NASA Spaceline Current Awareness List #691 25 March 2016

Status Report From: Spaceline
Posted: Friday, March 25, 2016

Editor's note: NASA's various life sciences programs have prepared the SPACELINE Current Awareness updates since 1999 covering all aspects of space life science, gravitational biology, space medicine, and human factors. NASA does not maintain a website - nor does it have an  archive of this resource online. However, SpaceRef does have a complete archive of SPACELINE updates all the way back to 1999 that can be accessed here:

Papers deriving from NASA support:



Ade CJ, Broxterman RM, Craig JC, Schlup SJ, Wilcox SL, Warren S, Kuehl P, Gude D, Jia C, Barstow TJ.

Prediction of lunar- and Martian-based intra- and site-to-site task performance.

Aerosp Med Hum Perform. 2016 Apr;87(4):367-74.

PI: T.J. Barstow

Note: From the Introduction: ". . . the aim of the present study was to investigate the feasibility of determining the physiological parameters associated with the ability to complete simulated exploration type tasks at metabolic rates which might be expected for intra- and site-to-site lunar and Martian ambulation based on the use of current EVA suit technology."

Journal Impact Factor: 0.875

Funding: "This study was supported by the National Aeronautics and Space Administration (NASA) research grant NNX10AK60G awarded to T. J. Barstow. R. M. Broxterman was supported by NASA EPSCOR grant KS-NNX11AM05A."



Raber J, Weber S, Kronenberg A, Turker MS.

Sex- and dose-dependent effects of calcium ion irradiation on behavioral performance of B6D2F1 mice during contextual fear conditioning training.

Life Sci Space Res. 2016 Mar 22. [Article in Press]

PIs: J. Raber, A. Kronenberg, M.S. Turker

Journal Impact Factor: 1.183

Funding: "This work was supported by NASA grants NNJ05HE63G, NNJ12ZSA001N, NNX14AC97G, and NNJ12HB88I."



Rouchka EC, Flight RM, Fasciotto BH, Estrada R, Eaton JW, Patibandla PK, Waigel SJ, Li D, Kirtley JK, Sethu P, Keynton RS.

Transcriptional profile of immediate response to ionizing radiation exposure.

Genom Data. 2016 Mar;7:82-5.

Note: One of the goals of the study was to develop a test to identify biomarkers for radiation exposure that would be used on long-duration space flights to detect astronaut exposure to radiation. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "Funding was provided by the National Aeronautics and Space Administration (NASA) contract NNX10AJ36G (BHF, ECR, JK, JWE, PKP, PS, RE and RSK); the National Institutes of Health (NIH) grants P20RR016481 (DL, ECR, RMF and SJW), 3P20RR016481-09S1 (ECR, RMF and SJW), and P20GM103436 (ECR and SJW)."



Other papers of interest:



Satoh K, Yamazaki T, Nakayama T, Umeda Y, Alshahni MM, Makimura M, Makimura K.

Characterization of fungi isolated from the equipment used in the International Space Station or Space Shuttle.

Microbiol Immunol. 2016 Mar 11. [Epub ahead of print]

Note: ISS and Shuttle results.



Nuoc TN, Kim S, Ahn SH, Lee JS, Park BJ, Lee TH.

The analysis of antioxidant expression during muscle atrophy induced by hindlimb suspension in mice.

J Physiol Sci. 2016 Mar 12. [Epub ahead of print]

Note: Hindlimb unloading study. This article may be obtained online without charge.



Krüger M, Kötter S.

Titin, a central mediator for hypertrophic signaling, exercise-induced mechanosignaling and skeletal muscle remodeling.

Front Physiol. 2016 Mar 1;7:76. Review.

Note: This article may be obtained online without charge.



Duffy RM, Sun Y, Feinberg AW.

Understanding the role of ECM protein composition and geometric micropatterning for engineering human skeletal muscle.

Ann Biomed Eng. 2016 Mar 16. [Epub ahead of print]



Karsenty G, Olson EN.

Bone and muscle endocrine functions: Unexpected paradigms of inter-organ communication.

