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NASA Spaceline Current Awareness List #715 16 September 2016 (Space Life Science Research Results)

Status Report From: Spaceline
Posted: Friday, September 16, 2016

 

Editor's note: NASA's various life sciences programs have prepared the SPACELINE Current Awareness updates since 1999 covering all aspects of space life science, gravitational biology, space medicine, and human factors. NASA does not maintain a website - nor does it have an archive of this resource online. However, SpaceRef does have a complete archive of SPACELINE updates all the way back to 1999 that can be accessed here: http://www.spaceref.com/news/mission.html?mid=188&pag 

 

Papers deriving from NASA support:

 

1

Heath-Heckman EA, Foster J, Apicella MA, Goldman WE, McFall-Ngai M.

Environmental cues and symbiont MAMPs function in concert to drive the daily remodeling of the crypt-cell brush border of the Euprymna scolopes light organ.

Cell Microbiol. 2016 Apr 8. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27062511

PI: J. Foster

Journal Impact Factor: 4.460

Funding: "This work was supported by grants from National Institutes of Health (NIH) R01-AI50661 (to MM-N, EGR, MAA and WEG), R01-OD11024 (to EGR and MM-N), and R01-AI108255 (to MAA), and National Science Foundation IOS 0817232 (to MMN & EGR). EACH-H was supported by NRSA T-32 GM07215." The LPS antibody work contributed by J. Foster was supported by NASA Space Biology Award NNX13AM44G.

 

2

Judex S, Zhang W, Donahue LR, Ozcivici E.

Genetic and tissue level muscle-bone interactions during unloading and reambulation.

J Musculoskelet Neuronal Interact. 2016 Sep 7;16(3):174-82.

http://www.ncbi.nlm.nih.gov/pubmed/27609032

PI: S. Judex

Note: Hindlimb unloading study. This article may be obtained online without charge at http://www.ismni.org/jmni/.

Journal Impact Factor: 1.638

Funding: "This study was kindly funded by NASA NAG 9-1499 and NNX12AL25G."

 

3

Yuan P, Koppelmans V, Reuter-Lorenz PA, De Dios YE, Gadd NE, Wood SJ, Riascos R, Kofman IS, Bloomberg JJ, Mulavara AP, Seidler RD.

Increased brain activation for dual tasking with 70-days head-down bed rest.

Front Syst Neurosci. 2016 Aug 23;10:71.

http://www.ncbi.nlm.nih.gov/pubmed/27601982

PIs: R.D. Seidler; V. Koppelmans, NSBRI Postdoctoral Fellowship Program

Note: Bed rest study. This article may be obtained online without charge.

Journal Impact Factor: Not available for this journal

Funding: "This work is supported by grants from the National Space Biomedical Research Institute (NASA NCC 9-58, MA02701, and PF04101), from the National Aeronautics and Space Administration (NASA; NNX11AR02G) and NASA Flight Analogs Project, and the National Institutes of Health, and National Center for Advancing Translational Sciences, 1UL1RR029876-01."

 

4

Brainard GC, Barger LK, Soler RR, Hanifin JP.

The development of lighting countermeasures for sleep disruption and circadian misalignment during spaceflight.

Curr Opin Pulm Med. 2016 Sep 7. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/27607152

PIs: G.C. Brainard, L.K. Barger, C.A. Czeisler

Note: From the abstract: "The review addresses the development of a new solid-state lighting system for the International Space Station (ISS) that is intended to enhance the illumination of the working and living environment of astronauts and to improve sleep, circadian entrainment, and daytime alertness."

Journal Impact Factor: 3.079

Funding: "The work was supported, in part, by grants from NASA #NNX15AC14G, #NNX08AD66A, #NNX09AM68G; NASA cooperative agreement NCC 9-119; NSBRI under NASA Cooperative Agreement NCC 9-58; Center for Lighting Enabled Systems and Applications ERC under NSF EEC-0812056; The Institute for Integrative Health, and the Philadelphia Section of the Illuminating Engineering Society. The NSF Graduate Research Fellowship Program supports R.R.S."

 

5

Hughes AM, Gregory ME, Joseph DL, Sonesh SC, Marlow SL, Lacerenza CN, Benishek LE, King HB, Salas E.

Saving lives: A meta-analysis of team training in healthcare.

J Appl Psychol. 2016 Sep;101(9):1266-304.

http://www.ncbi.nlm.nih.gov/pubmed/27599089

PI: E. Salas

Journal Impact Factor: 3.004

Funding: "This work was supported in part by contract NNX16AB08G with the National Aeronautics and Space Administration (NASA) to Rice University."

 

6

Johnson AW, Duda KR, Sheridan TB, Oman CM.

A closed-loop model of operator visual attention, situation awareness, and performance across automation mode transitions.

Hum Factors. 2016 Sep 1. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27591207

PI: K.R. Duda

Journal Impact Factor: 1.270

Funding: "This research was supported by the National Space Biomedical Research Institute through NASA NCC 9-58, Project HFP02001, and by the Charles Stark Draper Laboratory."

 

7

Sebok A, Wickens CD.

Implementing lumberjacks and black swans into model-based tools to support human-automation interaction.

