SpaceRef

SpaceRef


NASA SPACELINE Current Awareness List #695 22 April 2016 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, April 22, 2016

 

Editor's note: NASA's various life sciences programs have prepared the SPACELINE Current Awareness updates since 1999 covering all aspects of space life science, gravitational biology, space medicine, and human factors. NASA does not maintain a website - nor does it have an archive of this resource online. However, SpaceRef does have a complete archive of SPACELINE updates all the way back to 1999
that can be accessed here: http://www.spaceref.com/news/mission.html?mid=188&pag

 

Papers deriving from NASA support:

 

1

Bloomfield SA, Martinez DA, Boudreaux RD, Mantri AV.

Microgravity stress: Bone and connective tissue.

Compr Physiol. 2016 Mar 15;6(2):645-86. Review.

http://www.ncbi.nlm.nih.gov/pubmed/27065165

PI: S.A. Bloomfield

Note: Results from Skylab, Mir, and the ISS are discussed. This article may be obtained online without charge.

Journal Impact Factor: 4.739

Funding: "S. Bloomfield gratefully acknowledges support from the National Space Biomedical Research Institute and NASA’s Space Biology and Human Research Programs. R. Boudreaux and A. Mantri were supported as Space Life Science Predoctoral Fellows by the National Space Biomedical Research Institute."

 

2

Almeida-Porada G, Atala A, Porada CD.

In utero stem cell transplantation and gene therapy: Rationale, history, and recent advances toward clinical application.

Mol Ther Methods Clin Dev. 2016 Mar 30;5:16020.

http://www.ncbi.nlm.nih.gov/pubmed/27069953

PI: C.D. Porada

Note: This article may be obtained online without charge.

Journal Impact Factor: 6.227

Funding: "The authors gratefully acknowledge support from grants R01-HL097623 and R21-HL117704 from National Institutes of Health (NIH), grant NNX13AB67G from National Aeronautics and Space Administration (NASA), the Intramural Pilot Program of Wake Forest School of Medicine, and Wake Forest University Health Sciences Translational Science Institute 20667 Clinical Pilot Award."

 

3

Lawler JM, Rodriguez DA, Hord JM.

Mitochondria in the middle: Exercise preconditioning protection of striated muscle.

J Physiol. 2016 Apr 6. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/27060608

PI: J.M. Lawlor

Journal Impact Factor: 5.037

Funding: "Support has been provided by grants to J.M.L. from the National Aeronautics and Space Administration (NASA; NNX13AE45G), National Institutes of Health (NIH; AR054084), National Science Foundation (NSF; 055185F), American Heart Association (AHA; 0855158F), and the Huffines Institute at Texas A&M University. J.M.H. is funded through the Strategic Research Award from the College of Education and Human Development (CEHD)."

 

4

Grygoryev D, Gauny S, Lasarev M, Ohlrich A, Kronenberg A, Turker MS.

Charged particle mutagenesis at low dose and fluence in mouse splenic T cells.

Mutat Res. 2016 Mar 29. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27055360

PI: M.S. Turker

Journal Impact Factor: 3.68

Funding: "This work was supported by NASA grants NNX10AC12G and NNX14AC97G."

 

5

Zeitlin C, La Tessa C.

The role of nuclear fragmentation in particle therapy and space radiation protection.

Front Oncol. 2016 Mar 29;6:65.

http://www.ncbi.nlm.nih.gov/pubmed/27065350

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported at Lockheed Martin by the NASA Health and Human Performance Contract NNJ15HK11B, and at the Brookhaven National Laboratory under NASA contract NNJ07HE781 and the U.S. Department of Energy contract DE-AC-2-98CH10886."

______________________________________________________

 

Other papers of interest:

 

1

Arbeille P, Provost R, Zuj K.

Carotid and femoral artery intima-media thickness during 6 months of spaceflight.

Aerosp Med Hum Perform. 2016 May;87(5):449-53.

http://www.ingentaconnect.com/content/asma/amhp/2016/00000087/00000005/art00005

Note: ISS results.

 

2

Staples JF.

Metabolic flexibility: Hibernation, torpor, and estivation.

Compr Physiol. 2016 Mar 15;6(2):737-71.

http://www.ncbi.nlm.nih.gov/pubmed/27065167

 

3

Lautridou J, Pichereau V, Artigaud S, Buzzacott P, Wang Q, Bernay B, Driad S, Mazur A, Lambrechts K, Théron M, Guerrero F.