Cell. 2016 Mar 10;164(6):1248-56. Review.



Yu HS, Kim JJ, Kim HW, Lewis MP, Wall I.

Impact of mechanical stretch on the cell behaviors of bone and surrounding tissues.

J Tissue Eng. 2016;7:1-24. Review. Epub 2016 Feb 18.

Note: This article may be obtained online without charge.



Wang J-Q, Qi R-R, Pan L-L, Zhou W, Zhang L-L, Cai Y-L.

Motion sickness and resting energy expenditure in Chinese male adults.

Aerosp Med Hum Perform. 2016 Apr;87(4):360-6.



Wang H, Sun Z, Wang Y, Hu Z, Zhou H, Zhang L, Hong B, Zhang S, Cao X.

miR-33-5p, a novel mechano-sensitive microRNA promotes osteoblast differentiation by targeting Hmga2.

Sci Rep. 2016 Mar 16;6:23170.

Note: Clinorotation was used. This article may be obtained online without charge.



Lecomte JF.

Understanding existing exposure situations.

Ann ICRP. 2016 Mar 14. [Epub ahead of print]

Note: From p. 4: "This paper endeavours to demonstrate the application of the system of radiological protection to existing exposure situations, keeping in mind that the role of ICRP is to develop principles and recommendations, and not regulation." The International Commission on Radiological Protection (ICRP) considers exposure to cosmic radiation during spaceflight as an existing exposure situation. This article may be obtained online without charge.



Lackey SJ, Salcedo JN, Szalma JL, Hancock PA.

The stress and workload of virtual reality training: The effects of presence, immersion and flow.

Ergonomics. 2016 Mar 15:1-13. [Epub ahead of print]



Johnston JD, Ordovás JM, Scheer FA, Turek FW.

Circadian rhythms, metabolism, and chrononutrition in rodents and humans.

Adv Nutr. 2016 Mar;7(2):399-406. Review.



Anglin KM, Kring JP.

Lessons from a space analog on adaptation for long-duration exploration missions.

Aerosp Med Hum Perform. 2016 Apr;87(4):406-10.

Note: Results are from the NASA Extreme Environment Mission Operations (NEEMO) 20 mission in July 2015.



Deng S, Xie B, Liu H.

The recycle of water and nitrogen from urine in bioregenerative life support system.

Acta Astronaut. 2016 Jun-Jul;123:86-90.

Note: The study was conducted in the Lunar Palace 1 BLSS.



Yamamoto K, Sakamoto H, Momonoki YS.

Altered expression of acetylcholinesterase gene in rice results in enhancement or suppression of shoot gravitropism.

Plant Signal Behav. 2016 Mar 16. [Epub ahead of print]



Rowson D, Knight MM, Screen HR.

Zonal variation in primary cilia elongation correlates with localised biomechanical degradation in stress deprived tendon.

J Orthop Res. 2016 Mar 11. [Epub ahead of print]



Frizziero A, Salamanna F, Della Bella E, Vittadini F, Gasparre G, Nicoli Aldini N, Masiero S, Fini M.

The role of detraining in tendon mechanobiology.

Front Aging Neurosci. 2016 Feb 29;8:43. Review.

Note: This article may be obtained online without charge.



Bitterman N, Bonen A.

Design and human factors of therapeutic hyperbaric chambers.

Aerosp Med Hum Perform. 2016 Apr;87(4):397-405.



Ma M, Fallavollita P, Habert S, Weidert S, Navab N.

Device- and system-independent personal touchless user interface for operating rooms: One personal UI to control all displays in an operating room.

Int J Comput Assist Radiol Surg. 2016 Mar 16. [Epub ahead of print]

Note: The NASA Task Load Index was used. This article may be obtained online without charge



Isenberg SL, Carter MD, Crow BS, Graham LA, Johnson D, Beninato N, Steele K, Thomas JD, Johnson RC.

Quantification of hydrazine in human urine by HPLC-MS-MS.

J Anal Toxicol. 2016 Mar 13. [Epub ahead of print]



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