Hum Factors. 2016 Sep 2. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27591210

PI: A. Sebok

Note: From the abstract: "The lumberjack analogy describes the effects of imperfect automation on operator performance.  . . Black swans are the rare and unexpected failures of imperfect automation."

Journal Impact Factor: 1.370

Funding: "The projects described in this paper were supported by three NASA grants: NNX07AT79A (ADAT), NNX09AM81G (MIDAS-FAST), and NNX12AE69G (S-PRINT)."

______________________________________________________

 

Other papers of interest:

 

1

Povysheva TV, Rezvyakov PN, Shaimardanova GF, Nikolskii EE, Islamov RR, Chelyshev YA, Grygoryev AI.

Myelinated fibers of the mouse spinal cord after a 30-day space flight.

Dokl Biol Sci. 2016 Jul;469(1):163-6. Epub 2016 Sep 7.

http://www.ncbi.nlm.nih.gov/pubmed/27595822

Note: Bion-M1 results.

 

2

Yamazaki C, Fujii N, Miyazawa Y, Kamada M, Kasahara H, Osada I, Shimazu T, Fusejima Y, Higashibata A, Yamazaki T, Ishioka N, Takahashi H.

The gravity-induced re-localization of auxin efflux carrier CsPIN1 in cucumber seedlings: Spaceflight experiments for immunohistochemical microscopy.

npj Microgravity. 2016 Sep 15;2:16030.

http://www.nature.com/articles/npjmgrav201630

Note: ISS results. This article may be obtained online without charge.

 

3

Cerri M, Tinganelli W, Negrini M, Helm A, Scifoni E, Tommasino F, Sioli M, Zoccoli A, Durante M.

Hibernation for space travel: Impact on radioprotection.

Life Sci Space Res. 2016 Sep 13. [Article in Press]

http://www.sciencedirect.com/science/article/pii/S2214552416300542

 

4

Zhang Y, Aguilar OA, Storey KB.

Transcriptional activation of muscle atrophy promotes cardiac muscle remodeling during mammalian hibernation.

PeerJ. 2016;4:e2317. Epub 2016 Aug 11.

http://www.ncbi.nlm.nih.gov/pubmed/27602284

Note: This article may be obtained online without charge.

 

5

Zhang Y, Tessier SN, Storey KB.

Inhibition of skeletal muscle atrophy during torpor in ground squirrels occurs through downregulation of MyoG and inactivation of Foxo4.

Cryobiology. 2016 Sep 1. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27593478

 

6

Giorgi M, Verbruggen SW, Lacroix D.

In silico bone mechanobiology: Modeling a multifaceted biological system.

Wiley Interdiscip Rev Syst Biol Med. 2016 Sep 7. [Epub ahead of print] Review.

http://www.ncbi.nlm.nih.gov/pubmed/27600060

Note: This article may be obtained online without charge.

 

7

Ortuño MJ, Robinson ST, Subramanyam P, Paone R, Huang YY, Guo XE, Colecraft HM, Mann JJ, Ducy P.

Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect.

Nat Med. 2016 Sep 5. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27595322

 

8

Robling AG, Kang KS, Bullock WA, Foster WH, Murugesh D, Loots GG, Genetos DC.

Sost, independent of the non-coding enhancer ECR5, is required for bone mechanoadaptation.

Bone. 2016 Sep 4;92:180-8. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27601226

 

9

Tiwari AK, Prasad J.

Computer modelling of bone's adaptation: The role of normal strain, shear strain and fluid flow.

Biomech Model Mechanobiol. 2016 Sep 1. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27585446

 

10

Aare S, Spendiff S, Vuda M, Elkrief D, Perez A, Wu Q, Mayaki D, Hussain SN, Hettwer S, Hepple RT.

Failed reinnervation in aging skeletal muscle.

Skelet Muscle. 2016 Sep 1;6(1):29.

http://www.ncbi.nlm.nih.gov/pubmed/27588166

Note: This article may be obtained online without charge.

 

11

Gastebois C, Chanon S, Rome S, Durand C, Pelascini E, Jalabert A, Euthine V, Pialoux V, Blanc S, Simon C, Lefai E.

Transition from physical activity to inactivity increases skeletal muscle miR-148b content and triggers insulin resistance.

Physiol Rep. 2016 Sep;4(17).

http://www.ncbi.nlm.nih.gov/pubmed/27597765

Note: This article may be obtained online without charge.

 

12

Nikitaki Z, Nikolov V, Mavragani IV, Mladenov E, Mangelis A, Laskaratou DA, Fragkoulis GI, Hellweg CE, Martin OA, Emfietzoglou D, Hatzi VI, Terzoudi GI, Iliakis G, Georgakilas AG.

Measurement of complex DNA damage induction and repair in human cellular systems after exposure to ionizing radiations of varying linear energy transfer (LET).

Free Radic Res. 2016 Sep 5:1-45. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27593437

 

13

Salehi MS, Mirzaii-Dizgah I, Vasaghi-Gharamaleki B, Zamiri MJ.

Effect of hindlimb unloading on stereological parameters of the motor cortex and hippocampus in male rats.

Neuroreport. 2016 Sep 7. [Epub ahead of print]

http://www.ncbi.nlm.nih.gov/pubmed/27607230

Note: Hindlimb unloading study.

 

// end //

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