Effect of simulated air dive and decompression sickness on the plasma proteome of rats.

Proteomics Clin Appl. 2016 Apr 12. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27068327

 

4

Manning EP.

Central nervous system oxygen toxicity and hyperbaric oxygen seizures.

Aerosp Med Hum Perform. 2016 May;87(5):477-86. Review.

http://www.ingentaconnect.com/content/asma/amhp/2016/00000087/00000005/art00009

 

5

Riwaldt S, Bauer J, Wehland M, Slumstrup L, Kopp S, Warnke E, Dittrich A, Magnusson NE, Pietsch J, Corydon TJ, Infanger M, Grimm D.

Pathways regulating spheroid formation of human follicular thyroid cancer cells under simulated microgravity conditions: A genetic approach.

Int J Mol Sci. 2016 Apr 8;17(4).

http://www.ncbi.nlm.nih.gov/pubmed/27070589

Note: A random positioning machine was used. This article may be obtained online without charge.

 

6

Wehland M, Warnke E, Frett T, Hemmersbach R, Hauslage J, Ma X, Aleshcheva G, Pietsch J, Bauer J, Grimm D.

The impact of hypergravity and vibration on gene and protein expression of thyroid cells.

Microgravity Sci Technol. 2016 Apr 7:1-14. [Epub ahead of print]

http://link.springer.com/article/10.1007%2Fs12217-015-9474-5

Note: Centrifugation and the Vibraplex vibration platform were used.

 

7

Yoo YM, Han TY, Kim HS.

Melatonin suppresses autophagy induced by clinostat in preosteoblast MC3T3-E1 cells.

Int J Mol Sci. 2016 Apr 8;17(4).

http://www.ncbi.nlm.nih.gov/pubmed/27070587

Note: A clinostat was used. This article may be obtained online without charge.

 

8

Cheema AK, Maier I, Dowdy T, Wang Y, Singh R, Ruegger PM, Borneman J, Fornace AJ Jr, Schiestl RH.

Chemopreventive metabolites are correlated with a change in intestinal microbiota measured in A-T mice and decreased carcinogenesis.

PLoS One. 2016 Apr 13;11(4):e0151190.

http://www.ncbi.nlm.nih.gov/pubmed/27073845

Note: This article may be obtained online without charge.

 

9

Sundblad P, Kölegard R, Migeotte PF, Delière Q, Eiken O.

The arterial baroreflex and inherent G tolerance.

Eur J Appl Physiol. 2016 Apr 12. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27072546

Note: Centrifugation was used.

 

10

Amini M, Hisdal J, Gjøvaag T, Kapetanovic N, Strand T-E, Owe JO, Hørthe JR, Mirtaheri P.

Near-infrared spectra in buccal tissue as a marker for detection of hypoxia.

Aerosp Med Hum Perform. 2016 May;87(5):498-504.

http://www.ingentaconnect.com/content/asma/amhp/2016/00000087/00000005/art00012

 

11

Ogneva IV, Biryukov NS.

Lecithin prevents cortical cytoskeleton reorganization in rat soleus muscle fibers under short-term gravitational disuse.

PLoS One. 2016 Apr 13;11(4):e0153650.

http://www.ncbi.nlm.nih.gov/pubmed/27073851

Note: Hindlimb unloading study. This article may be obtained online without charge.

 

12

Takemura A, Roy RR, Edgerton VR, Ishihara A.

Biochemical adaptations in a slow and a fast plantarflexor muscle of rats housed in small cages.

Aerosp Med Hum Perform. 2016 May;87(5):443-8.

http://www.ingentaconnect.com/content/asma/amhp/2016/00000087/00000005/art00004

 

13

Yamada K, Kazama Y, Mitra S, Marukawa Y, Arashida R, Abe T, Ishikawa T, Suzuki K.

Production of a thermal stress resistant mutant Euglena gracilis strain using Fe-ion beam irradiation.

Biosci Biotechnol Biochem. 2016 Apr 14:1-7. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27075598

 

14

Assländer L, Peterka RJ.

Sensory reweighting dynamics following removal and addition of visual and proprioceptive cues.

J Neurophysiol. 2016 Apr 13:jn.01145.2015. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27075544

 

15

Grundy JG, Nazar S, O'Malley S, Mohrenshildt MV, Shedden JM.

The effectiveness of simulator motion in the transfer of performance on a tracking task is influenced by vision and motion disturbance cues.

