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NASA Spaceline Current Awareness List #713 2 September 2016 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, September 2, 2016

 

Editor's note: NASA's various life sciences programs have prepared the SPACELINE Current Awareness updates since 1999 covering all aspects of space life science, gravitational biology, space medicine, and human factors. NASA does not maintain a website - nor does it have an archive of this resource online. However, SpaceRef does have a complete archive of SPACELINE updates all the way back to 1999
that can be accessed here: http://www.spaceref.com/news/mission.html?mid=188&pag

 

Papers deriving from NASA support:

 

1

Shi Z, Chapes SK, Ben-Arieh D, Wu CH.

An agent-based model of a hepatic inflammatory response to Salmonella: A computational study under a large set of experimental data.

PLoS One. 2016 Aug 24;11(8):e0161131.

http://www.ncbi.nlm.nih.gov/pubmed/27556404

PIs: S.K. Chapes, M. Pecaut

Note: This article may be obtained online without charge.

Journal Impact Factor: 3.057

Funding: "ZZS was supported by China Scholarship Council. SKC has been supported by National Institutes of Health (NIH) grant GM103418 and National Aeronautics and Space Administration (NASA) grants NNX13AN34G and NNX15AB45G. DBA and CW have been supported by the Healthcare Operations Resource Center at Kansas State University."

 

2

Morris C, Tomimatsu N, Burma S, Jalinot P.

INT6/EIF3E controls the RNF8-dependent ubiquitylation pathway and facilitates DNA double-strand break repair in human cells.

Cancer Res. 2016 Aug 22. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27550454

PI: S. Burma

Journal Impact Factor: 8.556

Funding: "This work was supported by grants from Association pour la Recherche sur le Cancer, Comité départemental de la Savoie de la Ligue Nationale Contre le Cancer, and from the Agence Nationale de la Recherche (ANR-2010-BLAN-1235 01 FURETT) to P. Jalinot. S. Burma is supported by grants from the National Institutes of Health (RO1CA149461, RO1CA197796 and R21CA202403) and the National Aeronautics and Space Administration (NNX16AD78G)."

 

3

Doh JH, Moore AB, Celen I, Moore MT, Sabanayagam CR.

ChIP and chips: Introducing the WormPharm for correlative studies employing pharmacology and genome-wide analyses in C. elegans.

2016. 2016 Jun 10;3(2):e44.

http://www.jbmethods.org/jbm/article/view/109

PI: C.R. Sabanayagam

Note: This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "We would like to thank NASA’s Space Biology program for their interest in this project and financial support through grant award NNX13AM08G."

 

4

De Witt JK, English KL, Crowell JB, Kalogera KL, Guilliams ME, Nieschwitz BE, Hanson AM, Ploutz-Snyder LL.

Isometric mid-thigh pull reliability and relationship to deadlift 1RM.

J Strength Cond Res. 2016 Aug 18. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27548797

PI: L. Ploutz-Snyder, J.K. De Witt

Journal Impact Factor: 1.978

Funding: "The authors would like to thank the NASA Human Research Program for funding this project."

 

5

Kearney AR.

Mitigating risks to psychological and behavioral health in long-duration spaceflight: Towards a portfolio of countermeasures.

Houston, TX: NASA Johnson Space Center, 2016 Aug. 132 p. NASA/TM-2016-219275.

https://ston.jsc.nasa.gov/collections/TRS/listfiles.cgi?DOC=TM-2016-219275

Note: This publication may be obtained online without charge.

Journal Impact Factor: Not applicable

Funding: "This project was funded by the NASA Human Research Program (HRP), Behavioral Health and Performance (BHP) Group through the Wyle Science, Technology & Engineering Group."

 

6

Kearney AR.

Team health and performance in spaceflight habitats: Risks, countermeasures, and research recommendations.

Houston, TX: NASA Johnson Space Center, 2016 Aug. 76 p. NASA/TM-2016-219274.

https://ston.jsc.nasa.gov/collections/TRS/listfiles.cgi?DOC=TM-2016-219274

Note: This publication may be obtained online without charge.

Journal Impact Factor: Not applicable

Funding: "This project was funded by the NASA Human Research Program (HRP), Behavioral Health and Performance (BHP) Element under NASA grant NNJ14HK45P."

 

7

Littlepage GE, Hein MB, Moffett RG 3rd, Craig PA, Georgiou AM.

Team training for dynamic cross-functional teams in aviation: Behavioral, cognitive, and performance outcomes.

