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NASA Spaceline Current Awareness List #707 15 July 2016 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, July 15, 2016

 

Editor's note: NASA's various life sciences programs have prepared the SPACELINE Current Awareness updates since 1999 covering all aspects of space life science, gravitational biology, space medicine, and human factors. NASA does not maintain a website - nor does it have an archive of this resource online. However, SpaceRef does have a complete archive of SPACELINE updates all the way back to 1999
that can be accessed here: http://www.spaceref.com/news/mission.html?mid=188&pag

 

Papers deriving from NASA support:

 

1

Rizzardi LF, Kunz H, Rubins K, Chouker A, Quiriarte H, Sams C, Crucian BE, Feinberg AP.

Evaluation of techniques for performing cellular isolation and preservation during microgravity conditions.

npj Microgravity. 2016 Jul 14;2:16025.

http://www.nature.com/articles/npjmgrav201625

PI: A.P. Feinberg

Note: Parabolic flight results. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work was supported by funding from NASA (NNX14AH28G awarded to A.P.F. and a Division Innovation award from the NASA Biomedical Research and Environmental Sciences Division to B.E.C)."

 

2

Ott CM, Marshburn T, Nickerson CA.

The International Space Station: An extreme environment for key host-microbe discoveries.

Microbe (Washington). 2016 May;11(6):253-61.

http://www.asmscience.org/content/journal/microbe/10.1128/microbe.11.253.1

Journal Impact Factor: Not available for this journal.

Funding: No funding cited. C.M. Ott and T. Marshburn are affiliated with NASA Johnson Space Center.

 

3

Chang J, Luo Y, Wang Y, Pathak R, Sridharan V, Jones T, Mao XW, Nelson G, Boerma M, Hauer-Jensen M, Zhou D, Shao L.

Low doses of oxygen ion irradiation cause acute damage to hematopoietic cells in mice.

PLoS One. 2016 Jul 1;11(7):e0158097.

http://www.ncbi.nlm.nih.gov/pubmed/27367604

PIs: M. Boerma/X.W. Mao/G. Nelson/M. Hauer-Jensen/NSBRI Center for Research in Cardiac, Vascular, and Acute Effects of Space Radiation

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.057

Funding: "The study was supported in part by the National Space Biomedical Research Institute through NCC 9-58, Centers of Biomedical Research Excellence (P20, GM109005), Arkansas Research Alliance Scholarship, and Rockefeller Leukemia and Lymphoma Research Endowment."

 

4

Gao X, Sishc BJ, Nelson CB, Hahnfeldt P, Bailey SM, Hlatky L.

Radiation-induced reprogramming of pre-senescent mammary epithelial cells enriches putative CD44(+)/CD24(-/low) stem cell phenotype.

Front Oncol. 2016 Jun 14.;6:138.

http://www.ncbi.nlm.nih.gov/pubmed/27379202

PIs: S.M. Bailey, L. Hlatky

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "Support for this research from NASA (NNX08AB65G and NNX14AS02G to SB, NNX13AJ01G to LH) and National Cancer Institute (U54 CA149233 to LH) are gratefully acknowledged."

 

5

Gridley DS, Pecaut MJ.

Changes in the distribution and function of leukocytes after whole-body iron ion irradiation.

J Radiat Res. 2016 Jul 5. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27380804

Note: This article may be obtained online without charge.

Journal Impact Factor: 1.536

Funding: "This work was supported by the National Aeronautics and Space Administration [grant number NCC9-79], the Department of Radiation Medicine of the Loma Linda University Medical Center and the Department of Basic Sciences at Loma Linda University."

______________________________________________________

 

Other papers of interest:

 

1

Poulet L, Fontaine JP, Dussap CG.

Plant’s response to space environment: A comprehensive review including mechanistic modelling for future space gardeners.

Bot Lett. 2016 Jul 7:1-11. [Article in Press] Review.

http://www.tandfonline.com/doi/full/10.1080/23818107.2016.1194228

Note: Experiments flown on BIOS, Biosatellite, Mir, Salyut, STS, and ISS are discussed. From the abstract: "This review intends to list the main spaceflight effects to take into account for plant growth in space, as well as to give an overview of the current state of plant-growth hardware while stressing the challenges associated with their development."

 

2

Wang J, Lewis RF.

Contribution of intra-vestibular sensory conflict to motion sickness and dizziness in migraine disorders.

