang YC, Wagers AJ, Benoist C, Mathis D.

Poor repair of skeletal muscle in aging mice reflects a defect in local, interleukin-33-dependent accumulation of regulatory T cells.

Immunity. 2016 Feb 16;44(2):355-67. Epub 2016 Feb 9.

http://www.ncbi.nlm.nih.gov/pubmed/26872699

 

11

Logan SM, Tessier SN, Tye J, Storey KB.

Response of the JAK-STAT pathway to mammalian hibernation in 13-lined ground squirrel striated muscle.

Mol Cell Biochem. 2016 Feb 17. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26885984

 

12

Zhang D, Hu M, Chu T, Lin L, Wang J, Li X, Ke HZ, Qin YX.

Sclerostin antibody prevented progressive bone loss in combined ovariectomized and concurrent functional disuse.

Bone. 2016 Feb 8. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26868528

Note: Hindlimb unloading study.

 

13

Zennou-Azogui Y, Catz N, Xerri CA.

Hypergravity within a critical period impacts on the maturation of somatosensory cortical maps and their potential for use-dependent plasticity in the adult.

J Neurophysiol. 2016 Feb 17:jn.00900.2015. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26888103

Note: Centrifugation was used.

 

14

Ieraci A, Mallei A, Popoli M.

Social isolation stress induces anxious-depressive-like behavior and alterations of neuroplasticity-related genes in adult male mice.

Neural Plast. 2016;2016:6212983. Epub 2016 Jan 6.

http://www.ncbi.nlm.nih.gov/pubmed/26881124

Note: Tail suspension was used. This article may be obtained online without charge.

 

15

Kayama T, Mori M, Ito Y, Matsushima T, Nakamichi R, Suzuki H, Ichinose S, Saito M, Marumo K, Asahara H.

Gtf2ird1-dependent Mohawk (Mkx) expression regulates mechanosensing properties of tendon.

Mol Cell Biol. 2016 Feb 16. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26884464

Note: This article may be obtained online without charge.

 

16

Rys JP, Monteiro DA, Alliston T.

Mechanobiology of TGFβ signaling in the skeleton.

Matrix Biol. 2016 Feb 12. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/26877077

 

 

 

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