Hum Factors. 2016 Aug 22. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27549389

Journal Impact Factor: 1.370

Funding: "The development of the simulation lab was supported by NASA Grant No. NNX10AI11G."

 

8

El-Ashmawy M, Coquelin M, Luitel K, Batten K, Shay JW.

Organotypic culture in three dimensions prevents radiation-induced transformation in human lung epithelial cells.

Sci Rep. 2016 Aug 19;6:31669.

http://www.ncbi.nlm.nih.gov/pubmed/27539227

PIs: J.W. Shay; A.J. Fornace/K. Batten/J.W. Shay/NSCOR; J.D. Minna/J.W. Shay/NSCOR

Note: This article may be obtained online without charge.

Journal Impact Factor: 5.228

Funding: "This work was supported in part by the National Aeronautics and Space Administration (NNJ05HD36G, NNX09AU95G, and NNX11AC15G); the National Cancer Institute (Lung SPORE P50CA70907); the Howard Hughes Medical Institute Gilliam Fellowship; and the Center for Excellence in Genomics Medicine Research at King Abdulaziz University, Saudi Arabia. This work was performed in laboratories constructed with support from National Institute of Health grant C06 RR30414. We would also like to acknowledge The Genomics Shared Resource and Cancer Center Support Grant."

 

9

Suman S, Kumar S, Fornace AJ, Datta K.

Space radiation exposure persistently increased leptin and IGF1 in serum and activated leptin-IGF1 signaling axis in mouse intestine.

Sci Rep. 2016 Aug 25;6:31853.

http://www.ncbi.nlm.nih.gov/pubmed/27558773

PIs: K. Datta; A.J. Fornace/K. Datta/NSCOR

Note: This article may be obtained online without charge.

Journal Impact Factor: 5.228

Funding: "This study is supported in part by NASA Grant# NNX13AD58G and NNX15AI21G. We acknowledge the Histopathology and Tissue Shared Resources supported by Award Number P30CA051008 from the National Cancer Institute."

______________________________________________________

 

Other papers of interest:

 

1

Fix DK, Hardee JP, Bateman TA, Carson JA.

The effect of irradiation on Akt signaling in atrophying skeletal muscle.

J Appl Physiol (1985). 2016 Aug 25:jap.00218.2016. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27562841

Note: Hindlimb unloading study.

 

2

Kent JA, Fitzgerald LF.

In vivo mitochondrial function in aging skeletal muscle: Capacity, flux and patterns of use.

J Appl Physiol (1985). 2016 Aug 18:jap.00583.2016. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/27539499

 

3

Jakeman SA, Henry CN, Martin BR, McCabe GP, McCabe LD, Jackson GS, Peacock M, Weaver CM.

Soluble corn fiber increases bone calcium retention in postmenopausal women in a dose-dependent manner: A randomized crossover trial.

Am J Clin Nutr. 2016 Jul 27. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27465372

 

4

Zhang LF, Zhang S.

Systems specificity in responsiveness to intermittent artificial gravity during simulated microgravity in rats.

Sheng Li Xue Bao. 2016 Aug 25;68(4):391-402. Chinese.

http://www.ncbi.nlm.nih.gov/pubmed/27546500

Note: The methods used for artificial gravity and weightlessness simulation are not identified in the English abstract.

 

5

Dzakovich MP, Ferruzzi MG, Mitchell CA.

Manipulating sensory and phytochemical profiles of greenhouse tomatoes using environmentally relevant doses of ultraviolet radiation.

J Agric Food Chem. 2016 Aug 26. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27561664

 

6

Sullivan S, Takemiya A, Kharshiing E, Cloix C, Shimazaki KI, Christie JM.

Functional characterisation of Arabidopsis phototropin 1 in the hypocotyl apex.

Plant J. 2016 Aug 22. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27545835

 

7

Schuster H, Peck SL.

Mars ain't the kind of place to raise your kid: Ethical implications of pregnancy on missions to colonize other planets.

Life Sci Soc Policy. 2016 Dec;12(1):10. Epub 2016 Aug 25.

http://www.ncbi.nlm.nih.gov/pubmed/27558392

Note: This article may be obtained online without charge.

 

8

Larue GS, Rakotonirainy A, Haworth NL.

A simulator evaluation of effects of assistive technologies on driver cognitive load at railway-level crossings.

J Transport Safety Secur. 2016;8(Suppl 1):56-69. Epub 2015 Nov 5.

http://www.tandfonline.com/doi/full/10.1080/19439962.2015.1055413

Note: The NASA Task Load Index was used. This article may be obtained online without charge.

 

 

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