J Neurophysiol. 2016 Jul 6:jn.00345.2016. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27385797

 

3

Atherton PJ, Greenhaff PL, Phillips SM, Bodine SC, Adams CM, Lang CH.

Control of skeletal muscle atrophy in response to disuse: Clinical/preclinical contentions and fallacies of evidence.

Am J Physiol Endocrinol Metab. 2016 Jul 5:ajpendo.00257.2016. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27382036

Note: From the Introduction: "This article is a written representation of a symposium at Experimental Biology (San Diego, 2016) which focused on the mechanisms of disuse atrophy in skeletal muscle." Studies reviewed discussed a number of disuse methods including bed rest, limb immobilization, and abrupt reductions in physical activity.

 

4

Cécile P, Koulmann N, Claustre A, Jarzaguet M, Serrurier B, Combaret L, Béchet D, Bigard X, Attaix D, Taillandier D.

UBE2D2 is not involved in MuRF1-dependent muscle wasting during hindlimb suspension.

Int J Biochem Cell Biol. 2016 Jul 1. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27378730

Note: Hindlimb unloading was used.

 

5

Galvan E, Arentson-Lantz E, Lamon S, Paddon-Jones D.

Protecting skeletal muscle with protein and amino acid during periods of disuse.

Nutrients. 2016 Jul 1;8(7):E404. Review.

http://www.ncbi.nlm.nih.gov/pubmed/27376322

Note: A number of bed rest studies are included in the review. This article may be obtained online without charge.

 

6

Hamrick MW, McGee-Lawrence ME, Frechette DM.

Fatty infiltration of skeletal muscle: Mechanisms and comparisons with bone marrow adiposity.

Front Endocrinol (Lausanne). 2016 Jun 20;7:69.

http://www.ncbi.nlm.nih.gov/pubmed/27379021

Note: This article may be obtained online without charge.

 

7

Lamboley CR, Wyckelsma VL, Perry BD, McKenna MJ, Lamb GD.

Effect of 23-day muscle disuse on sarcoplasmic reticulum Ca2+ properties and contractility in human type I and type II skeletal muscle fibers.

J Appl Physiol (1985). 2016 Jun 30:jap.00337.2016. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27365282

Note: Unilateral lower limb suspension was used.

 

8

Mirzoev TM, Tyganov SA, Shenkman BS.

Akt-dependent and Akt-independent pathways are involved in protein synthesis activation during reloading of disused soleus muscle.

Muscle Nerve. 2016 Jul 1. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27367189

Note: Hindlimb unloading was used.

 

9

Ambroglini F, Battiston R, Burger WJ.

Evaluation of superconducting magnet shield configurations for long duration manned space missions.

Front Oncol. 2016 Jun 8;6:97.

http://www.ncbi.nlm.nih.gov/pubmed/27376023

Note: A series of three studies that examined the use of superconducting magnets as radiation shielding in long-duration space missions have been conducted over the last 5 years, funded successively by European Space Agency (ESA), the NASA Innovative Advanced Concepts (NIAC) program, and the Union European’s Seventh Framework Programme (FP7). A summary of the results of the studies is presented. This article may be obtained online without charge.

 

10

Ando K, Goodhead DT.

Dependence and independence of survival parameters on linear energy transfer in cells and tissues.

J Radiat Res. 2016 Jul 5. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27380803

Note: This article may be obtained online without charge.

 

11

Chuard D, Anthonipillai V, Dendale R, Nauraye C, Khan E, Mabit C, De Marzi L, Narici L.

Mechanisms of phosphene generation in ocular proton therapy as related to space radiation exposure.

Life Sci Space Res. 2016 Jul 7. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552416300104

 

12

Shim G, Normil MD, Testard I, Hempel WM, Ricoul M, Sabatier L.

Comparison of individual radiosensitivity to gamma-rays and carbon ions.

Front Oncol. 2016 Jun 13;6:137.

http://www.ncbi.nlm.nih.gov/pubmed/27379201

Note: This article may be obtained online without charge.

 

13

Lubeck AJ, Bos JE, Stins JF.

Framing visual roll-motion affects postural sway and the subjective visual vertical.

Atten Percept Psychophys. 2016 Jun 30. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27363414

Note: This article may be obtained online without charge.

 

14

Uddin SM, Richbourgh B, Ding Y, Hettinghouse A, Komatsu DE, Qin YX, Liu CJ.

Chondro-protective effects of low intensity pulsed ultrasound.

Osteoarthritis Cartilage. 2016 Jun 27. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27364595

 

 

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