Hum Factors. 2016 Apr 11. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27068771

 

16

MacNeil RR, Che H, Khan M.

Human space exploration: Neurosensory, perceptual, and neurocognitive considerations.

UTMJ. 2016 Mar;93(2):19-26. Review.

http://utmj.org/index.php/UTMJ/article/view/1704

Note: From the Introduction: "The present review surveys a selection of the biomedical spaceflight literature to provide readers with an overview of what is known regarding the effects of spaceflight on the nervous system, with a particular emphasis placed on neurosensory, perceptual, and neurocognitive functions. These effects are addressed with respect to their implications for long-duration and exploration-class space missions." This article may be obtained online without charge.

 

17

Magee M, Sletten TL, Ferguson SA, Grunstein RR, Anderson C, Kennaway DJ, Lockley SW, Rajaratnam SM.

Associations between number of consecutive night shifts and impairment of neurobehavioral performance during a subsequent simulated night shift.

Scand J Work Environ Health. 2016 Apr 9. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27064758

Note: This article may be obtained online without charge.

 

18

Zeng LL, Liao Y, Zhou Z, Shen H, Liu Y, Liu X, Hu D.

Default network connectivity decodes brain states with simulated microgravity.

Cogn Neurodyn. 2016 Apr;10(2):113-20. Epub 2015 Oct 4.

http://www.ncbi.nlm.nih.gov/pubmed/27066149

Note: Bed rest study.

 

19

Mullington JM, Abbott SM, Carroll JE, Dijk DJ, Dinges DF, Gehrman PR, Ginsburg GS, Gozal D, Haack M, Lim DC, Macrea M, Pack AI, Plante DT, Teske JA, Zee PC.

Developing biomarker arrays predicting sleep and circadian-coupled risks to health.

Sleep. 2016 Apr 1;39(4):727-36.

http://www.ncbi.nlm.nih.gov/pubmed/26951388

 

20

Alberts BB, Selen LP, Bertolini G, Straumann D, Medendorp WP, Tarnutzer AA.

Dissociating vestibular and somatosensory contributions to spatial orientation.

J Neurophysiol. 2016 Apr 13:jn.00056.2016. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27075537

 

21

Frank SM, Wirth AM, Greenlee MW.

Visual-vestibular processing in the human sylvian fissure.

J Neurophysiol. 2016 Apr 13:jn.00009.2016. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27075535

 

22

Ranjbaran M, Katsarkas A, Galiana HL.

Vestibular compensation in unilateral patients often causes both gain and time constant asymmetries in the VOR.

Front Comput Neurosci. 2016 Apr 5;10:26.

http://www.ncbi.nlm.nih.gov/pubmed/27065839

Note: This article may be obtained online without charge.

 

23

Tribukait A, Ström A, Bergsten E, Eiken O.

Vestibular stimulus and perceived roll tilt during coordinated turns in aircraft and gondola centrifuge.

Aerosp Med Hum Perform. 2016 May;87(5):454-63.

http://www.ingentaconnect.com/content/asma/amhp/2016/00000087/00000005/art00006

Note: Centrifugation was used.

 

24

Perrineau F, Wimalasekera R, Effendi Y, Scherer GF.

Inhibition of auxin transport and auxin signaling and treatment with far red light induces root coiling in the phospholipase-A mutant ppla-I-1. Significance for surface penetration?

J Plant Physiol. 2016 Jun 1;196-197:53-9. Epub 2016 Apr 5.

http://www.ncbi.nlm.nih.gov/pubmed/27058428

 

25

Kasi P, Wright J, Khamis H, Birznieks I, van Schaik A.

The Bayesian decoding of force stimuli from slowly adapting type I fibers in humans.

PLoS One. 2016 Apr 14;11(4):e0153366.

http://www.ncbi.nlm.nih.gov/pubmed/27077750

Note: This article may be obtained online without charge.

 

26

Sánchez M, Ceci ML, Gutiérrez D, Anguita-Salinas C, Allende ML.

Mechanosensory organ regeneration in zebrafish depends on a population of multipotent progenitor cells kept latent by Schwann cells.

BMC Biol. 2016 Apr 7;14(1):27.

http://www.ncbi.nlm.nih.gov/pubmed/27055439

Note: This article may be obtained online without charge.

 

// end //

More status reports and news releases or top stories.

Please follow SpaceRef on Twitter and Like us on Facebook.

NanoRacks